<h5>Why compromise between performance and price when you can have both?</h5>With Thermo Scientific factory-certified, pre-owned <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=5&amp;manufacturerItems=3">mass spectrometers</a>, you can access legendary LC-MS technology—trusted around the world—at a fraction of the cost of buying new. Our refurb program delivers the quality, precision, and reliability you expect from Thermo Fisher Scientific, while helping you stay within budget and on top of your analytical goals.<h3>Factory-Certified for confidence</h3>Every certified pre-owned system goes through a rigorous factory reconditioning process. From updated hardware and software to comprehensive performance testing, each instrument is restored to meet the same high standards as our new products.<h4>What’s included?</h4>When you choose a certified LC-MS system, you get more than just an instrument—you get the complete Thermo Scientific experience:<ul><li>Full 1-year factory warranty for peace of mind</li><li>29-point inspection checklist, re-certification, and final quality testing</li><li>Software and hardware updates to current revisions</li><li>Re-certification using only genuine Thermo Scientific factory parts</li><li>Professional installation by Unity Lab Services field engineers</li><li>Optional training and application support to get you up and running fast</li></ul><h4>What gets replaced?</h4>Our reconditioning process is comprehensive. These critical components are replaced on every system:<ul><li>All hoses</li><li>Probes</li><li>Ion sources</li><li>Ion transfer tube</li><li>Multiplier</li><li>Mechanical pumps</li><li>Acquisition PC and software</li><li>PCBs (when required for revision)</li></ul><h3>Maximize uptime with expert support</h3>Behind every certified system is a global team of Thermo Fisher specialists committed to helping your lab succeed. Support doesn’t stop after installation:<ul><li>Flexible service contract options through Unity Lab Services</li><li>Guaranteed response times for select contracts</li><li>Financing solutions to meet your budget</li><li>System qualifications and validations</li><li>Technology refresh solutions to keep you ahead of the curve</li></ul><h3>A smarter, more sustainable choice</h3>Investing in a factory-certified pre-owned system isn’t just cost-effective—it’s a sustainable solution that extends the life of high-performance equipment and reduces waste. You get the data quality and instrument reliability your work depends on, while making an environmentally conscious choice.<h3>More ways to access Thermo Scientific excellence—affordably</h3>We understand that every lab’s financial situation is different. That’s why Thermo Fisher offers multiple paths to help you acquire the right mass spectrometry solution, when you need it.<h4>1. <a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/content/lifetech/global/en/home/industrial/mass-spectrometry/mass-spectrometer-price-affordability-programs/factory-certified-refurbished-mass-spectrometers.html">Factory-certified refurbished systems</a></h4>Already covered above, this option gives you fully reconditioned, factory-tested LC-MS instruments at a lower price point—without compromising performance or support.View our brochure for a comprehensive overview.<h4>2. <a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/content/lifetech/global/en/home/industrial/mass-spectrometry/mass-spectrometer-price-affordability-programs/mass-spectrometer-trade-upgrade.html">Trade-in and trade-up</a>: Turn your old into increased productivity</h4>Already own a system—Thermo Fisher or otherwise? Trade it in and upgrade to a newer model with greater capabilities and sensitivity.How it works:<ul><li>Receive a discount on your next system based on the residual value of your current instrument</li><li>Avoid the hassle of selling or decommissioning your old system</li><li>Transition with minimal downtime and disruption</li></ul>Why labs choose this path:<ul><li>Keeps productivity high while moving to new technology</li><li>Eases the financial burden of upgrading</li><li>Helps labs stay competitive with improved system performance</li></ul><h4>3. Personalized equipment <a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/content/lifetech/global/en/home/products-and-services/services/financial-leasing-services.html">financing &amp; leasing options</a></h4>If upfront capital is limited, our tailored financing and leasing plans offer flexibility that aligns with your lab’s budget and growth plans.