Meeting EU Drinking Water Standards: The Critical Role of Sample Prep in Trace Contaminant Analysis

Although modern agriculture needs to be based on accurate real-time data on soil, plant, and environmental conditions, affordable, sufficiently sensitive, and robust monitoring devices for this purpose are currently missing. According to scientists, low-cost sensors based on new smart materials and printing technologies offer a suitable solution. The results of multidisciplinary research thus far and proposals for the development of these devices have been presented by researchers from Czechia, Great Britain, Spain, and the USA in a review article in the prestigious journal <a target="_blank" rel="noopener noreferrer" href="https://www.nature.com/articles/s41467-026-68778-6#Abs1">Nature Communications</a>.“Sensor technologies for monitoring plant health are still in their infancy. Only simple sensors capable of monitoring basic parameters such as pH, soil moisture, or temperature are commonly available on the market. However, if farmers are to face current challenges, including climate change, and ensure sufficient food for humanity, they need much more effective tools that will enable them to monitor, for example, various pathogens, including bacteria and fungi. In our opinion, a suitable solution is a combination of new smart materials and printing for the production of inexpensive, durable, and scalable materials,” said the article’s first author, David Panáček from CATRIN, who worked on the study during his internship at Imperial College London.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CATRIN_Soucasne_senzory_nestaci_Vedci_navrhuji_novou_cestu_ke_sledovani_zdravi_rostlin_b4014952a3.jpg" alt="CATRIN: David Panáček" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CATRIN_Soucasne_senzory_nestaci_Vedci_navrhuji_novou_cestu_ke_sledovani_zdravi_rostlin_b4014952a3.jpg 208w," sizes="100vw" width="1536" height="1152">Sensors for monitoring plant health, for example, lag behind similar devices used in human medicine. According to the authors, advances in materials science, which will enable the development of scalable sensor technologies, play a key role in this potential shift. “Printing techniques, including inkjet printing, screen printing, aerosol printing, 3D printing, and direct laser writing, offer flexible ways to produce flexible sensors, large-area sensors, and sensors integrated directly into plants. The review article summarizes recent advances in printable low-dimensional materials for agricultural sensors, analyzes their physico-chemical properties in relation to sensor performance, and discusses key challenges and future opportunities requiring interdisciplinary integration,” said one of the corresponding authors, Michal Otyepka.The research brought together materials scientists, chemists, biologists, sensing experts, and printing technology specialists. Materials research and the use of graphene-based smart materials were led by scientists from CATRIN at Palacký University and VŠB-Technical University of Ostrava. Plant biologists from CATRIN contributed their knowledge of plant development, their responses to stress conditions, and the monitoring of their properties. Researchers from Imperial College London took care of the electronics, while representatives from<a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/36"> CEITEC – VUT</a> focused on printing technologies. The team also included leading experts in sensing from the Catalan Institute of Nanoscience and Nanotechnology in Barcelona, and Joseph Wang of the University of California San Diego, the “father of sensing and electrochemistry,” also contributed his extensive knowledge.“This is a groundbreaking study on this topic, which has managed to attract some truly big names in their respective fields. Last but not least, the study demonstrates that interdisciplinarity at CATRIN gives rise to completely new and promising research topics, such as plant sensing and its use for studying plant-environment interactions and smart agriculture,” added another corresponding author, Nuria De Diego.

Current sensors are not good enough. Scientists propose a new way to monitor plant health

In this episode of the Concentrating on Chromatography podcast, host David Oliva interviews Ainslie Chen about her cutting-edge research on hemoglobin variant testing using liquid chromatography-high resolution mass spectrometry (LC-HR-MS). Ainslie discusses her novel method for separating and identifying hemoglobin subunits with mass shifts less than 1 Da, overcoming critical limitations in conventional clinical assays.Hear firsthand how her team developed an LC-HR-MS workflow using a C4 reversed-phase column, tackled technical challenges (including why C18 columns fell short), and achieved unprecedented sensitivity for variant detection in both adult and neonatal samples. The conversation touches on the potential of mass spectrometry to revolutionize clinical diagnostics, the importance of reproducibility, barriers to adoption in routine labs, and how teamwork drives scientific innovation.Perfect for analytical chemists, clinical laboratorians, and anyone interested in the future of protein variant analysis, this episode also features Ainslie’s advice for early-career scientists and insights from her first ACS poster presentation.<h4>Key Highlights:</h4><ul><li>Motivation behind improving hemoglobinopathy testing &nbsp;</li><li>Technical advantages of LC-HR-MS over gene sequencing and CE &nbsp;</li><li>The crucial role of the C4 column in resolving challenging samples &nbsp;</li><li>Critical parameters for reproducible LC-HR-MS workflows &nbsp;</li><li>Barriers and outlook for clinical adoption of advanced mass spectrometry &nbsp;</li><li>The value of teamwork and mentorship in scientific research &nbsp;</li><li>Direct insights from recent ACS conference experiences</li></ul><h3>Video transcription</h3>In this interview, Ainslie Chen discusses her research on improving the detection and identification of hemoglobin variants using liquid chromatography coupled with high-resolution mass spectrometry (LC-HRMS). The work addresses limitations of conventional hemoglobinopathy testing, which often struggles to resolve very small mass differences between closely related hemoglobin subunits. Because even a single amino-acid substitution can significantly alter hemoglobin structure and function, high analytical resolution is essential for accurate diagnosis of conditions such as anemia and sickle cell disease.Chen explains why her team selected LC-HRMS over established clinical techniques like capillary electrophoresis and gene sequencing. While sequencing offers excellent accuracy, it is time-consuming, costly, and requires extensive sample preparation, making it impractical for routine clinical workflows. Capillary electrophoresis enables subunit separation but lacks the resolving power needed to distinguish variants differing by less than one Dalton. In contrast, high-resolution mass spectrometry provides both structural specificity and sensitivity, enabling confident identification of subtle hemoglobin variants with minimal sample preparation.A key methodological insight from the project was the use of a C4 reversed-phase LC column instead of the more common C18 column. Chen describes how the shorter carbon chain and larger pore size of C4 columns improved protein elution and reduced denaturation, leading to more reproducible separations. Critical parameters for reproducibility included consistent mobile-phase composition (0.1% formic acid in water and acetonitrile), controlled temperature (60 °C for LC, ~320 °C capillary temperature), and stable chromatographic conditions.Beyond hemoglobin analysis, Chen highlights the broader potential of high-resolution mass spectrometry in proteoform analysis and clinical diagnostics, including emerging applications in cancer detection. She acknowledges current barriers to clinical adoption—such as energy demands and instrument infrastructure—but points to advances like miniaturized mass spectrometers as promising steps toward wider use. The interview concludes with advice for young scientists: don’t hesitate to reach out to mentors, embrace collaboration, and view analytical chemistry as a versatile tool that bridges medicine, biology, environmental science, and beyond.<blockquote>This text has been automatically transcribed from a video presentation using AI technology. It may contain inaccuracies and is not guaranteed to be 100% correct.</blockquote><blockquote><h4>Concentrating on Chromatography Podcast</h4>Dive into the frontiers of chromatography, mass spectrometry, and sample preparation with host David Oliva. Each episode features candid conversations with leading researchers, industry innovators, and passionate scientists who are shaping the future of analytical chemistry. From decoding PFAS detection challenges to exploring the latest in AI-assisted liquid chromatography, this show uncovers practical workflows, sustainability breakthroughs, and the real-world impact of separation science. Whether you’re a chromatographer, lab professional, or researcher you'll discover inspiring content!You can find Concentrating on Chromatography Podcast in podcast apps:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://open.spotify.com/show/1wZg67rCjoGju4yhqxI3tL">Spotify</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podcasts.apple.com/tz/podcast/concentrating-on-chromatography/id1788429185">Apple podcast</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podscan.fm/podcasts/concentrating-on-chromatography">podscan</a></li></ul>and on <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/@ChromatographyTalk/videos">YouTube channel</a></blockquote>

