<p><strong>You may have the best HPLC system on the market, but to maximize your investment, you also need the best software to control the system and manage the data. If the software is complex to use, inflexible or lacking in functionality, it can greatly reduce your lab productivity, creating bottlenecks and inefficiencies. Furthermore, this can lead to unreliable results, increased error rates, cost implications and ultimately, a decrease in overall laboratory performance. By selecting the right Chromatography Data System (CDS) designed to meet current laboratory needs, you can eliminate errors and drive productivity with data that is accurate, trustworthy and secure.</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Elevate_Your_HPLC_Performance_with_a_Modern_CDS_cc757246f7.jpg" alt="Thermo Fisher Scientific: Elevate Your HPLC Performance with a Modern CDS." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Elevate_Your_HPLC_Performance_with_a_Modern_CDS_cc757246f7.jpg 245w," sizes="100vw" width="1024" height="512"></p><h3><strong>Be flexible and be in control</strong></h3><p>So, what if you have multiple HPLC’s from different vendors? <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/76"><strong>Thermo Scientific Chromeleon CDS</strong></a> offers full control over the widest range of HPLC and other chromatography instruments, including those from third-party manufacturers. This ensures you can maintain flexibility, while connecting and controlling your HPLC systems effortlessly. With features, such as auto-generated instrument panels that provide fast access to commands and live analysis plots, you can simplify navigation and enhance the overall user experience, making it easier to manage and monitor instruments.</p><h3><strong>Streamline your method development and validation</strong></h3><p>Support for your method development and validation needs is taken care of with <strong>predefined ICH method validation templates and built-in tools for method conversion, alongside integration with specialized software for automated and intelligent HPLC method development</strong>. This integration facilitates faster and more efficient method optimization and robustness testing, while the secure centralized data storage builds the perfect platform for compliance and future data review, providing a complete solution from method development to validation.</p><h3><strong>Robust compliance and secure data management</strong></h3><p><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/sp_70761_cds_ensure_compliance_sp70761_en_fd2abc669a.pdf"><strong>Compliance and security</strong></a> can be a crucial aspect of any HPLC operation, and Chromeleon CDS effectively addresses these needs. Your instrument management starts with fast integrated wizard-driven instrument qualification covering IQ, OQ and PQ with predefined templates and reports to optimize the instrument qualification process. The software employs a privilege-based approach to control access to both the instruments and the system, ensuring that only authorized and qualified personnel can interact with them. Dedicated instrument audit trails track all actions and will provide you with a full history that is searchable ensuring traceability, safeguarding the integrity of your data and operations.</p><h3><strong>Keep your instruments up and running</strong></h3><p>Productivity is only maintained if your HPLCs are operational and available for use. Integrated diagnostic tests offer insight into key information such as lamp operating hours or piston seal wear with warning limits for timely replacements. The <strong>active monitoring of service and qualification status</strong> allows for convenient maintenance scheduling and prevents unnecessary instrument downtime. An overview of diagnostic outcomes can also be produced as part of a routine health check ensuring that your HPLC instruments are always in optimal condition.</p><h3><strong>Get more right-first-time results</strong></h3><p>How can you prevent delays, time-consuming investigations, and ensure your analytical sequence runs correctly the first time? Chromeleon CDS offers you solutions to minimize user interaction, such as ready checks that automatically verify instrument configuration, methods, and sequences for issues, and automated system equilibration, which ensures the first injection is always good, eliminating the need for blank injections at the start of a sequence saving time and solvent. Automated shutdown procedures will manage a completed run, ensuring safe shutdown, system flushing, or maintaining a low flow rate to prevent component damage. Built-in system suitability tests with the ability to make in-run decisions, such as pause, stop or continue will maintain the integrity of your data and allow you to perform actions like re-injections and auto-dilutions for when samples are outside acceptable tolerance limits.<strong> Streamlining and automating the entire process of sequence creation is achieved through </strong><a target="_blank" rel="noopener noreferrer" href="https://documents.thermofisher.com/TFS-Assets/CMD/brochures/SP-70758-CDS-Chromeleon-Streamline-Workflow-SP70758-EN.pdf"><strong>eWorkflow procedures</strong></a>. These pre-defined templates contain all associated methods and reports, so your HPLC sequence can be automatically generated with just a few clicks, reducing errors, minimizing training, and producing reliable results faster.</p><h3><strong>A software designed to optimize HPLC lab efficiency</strong></h3><p>Chromeleon CDS is a no-compromise solution for your HPLC systems, designed to provide you with faster and better results through enhanced control, flexibility, diagnostics, right-first-time results, and compliance. Its user-friendly interface, comprehensive method development and validation tools, secure data management, and advanced diagnostics make it an indispensable tool for your HPLC laboratory. Find out more by downloading the case study: <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/cs_003880_hplc_vanquish_sanofi_optimize_manufacturing_drugs_cs003880_na_en_cf986bf4cc.pdf"><strong>Leveraging a Vanquish UHPLC system and Chromeleon CDS to optimize the manufacturing process</strong></a> or visiting <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/76"><strong>Chromatography Data System (CDS)</strong></a>.</p><p><strong>Visit us on&nbsp;</strong><a target="_blank" rel="noopener noreferrer" href="https://www.linkedin.com/showcase/72003132/admin/dashboard/"><strong><u>LinkedIn:</u></strong></a><strong>&nbsp;#Chromeleon #ChromatographyDataSystem #HPLC #UHPLC</strong></p><section><blockquote><h5><strong>Peter Zipfell</strong></h5><p>For over 25 years, he has worked extensively with analytical hardware and software transitioning from LC-MS method development through HPLC technical support to chromatography data systems. His focus has always been to support our customers by delivering software solutions across multiple industries to enable them to improve their current workflows and increase productivity.</p></blockquote></section>