<h5>Ready to get started?</h5><ul><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/content/lifetech/global/en/home/industrial/mass-spectrometry/mass-spectrometer-price-affordability-programs.html">Explore our certified systems, trade-in opportunities, and financing solutions.</a></li></ul>Visit us on&nbsp;<a target="_blank" rel="noopener noreferrer" href="https://www.linkedin.com/showcase/72003132/admin/dashboard/">LinkedIn:</a>&nbsp;#affordabiliy #LCMS #sustainability #productivity<blockquote><h5>Ema Ruzic</h5>Vertical Marketing Manager, Chromatography and Mass Spectrometry Division (CMD)</blockquote>

Unlock High-Performance LC-MS with Factory-Certified Systems from Thermo Fisher Scientific

Metalloproteins play essential roles in marine phytoplankton, yet their metalloproteomes remain poorly characterized. This study combines protein modeling, quantitative proteomics, and ICP-MS measurements to assess metal requirements across several phytoplankton species, including chlorophytes, a haptophyte, and a cyanobacterium.Results show strong agreement between proteome-inferred metal demands and measured cellular metal quotas, while providing deeper insight into biological functions. Mg-containing proteins were most abundant overall, with Zn, Fe, and Mn as dominant trace cofactors. Distinct differences between prokaryotic and eukaryotic phytoplankton were observed, and strain-level analysis demonstrated how metalloproteomes reflect environmental adaptation and metal limitation strategies.<blockquote><h4>The original article</h4><h4><a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acs.est.5c11233">Unlocking Phytoplankton Metallomes with Comparative Analysis of Metal Quotas, Quantitative Proteomics, and Inferred Metalloproteomes</a></h4>Qiong Zhang*, Jiayou Ge, Fengjie Liu, Shabaz Mohammed, Kedong Yin, and Rosalind E. M. RickabyEnviron. Sci. Technol. 2025, 59, 50, 27367–27377<a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1021/acs.est.5c11233">https://doi.org/10.1021/acs.est.5c11233</a><h6>licensed under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/">CC-BY 4.0</a></h6></blockquote>Selected sections from the article follow. Formats and hyperlinks were adapted from the original.Many important biological processes of phytoplankton, including photosynthesis, carbon fixation, and nitrogen reduction, rely on enzymes that have metals as cofactors. <a href="javascript:void(0);">(1)</a> It has been estimated that half of all enzymes must be associated with a particular metal to function. <a href="javascript:void(0);">(2)</a> The availability of metals in the environment has changed over geological time and, given imperfections in the selectivity of metal transport systems, proteins have evolved to make the best use of metals that are more available. <a href="javascript:void(0);">(3−5)</a> Depending on their evolutionary histories, different groups of marine phytoplankton may have differences in their metalloprotein compositions and metal transport strategies. The evolving trace metal availability in the environment, thus, may provide a selective pressure to promote the proliferation of different phytoplankton groups in the oceanic environment, affecting the phytoplankton community structure with knock-on effects on the marine food web and carbon sequestration. <a href="javascript:void(0);">(5)</a> It is crucial to understand the utilization of trace metals by different groups of marine phytoplankton that inhabit contrasting niches in the modern ocean, not only by assessing the accumulation of trace metals in cells but also examining the functions of trace metals in different biological pathways.In previous studies, the utilization or requirements of trace metals by marine phytoplankton were mostly determined by measuring the elemental stoichiometry in cells (metallome or quota of trace metals). <a href="javascript:void(0);">(6−8)</a> In the field, attempts have also been made to investigate the elements in phytoplankton <a href="javascript:void(0);">(9,10)</a> which have then been compared with profiles in the abiotic environment to understand their relationships. <a href="javascript:void(0);">(11)</a> The discovery of various metal storage proteins and the plasticity in elemental quotas under different environmental conditions raise the question of whether intracellular trace metal quotas reflect true differences