Unlocking Hemoglobin Variant Detection: LC-HR-MS Breakthrough with Ainslie Chen

Article

Video

Environment

Scientific article

Interview

Science and research

The Czech Advanced Technology and Research Institute (CATRIN) at Palacký University is a cutting-edge scientific hub dedicated to advancing research in the fields of nanotechnology, biotechnology, and biomedicine. At its core, CATRIN boasts outstanding scientific teams, featuring international researchers. We emphasize interdisciplinarity, foster global collaborations, and work to translate our research findings into practical applications.

CATRIN

Organomation, founded in 1959, designs and manufactures high-quality nitrogen evaporators and extraction systems. Known for innovation and durability, their lab instruments are used globally for efficient sample preparation with strong customer support.

Organomation

Thermo Scientific Dionex IonPac CS19-4μm IC Columns

High-capacity ion-exchange column with 4 μm resin for highest resolution of cations and polar amines in complex samples. Enables fast, reliable separations and cost-effective operation with HPIC systems.

Attain the optimal combination of chromatographic speed and high resolution using the new Thermo Scientific™ Dionex™ IonPac™ CS19-4μm Capillary, Analytical, &amp; Guard Column. This high-capacity, high-resolution carboxylate-functionalized column provides excellent resolution of common cations, small polar amines, and polyvalent amines in complex sample matrices such as power plant waters treated with ammonium, morpholine, or ethanolamine, chemical additives, chemical process solutions, scrubber solutions, personal care products, and food samples. Compared to the Thermo Scientific™ Dionex™ IonPac™ CS19 column, this column uses smaller resin particles for more efficient separations resulting in more accurate peak integration and more reliable results.<h5>Highest Resolution Separation of Common Cations and Small Polar Amines in Diverse Matrices</h5><ul><li>Highest resolution, through the use of smaller resin particles, of common cations and small polar amines in complex sample matrices</li><li>Higher peak efficiency and increased peak resolution for more consistent integration and more reliable results</li><li>Easily transfer applications from the Dionex IonPac CS19 column to the 4 μm column due to the similar selectivity</li><li>Simple gradient separation of small polar amines (including alkanolamines and methylamines), and moderately hydrophobic and polyvalent amines (including biogenic amines and alkyl diamines)</li><li>High capacity facilitates injection of more concentrated samples without column overloading or peak broadening</li><li>Compatible with moderate amounts of organic solvents, excluding alcohols, to enhance analyte solubility, modify column selectivity, and facilitate effective column clean-up</li></ul><h5>Use With a High-Pressure IC System</h5>Higher resolution is achieved through the use of smaller resin particles, which produce a column backpressure over 3000 psi at the standard flow rates. A high-pressure IC system, such as the Thermo Scientific™ Dionex™ ICS-5000+ HPIC™ or the Dionex ICS-4000 Capillary HPIC system is required to operate this column under standard conditions and take advantage of elevated flow rates and faster run times.<h5>Reduce Operating Costs With Lower Eluent Requirements</h5>The Dionex IonPac CS19-4μm capillary column provides the same performance as the standard bore and microbore Dionex IonPac CS19-4μm columns because it is packed with the same material. Operating costs are reduced because the capillary system operates at only 1% of the eluent flow rate of the standard bore system, requiring less eluent and producing less waste.<h5>Multiple Formats Available for Application Flexibility</h5><ul><li>4x250mm, 2x250mm analytical columns</li><li>4x50mm, 2x50mm guard columns</li><li>0.4x250mm capillary column, 0.4x50mm capillary guard column</li><li>Longer 250mm columns facilitate higher resolution separations of more complex sample matrices</li><li>Smaller i.d. columns provide higher mass sensitivity, eluent and reagent conservation and lower operating costs</li></ul><h4>Specifications</h4><ul><li>Crosslinking: 55% DVB</li><li>Column Capacity: 2410 μeq</li><li>For Use With (Application): Cation Exchange</li><li>Max. Pressure: 5000 psi (345 bar)</li><li>Solvent Compatibility: Acidic Eluents (pH 0 to 7), 10% HPLC Solvents, Alcohols Should be Avoided</li><li>Stationary phase: IonPac CS19-4μm</li><li>Format: Standard Bore</li></ul>

Thermo Scientific Dionex IonPac CS20 IC Columns

Analyze inorganic cations and amines using the Thermo Scientific™ Dionex™ IonPac™ CS20 ion chromatography (IC) columns.