Elevate Your HPLC Performance with a Modern CDS

<h3><a target="_blank" rel="noopener noreferrer" href="https://www.isc2026.org/"><strong>ISC 2026</strong></a></h3><p>The <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/314"><strong>International Symposium on Chromatography (ISC)</strong></a> represents the oldest conference series on separation science. ISC symposia have been organised since 1956 in each even year. ISC is one of the premier meetings series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.</p><p>The major focus of the symposium will be on the impact of chromatography and separation science to meet the needs of the pharmaceutical, environmental, food and health industry, as well as science and medicine. The symposium programme will reflect these themes and highlight new challenges and emerging opportunities for the science and marketing of separation and detection systems and methods.</p><p>As an integral part of the scientific programme of lectures and poster sessions, an international exhibition and vendor seminars on instrumentation and services for chromatography, separation science and mass spectrometry will be organised. ISC 2026 will provide the perfect forum for attendees from academia, industry and government research institutions for scientific exchange and networking.</p><h3><strong>ISC 2026 SYMPOSIUM KEY DATES</strong></h3><h4><strong>6-10 SEPTEMBER 2026</strong></h4><ul><li><strong>15 January 2026:</strong> Opening of Early-bird Registration &amp; Abstract submission</li><li><strong>11 March 2026: </strong>Deadline for abstract submission (orals)</li><li><strong>21 April 2026: </strong>Sending acceptance letters (orals)</li><li><strong>15 May 2026: </strong>Deadline of early-bird registration and payment &amp; Author registration deadline (orals)</li><li><strong>1 June 2026: </strong>Preliminary detailed program on web</li><li><strong>1 June 2026: </strong>Deadline for abstract submission (posters)</li><li><strong>16 June 2026: </strong>Sending acceptance letters (posters)<ul><li>Authors who submit their abstracts with a poster preference by 5 May 2026 will be notified of the outcome by 12 May 2026 and will have the opportunity to register at the early-bird rate until 15 May 2026.</li></ul></li><li><strong>30 June 2026:</strong> Author registration deadline (posters)</li><li><strong>30 July 2026:</strong> Deadline for abstract submission (late-breaking posters)<ul><li>without the possibility of competing for the Best Poster Award</li></ul></li><li><strong>11 August 2026: </strong>Sending acceptance letters (late-breaking posters)</li><li><strong>18 August 2026:</strong> Author registration deadline (late-breaking posters)</li><li><strong>25 August 2026: </strong>Deadline for late registration &amp; payment&nbsp;</li><li><strong>6-10 September 2026: </strong>Symposium</li></ul><h3><strong>REGISTRATION</strong></h3><blockquote><p><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://www.czech-in.org/cmPortalV15/Account/Login?ReturnUrl=%2FcmPortalV15%2FPortal%2FISC26%2Fnormal"><strong>Register HERE for the ISC 2026</strong></a></p></blockquote><h3><strong>ABSTRACT SUBMISSION</strong></h3><blockquote><p><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://www.czech-in.org/cmPortalV15/Account/Login?ReturnUrl=%2FcmPortalV15%2FPortal%2FISC26%2Fnormal"><strong>Submit your Abstract HERE</strong></a></p></blockquote><h3><strong>SCIENTIFIC PROGRAM</strong></h3><h4><strong>SHORT COURSES</strong></h4><h5><strong>SC 3 Interpretation of Mass Spectra: Basic Introduction for Chromatographers</strong></h5><p><strong>🗓️ SUNDAY, 6 SEPTEMBER 2026</strong></p><p><strong>🕗 8:30 – 11:45</strong></p><p>Mass spectrometry has become an essential tool in modern liquid chromatography, yet many chromatographers receive limited formal training in mass-spectral interpretation. This introductory short course provides a practical guide to understanding and interpreting mass spectra generated by the atmospheric-pressure ionization techniques coupled with LC: electrospray ionization (ESI), atmospheric-pressure chemical ionization (APCI), and atmospheric-pressure photoionization (APPI). The course begins by outlining the information that mass spectrometry adds beyond a chromatogram and clarifying which analytical questions mass spectrometry can – and cannot – answer. Participants receive a concise refresher on mass-spectrometric fundamentals, along with an introduction to key terminology. The principles and practical consequences of ionization methods are then discussed, with emphasis on how ionization physics, LC conditions, and mobile-phase additives shape spectral appearance. Building on this foundation, the course develops practical skills for interpreting LC-ESI spectra: locating the molecular ion, determining charge state, recognizing common adducts, distinguishing in-source artefacts, and using isotope patterns to support elemental-composition hypotheses. Participants then explore how MS/MS fragmentation provides structural clues, with straightforward rules of thumb for neutral losses and class-specific fragmentation behaviors. The course concludes with an integrative exercise that synthesizes chromatographic, full-scan, and MS/MS information to support spectral interpretation. By the end, participants will be equipped with the essential skills needed to interpret LC-MS spectra effectively and to apply mass-spectrometric reasoning in routine chromatographic analysis.&nbsp;</p><h4><strong>Lecturers</strong></h4><h5><strong>Josef Cvačka</strong></h5><ul><li>Josef Cvačka is head of the Mass Spectrometry Group at the Institute of <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/62"><strong>Organic Chemistry and Biochemistry of the Czech Academy of Sciences</strong></a> and an associate professor at the Faculty of Science, Charles University in Prague. His research focuses on the structural analysis of bioactive organic compounds using advanced mass-spectrometric techniques. He develops methods for pinpointing double-bond and methyl-branching positions in lipids and aims to discover new lipid classes in biological samples. His laboratory also designs new ion sources for MS and HPLC/MS. He teaches and supervises students at Charles University and founded the <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/articles?search=Czech+Museum+of+Mass+Spectrometry"><strong>Czech Museum of Mass Spectrometry</strong></a>.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Josef_Cvacka_5cc8a0d1d4.jpg" alt="ISC 2026: Josef Cvačka" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Josef_Cvacka_5cc8a0d1d4.jpg 156w," sizes="100vw" width="510" height="510"></p>

ISC 2026 Short Course 3 - Interpretation of Mass Spectra: Basic Introduction for Chromatographers