in trace metal usage by phytoplankton. <a href="javascript:void(0);">(12,13)</a> In the past few decades, more and more studies have focused on metal–protein partnerships, using approaches such as genome-wide analysis to identify homologues of known metalloproteins and other deduced metal-binding motifs encoded within sequenced genomes. <a href="javascript:void(0);">(5,14)</a> However, this approach has limitations in estimating metal abundance in cells because not all genes predicted in the genome would be translated and expressed as proteins under all environments, and a single gene for a metalloprotein could be highly expressed, such that a translation from genetic presence to a required concentration is not linear and could be environment-dependent. To obtain in situ metal abundance in metalloproteins in cells, native separation of proteins by HPLC or PAGE followed by the detection of metals using ICP-MS <a href="javascript:void(0);">(15,16)</a> has been used. This approach also has limitations in that, without bioinformatics, it cannot identify the function of proteins within which the metals are found, and it may also depend on the composition of the media to which the organism has been exposed and in which it has been growing. An ideal way to solve the problem would be to separate and purify each of the proteins and then identify both the associated metal (e.g., by ICP-MS) and the protein sequence (e.g., by mass spectrometry). However, this approach is constrained by the resolution of chromatographic or electrophoretic techniques, making it challenging to establish the metal–protein associations unambiguously; many proteins often co-occur in metal-containing fractions. Additionally, this method requires huge volumes of biomass and is both time-consuming and complex, complicating the reconstruction of the expressed metalloproteome in cells. The techniques and challenges for metalloproteomics have been discussed in detail in previously published review articles (and the references therein). <a href="javascript:void(0);">(17)</a>In this study, we determined the trace metal utilization (the metallome) of different phytoplankton from their expressed proteome via a protein modeling and homologue identification approach, and then compared the resulting metallome with the metal quota data measured by the traditional inductively coupled plasma mass spectrometry (ICP-MS). This approach allows the building of a link between the truly used trace elements and their biological functions in phytoplankton. We aim to fill the gap between an estimation of metals encoded in the genome and metal analysis by ICP-MS in phytoplankton, which may be more broadly applicable to infer cellular metallomes.<h3>Materials and Methods</h3><h4>ICP-MS Analysis</h4>All preparation of samples for ICP-MS measurement was undertaken using trace metal clean methods. All plasticware used in this study, including culture flasks, pipette tips, and centrifuge tubes, was precleaned in 10% quartz-distilled HCl and thoroughly rinsed with 18 MΩ cm water in a clean laboratory. Trace elements in the filtered lysates of G. huxleyi (OA1, OA4, OA8, OA15, OA16, OA23, and RCC 1242) and Synechocystis (FACHB898) strains were measured using an ICP-MS. The detailed ICP-MS method and instrumental settings are described in Zhang et al. (2018). <a href="javascript:void(0);">(31)</a><h4>Protein Mass Spectrometry</h4>The peptides were resuspended in 5% formic acid and 5% DMSO prior to mass spectrometry. They were separated on an <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library?mainauthorItems=3&amp;search=Ultimate+3000+UHPLC">Ultimate 3000 UHPLC </a>system (Thermo Fisher Scientific) and electrosprayed directly into a <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/559">Q-Exactive Mass Spectrometer</a> (Thermo Fisher Scientific) through an EASY-Spray nanoelectrospray ion source (Thermo Fisher Scientific). The peptides were trapped on a C18 PepMap100 precolumn (300 μm i.d. × 5 mm, 100 Å, Thermo Fisher Scientific) using solvent A (0.1% formic acid in water) at a pressure of 500 bar. The peptides were separated on an in-house packed analytical column (75 μm i.d. × 50 cm packed with ReproSil-Pur 120 C18-AQ, 1.9 μm, 120 Å, Dr. Maisch GmbH) using a linear gradient (length: 65 min, 15% to 35% solvent B [0.1% formic acid in acetonitrile], flow rate: 200 nL/min). The raw data were acquired on the mass spectrometer in a data-dependent mode (DDA). Full scan MS spectra were acquired in the Orbitrap (scan range 350–1500 m/z, resolution 70000, AGC target 3e6, maximum injection time 50 ms). After the MS scans, the 10 most intense peaks were selected for HCD fragmentation at 30% of normalized collision energy. HCD spectra were also acquired in the Orbitrap (resolution 17500, AGC target 5e4, maximum injection time 120 ms, isolation window 1.5 m/z) with the first fixed mass at 180 m/z. Charge exclusion was selected for unassigned and 1+ ions. The dynamic exclusion was set to 20 s.