Analyze inorganic cations and amines using the Thermo Scientific™ Dionex™ IonPac™ CS20 ion chromatography (IC) columns. Designed to complement Dionex IonPac CS18 and Dionex IonPac CS19 columns, the Dionex IonPac CS20 columns provide a large separation window between monovalent and divalent cations. This allows most amines to elute after the alkali metals but before the alkaline earth metals, moving the amines away from matrix ions that would normally make quantitation difficult. Its selectivity makes the Dionex IonPac CS20 particularly useful for determining a variety of alkyl and alkanol amines.<h5>Superior performance in the separation of common inorganic cations and amines</h5><ul><li>Use the high capacity Dionex IonPac CS20 to determine inorganic cations and amines including methylamines, ethylamines, ethanolamines, and alkanolamines in diverse sample matrices</li><li>Unique stationary phase functionalized with a combination of sulfonic, phosphonic, and carboxylic acid groups can tolerate acidic samples containing up to 100mM hydronium ion (pH 1) with minimum loss of performance</li><li>Operable over a wide temperature range (15-70°C) to facilitate method development and improve critical pair separations</li><li>Compatible with 100% organic solvents (acetonitrile and acetone) to enhance analyte solubility, modify column selectivity, and facilitate effective column clean-up</li></ul><h5>Use with a high-pressure IC system</h5>A high-pressure IC system, such as the Thermo Scientific™ Dionex™ ICS-5000+ HPIC™, Dionex Integrion™ HPIC system, or the Dionex ICS-4000 Capillary HPIC system is required to operate this column under standard conditions.<h5>Reduce operating costs with lower eluent requirements</h5>The Dionex IonPac CS20 capillary columns provide the same performance as the standard bore and microbore Dionex IonPac CS20 columns because they are packed with the same material. Operating costs are reduced because the capillary system operates at only 1% of the eluent flow rate of the standard bore system, requiring less eluent and producing less waste.<h5>Multiple Formats Available</h5><ul><li>4x250mm and 2x250mm analytical columns</li><li>4x50mm and 2x50mm analytical guard columns</li><li>0.4x250mm capillary columns</li><li>0.4x50mm capillary guard columns</li><li>Smaller i.d. columns provide higher mass sensitivity, conserve eluent and reagents, and reduce operating costs</li></ul><h4>Specifications</h4><ul><li>Crosslinking: 55% DVB</li><li>Column Capacity: 3000 μeq</li><li>For Use With (Application): Cation Exchange</li><li>Max. Pressure: 5000 psi (345 bar)</li><li>Solvent Compatibility: pH 0 to 7, 0 to 100% Organic HPLC Solvents, Alcohols Should be Avoided</li><li>Stationary phase: Macroporous Resin</li><li>Format: Standard Bore</li><li>Packing Material: Ethylvinylbenzene/Divinylbenzene</li></ul>

Thermo Scientific Dionex IonPac CS21-Fast-4μm IC Columns

Resolve quaternary amine cationic polar pesticides including chlormequat, mepiquat, paraquat, and diquat with the Thermo Scientific™ Dionex™ IonPac™ CS21-Fast-4μm column. 

Resolve quaternary amine cationic polar pesticides including chlormequat, mepiquat, paraquat, and diquat with the Thermo Scientific™ Dionex™ IonPac™ CS21-Fast-4μm column. The unique selectivity of the Dionex IonPac CS21-Fast-4μm column allows it to resolve trace amounts of cationic polar pesticides in high ionic strength matrices within approximately fifteen minutes using an electrolytically generated MSA gradient. Quaternary amines are eluted away from matrix cations, making the Dionex IonPac CS21-Fast-4μm column ideal for IC-MS/MS applications where matrix ions are diverted to waste.<h5>Superior Chromatographic Performance</h5><ul><li>High capacity allows injection of complex matrices without overloading the column while maintaining excellent peak shapes for lower concentration analytes.</li><li>Quickly separate trace levels of the four major quaternary amine cationic polar pesticides chlormequat, mepiquat, paraquat, and diquat in high ionic strength matrices using an MSA gradient.</li><li>Separate other cationic pesticides of interest including diethanolamine, triethanolamine, N-N-dimethylhydrazine, trimethylsulfonium, morpholine, melamine, streptomycin, and nereistoxin.</li></ul><h5>Specifically designed for IC-MS/MS applications</h5><ul><li>Completely resolves paraquat and diquat, species with similar masses.</li><li>Available in microbore format that is compatible with MS flow rates.</li><li>Selectivity allows matrix ions to be diverted to waste which keeps the MS source cleaner.</li><li>Solvent compatible (up to 100% acetonitrile and 20% isopropyl alcohol).</li><li>Fast analysis of cationic polar pesticides in food, beverages, and environmental waters.</li></ul><h5>Use with a High-Pressure IC system</h5>A high-pressure IC system, such as the <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/410">Thermo Scientific™ Dionex™ ICS-6000 HPIC system</a> or <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/408">Thermo Scientific™ Dionex™ Integrion™ HPIC system</a> is required to operate this column under standard conditions.<h4>Specifications</h4><ul><li>Crosslinking: 80% DVB</li><li>Column Capacity: 110 μeq</li><li>For Use With (Application): Cation Exchange</li><li>Max. Pressure: 5000 psi (345 bar)</li><li>Solvent Compatibility: pH 0-7, HPLC solvents (100% acetonitrile and up to 20% isopropyl alcohol), primary and secondary alcohols should be avoided)</li><li>Format: Microbore</li><li>Packing Material: Ethylvinylbenzene/Divinylbenzene</li></ul>

Thermo Scientific SurePac Bio 550 SEC MDi HPLC Columns

SurePac™ Bio 550 SEC MDi™ column delivers high-resolution, reproducible AAV size-based separations with 3 μm silica, 550 Å pores, and bioinert hardware for optimal recovery and QC reliability.