<p><strong>Eurachem and CITAC welcome analysts interested in the evaluation of chemical analysis uncertainty and in how to use this information in results interpretation. The Eurachem Week 2026 will begin with a training course on “Evaluation of the measurement uncertainty from in-house precision and recovery data” scheduled for Sunday, 10 May 2026. A two-days workshop on “Quality in Analytical Measurements: Uncertainty Evaluation and Results Interpretation” open to all interested participants will take place from 11 to 12 May 2026. On 13 May 2026, the Eurachem Working Groups will convene, followed by the Eurachem General Assembly, which will bring together the Executive and national delegates on 14 and 15 May. Both Working Group Meetings and the General Assembly are restricted to their members.</strong></p><p>The results of qualitative and quantitative chemical analyses should have an acceptable uncertainty, which should ideally be reported and considered in results interpretation.</p><p>For many analytical applications, simplified uncertainty evaluations can determine uncertainty values that meet the defined requirements for this parameter. The workshop will focus on the key technical challenges involved in practical evaluations of measurement uncertainty based on precision and recovery data gathered during in-house method validation and quality control. There will be a discussion of how to model the variation of the measurement uncertainty within the analytical range and how to handle divergent recovery values from the analysis of various reference materials. A session on the use of measurement uncertainty in conformity assessment will explore how the risk of false conformity decisions can be managed.</p><blockquote><h5><strong>New Eurachem guidance on using in-house precision and recovery data will be discussed at the workshop.</strong></h5></blockquote><p>Topics will also include the validation and uncertainty evaluation for qualitative analyses with particular attention to current accreditation requirements for these types of analysis. The last session of the workshop will be dedicated to the evaluation of measurement uncertainty arising from sampling and using it to judge the fitness for purpose, and hence validation, of measurement procedures that include sampling. Four sessions of the workshop will include engaging breakout sessions where participants will have the chance to share their views about challenging aspects of the analytical work. Participants are invited to propose posters and oral communications on session topics or any other relevant topic for analytical chemists or stakeholders of the analytical work.</p><h3><strong>Registration</strong></h3><blockquote><p class="cke-user_style-important"><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://conferences.chemistry.pt/register/eurachem2026"><strong>Register here for the workshop</strong></a></p></blockquote><h4><strong>Registration Fees</strong></h4><h5><strong>Early bird (EUR) - Until April 15th</strong></h5><ul><li><strong>Workshop: Regular participant (11 &amp; 12 May 2026): </strong>400 EUR</li><li><strong>Workshop: Student (11 &amp; 12 May 2026): </strong>250 EUR</li><li><strong>Eurachem Working Group<sup>1</sup> (13 May 2026):</strong> 75</li><li><strong>General Assembly<sup>2</sup> (14 &amp; 15 May 2026): </strong>250</li><li><strong>Training On Uncertainty Evaluation<sup>3</sup> (10 May 2026):</strong> 150</li></ul><h5><strong>After April 15th</strong></h5><ul><li><strong>Workshop: Regular participant (11 &amp; 12 May 2026): </strong>450 EUR</li><li><strong>Workshop: Student (11 &amp; 12 May 2026):</strong> 300 EUR</li><li><strong>Eurachem Working Group<sup>1</sup> (13 May 2026): </strong>100</li><li><strong>General Assembly<sup>2</sup> (14 &amp; 15 May 2026):</strong> 300</li><li><strong>Training On Uncertainty Evaluation<sup>3</sup> (10 May 2026): </strong>200</li></ul><blockquote><p>§ - <strong>50 EUR reduction for members of Eurachem</strong>, CITAC, SPQ, RELACRE, ForMEQ and SPMet at the workshop.</p><p>10% reduction for organisations that registered more than one participant.</p><p><sup>1 </sup>- Working group members</p><p><sup>2</sup> - Eurachem members</p><p><sup>3</sup> - 50% reduction for workshop participants</p></blockquote><h3><strong>Workshop</strong></h3><h4><strong>Eurachem/CITAC Workshop on Quality in Analytical Measurements:</strong></h4><h5><strong>Uncertainty Evaluation and Results Interpretation</strong></h5><p>The results of qualitative and quantitative chemical analyses should have an acceptable uncertainty, which should ideally be reported and considered in results interpretation. For many analytical applications, simplified uncertainty evaluations can determine uncertainty values meeting defined requirements for this parameter. The workshop will focus on the key technical challenges involved in practical evaluations of measurement uncertainty based on precision and recovery data gathered during in-house method validation. It will be discussed how to model the variation of the measurement uncertainty within the analytical range and how to handle divergent recovery values from the analysis of various reference materials. A session on the use of measurement uncertainty in conformity assessment will explore how the risk of false conformity decisions can be managed.</p><p>Topics will also include the validation and uncertainty evaluation of qualitative analyses with particular attention to current accreditation requirements for these types of analysis. The last session of the workshop will be dedicated to the evaluation of measurement uncertainty arising from sampling and using it to judge the fitness for purpose, and hence validation, of measurement procedures that include sampling.</p><p>Four sessions of the workshop will include engaging breakout sessions where participants will have the chance to share their views about challenging aspects of the analytical work. Participants are invited to propose posters and oral communications on session topics or any other relevant topic for analytical chemists or stakeholders of the analytical work.</p><h3><strong>Training Course</strong></h3><h4><strong>Evaluation of the measurement uncertainty from in-house precision and recovery data</strong></h4><ul><li>10 May 2026</li></ul><p>A course on the fundamentals of the evaluation of the measurement uncertainty from in-house precision and recovery data will be held on Sunday, 10 May 2026. This training is targeted for analysts with a basic understanding of the measurement uncertainty concept, how uncertainty components propagate, and how the combined uncertainty is expanded. Following the morning presentation of the theory of uncertainty evaluation, the afternoon will be dedicated to applying the theory to real-world cases. Trainees should have basic skills in using Microsoft Excel spreadsheets and bring a laptop with Microsoft Excel to complete the exercises. The interaction between trainers and trainees will be promoted to guarantee learning efficiency.</p><h5><strong>Trainers:</strong></h5><ul><li>Ricardo Bettencourt da Silva, Faculdade de Ciências da Universidade de Lisboa, Portugal (rjsilva@ciencias.ulisboa.pt)</li><li>Stephen L. R. Ellison - UK National Measurement Laboratory (NML) hosted at LGC, United Kingdom</li><li>Vicki Barwick - UK National Measurement Laboratory (NML) hosted at LGC, United Kingdom</li></ul><h4><strong>Agenda</strong></h4><h5><strong>8:00 Registration</strong></h5><h5><strong>9:00 Opening</strong></h5><h5><strong>9:05 Identifying, combining, and expanding uncertainty components: Theory and examples</strong></h5><h5><strong>9:45 Precision uncertainty: Theory and examples</strong></h5><h5><strong>10:30 </strong>Coffee break</h5><h5><strong>10:50 Trueness-related uncertainty: Theory and examples</strong></h5><h5><strong>12:00 Additional questions and discussion</strong></h5><h5><strong>12:30 </strong>Lunch</h5><h5><strong>13:30 Application example 1</strong></h5><h5><strong>15:30 </strong>Coffee break</h5><h5><strong>15:50 Application example 2</strong></h5><h5><strong>17:00 Additional questions and discussion</strong></h5><h5><strong>17:30 Closing</strong></h5><h3><strong>Venue</strong></h3><p>The series of Eurachem events will be held in:</p><ul><li>Meliã Lisboa Aeroporto ****</li><li>Rua C,2 1749-125 Lisboa, Portugal&nbsp;</li></ul>

Eurachem/CITAC Workshop on Quality in Analytical Measurements 2026

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Eurachem is a European network promoting international traceability of chemical measurements and good analytical practice. It provides expert guidance, supports method validation, uncertainty evaluation, proficiency testing, and facilitates discussion on technical and policy issues in analytical quality.

