Arg-BPC-157 analysis

This analysis is designed to confirm the identity and determine the amount and peptide purity of Arg-BPC-157 in oral products and raw API powders. HPLC testing provides information about the BPC-157 content of the sample and the proportion of the main peptide component relative to chromatographically detectable impurities.

Arg-BPC-157

Arg-BPC-157 is a form of the BPC-157 peptide containing an arginine salt. The presence of the arginine salt distinguishes this product from standard BPC-157 and requires an appropriate analytical procedure.

The analysis measures only the amount of BPC-157 itself. The amount of arginine or arginine salt is not included in the result.

Samples that do not contain an arginine salt should be submitted for the standard BPC-157 analysis instead.

What the Analysis Determines

• Identity of Arg-BPC-157
• Amount of BPC-157 in the sample
• Peptide purity
• BPC-157 content per tablet or capsule
• Optional mass-by-mass purity for raw API powders

Analysis Parameters

• Target compound: Arg-BPC-157
• Other name: BPC-157 with arginine salt
• Testing method: HPLC
• Detection limit: less than one twentieth of the usual dosage
• Result format for oral products: mg per tablet or capsule and peptide purity
• Alternative result format: m/m purity and peptide purity
• Minimum oral sample: 3 tablets or capsules
• Minimum raw API powder sample: 30 mg in a sealed glass vial to prevent moisture absorption
• Average turnaround time: 7 business days

Important Notice

The reported amount refers exclusively to BPC-157. The arginine content and the total amount of Arg-BPC-157 including the arginine salt are not measured separately.

The alternative m/m purity result format is intended exclusively for raw API powders. For tablets and capsules, the standard result format provides the amount of BPC-157 in mg per tablet or capsule together with peptide purity.

Additional Analyses

TFA Analysis

• Detection and measurement of trifluoroacetic acid (TFA) in the sample. Results are reported in mg per vial.

Raw Data

• Delivery of the available raw analytical data from the primary test and all applicable additional analyses.

Fentanyl Presence Analysis

Alternative Result Format – m/m Purity

• Alternative reporting of the result as mass-by-mass purity. This option is intended exclusively for raw API powders.

Variance Testing

• Analysis of multiple sample units to assess variation within a single batch. All submitted samples must originate from the same batch of the same product.

pH Measurement

Endotoxin Analysis

• Measurement of bacterial endotoxins, particularly lipopolysaccharides (LPS), in the sample. This analysis is available only for finished products and should not be ordered for raw powders.
• The standard test provides accurate results up to 10 EU per vial. Values above 10 EU per vial are estimated and require an additional test with a different dilution for precise determination. Sending two vials is therefore recommended.
• Where endotoxin levels above 10 EU per vial are expected, the method can be calibrated for the higher range in advance.

CHNS Mass Report

• Elemental analysis providing accurate measurement of nitrogen and sulphur content. The results can be used to determine Net Peptide Content (NPC).

Additional Report

• A separate additional laboratory report issued under a different client name.

LC-MS Screening for Peptide Contamination

• LC-MS screening for contamination with other peptides or peptide degradation products. Detection is limited to peptides included in the available testing portfolio.
• The initial screening provides identification only. If contamination is detected, quantitative measurement may subsequently be ordered.

Sterility Testing

• TAMC and TYMC testing checks the product for the presence of bacteria, yeasts and moulds. Additional unopened sample units must be submitted for analysis. The average turnaround time for this test is 14 days.

Heavy Metals Analysis

• Detection of arsenic, cadmium, lead and mercury in the sample. Testing for other metals can be arranged individually.