Experience the future of Size-Exclusion Chromatography (SEC) with SurePac™ Bio 550 SEC MDi™ analytical columns and guards exclusively designed to deliver robust and reproducible performance at high resolution and throughput to accelerate your therapeutics analysis process. The column's groundbreaking MDi™ technology integrates our advanced 3 μm monodisperse silica particle platform with bioinert hardware to ensure superior reliability for best sample recovery. SurePac™ Bio 550 SEC MDi™ column is ideal for AAV gene therapeutics analysis and offers excellent selectivity due to the dedicated smaller particle (3 μm) size combined with wide-pore (550Å) for separating monomeric AAVs from aggregates based on their size differences.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Sure_Pac_Bio_550_SEC_M_Di_HPLC_Columns_3_8391a584e0.jpg" alt="Thermo Scientific: SEM image of 3μm monodisperse silica particles (left) vs. 3 μm polydisperse particles (right)" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Sure_Pac_Bio_550_SEC_M_Di_HPLC_Columns_3_8391a584e0.jpg 245w," sizes="100vw" width="1023" height="508">SurePac Bio 550 SEC MDi columns and guards are based on high-purity, spherical, porous (550 Å), 3 μm monodispersed silica particles that are covalently modified with a proprietary diol hydrophilic layer. This unique design yields shorter diffusion distances and enhanced reproducible mass transfer and narrower peaks. The consistent size of these particles facilitates precise control over media synthesis and column packing, significantly improving column-to-column and lot-to-lot reproducibility. The columns are housed in a hydrophilic bioinert-coated stainless-steel hardware to eliminate secondary interactions, ensuring optimal performance during the initial injection process.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Sure_Pac_Bio_550_SEC_M_Di_HPLC_Columns_043f131056.jpg" alt="Thermo Scientific: SurePac Bio 550 SEC MDi HPLC Columns" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Sure_Pac_Bio_550_SEC_M_Di_HPLC_Columns_043f131056.jpg 156w," sizes="100vw" width="650" height="650"><ul><li>Ideal for AAV gene therapy characterization and quality control assessment due to selectivity of the dedicated smaller particle (3 μm) combined with wide-pore (550Å) size</li><li>Superior column-to-column and lot-to-lot reproducibility eliminates column variability as a concern in stability and QA/QC testing</li><li>High-efficiency peaks with excellent recovery</li><li>Higher resolution and throughput for fast turnaround time without sacrificing performance</li><li>Bioinert hardware to eliminate analyte adsorption</li></ul><h4>Specifications</h4><ul><li>Max. Pressure: 3500 psi (241 bar)</li><li>Packing Material: Monodisperse Silica Resin</li><li>Flow Rate: 0.6 mL/min</li><li>Temperature: 20°C to 60°C</li><li>Phase: Size Exclusion</li><li>Particle Size: 3 μm</li><li>pH: 2 to 8</li></ul>

Thermo Scientific SureSTART Vials and Well Plates Collection

Start your analysis with confidence using SureSTART vials, caps, well plates, and kits—offering full compatibility, quality materials, and performance across three levels.

<h4>Streamlined choice. Trusted quality.</h4>Start your analysis with confidence using Thermo Scientific™ SureSTART™ vials, caps, inserts, well plates, mats, and certified kits designed to meet your analytical, regulatory, and performance requirements. With full instrument compatibility, high material quality, and consistent performance across three defined levels, the SureSTART collection offers a smarter way to choose the right sample containment solution for your workflow.<h3>Why choose SureSTART?</h3><ul><li>Proven reliability: Every product is manufactured and certified to meet physical specifications—no weak links in your workflow.</li><li>Clear selection: Three performance levels help you balance sensitivity, robustness, and cost, now visually marked with one, two, or three waves on the vial.</li><li>Universal compatibility: Designed for seamless integration with all major GC, HPLC/UHPLC, and MS autosamplers across all vendors.</li><li>Certified cleanliness: Products are manufactured using the purest glass and plastics with low extractables and leachables, including GOLD-grade and silanized glass.</li><li>Maximum sample integrity: Minimize analyte loss and background peaks with precision-engineered sealing, surface chemistry, and material composition.</li><li>Bulk savings &amp; simplified inventory: Available in multiple pack sizes, performance levels, and formats to support your lab’s needs and budget.</li></ul><h3>The Three Performance Levels</h3><ul><li>Level 1 – Everyday analysis: For general-purpose GC/HPLC detection (e.g. UV/Vis, FID, RI). These chromatography-approved products are ideal for routine analyses with cost-efficiency in mind.</li><li>Level 2 – High-throughput analysis: Designed for regulated labs requiring robust and reproducible data, especially when using MS detectors for routine quantification.</li><li>Level 3 – High performance: For the most sensitive and selective analyses near the method detection limit. Packed in cleanroom environments and made with ultra-pure materials for maximum sample security and MS compatibility.</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Sure_START_Vials_and_Well_Plates_Collection_5a8b0da936.jpg" alt="Thermo Scientific SureSTART Vials and Well Plates Collection: Three performance levels help you balance sensitivity, robustness, and cost, now visually marked with one, two, or three waves on the vial." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Sure_START_Vials_and_Well_Plates_Collection_5a8b0da936.jpg 245w," sizes="100vw" width="1182" height="270"><h3>SureSTART Certified Vial and Cap Kits</h3><ul><li>Specification Certified: Routine analyses – Certified for physical specifications; no individual certificate.</li><li>LC/GC Certified: Chromatography-grade – Tested for 15 physical parameters with LC-UV &amp; GC-FID; certificate included.</li><li>MSCERT: For LC-MS/GC-MS – Certified low-adsorption kits tested with MS; includes SureStop™ vials with AVCS™ caps.</li><li>MSCERT+: For trace-level MS or DIA – Pre-cleaned, tested with LC-MS/GC-MS, and sold only as kits to ensure purity.</li><li>Application Certified: Pre-matched kits for specific instruments or validated applications.</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Sure_START_Vials_and_Well_Plates_Collection_2_fef6049d71.jpg" alt="Thermo Scientific SureSTART Vials and Well Plates Collection: There are several factors to consider when choosing a vial or well plate for your application. The table below will help guide you through this process to determine what type of product/performance level is most suitable for your application requirements." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Sure_START_Vials_and_Well_Plates_Collection_2_fef6049d71.jpg 204w," sizes="100vw" width="1515" height="1159"><h3>SureSTART Well Plates and Mats</h3>Thermo Scientific™ WebSeal™ well plates are ideal for laboratories seeking to increase autosampler capacity, reduce solvent usage, and streamline high-throughput workflows. Available in 96- and 384-well formats, they offer a certified alternative to traditional vials and are fully compatible with automated SPE/SLE platforms.<ul><li>Space-saving efficiency: Replace vials with well plates to increase sample capacity up to 8× and reduce storage footprint.</li><li>Flexible performance levels:<ul><li>Level 1: Standard plates for routine, non-regulated use (GC-tested).</li><li>Level 2: Low-bleed plates and high-performance mats, validated for LC-MS/GC-MS.</li><li>Level 3: Premium WebSeal Plate+ with glass-coated plastic wells—ideal for trace analytes and protein adsorption control.</li></ul></li><li>Solvent stability and clean sample contact: WebSeal Plate+ uses nanolayered silicon dioxide for minimal extractables and ultra-low adsorption.</li><li>Compatible sealing options:<ul><li>Silicone mats: For long-term storage and consistent results.</li><li>Pre-slit mats: For autosampler injection without evaporation or contamination.</li><li>Adhesive seals: For single-use workflows and re-sealing options with cavity protection.</li></ul></li></ul>Whether you work with polar solvents, proteins, or trace-level analyses, SureSTART well plates and sealing accessories help you optimize throughput, precision, and data confidence across all chromatography workflows.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Sure_START_Vials_and_Well_Plates_Collection_3_abce3dd960.jpg" alt="Thermo Scientific SureSTART Vials and Well Plates Collection: Selecting the perfect Thermo Scientific WebSeal well plates and mats for your chromatography requirements is easy using our selector tools and resources." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Sure_START_Vials_and_Well_Plates_Collection_3_abce3dd960.jpg 245w," sizes="100vw" width="1516" height="902">