Eurachem

The International Symposium on Chromatography (ISC) represents the oldest conference series focussing on separation science. ISC symposia have been organised since 1956 in each even year. ISC is internationally recognised as one of the premier meeting series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.

International Symposium on Chromatography - (ISC)

Thermo Scientific Dionex IonPac CS16-4μm and CS16-Fast-4μm IC Columns

Resolve ammonium and sodium at ratios up to 10,000:1 with CS16-4μm columns. Faster, high-resolution cation analysis without pretreatment—even in complex matrices.

<p><strong>Analyze disparate concentration ratios up to 10,000:1 of close-eluting cations such as ammonium and sodium using Thermo Scientific™ Dionex™ IonPac™ CS16-4μm and CS16-Fast-4μm columns. Designed specifically for the analysis of cations at diverse concentration ratios, this high-capacity column combines the selectivity of the Dionex IonPac CS16 column with fast, high resolution separations. Compared to the Dionex IonPac CS16 column, the new Dionex IonPac CS16-4μm and CS16-Fast-4μm columns use smaller resin particles for more efficient separations resulting in faster run times, more accurate peak integration, and more reliable results.</strong></p><h5><strong>Highest Resolution Separation of Ammonium and Sodium at Disparate Concentration Ratios up to 10,000:1 in Diverse Matrices</strong></h5><ul><li>Recommended for trace-level ammonium in high concentrations of sodium without sample pretreatment</li><li>Recommended for trace-level sodium in high concentrations of ammonium without sample pretreatment</li><li>Use the 250 mm Dionex IonPac CS16-4μm for complex matrices</li><li>Use the 150 mm Dionex IonPac CS16-Fast-4μm for faster analyses in simple matrices.</li><li>Easily transfer applications from the Dionex IonPac CS16 column to the 4 μm columns due to the similar selectivity</li><li>High capacity facilitates injection of more concentrated samples without column overloading or peak broadening</li><li>Compatible with organic solvents, excluding alcohols, to enhance analyte solubility, modify column selectivity, and facilitate effective column clean-up</li></ul><h5><strong>Use with a High-Pressure IC System</strong></h5><p>Higher resolution is achieved through the use of smaller resin particles, which produce a column backpressure over 3000 psi at the standard flow rates. A high-pressure IC system, such as the <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/410"><strong>Thermo Scientific™ Dionex™ ICS-6000+ HPIC™ system</strong></a>, is required to operate this column under standard conditions and take advantage of elevated flow rates and faster run times.</p><h6><strong>Reduce Operating Costs With Lower Eluent Requirements</strong></h6><p>The Dionex IonPac CS16-4μm capillary columns provide the same performance as the standard bore and microbore Dionex IonPac CS16-4μm columns because they are packed with the same material. Operating costs are reduced because the capillary system operates at only 1% of the eluent flow rate of the standard bore system, requiring less eluent and producing less waste.</p><h5><strong>Multiple Formats Available for Application Flexibility</strong></h5><ul><li>Dionex IonPac CS16-4μm: Available in 4 mm, 2 mm, and 0.4 mm formats</li><li>Dionex IonPac CS16-Fast-4μm: Available in 4 mm and 2 mm formats</li><li>Longer 250 mm columns facilitate higher resolution separations of more complex sample matrices</li><li>Shorter 150 mm columns provide faster analyses of simple matrices</li><li>Smaller i.d. columns provide higher mass sensitivity, eluent and reagent conservation and lower operating costs</li></ul><h4><strong>Specifications</strong></h4><ul><li><strong>Crosslinking: </strong>55% DVB</li><li><strong>Column Capacity:</strong> 3220 μeq</li><li><strong>For Use With (Application):</strong> Cation Exchange</li><li><strong>Max. Pressure:</strong> 5000 psi (345 bar)</li><li><strong>Solvent Compatibility:</strong> Acidic Eluents (pH 0 to 7), 0 to 100% Acetonitrile, 0 to 100% Acetone, Alcohols Should be Avoided</li><li><strong>Stationary phase:</strong> IonPac CS16-4μm</li><li><strong>Format:</strong> Standard Bore</li><li><strong>Packing Material: </strong>Ethylvinylbenzene/Divinylbenzene</li></ul>

Thermo Scientific Dionex IonPac CS17 IC Columns

Obtain excellent selectivity and peak shapes for hydrophobic amines in complex matrices without solvent using the Thermo Scientific Dionex IonPac CS17 column.

<p><strong>Obtain excellent selectivity and peak shapes for hydrophobic amines in complex matrices without solvent using the Thermo Scientific™ Dionex™ IonPac™ CS17 column. This medium-capacity, carboxylate-functionalized column is optimized for the gradient separation of hydrophobic and polyvalent amines using simple aqueous eluents and elevated temperatures (40°C). It is intended for analysis of power plant waters treated with ammonium, morpholine, or ethanolamine; chemical additives; chemical process solutions; scrubber solutions; plating baths; industrial solvents; and food samples.</strong></p><h5><strong>Gradient Separation of Common Cations and Small Polar Amines in Diverse Matrices</strong></h5><ul><li>Hydrophilic, low-capacity column optimized for gradient separation of polyvalent and hydrophobic amines–including alkanolamines and methylamines–in complex sample matrices</li><li>Separation of moderately hydrophobic amines, including biogenic amines, alkyldiamines, and polyamines.</li><li>Minimal baseline shift and enhanced analyte sensitivity</li><li>Improved peak shape for most Thermo Scientific™ Dionex™ IonPac™ CS14, CS15, and CS16 column amine applications without the use of solvent</li><li>Optimized for simple acidic gradient applications</li><li>Compatibility with organic solvents to enhance analyte solubility, modify column selectivity, and facilitate effective column clean-up</li></ul><h5><strong>Multiple Formats Available for Application Flexibility</strong></h5><ul><li>4x250mm, 2x250mm analytical columns</li><li>4x50mm, 2x50mm guard columns</li><li>Longer 250mm columns facilitate higher resolution separations of more complex sample matrices</li><li>Smaller i.d. columns provide higher mass sensitivity, eluent and reagent conservation and lower operating costs.</li></ul><h4><strong>Specifications</strong></h4><ul><li><strong>Crosslinking: </strong>55% DVB</li><li><strong>Column Capacity:</strong> 1450 μeq</li><li><strong>For Use With (Application):</strong> Cation Exchange</li><li><strong>Max. Pressure:</strong> 4000 psi (275 bar)</li><li><strong>Solvent Compatibility:</strong> Acidic Eluents, 0 to 100% HPLC Solvents, Including Alcohols</li><li><strong>Stationary phase:</strong> IonPac CS17</li><li><strong>Format:</strong> Standard Bore</li><li><strong>Packing Material: </strong>Ethylvinylbenzene/Divinylbenzene</li></ul>

Thermo Scientific Dionex IonPac CS18 IC Columns

Separate polar amines with the Thermo Scientific™ Dionex™ IonPac™ CS18 Cation-Exchange Column. 

