In the lab, generating high-quality data is only half the challenge. Processing, reporting and reviewing that data efficiently and in a controlled manner is where the battle for cost-effectiveness and regulatory compliance can be won and lost. That’s why labs have Standard Operating Procedures (SOP) that outline how data should be analysed, reported and reviewed to ensure consistency, productivity and conformity.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Work_Smarter_Review_Faster_with_Chromeleon_CDS_cover_7f2444553e.jpg" alt="Thermo Fisher Scientific: Work Smarter, Review Faster with Chromeleon CDS" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Work_Smarter_Review_Faster_with_Chromeleon_CDS_cover_7f2444553e.jpg 244w," sizes="100vw" width="1600" height="1025">Thermo Scientific <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/76">Chromeleon Chromatography Data System (CDS)</a> provides a series of tools to aid data processing and reporting while ensuring adherence to regulatory and data integrity guidelines. It also includes another powerful tool, called View Settings, that help streamline and control data review by providing an easy way to walk reviewers through the various aspects of the data that should be examined.<h4>A smarter way to work</h4>One of the View Settings key capabilities is to allow users to configure and save custom collections of panes in the Chromeleon Chromatography Studio. Multiple View Settings files can be created and added to a sequence, each providing different views of the data so that every analyst, reviewer, or supervisor can interact with the data in a way that suits their role which may include emphasizing chromatograms, displaying calibration graphs, highlighting result tables, or presenting system suitability information. This tailored approach reduces time spent navigating between windows or searching for key metrics, enhancing focus, reducing cognitive load and improving accuracy.<h4>Guiding the review process step by step</h4>Beyond user customization, one of the most practical applications of View Settings is mapping them directly to each step of the SOP-driven review process. For many analysts, daily review involves repeating the same checks in the same order. With View Settings, each stage—like retention time verification, blank injection review, QC checks, and calibration curve validation—can have its own dedicated layout and the reviewer simply clicks between them.Each layout displays only the data required for that step, removing distractions and reinforcing SOP adherence. Clicking a peak in one pane instantly highlights related results in others, helping analysts quickly spot issues or trends.Out-of-specification results can also be flagged, allowing analysts to focus their attention where it’s needed most. This targeted approach helps streamline decision-making and reduces review time without compromising quality.<blockquote><a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/watch?v=eVlYCOzFiSg">Thermo Scientific Chromeleon CDS view settings</a>See how Chromeleon CDS enables users to create custom view settings to guide data review and ease training requirements</blockquote><h4>Consistency across the lab</h4>Beyond individual productivity, View Settings support lab-wide consistency. They can be saved, shared, and embedded in eWorkflow™ templates to standardize review processes across teams and sites. When procedures change, updated layouts can be rolled out with minimal disruption.They also simplify onboarding. New users can get up to speed faster, with pre-configured layouts, reducing complexity and cutting training time.<h4>Real benefits, every day</h4>So, what do labs gain from using View Settings?<ul><li>Faster data review, with only the data you need at each step</li><li>Reduced training time, thanks to guided, intuitive layouts</li><li>Fewer errors, as users follow structured review paths</li><li>Improved consistency, especially across large teams or global sites</li><li>Flexible control, with tools to update and deploy views centrally</li><li>Regulatory compliance, with easily documented steps and audit trails</li></ul><h4>Final thoughts</h4>As labs handle more data and complexity, tools that simplify the user experience aren’t optional — they’re essential. Chromeleon View Settings make data review faster, smarter, and more consistent. They might not be the flashiest feature — but in a well-run lab, they could be one of the most valuable.<h5>Want to learn more about time-saving features within Chromeleon software?</h5>Take a look at our <a target="_blank" rel="noopener noreferrer" href="https://event.on24.com/eventRegistration/EventLobbyServlet?target=reg20.jsp&amp;eventid=5017954&amp;sessionid=1&amp;key=370D77F31338CF6F6F92F8321937735E&amp;groupId=6227300&amp;sourcepage=register">Chromeleon knowledge byte webinar series</a> or visit the <a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/cz/en/home/industrial/chromatography/chromatography-learning-center/chromeleon-cds-information.html">Chromeleon university</a> for more how-to-videos.<blockquote><a target="_blank" rel="noopener noreferrer" href="https://www.linkedin.com/showcase/72003132/admin/dashboard/">Visit us on LinkedIn</a>: #Chromeleon #Software #LabProductivityZoe JulianZoe Julian is a Product Marketing Manager for Chromatography and Mass Spectrometry software at Thermo Fisher Scientific. With over 12 years' experience of working with chromatography and mass spectrometry techniques with a background in GC and GC-MS(/MS) organic environmental analysis, she has helped many laboratories and industries improve their workflows through a unique understanding of their challenges. Transitioning to a focus on Chromeleon CDS she has shown customers how software solutions can improve their productivity and support their day-to-day operations.</blockquote>