Thermo Scientific LCQUAN Quantitative Software

LCQUAN is a robust, 21 CFR Part 11-compliant software for LC-MS/MS bioanalysis, providing complete tools for data acquisition, review, and secure management in drug development workflows.

<h4>21 CFR Part 11-compliant software for quantitative LC-MS/MS data acquisition and management</h4>Thermo Scientific™ LCQUAN™ quantitative software is a robust, regulatory-compliant data system tailored for bioanalytical laboratories conducting LC-MS/MS assays. Developed in close collaboration with pharmaceutical industry experts, LCQUAN provides all the tools needed to acquire, process, review, and securely manage quantitative data across global drug development workflows.<h3>Key Features</h3><h4>Regulatory Compliance</h4><ul><li>Fully compliant with FDA 21 CFR Part 11 requirements for electronic records and signatures</li><li>Enables secure submission of electronic documents to regulatory agencies, including the FDA</li></ul><h4>Comprehensive Workflow</h4><ul><li>Guides users step-by-step through acquisition, method development, data review, processing, reporting, and export</li><li>Supports import of sequence information from external systems</li><li>Streamlines interaction with Thermo Scientific™ Watson LIMS™ for GLP-compliant bioanalytical studies</li></ul><h4>Secure Data Management</h4><ul><li>Enables data processing on networked systems, including secure remote disks</li><li>Centralized, workbook-style data storage for easy archiving and retrieval</li><li>Multi-level user privileges—from full system access to read-only modes</li></ul><h4>Seamless LIMS Integration</h4><ul><li>Bi-directional communication with Watson LIMS facilitates study tracking, chromatogram review, auditing, and compliance</li><li>Optimized for regulated pharmaceutical workflows from discovery through clinical trials</li></ul><h4>Proven Platform</h4><ul><li>Part of an integrated Thermo Scientific LC-MS/MS solution suite, including TSQ Series mass spectrometers and FAIMS interface technology</li><li>Ensures high sensitivity, robustness, and reproducibility for regulated bioanalytical assays</li></ul>

Thermo Scientific Cindion Combustion Ion Chromatography System

Fully integrated C-IC system for automated screening of halogens, sulfur compounds, and PFAS in solid, liquid, and gas samples.