<p><strong>Separate polar amines with the Thermo Scientific™ Dionex™ IonPac™ CS18 Cation-Exchange Column. This low-capacity, carboxylate-functionalized column is specifically optimized for the separation of common cations, small polar amines, and moderately hydrophobic and polyvalent anions using simple aqueous eluents and elevated temperatures. However, the newer Thermo Scientific™ Dionex™ IonPac™ CS19 or Dionex IonPac CS19-4μm Cation Exchange Columns are the recommended columns for these applications.</strong></p><h5><strong>Cation and Amine Separations Using Suppressed and Non-suppressed Conductivity Detection</strong></h5><ul><li>Low-capacity column optimized for the isocratic and gradient separations of polar amines, moderately hydrophobic amines, and polyvalent cations</li><li>Can be used with suppressed and nonsuppressed conductivity detection</li><li>Nonsuppressed conductivity detection is recommended to extend calibration linearity for ammonium or weak bases</li><li>Can also be used for many of the nonsuppressed applications supported by the Dionex IonPac SCS-1 column but with much greater column stability</li><li>Optimized for simple acidic gradient separations with minimal baseline shift</li><li>Low capacity facilitates modest acid concentrations to elute polyvalent cations</li><li>Compatible with moderate amounts of organic solvents, excluding alcohols, to enhance analyte solubility, modify column selectivity, and facilitate effective column clean-up</li></ul><h5><strong>Formats Available for Application Flexibility</strong></h5><ul><li>2x250mm analytical columns</li><li>2x50mm guard columns</li><li>Longer 250mm columns facilitate higher resolution separations of more complex sample matrices</li><li>Smaller i.d. columns provide higher mass sensitivity, eluent and reagent conservation and lower operating costs</li></ul><h4><strong>Specifications</strong></h4><ul><li><strong>Crosslinking: </strong>55% DVB</li><li><strong>Column Capacity:</strong> 290 μeq</li><li><strong>For Use With (Application):</strong> Cation Exchange</li><li><strong>Max. Pressure:</strong> 4000 psi (275 bar)</li><li><strong>Solvent Compatibility:</strong> Acidic Eluents (pH 0 to 7), 0 to 20% HPLC Solvents, Alcohols Should be Avoided</li><li><strong>Stationary phase:</strong> IonPac CS18</li><li><strong>Format:</strong> Microbore</li><li><strong>Packing Material: </strong>Ethylvinylbenzene/Divinylbenzene</li></ul>

Thermo Scientific Dionex IonPac CS19 IC Columns

Separate common inorganic cations, small polar amines and polyvalent amines using Thermo Scientific Dionex IonPac CS19 IC Columns

<p><strong>Separate polar amines with the Thermo Scientific™ Dionex™ IonPac™ CS19 Cation-Exchange Column. This high-capacity, carboxylate-functionalized column is specifically optimized for the separation of common cations, small polar amines, and moderately hydrophobic and polyvalent cations using simple aqueous eluents and elevated temperatures. The column is ideal for analysis of power plant waters treated with ammonium, morpholine, or ethanolamine and can also be used to analyze chemical additives, chemical process solutions, scrubber solutions, personal care products, and food samples.</strong></p><h5><strong>Analyze Common Cations and Small Polar Amines in Diverse Matrices</strong></h5><ul><li>Simple gradient separation of small polar amines (including alkanolamines and methylamines), and moderately hydrophobic and polyvalent amines (including biogenic amines and alkyl diamines)</li><li>Optimized for simple acidic gradient separations with minimal baseline shift</li><li>High capacity facilitates the analysis of widely disparate peak pairs and high ionic strength matrices with less overloading of the column</li><li>Compatible with moderate amounts of organic solvents, excluding alcohols, to enhance analyte solubility, modify column selectivity, and facilitate effective column clean-up</li></ul><h5><strong>Multiple Formats Available for Application Flexibility</strong></h5><ul><li>4x250mm, 2x250mm analytical columns</li><li>4x50mm, 2x50mm guard columns</li><li>Longer 250mm columns facilitate higher resolution separations of more complex sample matrices</li><li>Smaller i.d. columns provide higher mass sensitivity, eluent and reagent conservation and lower operating costs</li></ul><h4><strong>Specifications</strong></h4><ul><li><strong>Crosslinking: </strong>55% DVB</li><li><strong>Column Capacity:</strong> 2410 μeq</li><li><strong>For Use With (Application):</strong> Cation Exchange</li><li><strong>Max. Pressure:</strong> 3000 psi (207 bar)</li><li><strong>Solvent Compatibility:</strong> Acidic Eluents (pH 0 to 7), 0 to 10% HPLC Solvents, Alcohols Should be Avoided</li><li><strong>Stationary phase:</strong> Super Macroporous Resin</li><li><strong>Format:</strong> Standard Bore</li><li><strong>Packing Material: </strong>Ethylvinylbenzene/Divinylbenzene</li></ul>

Thermo Scientific Dionex IonPac CS19-4μm IC Columns

High-capacity ion-exchange column with 4 μm resin for highest resolution of cations and polar amines in complex samples. Enables fast, reliable separations and cost-effective operation with HPIC systems.

