L-Carnitine analysis

The L-Carnitine Analysis is a targeted laboratory test designed to confirm the identity and determine the amount of L-carnitine in oral dosage forms, liquid samples, and raw active pharmaceutical ingredient (API) powders.

The analysis is suitable for tablets and capsules, with results reported in milligrams per tablet or capsule, as well as liquid samples, with results reported in mg/ml. Raw API powders can be evaluated using an alternative result format based on purity in % (m/m).

About L-Carnitine

L-carnitine is a naturally occurring compound involved in mitochondrial fatty-acid metabolism. Its primary biological role is to transport long-chain fatty acids across the inner mitochondrial membrane, enabling their subsequent beta-oxidation and use as a source of cellular energy.

In the human body, L-carnitine is obtained from dietary sources and can also be synthesised endogenously from the amino acids lysine and methionine. It is concentrated particularly in tissues with high energy demands, such as skeletal and cardiac muscle, and is also used therapeutically in the management of primary and secondary carnitine deficiencies.

Key Features

• Targeted identification and quantification of L-carnitine
• Suitable for tablets, capsules, liquid samples, and raw API powders
• Analysis by HPLC
• Results for oral products reported in mg per tablet or capsule
• Results for liquid samples reported in mg/ml
• Alternative result format based on purity in % (m/m)
• Minimum sample amount of three tablets or capsules
• Minimum liquid sample amount of 0.5–1 ml
• Minimum sample amount of 200 mg for raw API powders
• Average turnaround time of 7 business days

Analysis Parameters

• Target compound: L-Carnitine
• CAS number: 541-15-1
• Testing method: HPLC
• Result format for oral products: mg per tablet or capsule
• Result format for liquid samples: mg/ml
• Alternative result format: Purity in % (m/m)
• Minimum sample amount for oral products: Three tablets or capsules
• Minimum sample amount for liquid samples: 0.5–1 ml
• Minimum sample amount for raw API powders: 200 mg
• Average turnaround time: 7 business days

Important Notice

• This analysis is specifically intended for L-carnitine. It does not automatically screen the sample for related carnitine derivatives, contaminants, or undeclared substances unless an additional screening service is ordered.
• Purity reporting in % (m/m) is available as an alternative result format.

Optional Additional Analyses

The following optional laboratory services are available:

• Complete Raw Analytical Data
• Fentanyl Screening
• Alternative Result Format: Purity in % (m/m)
• Batch Variance Testing
• pH Measurement
• LCMS Screening For Peptide Contamination
• Heavy Metals Analysis (As, Cd, Pb, Hg)
• Additional Laboratory Report