Work Smarter, Review Faster with Chromeleon CDS

In preparative chromatography there are three goals. How you balance these will dictate how you approach your scale up from analytical to preparative scale for large scale HPLC purifications.<h4>Part 1: Optimizing Separation</h4>In preparative HPLC there is a balance between purity, yield, and throughput, and often you must sacrifice one to achieve the other two. The three diagrams below show different outcomes depending on the purification objectives:<ul><li>Left: you could have a balanced triangle, where all three components are achieved, albeit none of these reach their maximum,</li><li>Middle: you could prioritize purity and yield at the cost of longer sample processing times, or</li><li>Right: you could prioritize sample processing speed and purity, sacrificing purification yield.</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Part_1_Optimizing_Separation_4767cb5f67.jpg" alt="Phenomenex: Part 1 - Optimizing Separation" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Part_1_Optimizing_Separation_4767cb5f67.jpg 245w," sizes="100vw" width="1425" height="487"><h4>Before you begin you would want to consider:</h4><ul><li>What is the required final purity?</li><li>Is the desired final product a specific salt form, a solid or a solution?</li><li>How can you balance processing time and yield?</li></ul>Once your objectives are outlined, a suitable analytical method must be established to evaluate purification conditions. Often a screening method is carried out to quickly evaluate large numbers of samples with key results confirmed by the full analytical method. During analytical screening multiple sets of conditions are typically tested to determine the most effective for preparative purification. Below we can see the effect of different solvent systems on the separation of two peaks required for preparative purification.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Part_1_Optimizing_Separation_peptides_68cd160f93.jpg" alt="Phenomenex: The effect of different solvent systems on the separation of two peaks required for preparative purification." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Part_1_Optimizing_Separation_peptides_68cd160f93.jpg 159w," sizes="100vw" width="853" height="838">Typically, with crude samples the impurities can lie close to the peak of interest. Although the desired resolution may be achieved analytically, it is important to ascertain, during the development process, how much of your sample you can load before resolution is lost. Shown below is an example of column screening for liraglutide where four stationary phases were screened under various conditions to ascertain optimal separation of impurities. Once you complete your screening you are able to select the most appropriate separation for scale up (covered in Part 2 - our next week's technical tip).<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Kinetex_C8_ae2ccb9d05.jpg" alt="Phenomenex: Kinetex C8 - comparison of different solvents" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Kinetex_C8_ae2ccb9d05.jpg 245w," sizes="100vw" width="1030" height="593"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Kinetex_C18_e8610074c5.jpg" alt="Phenomenex: Kinetex C18 - comparison of different solvents" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Kinetex_C18_e8610074c5.jpg 245w," sizes="100vw" width="1076" height="318"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Kinetex_phenyl_hexyl_eceef0e8d3.jpg" alt="Phenomenex: Kinetex phenyl-hexyl - comparison of different solvents" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Kinetex_phenyl_hexyl_eceef0e8d3.jpg 245w," sizes="100vw" width="1064" height="339"><h5>Preparative Chromatography meets UHPLC: Axia™ Packed Kinetex Columns</h5>The power of Kinetex core-shell technology with the performance of piston packed prep columns.<ul><li>Download brochure <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/br11940313_w_a1926e1f93.pdf">HERE</a></li></ul><h5>An Overview of Preparative Chromatography</h5><ul><li>Watch webinar<a target="_blank" rel="noopener noreferrer" href="https://discover.phenomenex.com/recorded-webinars-en"> HERE</a></li></ul>

What is the most appropriate way to approach scaling up your analytical method when transferring it to preparative chromatography scale? Part 1

News from LabRulezLCMS Library - Week 47, 2025

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DataApex Clarity Offline Chromatography Software

Clarity Offline allows users to import previously acquired data and to evaluate and prepare methods in regulated environment.