<h4>Automated halogen, sulfur, and PFAS screening in solid, liquid, and gas samples.</h4>The Thermo Scientific™ Cindion™ Combustion Ion Chromatography (C-IC) System is a fully integrated platform designed for screening corrosive and toxic halogens, sulfur compounds, and PFAS in a wide range of sample matrices. Whether analyzing solids, liquids, or gases, the system delivers low background levels, high sensitivity, and robust automated workflows—all in a compact footprint.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Cindion_Combustion_Ion_Chromatography_System_6_e1eda9de2f.jpg" alt="Thermo Scientific™ Cindion™ Combustion Ion Chromatography System" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Cindion_Combustion_Ion_Chromatography_System_6_e1eda9de2f.jpg 207w," sizes="100vw" width="650" height="490"><h3>Key Features</h3><ul><li>Compact system footprint: A novel combustion tube design ensures complete combustion over a shorter path, saving bench space and enhancing efficiency.</li><li>Fully automated workflow: From sample introduction to combustion, absorption, ion chromatographic separation, and data reporting—automation minimizes user intervention.</li><li>PFAS-free sample path: Components in the sample flow path are PFAS-free to eliminate contamination and enable ultra-sensitive PFAS detection (EPA Method 1621).</li><li>Reagent-Free Ion Chromatography (RFIC™): Automated eluent generation—just add water. Electrolytic suppression ensures consistent results with no external pump.</li><li>Versatile sample compatibility: Supports AOX and AOF determinations, as well as total and inorganic fluorine (TF/TIF) analysis in environmental, food, industrial, and petrochemical applications.</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/76">Chromeleon CDS integration</a>: A single software platform for full control of C-IC operations including sequence setup, system control, and reporting.</li><li>High throughput: Accommodates up to 45 solid or 120 liquid samples; includes smart hydration and reduced carryover for faster cycle times.</li><li>Application-ready: Backed by extensive application notes and 50+ years of Thermo Scientific expertise in ion chromatography.</li></ul><h3>Typical Applications</h3><ul><li>Environmental testing: AOX/AOF screening in water and wastewater; PFAS monitoring.</li><li>Food and packaging: Determination of organic fluorine content in food contact materials.</li><li>Petrochemicals: Halogen and sulfur analysis in fuels and oils to prevent equipment corrosion and meet emission standards.</li><li>Electronics and polymers: Detection of restricted brominated and fluorinated substances in plastics and E&amp;E components.</li><li>Mining and metallurgy: Screening for corrosive species in ores and geological samples.</li></ul><h3>System Components</h3><ul><li>Sample delivery module: Liquid/solid autosampler or gas injector.</li><li>Combustion/absorption unit: Integrated with autosampler and absorption tube.</li><li>Ion chromatography system: <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1078">Thermo Scientific™ Dionex™ IC with RFIC™</a> technology.</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Cindion_Combustion_Ion_Chromatography_System_3_79a361351d.jpg" alt="Thermo Scientific™ Cindion™ Combustion Ion Chromatography System" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Cindion_Combustion_Ion_Chromatography_System_3_79a361351d.jpg 243w," sizes="100vw" width="1509" height="971"><ol><li>Versatile autosampler. Load up to 45 (solid) or 120 (liquid) samples and easily switch between sample types without the need for tools.</li><li>Peltier cooled sample introduction. Reduce cycle time by accelerating the cooling of the boat between samples.</li><li>Compact combustion tube. Enhanced oxygen flow reduces time needed for complete combustion by increasing efficiency.</li><li>Smart hydration. Peristaltic pump delivers water only during sample combustion to minimize usage and preserve tube integrity.</li><li>Variable absorption volume. Optimize the absorption volume based on analytical need.</li><li>Reduced sample pathway. Lower baseline contamination and low sample carryover to decrease wash time between samples.</li><li>Advanced high-performance pump technology and electronics. Take advantage of a wider range of columns and chemistries improving speed and quality of results.</li><li>Function driven design. Quickly and safely access everything on the instrument.</li><li>Fast, flexible, convenient electrolytic suppression. Just connect the suppressor; no external pump or offline conditioning needed for regeneration.</li><li>Thermo Scientific™ Dionex™ Reagent-Free™ Ion Chromatography (RFIC™). Makes eluent preparation as simple as “just add water,” while ensuring more consistent results and enabling optimized gradient separations.</li></ol><h3>Results you can count on</h3>Getting analytes into solution is only part of the process. Being able to resolve them so that each peak can be accurately quantified is equally integral to reliable, accurate results.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Cindion_Combustion_Ion_Chromatography_System_4_96814c59fb.jpg" alt="Thermo Scientific™ Cindion™ Combustion Ion Chromatography System: Figure 1. PFAS as adsorbable organic fluorine (AOF) in municipal wastewater. C-IC can be used as a screening tool for presence of PFAS compounds by adsorption onto granular activated carbon, subsequent combustion and IC analysis." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Cindion_Combustion_Ion_Chromatography_System_4_96814c59fb.jpg 245w," sizes="100vw" width="1032" height="541">Our IC systems are paired with an unmatched portfolio of columns that are optimized to deliver the capacity, selectivity and resolution you need to get the answers you seek.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Cindion_Combustion_Ion_Chromatography_System_5_b47f92752f.jpg" alt="Thermo Scientific™ Cindion™ Combustion Ion Chromatography System: Figure 2. PFAS in food contact material. PFAS, as organic fluorine, can be determined by subtracting values for total inorganic fluorine (TIF) from total fluorine (TF) by IC and C-IC, respectively." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Cindion_Combustion_Ion_Chromatography_System_5_b47f92752f.jpg 245w," sizes="100vw" width="1184" height="588">

Thermo Scientific Vanquish Charged Aerosol Detectors

Thermo Scientific Vanquish CAD detectors deliver near-universal detection with high sensitivity, wide dynamic range, gradient compatibility, and compliance-ready design.

Expand your detection range and achieve accurate quantitation in High-Performance Liquid Chromatography (HPLC) with the near-universal Charged Aerosol Detector (CAD). Featuring a wide linear and dynamic range along with a uniform response independent of chemical structure, Thermo Scientific™ Vanquish™ CAD systems allow you to measure virtually all non-volatile and many semi-volatile analytes at low-nanogram to sub-nanogram concentrations. Confidently quantify both trace impurities and highly concentrated active compounds in a single analysis.<h3>Key Benefits</h3><ul><li>Standard-free quantitation of unknowns – uniform response enables reliable single-calibrant quantitation</li><li>Superior sensitivity – 10× lower LODs compared to ELSD, LOQs as low as 1–20 ng on-column</li><li>Wide dynamic range – linear up to 2 orders of magnitude, dynamic up to 4 orders</li><li>Compatible with gradient elution – maintain uniform response using inverse gradient, unlike RID</li><li>Integrated diverter valve – prevents contamination, directs unwanted matrix to waste, and improves quantitation of early-eluting compounds</li><li>Compliance and data integrity – full qualification of method parameters, audited flow path control, and seamless integration with <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/76">Thermo Scientific Chromeleon™ CDS</a></li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Vanquish_Charged_Aerosol_Detectors_1_e135b2d6fe.jpg" alt="Thermo Scientific Vanquish Charged Aerosol Detectors" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Vanquish_Charged_Aerosol_Detectors_1_e135b2d6fe.jpg 209w," sizes="100vw" width="650" height="486"><h3>Technical Features</h3><ul><li>Detection mode: Records up to 4 unique power values for optimal linear response</li><li>Gas requirements: Nitrogen (recommended) or compressed air</li><li>Dynamic range: Up to 4 orders of magnitude</li><li>Data collection rate: Up to 200 Hz</li><li>Compatibility: Designed for <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=37&amp;manufacturerItems=3&amp;search=Vanquish">Thermo Scientific™ Vanquish™ HPLC and UHPLC systems</a>; integration with other systems possible</li><li>Outputs: Digital and analog output options available</li><li>Safety features: Overpressure relief, leak sensing, high-temperature shutoff, flood prevention, and diagnostic monitoring</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Vanquish_Charged_Aerosol_Detectors_3_335506f860.jpg" alt="Thermo Scientific Vanquish Charged Aerosol Detectors" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Vanquish_Charged_Aerosol_Detectors_3_335506f860.jpg 245w," sizes="100vw" width="650" height="378"><h3>Product Portfolio</h3><ul><li>Vanquish CAD HP – broad temperature range (ambient, 10–100 °C), versatile high-performance configuration</li><li>Vanquish CAD FP – fixed-point operation at defined set temperatures (ambient, 35 °C, 50 °C, 70 °C)</li><li>Vanquish CAD H – heating-enabled design (ambient +5 to +100 °C)</li><li>Vanquish CAD F – fixed-temperature options (35 °C, 50 °C, 70 °C)</li><li>Vanquish CAD HP, Analog Output – full performance with analog signal output</li><li>Vanquish CAD HP, Digital Output – full performance with digital data output</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Vanquish_Charged_Aerosol_Detectors_2_795050403c.jpg" alt="Thermo Scientific Vanquish Charged Aerosol Detectors" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Vanquish_Charged_Aerosol_Detectors_2_795050403c.jpg 245w," sizes="100vw" width="650" height="397">