<p><strong>Attain the optimal combination of chromatographic speed and high resolution using the new Thermo Scientific™ Dionex™ IonPac™ CS19-4μm Capillary, Analytical, &amp; Guard Column. This high-capacity, high-resolution carboxylate-functionalized column provides excellent resolution of common cations, small polar amines, and polyvalent amines in complex sample matrices such as power plant waters treated with ammonium, morpholine, or ethanolamine, chemical additives, chemical process solutions, scrubber solutions, personal care products, and food samples.</strong><br><strong>Compared to the Thermo Scientific™ Dionex™ IonPac™ CS19 column, this column uses smaller resin particles for more efficient separations resulting in more accurate peak integration and more reliable results.</strong></p><h5><strong>Highest Resolution Separation of Common Cations and Small Polar Amines in Diverse Matrices</strong></h5><ul><li>Highest resolution, through the use of smaller resin particles, of common cations and small polar amines in complex sample matrices</li><li>Higher peak efficiency and increased peak resolution for more consistent integration and more reliable results</li><li>Easily transfer applications from the Dionex IonPac CS19 column to the 4 μm column due to the similar selectivity</li><li>Simple gradient separation of small polar amines (including alkanolamines and methylamines), and moderately hydrophobic and polyvalent amines (including biogenic amines and alkyl diamines)</li><li>High capacity facilitates injection of more concentrated samples without column overloading or peak broadening</li><li>Compatible with moderate amounts of organic solvents, excluding alcohols, to enhance analyte solubility, modify column selectivity, and facilitate effective column clean-up</li></ul><h5><strong>Use With a High-Pressure IC System</strong></h5><p>Higher resolution is achieved through the use of smaller resin particles, which produce a column backpressure over 3000 psi at the standard flow rates. A high-pressure IC system, such as the Thermo Scientific™ Dionex™ ICS-5000+ HPIC™ or the Dionex ICS-4000 Capillary HPIC system is required to operate this column under standard conditions and take advantage of elevated flow rates and faster run times.</p><h5><strong>Reduce Operating Costs With Lower Eluent Requirements</strong></h5><p>The Dionex IonPac CS19-4μm capillary column provides the same performance as the standard bore and microbore Dionex IonPac CS19-4μm columns because it is packed with the same material. Operating costs are reduced because the capillary system operates at only 1% of the eluent flow rate of the standard bore system, requiring less eluent and producing less waste.</p><h5><strong>Multiple Formats Available for Application Flexibility</strong></h5><ul><li>4x250mm, 2x250mm analytical columns</li><li>4x50mm, 2x50mm guard columns</li><li>0.4x250mm capillary column, 0.4x50mm capillary guard column</li><li>Longer 250mm columns facilitate higher resolution separations of more complex sample matrices</li><li>Smaller i.d. columns provide higher mass sensitivity, eluent and reagent conservation and lower operating costs</li></ul><h4><strong>Specifications</strong></h4><ul><li><strong>Crosslinking: </strong>55% DVB</li><li><strong>Column Capacity:</strong> 2410 μeq</li><li><strong>For Use With (Application):</strong> Cation Exchange</li><li><strong>Max. Pressure:</strong> 5000 psi (345 bar)</li><li><strong>Solvent Compatibility:</strong> Acidic Eluents (pH 0 to 7), 10% HPLC Solvents, Alcohols Should be Avoided</li><li><strong>Stationary phase:</strong> IonPac CS19-4μm</li><li><strong>Format:</strong> Standard Bore</li></ul>

Thermo Scientific Dionex IonPac CS20 IC Columns

Analyze inorganic cations and amines using the Thermo Scientific™ Dionex™ IonPac™ CS20 ion chromatography (IC) columns.

<p><strong>Analyze inorganic cations and amines using the Thermo Scientific™ Dionex™ IonPac™ CS20 ion chromatography (IC) columns. Designed to complement Dionex IonPac CS18 and Dionex IonPac CS19 columns, the Dionex IonPac CS20 columns provide a large separation window between monovalent and divalent cations. This allows most amines to elute after the alkali metals but before the alkaline earth metals, moving the amines away from matrix ions that would normally make quantitation difficult. Its selectivity makes the Dionex IonPac CS20 particularly useful for determining a variety of alkyl and alkanol amines.</strong></p><h5><strong>Superior performance in the separation of common inorganic cations and amines</strong></h5><ul><li>Use the high capacity Dionex IonPac CS20 to determine inorganic cations and amines including methylamines, ethylamines, ethanolamines, and alkanolamines in diverse sample matrices</li><li>Unique stationary phase functionalized with a combination of sulfonic, phosphonic, and carboxylic acid groups can tolerate acidic samples containing up to 100mM hydronium ion (pH 1) with minimum loss of performance</li><li>Operable over a wide temperature range (15-70°C) to facilitate method development and improve critical pair separations</li><li>Compatible with 100% organic solvents (acetonitrile and acetone) to enhance analyte solubility, modify column selectivity, and facilitate effective column clean-up</li></ul><h5><strong>Use with a high-pressure IC system</strong></h5><p>A high-pressure IC system, such as the Thermo Scientific™ Dionex™ ICS-5000+ HPIC™, Dionex Integrion™ HPIC system, or the Dionex ICS-4000 Capillary HPIC system is required to operate this column under standard conditions.</p><h5><strong>Reduce operating costs with lower eluent requirements</strong></h5><p>The Dionex IonPac CS20 capillary columns provide the same performance as the standard bore and microbore Dionex IonPac CS20 columns because they are packed with the same material. Operating costs are reduced because the capillary system operates at only 1% of the eluent flow rate of the standard bore system, requiring less eluent and producing less waste.</p><h5><strong>Multiple Formats Available</strong></h5><ul><li>4x250mm and 2x250mm analytical columns</li><li>4x50mm and 2x50mm analytical guard columns</li><li>0.4x250mm capillary columns</li><li>0.4x50mm capillary guard columns</li><li>Smaller i.d. columns provide higher mass sensitivity, conserve eluent and reagents, and reduce operating costs</li></ul><h4><strong>Specifications</strong></h4><ul><li><strong>Crosslinking: </strong>55% DVB</li><li><strong>Column Capacity:</strong> 3000 μeq</li><li><strong>For Use With (Application):</strong> Cation Exchange</li><li><strong>Max. Pressure:</strong> 5000 psi (345 bar)</li><li><strong>Solvent Compatibility:</strong> pH 0 to 7, 0 to 100% Organic HPLC Solvents, Alcohols Should be Avoided</li><li><strong>Stationary phase:</strong> Macroporous Resin</li><li><strong>Format:</strong> Standard Bore</li><li><strong>Packing Material: </strong>Ethylvinylbenzene/Divinylbenzene</li></ul>

Thermo Scientific Dionex IonPac CS21-Fast-4μm IC Columns

Resolve quaternary amine cationic polar pesticides including chlormequat, mepiquat, paraquat, and diquat with the Thermo Scientific™ Dionex™ IonPac™ CS21-Fast-4μm column. 