Clarity Offline allows users to import previously acquired data and to evaluate and prepare methods. This version cannot acquire data, but it can share data or even directly access (through LAN) projects of the <a href="https://lcms.labrulez.com/products/999">Clarity</a> and Clarity Lite software. With Clarity Offline users are able to work with acquired data on additional computers in the lab or at home. The software works with the same files and provides the same outputs (printing and exporting) as Clarity and Clarity Lite.
Clarity Offline is intended for use as additional software that supplements Clarity and Clarity Lite. It can also be used to evaluate data from other manufacturers&#39; CDS.
<blockquote>
Ask for <a href="https://www.dataapex.com/product/clarity-demo">Clarity Demo version</a> which allows you to get your hands on software before purchase
</blockquote>
<h3>Main features</h3>
<ul>
<li>21 CFR Part 11 compliance: Clarity Offline contains all functions (Electronic Signatures, User Accounts, Audit Trail, etc.) for compliance with the 21 CFR Part 11 directive of the FDA. Clarity Offline can be used for evaluation in regulated environments.
</li>
<li>Networked Solution: Clarity Offline can access files of Clarity and Clarity Lite installed on networked computers. This enables evaluation of chromatograms, development of new methods, and printing reports on additional computers in the laboratory.
</li>
<li>Education: An additional field of use is in education. Students can process chromatograms that have been acquired from Clarity connected to a chromatograph using their Clarity Offline license. Thus they do not need a Clarity full license just for data evaluation.
</li>
<li>Data processing and evaluation from other chromatography software: Clarity Offline allows the import of data from other chromatography software using text or AIA import function. This allows the user to process and evaluate chromatograms acquired by other chromatography software.
</li>
<li>Offsite computer: Clarity Offline can be installed on any Windows computer, giving you anytime access to your chromatographic data (USB hardware key is required).
</li>
<li>Language Localizations available: Useful for non-English speakers. At the moment, there are French, German, Russian, Spanish, and Chinese localizations available in a single installation package. Simply switch to your preferred language anytime.
</li>
</ul>
<a href="https://www.dataapex.com/controls">List of supported instruments</a>
<a href="https://www.dataapex.com/product/clarity-std-compatibility">Compatible Windows OS and Hardware</a>
<a href="https://www.dataapex.com/product/clarity-21cfr-compliance">Clarity 21 CFR Part 11 compliance</a>

DataApex PDA - Photodiode Array Extension for Clarity

The PDA Extension is an optional Extension that is used for processing data that has been acquired from selected photo diode array detectors. Spectral data, together with chromatograms, add a third dimension to analytical data analysis.

<h3>Extension for 3D data analysis from Photodiode Array Detectors</h3>
The PDA Extension is an optional Extension that is used for processing data that has been acquired from selected photo diode array detectors. Spectral data, together with chromatograms, add a third dimension to analytical data analysis. This extension expands the capability of <a href="https://lcms.labrulez.com/products/999">Clarity</a> by providing interactive spectral analysis, peak purity analysis and compound identification that is based on a spectral library search. PDA data can be displayed in a set of optional views including 3D rendering.
All data is saved in a single file; a chromatogram at any wavelength or even only a spectrum can simply be recalled for review after an analysis. UV-VIS spectra, acquired using a PDA detector, may be interactively selected from a chromatogram signal for visual inspection and comparison. The spectra may also be used for peak purity determinations, wavelength optimization and component identification through spectral libraries.
<h4>Main features</h4>
<ul>
<li>PDA View: The PDA view is customizable; up to four views can be displayed at one time (Any combination from the following views may be selected: Isoplot, Chromatogram, Spectra, 3D Display, Peak Purity, Peak Purity Spectra, Library Spectra Search and Spectral Library). The user can easily extract chromatographic signals from PDA data to determine the optimal detection wavelength for each peak.
</li>
<li>PDA Method: The Clarity PDA method includes an option for Spectral Library Search and Peak Purity analysis.
</li>
<li>Limit values: These calculated values are compared to user-set limit values, either for each chromatogram separately or together for the selected series. Deviation of a certain parameter from the permissible limits is immediately reported and may lead to the termination of the sequence in progress.
</li>
<li>Spectral Library: The Clarity software compares the peak spectra with the spectra of an unlimited number of spectral libraries. Spectra stored in a Spectral Library include retention times and analysis parameters (optional). The Spectral Library Search can perform automatic identification of integrated/calibrated components (peaks). The library search may be constrained by the RT Window and by Wavelength Range. Either the Least Square, the Weighted Least Square or the Correlation Method is used for calculating library search matches. A Background Correction option is also available.
</li>
<li>Peak Purity: This analysis helps to discover hidden impurities. Peak Purity test is applied to all integrated/calibrated peaks in the active signal. Purity is calculated from 5 or all spectra within the peak. The similarity curve is displayed in the PDA window. Peak Purity analysis can be optimized by setting custom preferences relating to the purity threshold, wavelength restriction and absorbance threshold.
</li>
<li>Import/Export Data: Spectral data can be imported/exported in ASCII text formats to or from the <a href="https://lcms.labrulez.com/products/999">Clarity software</a>.
</li>
<li>Reports: Users can easily include PDA options such as data 3D Display, Isoplot, Spectra, Peak Purity and Library Search results in reports using the intuitive Report Setup Dialog.
</li>
<li>Instrument Control: Control modules for Agilent 1100 DAD and FLD, Sykam S3210/3240, Knauer PDA and many others are available. Additional control modules for other PDA detectors can be developed upon request.
</li>
</ul>
<a href="https://www.dataapex.com/controls#9709a8ca9130f20fc18c284302efd33b">List of controlled PDA detectors</a>