Thermo Scientific TSQ Certis Triple Quadrupole Mass Spectrometer

Triple quadrupole Thermo Scientific TSQ Certis built for long-term robustness, up to 900 SRMs/s, and stable performance across tens of thousands of injections using OptaMax Plus ion source and advanced Stellar ion optics.

The Thermo Scientific TSQ Certis is a high-performance triple quadrupole LC-MS/MS system designed for targeted quantitative analysis in demanding routine and regulated environments. Built on the proven <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/404">TSQ Altis Plus </a>platform, it integrates advanced front-end hardware, innovative ion optics, and compliance-ready software to deliver superior performance and uptime.Powered by the OptaMax Plus ion source and Stellar ion vector optics, TSQ Certis provides exceptional sensitivity, long-term robustness, and reproducible performance even for complex sample matrices. With an acquisition speed of up to 900 SRMs per second, the system is ideally suited for pharmaceutical, clinical, forensic toxicology, environmental, and food safety laboratories.Its rugged design supports tens of thousands of injections between cleanings, while an integrated early-warning maintenance system helps prevent unplanned downtime. Full compatibility with <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/76">Chromeleon CDS</a>, <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/77">TraceFinder</a>, <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1758">Xcalibur</a>, FreeStyle, and <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1764">mzCloud </a>ensures seamless integration into both routine and advanced analytical workflows.<h4>Key features</h4><ul><li>Triple quadrupole LC-MS/MS for targeted quantitation</li><li>Up to 900 SRMs/s for high-throughput workflows</li><li>OptaMax Plus ion source with enhanced vaporizer temperatures</li><li>Excellent sensitivity and signal stability</li><li>Fast polarity switching &lt; 5 ms</li><li>Rugged design with extended maintenance intervals</li><li>Compliance-ready software ecosystem</li><li>3-year standard factory warranty</li></ul><h4>Selected specifications</h4><ul><li>Type: Triple Quadrupole LC-MS</li><li>Mass range: 2–2010 m/z</li><li>Resolution: 0.2 FWHM</li><li>Acquisition speed: 900 SRMs/s</li><li>Weight: 112 kg</li><li>Dimensions (W × D × H): 833 × 660 × 703 mm</li><li>LC compatibility: <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=37&amp;search=vanquish">Vanquish LC</a>, Transcend LC</li><li>Ion sources: OptaMax Plus, OptiSpray, EASY-Spray NG, FAIMS Pro Duo, VeriSpray</li></ul><div><div><div><div><div><h3>Clinical research application: long-term instrument stability even with contaminant-heavy matrices</h3></div></div><div><div>Analyzing human whole blood by LC-MS presents persistent challenges: matrix contaminants can accumulate within the ion source and API stack, compromising signal integrity and reproducibility. Restoring data quality demands time-consuming maintenance. The TSQ Certis Mass Spectrometer proves its durability by maintaining stable, precise performance through tens of thousands of injections—minimizing downtime and maximizing throughput.</div></div></div></div></div><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_TSQ_Certis_Triple_Quadrupole_Mass_Spectrometer_0ec820459f.jpg" alt="Thermo Scientific TSQ Certis Triple Quadrupole Mass Spectrometer: Raw peak area of 15pg Ascomycin on column was determined in whole blood for 10,209 injections. The experiment was run over a 5-week period, and the system delivered an RSD of 13.8% with no cleaning of the ion transfer tube or the sweep cone." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_TSQ_Certis_Triple_Quadrupole_Mass_Spectrometer_0ec820459f.jpg 245w," sizes="100vw" width="2048" height="1152"><div><div><div><div><div><h3>Endocrinology application: superior performance for steroid quantitation</h3></div></div><div><div>Liquid chromatography coupled with triple quadrupole (LC–QqQ) mass spectrometry has become the industry standard for the quantitative determination of steroids in biological matrices. Compared to immunoassays, LC–QqQ MS offers superior analytical specificity, lower detection limits, and improved reproducibility, making it ideal for regulated pharmacokinetic, endocrinological, and clinical research applications. The TSQ Certis Mass Spectrometer provides the speed, specificity, and ultra-high sensitivity necessary for reliable steroid quantitation.&nbsp;</div></div></div></div></div><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_TSQ_Certis_Triple_Quadrupole_Mass_Spectrometer_2_3a48cc4deb.jpg" alt="Thermo Scientific TSQ Certis Triple Quadrupole Mass Spectrometer: LC SRM chromatogram of 18 steroids in BSA run using the Thermo Scientific Vanquish Flex UHPLC System and TSQ Certis Mass Spectrometer. This is an 8-minute chromatography run utilizing the Thermo Scientific Hypersil Gold C18 Column for separation. The samples were protein crashed from 0.05% BSA in PBS, and injecting 5µL." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_TSQ_Certis_Triple_Quadrupole_Mass_Spectrometer_2_3a48cc4deb.jpg 245w," sizes="100vw" width="2048" height="1152"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_TSQ_Certis_Triple_Quadrupole_Mass_Spectrometer_3_62ede15e59.jpg" alt="Thermo Scientific TSQ Certis Triple Quadrupole Mass Spectrometer: Highly sensitive triple quadrupole instrumentation, often with advanced ion optics, is needed for Dihydrotestosterone (DHT) quantitation. The DHT quantitation peak and calibration curve of DHT run at 0.4pg on column with an RSD of 8.2%." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_TSQ_Certis_Triple_Quadrupole_Mass_Spectrometer_3_62ede15e59.jpg 245w," sizes="100vw" width="2048" height="1152">

