Thermo Scientific Syncronis HILIC HPLC Columns

Ensure consistent, predictable separations of polar and hydrophilic analytes with Thermo Scientific™ Syncronis™ HILIC LC Columns. Highly pure, high surface area silica and dense stationary phase coverage minimize secondary interactions and deliver reproducible high-resolution separations. The zwitterionic stationary phase results in a neutral, highly polar surface and provides alternative selectivity to C18 columns without ion-pairing or derivatization. The highly organic mobile phases used with Syncronis HILIC phases facilitate efficient desolvation in ESI-MS detection and improved sensitivity.

Manufactured and rigorously tested in ISO 9000 facilities, these columns are designed to meet a range of analytical needs including fast method development, quantitative analysis and quality control.

Highly Reproducible Separations

• Rigorously tested stationary phase bonded to the highest quality silica ensures consistent, predictable LC performance

Excellent Peak Shapes for Enhanced Resolution and Sensitivity

• Dense surface coverage of silica minimizes secondary interactions and peak tailing

Exceptional Column-to-Column Consistency

• Manufactured, packed, and tested in ISO-9000-accredited facilities
• Every column individually tested to meet stringent retention, efficiency, and peak symmetry specifications
• Enhanced automated packing process

Alternative Selectivity

• Zwitterionic bonded phase enhances retention of polar and hydrophilic analytes
• No need for ion-pair or derivatization

Enhanced Sensitivity with MS Detection

• Highly organic mobile phase facilitates desolvation in ESI-MS

Available in Three Particle Sizes

• 1.7μm for rapid ultrahigh-performance LC (UHPLC) separations
• 3μm and 5μm for more traditional HPLC analysis

Specifications

• Column type: HILIC
• Max. Pressure: 5800 psi (400 bar)
• Packing Material: Spherical, Fully Porous, Ultrapure Silica
• Stationary phase: Zwitterionic
• Surface Area: 320 m²/g
• Temperature: 60°C
• Carbon load: 5%
• Phase: HILIC
• Pore Size: 100 Å
• pH: 2 to 8

Syncronis HPLC and UHPLC Columns

Enter a new world of chromatography

When developing a new method, one of the most important goals for the chromatographer is to achieve a consistent, reproducible separation. This makes selecting an HPLC column that offers highly-reproducible results essential to attaining this goal.

Features of Syncronis columns

Thermo Scientific Syncronis LC columns achieve high levels of consistency and reproducibility through:

• Highly-pure, high-surface-area silica
• Dense bonding and double endcapping
• Stringent manufacturing and testing protocols