DataApex SST - System Suitability Test Extension for Clarity

The SST extension serves to monitor the correct function of the chromatography system. The program compares up to 12 selected parameters (e.g., retention time, efficiency, asymmetry of peaks) calculated according to one of three pre-selected methods (USP, EP, JP).

<h3>The SST extension serves to monitor the correct function of the chromatography system.</h3>
The program compares up to 12 selected parameters (e.g., retention time, efficiency, asymmetry of peaks) calculated according to one of three pre-selected methods (USP, EP, JP). These calculated values are either compared to the user&#39;s set limit values for each chromatogram separately or together for the selected series. Deviation of any parameter from the permissible limits is immediately reported and may lead to the termination of the sequence in progress. The SST Extension allows the user to monitor the parameters of individual substances and thus evaluate the reproducibility of the results of the entire chromatography system.
The SST extension is required when using the <a href="https://www.dataapex.com/product/validation-kit">Validation Kit</a>.
<h3>Main features</h3>
<ul>
<li>Measuring: Simultaneous data acquisition from up to four signals (detectors) attached to one chromatograph.
</li>
<li>Parameters: The program compares up to 12 selected parameters (e.g., retention time, efficiency, asymmetry of peaks) calculated according to one of three pre-selected methods (USP, EP, JP).
</li>
<li>Limit values: These calculated values are compared to user set limit values, either for each chromatogram separately or together for the selected series. Deviation of a certain parameter from the permissible limits is immediately reported and may lead to the termination of the sequence in progress.
</li>
<li>Versatility: Even though validation primarily focuses on testing system reliability, it can also be used in many other ways. Validation can be run during measurements, or additionally, using batch processing. Validated data can be automatically saved to a database file for further processing.
</li>
<li>Enhanced sequencing: In connection with a sequence, the SST module can even pause a sequence when a specified value has been exceeded or to perform predefined functions.
</li>
</ul>
<a href="https://gcms.labrulez.com/products/999">Clarity</a> Chromatography Software required

DataApex MS - Mass Spectrometry Extension for Clarity

The Clarity MS Extension is a tool that is used for processing data that has been acquired from selected Mass Spectrometry detectors. Spectral data, together with chromatograms, add a third dimension to analytical data analysis.

<h3>Clarity Extension for processing data that has been acquired from selected Mass Spectrometry detectors</h3>
The Clarity MS Extension is a tool that is used for processing data that has been acquired from selected Mass Spectrometry detectors. Spectral data, together with chromatograms, add a third dimension to analytical data analysis.
The MS Extension expands the capability of <a href="https://lcms.labrulez.com/products/999">Clarity</a> and <a href="https://lcms.labrulez.com/products/1000">Clarity Offline</a> Chromatography software by providing interactive spectral analysis, peak purity analysis, and compound identification that is based on a spectral <a href="https://gcms.labrulez.com/products?category=249">library</a> search. The extension is prepared to function with single quadrupole MS detectors and TOF MS detectors.
All data is saved in a single file; a chromatogram at any m/z value or even only a spectrum can simply be recalled for review after an analysis. MS spectra, acquired using an MS detector, may be interactively selected from a chromatogram signal for visual inspection and comparison. The spectra may also be used for peak purity determinations and component identification through spectral <a href="https://lcms.labrulez.com/products?category=285">libraries</a>.
It is possible to import MS data in AIA (cdf), mzXML, MzML, and mzData formats.
Control modules for selected detectors (see <a href="https://www.dataapex.com/controls">list of control modules</a>) are available in Clarity. Additional control modules for MS detectors can be developed upon request.

