Optimizing Xevo G2-XS QTof Quadrupole Settings to Increase Sensitivity and Dynamic Range for the Analysis of Trastuzumab
Technical notes | 2018 | WatersInstrumentation
LC/TOF, LC/HRMS, LC/MS, LC/MS/MS
IndustriesPharma & Biopharma
ManufacturerWaters
Key wordstrastuzumab, dtyihwvr, ftisadtsk, mass, window, peptide, quadrupole, selection, conc, charge, hrms, interference, sensitivity, isobaric, modalities, optimizing, brief, matrix, selectivity, close, peak, peptides, fragment, response, complement, tof, biotherapeutic, serve, plasma, precursor, encephalin, surrogate, often, closely, sensitive, transmission, reduce, led, using, complex, digestion, quantitative, technology, can, eluting, min, height, interferences, integration, product
Similar PDF
Comparison of Tandem and High Resolution Mass Spectrometry for the Quantification of the Monoclonal Antibody, Trastuzumab in Plasma
2018|Waters|Technical notes
[ TECHNOLOGY BRIEF ] Comparison of Tandem and High Resolution Mass Spectrometry for the Quantification of the Monoclonal Antibody, Trastuzumab in Plasma Mary Lame, Caitlin Dunning, Yun Alelyunas, and Mark Wrona Waters Corporation, Milford, MA, USA Demand for bioanalytical quantification…
Key words
ftisadtsk, ftisadtskdtyihwvr, dtyihwvrtrastuzumab, trastuzumabquadrupole, quadrupoletandem, tandemxevo, xevopeptide, peptidebrief, briefmrm, mrmbioanalytical, bioanalyticalweighting, weightinglod, lodperformance, performancemass, massaccuracy
LC-MS Quantification of Trastuzumab Using Pellet Digestion and ProteinWorks eXpress Direct Digest Kits
2016|Waters|Applications
LC-MS Quantification of Trastuzumab Using Pellet Digestion and ProteinWorks eXpress Direct Digest Kits Mary Lame, Paula Orens, Sherri Naughton, and Erin Chambers Waters Corporation, Milford, MA, USA G OA L To demonstrate the compatibility of ProteinWorks™ Kits with pellet digestion…
Key words
ppt, pptarea, areaalbumin, albumintrastuzumab, trastuzumabdigestion, digestionpellet, pelletproteinworks, proteinworksconc, concpeptide, peptidepeptides, peptidesexpress, expressdtyihwvr, dtyihwvrdirect, directtryptic, trypticftisadtsk
Waters Application Notes - ProteinWorks
2016|Waters|Guides
Waters Application Notes ProteinWorks OUR SCIENTISTS Erin E. Chambers As a principal scientist, Erin has been working almost exclusively on peptide and protein bioanalysis for the last seven years, while managing small and large molecule bioanalysis and clinical research applications…
Key words
proteinworks, proteinworksdigest, digestexpress, expressarea, areapeptide, peptidekit, kittrastuzumab, trastuzumabgeneric, genericplasma, plasmadigestion, digestionftfsldtsk, ftfsldtskmurine, murineantibody, antibodyprotein, proteinsignature
PEPTIDE AND PROTEIN BIOANALYSIS
2016|Waters|Guides
[ APPLICATION NOTEBOOK ] PEPTIDE AND PROTEIN BIOANALYSIS [ OUR SCIENTISTS ] Yun Alelyunas, PhD Before coming to Waters in 2012, Yun Alelyunas was a principal scientist and team leader at AstraZeneca for 20 years where she was involved in…
Key words
ionkey, ionkeypeptide, peptideplasma, plasmaquantification, quantificationhuman, humanarea, areaxevo, xevoinsulin, insulinprotein, proteinuplc, uplcpeptides, peptidesmrm, mrmproteinworks, proteinworksantibody, antibodyusing