<p><strong>Resolve quaternary amine cationic polar pesticides including chlormequat, mepiquat, paraquat, and diquat with the Thermo Scientific™ Dionex™ IonPac™ CS21-Fast-4μm column. The unique selectivity of the Dionex IonPac CS21-Fast-4μm column allows it to resolve trace amounts of cationic polar pesticides in high ionic strength matrices within approximately fifteen minutes using an electrolytically generated MSA gradient. Quaternary amines are eluted away from matrix cations, making the Dionex IonPac CS21-Fast-4μm column ideal for IC-MS/MS applications where matrix ions are diverted to waste.</strong></p><h5><strong>Superior Chromatographic Performance</strong></h5><ul><li>High capacity allows injection of complex matrices without overloading the column while maintaining excellent peak shapes for lower concentration analytes.</li><li>Quickly separate trace levels of the four major quaternary amine cationic polar pesticides chlormequat, mepiquat, paraquat, and diquat in high ionic strength matrices using an MSA gradient.</li><li>Separate other cationic pesticides of interest including diethanolamine, triethanolamine, N-N-dimethylhydrazine, trimethylsulfonium, morpholine, melamine, streptomycin, and nereistoxin.</li></ul><h5><strong>Specifically designed for IC-MS/MS applications</strong></h5><ul><li>Completely resolves paraquat and diquat, species with similar masses.</li><li>Available in microbore format that is compatible with MS flow rates.</li><li>Selectivity allows matrix ions to be diverted to waste which keeps the MS source cleaner.</li><li>Solvent compatible (up to 100% acetonitrile and 20% isopropyl alcohol).</li><li>Fast analysis of cationic polar pesticides in food, beverages, and environmental waters.</li></ul><h5><strong>Use with a High-Pressure IC system</strong></h5><p>A high-pressure IC system, such as the <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/410"><strong>Thermo Scientific™ Dionex™ ICS-6000 HPIC system</strong></a> or <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/408"><strong>Thermo Scientific™ Dionex™ Integrion™ HPIC system</strong></a> is required to operate this column under standard conditions.</p><h4><strong>Specifications</strong></h4><ul><li><strong>Crosslinking: </strong>80% DVB</li><li><strong>Column Capacity:</strong> 110 μeq</li><li><strong>For Use With (Application):</strong> Cation Exchange</li><li><strong>Max. Pressure:</strong> 5000 psi (345 bar)</li><li><strong>Solvent Compatibility:</strong> pH 0-7, HPLC solvents (100% acetonitrile and up to 20% isopropyl alcohol), primary and secondary alcohols should be avoided)</li><li><strong>Format:</strong> Microbore</li><li><strong>Packing Material:</strong> Ethylvinylbenzene/Divinylbenzene</li></ul>

Thermo Scientific SurePac Bio 550 SEC MDi HPLC Columns

SurePac™ Bio 550 SEC MDi™ column delivers high-resolution, reproducible AAV size-based separations with 3 μm silica, 550 Å pores, and bioinert hardware for optimal recovery and QC reliability.

<p><strong>Experience the future of Size-Exclusion Chromatography (SEC) with SurePac™ Bio 550 SEC MDi™ analytical columns and guards exclusively designed to deliver robust and reproducible performance at high resolution and throughput to accelerate your therapeutics analysis process. The column's groundbreaking MDi™ technology integrates our advanced 3 μm monodisperse silica particle platform with bioinert hardware to ensure superior reliability for best sample recovery. SurePac™ Bio 550 SEC MDi™ column is ideal for AAV gene therapeutics analysis and offers excellent selectivity due to the dedicated smaller particle (3 μm) size combined with wide-pore (550Å) for separating monomeric AAVs from aggregates based on their size differences.</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Sure_Pac_Bio_550_SEC_M_Di_HPLC_Columns_3_8391a584e0.jpg" alt="Thermo Scientific: SEM image of 3μm monodisperse silica particles (left) vs. 3 μm polydisperse particles (right)" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Sure_Pac_Bio_550_SEC_M_Di_HPLC_Columns_3_8391a584e0.jpg 245w," sizes="100vw" width="1023" height="508"></p><p>SurePac Bio 550 SEC MDi columns and guards are based on high-purity, spherical, porous (550 Å), 3 μm monodispersed silica particles that are covalently modified with a proprietary diol hydrophilic layer. This unique design yields shorter diffusion distances and enhanced reproducible mass transfer and narrower peaks. The consistent size of these particles facilitates precise control over media synthesis and column packing, significantly improving column-to-column and lot-to-lot reproducibility. The columns are housed in a hydrophilic bioinert-coated stainless-steel hardware to eliminate secondary interactions, ensuring optimal performance during the initial injection process.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Sure_Pac_Bio_550_SEC_M_Di_HPLC_Columns_043f131056.jpg" alt="Thermo Scientific: SurePac Bio 550 SEC MDi HPLC Columns" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Sure_Pac_Bio_550_SEC_M_Di_HPLC_Columns_043f131056.jpg 156w," sizes="100vw" width="650" height="650"></p><ul><li>Ideal for AAV gene therapy characterization and quality control assessment due to selectivity of the dedicated smaller particle (3 μm) combined with wide-pore (550Å) size</li><li>Superior column-to-column and lot-to-lot reproducibility eliminates column variability as a concern in stability and QA/QC testing</li><li>High-efficiency peaks with excellent recovery</li><li>Higher resolution and throughput for fast turnaround time without sacrificing performance</li><li>Bioinert hardware to eliminate analyte adsorption</li></ul><h4><strong>Specifications</strong></h4><ul><li><strong>Max. Pressure: </strong>3500 psi (241 bar)</li><li><strong>Packing Material:</strong> Monodisperse Silica Resin</li><li><strong>Flow Rate: </strong>0.6 mL/min</li><li><strong>Temperature:</strong> 20°C to 60°C</li><li><strong>Phase:</strong> Size Exclusion</li><li><strong>Particle Size: </strong>3 μm</li><li><strong>pH: </strong>2 to 8</li></ul>

Thermo Scientific SureSTART Vials and Well Plates Collection

Start your analysis with confidence using SureSTART vials, caps, well plates, and kits—offering full compatibility, quality materials, and performance across three levels.