DataApex GPC - Gel Permeation Chromatography Extension for Clarity 

GPC Extension provides interactive and automated GPC analysis, including recalibration and GPC reporting, as well as simplifies the retrieval of GPC data. The GPC Extension allows flow rate and multi-detector delay corrections and includes Narrow, Broad, and Broad on Narrow calibrations.

<h3>Extension provides interactive and automated GPC analysis, including recalibration and GPC reporting, as well as simplifies the retrieval of GPC data.</h3>
Gel Permeation Chromatography (GPC) / Size Exclusion Chromatography (SEC) is the technique used for obtaining a rapid and reliable characterization of polymer molecular weight and molecular weight distribution. GPC Extension provides interactive and automated GPC analysis, including recalibration and GPC reporting, as well as simplifies the retrieval of GPC data. The GPC Extension allows flow rate and multi-detector delay corrections and includes Narrow, Broad, and Broad on Narrow calibrations.
<h3>Main features</h3>
<ul>
<li>Data Acquisition: Simultaneous data acquisition from up to four four-detector chromatographs (4×4 configuration), detector delay correction for multidetector measurement. 
</li>
<li>Data Processing: The same chromatograms can be evaluated in both standard and GPC modes. Multiple peaks and multiple signals are processed in one chromatogram.
</li>
<li>GPC Integration: Separate integration tables for GPC and standard evaluation are used. There are extensive possibilities for modifying chromatograms. The chromatogram integration can be changed by entering global parameters or interactively, through the direct graphical modification of the baseline.
</li>
<li>Calibration: Narrow, Broad, Broad on Narrow standard calibration methods combined with Flow Rate correction and Universal calibration. Manual calibration or automated recalibration from a sequence. Multiple Broad standards can be used.
</li>
<li>GPC Calculations: Polynomial (n= 1-5) curve fits (independent for signals), Mp, Mn, Mw, Mv, Mz, Mz+1 molecular weight averages and polydispersity.
</li>
<li>Graphs: Molecular weight distribution graphs. Overlay: Simultaneously displays a virtually unlimited number of chromatograms. Overlay of dW/d logM vs. log M and cumulative height graphs.
</li>
<li>Export: Slice Table results, graphs, result and summary tables.
</li>
<li>User Calculations: Users can define custom calculations in the Result and Summary tables. Using the integrated editor, you can create your own columns from the original columns and individual mathematical functions.
</li>
<li>GPC Results Table: Displays molecular weight averages together with peak details for active signal. Multiple peaks can be evaluated from one chromatogram.
</li>
<li>GPC Summary Result Tables: Displays and prints selected results from all simultaneously displayed chromatograms. Postrun: Automatically displays, prints, exports, and starts other programs after the completion of a measurement.
</li>
<li>Batch: Automatically batch processes, displays, exports, or prints any number of chromatograms.
</li>
<li>Reports: User selectable report sections and WYSIWYG formating of Graphs and Tables.
</li>
</ul>

DataApex CE - Capillary Electrophoresis Extension for Clarity

CE module provides specific terminology, evaluation by time corrected area and peak identification by peak start or end (additionally to peak apex).