Thermo Scientific VeriSpray PaperSpray Ion Source for Mass Spectrometry

Thermo Scientific VeriSpray PaperSpray Ion Source enables direct MS analysis without chromatography, delivering rapid results, simplified workflows, high throughput, and reduced cost per test.

The Thermo Scientific VeriSpray PaperSpray Ion Source is a mass spectrometry ionization source designed to enable direct sample analysis without chromatographic separation. Based on paper spray ionization technology, it significantly simplifies analytical workflows while delivering rapid and reliable MS results from complex sample matrices.Samples are applied to a paper substrate, wetted with solvent, and ionized by applying a high voltage. The resulting ions are introduced directly into the mass spectrometer via electrospray ionization, eliminating the need for time-consuming sample preparation or chromatography. This approach enables data acquisition within minutes and supports high-throughput analysis.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Veri_Spray_Paper_Spray_Ion_Source_for_Mass_Spectrometry_ca9b0c1e64.jpg" alt="Thermo Scientific VeriSpray PaperSpray Ion Source for Mass Spectrometry" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Veri_Spray_Paper_Spray_Ion_Source_for_Mass_Spectrometry_ca9b0c1e64.jpg 245w," sizes="100vw" width="2020" height="552">The VeriSpray ion source is engineered for unattended, high-capacity operation, allowing the analysis of hundreds of samples with minimal manual intervention. By removing chromatographic steps, solvent consumption is reduced, instrument maintenance demands are lowered, and overall cost per test is significantly decreased.Fully integrated with <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=20&amp;manufacturerItems=3&amp;search=tsq">Thermo Scientific TSQ Series mass spectrometers</a>, the VeriSpray ion source is controlled through established software platforms, offering streamlined method setup, automated operation, and efficient data processing. This makes advanced mass spectrometric analysis accessible even in laboratories without extensive chromatography expertise.The VeriSpray PaperSpray Ion Source is particularly well suited for rapid quantitative analysis and screening applications in pharmaceutical, clinical, and research environments where speed, simplicity, and cost efficiency are essential.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Veri_Spray_Paper_Spray_Ion_Source_for_Mass_Spectrometry_2_31a0e60dd5.jpg" alt="Thermo Scientific VeriSpray PaperSpray Ion Source for Mass Spectrometry: For Research Use Only. Not for use in diagnostic procedures." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Veri_Spray_Paper_Spray_Ion_Source_for_Mass_Spectrometry_2_31a0e60dd5.jpg 171w," sizes="100vw" width="791" height="721"><h3>Key benefits and system integration</h3>The VeriSpray™ PaperSpray Ion Source improves turnaround time and reduces cost per test by eliminating chromatographic separation and minimizing sample preparation. Direct ionization enables one-step analysis of unprocessed samples, with MS results typically available in less than two minutes.Designed for high-throughput operation, the system supports unattended analysis of large sample batches and can be expanded with an optional automated plate loader for increased productivity. Proprietary VeriSpray PaperSpray sample plates are available for single-sample and high-throughput workflows, including barcoded formats to support automated sample tracking and integration with commercial robotic systems.The VeriSpray ion source is fully integrated into Thermo Scientific instrument control and application software, providing complete source control, predefined method templates, and streamlined data acquisition. Optional data analysis software further supports quantitative and screening applications in areas such as food safety, environmental analysis, clinical research, and forensic toxicology.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Veri_Spray_Paper_Spray_Ion_Source_for_Mass_Spectrometry_3_ec23b1733d.jpg" alt="Thermo Scientific VeriSpray PaperSpray Ion Source for Mass Spectrometry" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Veri_Spray_Paper_Spray_Ion_Source_for_Mass_Spectrometry_3_ec23b1733d.jpg 216w," sizes="100vw" width="540" height="390"><h3>Instrument compatibility</h3>The VeriSpray™ PaperSpray Ion Source is compatible with <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=20&amp;manufacturerItems=3&amp;search=tsq">Thermo Scientific TSQ triple quadrupole mass spectrometers</a>, including:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/404">TSQ Altis</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/414">TSQ Quantis</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/412">TSQ Fortis</a></li><li>TSQ Quantiva</li><li>TSQ Endura</li></ul><h3>Software support</h3><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1758">Thermo Scientific Xcalibur</a> instrument control and data acquisition software (version 4.3 SP1 or higher)</li><li>Full VeriSpray ion source control via method editor</li><li>Predefined method templates for VeriSpray workflows</li><li>Optional <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/77">Thermo Scientific TraceFinder </a>data analysis software (version 4.1 SP5 or higher)</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Veri_Spray_Paper_Spray_Ion_Source_for_Mass_Spectrometry_4_255b1d9010.jpg" alt="Thermo Scientific VeriSpray PaperSpray Ion Source for Mass Spectrometry" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Veri_Spray_Paper_Spray_Ion_Source_for_Mass_Spectrometry_4_255b1d9010.jpg 217w," sizes="100vw" width="650" height="467"><h3>Specifications</h3><ul><li>For Use With (Equipment): TSQ triple quadrupole MS</li><li>Height (Metric): 37.5 cm</li><li>Hertz: 50/60 Hz</li><li>Includes: Barcode reader for plate identification</li><li>Length (Metric): 15.25 cm</li><li>Weight (Metric): 10.7 kg</li><li>Width (Metric): 54 cm</li><li>Type: Ion Source</li><li>Unit Size: Each</li></ul>

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