<h4><strong>Streamlined choice. Trusted quality.</strong></h4><p><strong>Start your analysis with confidence using Thermo Scientific™ SureSTART™ vials, caps, inserts, well plates, mats, and certified kits designed to meet your analytical, regulatory, and performance requirements. With full instrument compatibility, high material quality, and consistent performance across three defined levels, the SureSTART collection offers a smarter way to choose the right sample containment solution for your workflow.</strong></p><h3><strong>Why choose SureSTART?</strong></h3><ul><li><strong>Proven reliability</strong>: Every product is manufactured and certified to meet physical specifications—no weak links in your workflow.</li><li><strong>Clear selection</strong>: Three performance levels help you balance sensitivity, robustness, and cost, now visually marked with one, two, or three waves on the vial.</li><li><strong>Universal compatibility</strong>: Designed for seamless integration with all major GC, HPLC/UHPLC, and MS autosamplers across all vendors.</li><li><strong>Certified cleanliness</strong>: Products are manufactured using the purest glass and plastics with low extractables and leachables, including GOLD-grade and silanized glass.</li><li><strong>Maximum sample integrity</strong>: Minimize analyte loss and background peaks with precision-engineered sealing, surface chemistry, and material composition.</li><li><strong>Bulk savings &amp; simplified inventory</strong>: Available in multiple pack sizes, performance levels, and formats to support your lab’s needs and budget.</li></ul><h3><strong>The Three Performance Levels</strong></h3><ul><li><strong>Level 1 – Everyday analysis</strong>: For general-purpose GC/HPLC detection (e.g. UV/Vis, FID, RI). These chromatography-approved products are ideal for routine analyses with cost-efficiency in mind.</li><li><strong>Level 2 – High-throughput analysis</strong>: Designed for regulated labs requiring robust and reproducible data, especially when using MS detectors for routine quantification.</li><li><strong>Level 3 – High performance</strong>: For the most sensitive and selective analyses near the method detection limit. Packed in cleanroom environments and made with ultra-pure materials for maximum sample security and MS compatibility.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Sure_START_Vials_and_Well_Plates_Collection_5a8b0da936.jpg" alt="Thermo Scientific SureSTART Vials and Well Plates Collection: Three performance levels help you balance sensitivity, robustness, and cost, now visually marked with one, two, or three waves on the vial." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Sure_START_Vials_and_Well_Plates_Collection_5a8b0da936.jpg 245w," sizes="100vw" width="1182" height="270"></p><h3><strong>SureSTART Certified Vial and Cap Kits</strong></h3><ul><li><strong>Specification Certified</strong>: Routine analyses – Certified for physical specifications; no individual certificate.</li><li><strong>LC/GC Certified</strong>: Chromatography-grade – Tested for 15 physical parameters with LC-UV &amp; GC-FID; certificate included.</li><li><strong>MSCERT</strong>: For LC-MS/GC-MS – Certified low-adsorption kits tested with MS; includes SureStop™ vials with AVCS™ caps.</li><li><strong>MSCERT+</strong>: For trace-level MS or DIA – Pre-cleaned, tested with LC-MS/GC-MS, and sold only as kits to ensure purity.</li><li><strong>Application Certified</strong>: Pre-matched kits for specific instruments or validated applications.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Sure_START_Vials_and_Well_Plates_Collection_2_fef6049d71.jpg" alt="Thermo Scientific SureSTART Vials and Well Plates Collection: There are several factors to consider when choosing a vial or well plate for your application. The table below will help guide you through this process to determine what type of product/performance level is most suitable for your application requirements." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Sure_START_Vials_and_Well_Plates_Collection_2_fef6049d71.jpg 204w," sizes="100vw" width="1515" height="1159"></p><h3><strong>SureSTART Well Plates and Mats</strong></h3><p>Thermo Scientific™ WebSeal™ well plates are ideal for laboratories seeking to increase autosampler capacity, reduce solvent usage, and streamline high-throughput workflows. Available in <strong>96- and 384-well formats</strong>, they offer a certified alternative to traditional vials and are fully compatible with automated SPE/SLE platforms.</p><ul><li><strong>Space-saving efficiency</strong>: Replace vials with well plates to increase sample capacity up to 8× and reduce storage footprint.</li><li><strong>Flexible performance levels</strong>:<ul><li><strong>Level 1: Standard plates for routine</strong>, non-regulated use (GC-tested).</li><li><strong>Level 2: Low-bleed plates and high-performance mats</strong>, validated for LC-MS/GC-MS.</li><li><strong>Level 3: Premium WebSeal Plate+</strong> with glass-coated plastic wells—ideal for trace analytes and protein adsorption control.</li></ul></li><li><strong>Solvent stability and clean sample contact</strong>: WebSeal Plate+ uses nanolayered silicon dioxide for minimal extractables and ultra-low adsorption.</li><li><strong>Compatible sealing options</strong>:<ul><li><strong>Silicone mats: </strong>For long-term storage and consistent results.</li><li><strong>Pre-slit mats: </strong>For autosampler injection without evaporation or contamination.</li><li><strong>Adhesive seals: </strong>For single-use workflows and re-sealing options with cavity protection.</li></ul></li></ul><p>Whether you work with polar solvents, proteins, or trace-level analyses, SureSTART well plates and sealing accessories help you optimize throughput, precision, and data confidence across all chromatography workflows.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Sure_START_Vials_and_Well_Plates_Collection_3_abce3dd960.jpg" alt="Thermo Scientific SureSTART Vials and Well Plates Collection: Selecting the perfect Thermo Scientific WebSeal well plates and mats for your chromatography requirements is easy using our selector tools and resources." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Sure_START_Vials_and_Well_Plates_Collection_3_abce3dd960.jpg 245w," sizes="100vw" width="1516" height="902"></p>

Thermo Scientific LCQUAN Quantitative Software

LCQUAN is a robust, 21 CFR Part 11-compliant software for LC-MS/MS bioanalysis, providing complete tools for data acquisition, review, and secure management in drug development workflows.

<h4><strong>21 CFR Part 11-compliant software for quantitative LC-MS/MS data acquisition and management</strong></h4><p><strong>Thermo Scientific™ LCQUAN™ quantitative software is a robust, regulatory-compliant data system tailored for bioanalytical laboratories conducting LC-MS/MS assays. Developed in close collaboration with pharmaceutical industry experts, LCQUAN provides all the tools needed to acquire, process, review, and securely manage quantitative data across global drug development workflows.</strong></p><h3><strong>Key Features</strong></h3><h4><strong>Regulatory Compliance</strong></h4><ul><li>Fully compliant with FDA 21 CFR Part 11 requirements for electronic records and signatures</li><li>Enables secure submission of electronic documents to regulatory agencies, including the FDA</li></ul><h4><strong>Comprehensive Workflow</strong></h4><ul><li>Guides users step-by-step through acquisition, method development, data review, processing, reporting, and export</li><li>Supports import of sequence information from external systems</li><li>Streamlines interaction with Thermo Scientific™ Watson LIMS™ for GLP-compliant bioanalytical studies</li></ul><h4><strong>Secure Data Management</strong></h4><ul><li>Enables data processing on networked systems, including secure remote disks</li><li>Centralized, workbook-style data storage for easy archiving and retrieval</li><li>Multi-level user privileges—from full system access to read-only modes</li></ul><h4><strong>Seamless LIMS Integration</strong></h4><ul><li>Bi-directional communication with Watson LIMS facilitates study tracking, chromatogram review, auditing, and compliance</li><li>Optimized for regulated pharmaceutical workflows from discovery through clinical trials</li></ul><h4><strong>Proven Platform</strong></h4><ul><li>Part of an integrated Thermo Scientific LC-MS/MS solution suite, including TSQ Series mass spectrometers and FAIMS interface technology</li><li>Ensures high sensitivity, robustness, and reproducibility for regulated bioanalytical assays</li></ul>

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