<h3>Extension for Capillary Electrophoresis</h3>
The CE Extension activates the CE mode in Clarity environment and can be activated on any <a href="https://lcms.labrulez.com/products/999">Clarity</a> Instrument. CE Extension is compatible also with <a href="https://lcms.labrulez.com/products/1000">Clarity Offline</a> software. CE module provides specific terminology, evaluation by time corrected area and peak identification by peak start or end (additionally to peak apex).
<h4>Main changes in Clarity environment</h4>
<ul>
<li>CE specific terminology</li>
<li>Evaluation by time corrected area</li>
<li>Peak identification by peak start or end (additionally to peak apex).</li>
<li>Additional calculations</li>
</ul>
<h4>CE specific terminology</h4>
The terms used in chromatography mode were substituted by those used in CE:
<ul>
<li>Default mode =&gt; CE mode</li>
<li>Chromatogram =&gt; Electropherogram</li>
<li>Retention time (RT) =&gt; Migration Time (MT)</li>
<li>Column =&gt; Capillary</li>
<li>Mobile Phase =&gt; Electrolyte</li>
<li>Flow Rate =&gt; Power supply</li>
<li>Pressure =&gt; Injection Mode</li>
</ul>
<h4>Separation parameters</h4>
Method Setup allows a user to adjust the Capillary Setting:
<ul>
<li>Total Capillary Length</li>
<li>Length of the capillary.</li>
<li>Effective Capillary Length</li>
<li>Effective capillary length from injection end to the detector position</li>
<li>Separation Voltage</li>
<li>Separation voltage. Allows you to enter also negative values</li>
<li>Reference Peak Mobility</li>
<li>Effective mobility of the EOF reference peak.</li>
</ul>
<h4>Calculations</h4>
The Result Table contains additional columns containing calculations:
<ul>
<li>Apparent Mobility</li>
<li>Effective Mobility</li>
</ul>

DataApex Clarity Chromatography Software

Clarity is a chromatography data software for data acquisition, processing, and instrument control in regulated environment. Clarity is a flexible solution for devices from different vendors, supporting different applications.

