Thermo Scientific Hypersil GOLD Peptide Columns

Resolve peptide challenges with one column - NEW Hypersil GOLD Peptide.

Achieve consistent retention of all peptides, including hydrophilic ones, and resolve deamidated species. Designed for stability and lot-to-lot consistency, this column meets the needs of biopharmaceutical product development and manufacturing control.

Hypersil GOLD Peptide column performance is assured through dual quality confirmation, including a peptide-based QC test, ensures confidence in ultrapure silica, ligand bonding, and column packing for unparalleled sequence coverage and higher peak capacity compared to other peptide columns.

Consistent, Reliable Results

• Enjoy excellent reproducibility with minimal RSD%, ensuring consistency from column-to-column and lot-to-lot.

Optimized Peptide Retention - Retain More, Discover More

• Our column uniquely holds onto hydrophilic peptides, ensuring no critical data is missed.

Exceptional Peak Capacity - Separate with Superiority

• Achieve higher peak capacity for detailed and clear separations, ensuring every component is distinctly resolved.

Advanced PTM Analysis - Decipher Complex Modifications

• Efficiently separate key post-translational modifications like deamidation, crucial for in-depth protein analysis. Excellent peak shape for peptides using either FA- or TFA-containing mobile phases.

Unparalleled Sequence Coverage - See the Full Picture

• High sequence coverage provides a comprehensive analysis, revealing the true complexity of your samples.

Specifications

• Endcapped: Yes
• For use with: LC/MS
• Max. Pressure: 14503 psi (1000 bar)
• Packing Material: Spherical, Fully Porous, Ultrapure Silica
• USP Type: L1
• Surface Area: 220 m²/g
• Temperature: 60°C
• Carbon Load: 11%
• Phase: Reversed Phase
• Pore Size: 175 Å
• pH: 2 to 11

About the Hypersil GOLD Family of HPLC Columns

Meet the challenges of modern chromatography with state-of-the-art columns that provide outstanding performance and consistent separations. Twelve different column chemistries are available so you can optimize separations and maximize productivity. Get outstanding peak shapes in reversed phase, ion exchange, HILIC, or normal phase chromatography.

Thermo Fisher Scientific: Hypersil GOLD Columns

• Excellent peak symmetry
  • Hypersil GOLD columns produce highly symmetrical peaks, which facilitate the detection of low-level impurities that elute immediately after the main component. When there is even minor tailing, small impurity peaks can elute on the shoulder of the main peak, complicating the integration process.
• Narrow peaks for outstanding efficiency
• Enhanced sensitivity and improved resolution
• Exceptional reproducibility for reliable chromatography, column after column
• Solutions for high-throughput screening
• 1.9, 3, and 5 μm particle sizes for all your separation needs

Thermo Fisher Scientific: Hypersil GOLD Columns: Peak symmetry