Optional control modules provide integrated control of selected instruments such as GCs, LCs, pumps, detectors, autosamplers, etc. Extensions provide functions for specific separation techniques or calculations such as PDA, GPC analysis, Mass spectrometry, or SST. Clarity can run in English, French, German, Russian, Spanish, and Chinese language. Support technicians and developers are close to their users and ready to provide extensive Support from DataApex.
<blockquote>
Ask for <a href="https://www.dataapex.com/product/clarity-demo">Clarity Demo version</a> which allows you to get your hands on software before purchase
</blockquote>
<h3>Main features</h3>
<ul>
<li>Measuring: Simultaneous data acquisition from up to four independent chromatographs, each chromatograph can acquire data from up to 32 detectors.
</li>
<li>Integration: There is an extensive possibility to modify chromatograms. The chromatogram can be changed by entering global parameters or interactively through direct graphic modification of the baseline.
</li>
<li>Overlay: Simultaneously displays a virtually unlimited number of chromatograms and their mathematical modification; for example, mutual deductions or derivations of any order.
</li>
<li>Calibration: Internal and external standard calculation methods, calibration of groups of peaks, and reference peaks method for better identification.
</li>
<li>Wide range of supported instruments: Control modules in Clarity allow users to control various instruments in their lab. See our growing <a href="https://www.dataapex.com/controls">List of supported instruments</a>.
</li>
<li>Extensions completing your workflow: Clarity Extensions integrates your workflow into one application. GPC calculations, PDA data processing, gas or detailed hydrocarbon analyses according to selected norms, and much more.
</li>
<li>Automated measuring support: Sequence tables for any set of samples with or without an autosampler.
</li>
<li>Postrun: Automatically displays, prints, exports, and starts other programs after the completion of a measurement.
</li>
<li>Summary result tables: Displays and prints selected results from all simultaneously displayed chromatograms.
</li>
<li>User settings: User selects parameters for peak display and the specification for axes, including color from an extensive array of color settings. Text labels and lines, either as part of the area or anchored to a chromatogram, may also be inserted.
</li>
<li>Export: Optional exportation of all results, with or without the chromatogram, in various formats, into a file or clipboard.
</li>
<li>Import: Imports chromatograms or mathematical curves, which have been saved in text or AIA formats, from other programs.
</li>
<li>LIMS: Clarity offers connectivity with LIMS, both for sample submission and result output. This can be done via convenient ASCII transfers.
</li>
<li>Method and calibration history: Each chromatogram can easily be displayed under the same conditions as when it was printed, exported, or saved.
</li>
<li>Column performance: Calculations of peaks in terms of symmetry, efficiency, resolution; all by several methods (tangent, moments, etc.).
</li>
<li>Batch: Automatically batch processes, displays, exports, or prints any number of chromatograms.
</li>
<li>User calculations: Users can define custom calculations in the Result and Summary tables. Using the integrated editor, you can create your own columns from original columns and individual mathematical functions.
</li>
<li>User accounts: Sets up access rights and passwords (including their parameters, e.g., minimum length, validity, etc.). Each user can define his or her own appearance of the software.
</li>
<li>Audit trail: Records selected events and operations into a special file. Records selected operations directly into a chromatogram.
</li>
<li>Electronic signature: Each chromatogram can be signed electronically. Signature selection is based on the username or the signature certificate.
</li>
<li>Networked Solution: Clarity chromatography software files can be accessed from networked computers using Clarity Offline software. This enables the offline evaluation of chromatograms, development of new methods, and printing reports. See the <a href="https://gcms.labrulez.com/products/1000">Clarity Offline</a> for more details.
</li>
<li>Language Localizations available: Useful for non-English speakers. At the moment, there are French, German, Russian, Spanish, and Chinese localizations available in a single installation package. Simply switch to your preferred language anytime.
</li>
<li>Competitive approach: The chromatography market offers many specialized HPLC data systems or GC data systems; these are often provided with the purchased instrument. It is usually complicated to integrate such software into the workflow of the laboratory since they do not enable direct control of additional instruments. Compared to other small-scale solutions, Clarity offers a wide range of directly controlled instruments as well as optional Extensions for specific separation techniques. On the other hand, complex solutions with a wide scope of features and scalable design are quite expensive, which is a limiting factor for many customers. Another drawback of the large solutions is their complexity which imposes high demands on users. Compared to this, Clarity represents a scalable medium-ranged solution with a steep learning curve and competitive prices.
</li>
</ul>
<h3>Clarity configurations examples</h3>
<h4>One chromatograph with two detectors</h4>
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Clarity_Chromatograficky_Software_Clarity_configurations_examples_One_chromatograph_with_two_detectors_ae482b83b8/DataApex-Clarity-Chromatograficky-Software-Clarity-configurations-examples-One-chromatograph-with-two-detectors.jpg" alt="DataApex Clarity Chromatography Software: Clarity configurations examples - One chromatograph with two detectors.jpg"/>
<ul>
<li>The HPLC measures on two detectors. Clarity will acquire two separate signals sharing a common timebase (synchronized START/STOP). A resulting chromatogram will contain two signals.</li>
</ul>
<h4>Two chromatographs, one with multiple detectors</h4>
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Clarity_Chromatograficky_Software_Clarity_configurations_examples_Two_chromatographs_one_with_multiple_detectors_b21dc07faf/DataApex-Clarity-Chromatograficky-Software-Clarity-configurations-examples-Two-chromatographs-one-with-multiple-detectors.jpg" alt="DataApex Clarity Chromatography Software: Clarity configurations examples - Two chromatographs, one with multiple detectors.jpg"/>
<ul>
<li>This example displays a configuration with two chromatography systems (GC + HPLC) where the HPLC system uses multiple detectors. All the detectors attached to the HPLC Instrument will share common timebase (synchronized START/STOP). The GC detector will be independent.</li>
</ul>
<h4>Two chromatographs, one digital control</h4>
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Clarity_Chromatograficky_Software_Clarity_configurations_examples_Two_chromatographs_one_digital_control_1bf9cec334/DataApex-Clarity-Chromatograficky-Software-Clarity-configurations-examples-Two-chromatographs-one-digital-control.jpg" alt="DataApex Clarity Chromatography Software: Clarity configurations examples - Two chromatographs, one digital control.jpg"/> This example displays a configuration with two chromatography systems (GC + LC). The GC is connected and controlled via digital interface *, using a GC Control appropriate module.
<h4>Four chromatographs with autosampler each</h4>
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Clarity_Chromatograficky_Software_Clarity_configurations_examples_Four_chromatographs_with_autosampler_each_945873d808/DataApex-Clarity-Chromatograficky-Software-Clarity-configurations-examples-Four-chromatographs-with-autosampler-each.jpg" alt="DataApex Clarity Chromatography Software: Clarity configurations examples - Four chromatographs with autosampler each.jpg"/>
<ul>
<li>This example displays a configuration with two chromatography systems (GC + LC). The GC is connected and controlled via digital interface *, using a GC Control appropriate module.</li>
</ul>
<a href="https://www.dataapex.com/controls">List of supported instruments</a>
<a href="https://www.dataapex.com/product/clarity-std-compatibility">Compatible Windows OS and Hardware</a>
<a href="https://www.dataapex.com/product/clarity-21cfr-compliance">Clarity 21 CFR Part 11 compliance</a>

Products from DataApex - page 1

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