<h3>Results and Discussion</h3><h4>Trace Elements Determined from the Expressed Proteomes of Different Phytoplankton</h4>Based on the expressed proteome sequences, we predicted metal-binding proteins and compared their distribution among various phytoplankton species (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acs.est.5c11233#fig2">Figure 2</a>). The inference revealed 28 different metals in G. huxleyi, 31 different metals in C. reinhardtii, and 30 different metals in Synechocystis. Although only 6 different metals were identified in O. tauri proteins, it has to be noted that the analysis for O. tauri was only based on the 40 most abundant proteins reported in this organism <a href="javascript:void(0);">(21)</a> and, hence, the listed elements, including Mg, Fe, Mn, Ca, Zn, and Cu, may represent the most essential metals for the species.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Environ_Sci_Technol_2025_59_50_27367_27377_Figure_2_The_number_of_metal_binding_proteins_identified_in_the_expressed_proteome_of_the_haptophyte_G_9b8ac0f004.jpeg" alt="Environ. Sci. Technol. 2025, 59, 50, 27367–27377: Figure 2. The number of metal-binding proteins identified in the expressed proteome of the haptophyte G. huxleyi (a), the chlorophyte C. reinhardtii (b) and O. tauri(c), and the cyanobacteria Synechocystis (d). Pie charts show the percentages of metalloproteins containing specific metals. Original proteome data for G. huxleyi are from Mckew et al. (2013) (24) for C. reinhardtii are from Hsieh et al. (2013) (77) for O.tauriare from Martin et al. (2012) (21) for Synechocystisare from Chen et al. (2018). (22) *Noted that for O. tauri, only the 40 most abundant proteins were included in this analysis. ND: no metal binding was found in the proteins." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Environ_Sci_Technol_2025_59_50_27367_27377_Figure_2_The_number_of_metal_binding_proteins_identified_in_the_expressed_proteome_of_the_haptophyte_G_9b8ac0f004.jpeg 123w," sizes="100vw" width="934" height="1181">The number of proteins that bind with different metals varies dramatically in phytoplankton. For metalloproteins, there are variations in the binding affinities of different metals to organic molecules. For example, the affinities of divalent metals to proteins have a tendency to follow a universal order of preference, namely the Irving-Williams series (Mg2+ and Ca2+ [weakest binding] &lt; Mn2+ &lt; Fe2+ &lt; Co2+ &lt; Ni2+ &lt; Cu2+ &gt; Zn2+). <a href="javascript:void(0);">(43)</a> Cells can simultaneously contain proteins having high-affinity-binding metals, such as Cu and Zn, and others that require uncompetitive metals, such as Mg and Ca. One of the least competitive metals for binding with biological chelators, Mg, is even found to be the most widely distributed metal in the metalloproteomes of various phytoplankton species in this study, supporting the observations of high concentrations in the protein fraction of cells (at millimolar concentrations <a href="javascript:void(0);">(31)</a>).In all phytoplankton species in our analysis, the Mg-containing proteins are found to have the highest proportion in all metalloproteins identified. About 30% of the metalloproteins in different strains of phytoplankton are found to contain Mg or depend on it for function (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acs.est.5c11233#fig2">Figure 2</a>), suggesting the important role of Mg in phytoplankton cells. It is generally coordinated in protein complexes by ATP or ADP and has also been found to be largely distributed in the chloroplasts or thylakoids in G. huxleyi and Synechocystis. <a href="javascript:void(0);">(22,24)</a> The essential roles of Mg in plants have been reported in various studies. Mg2+ is known to be the central atom of the chlorophyll molecule, and its levels in the chloroplast regulate the activity of key photosynthetic enzymes. <a href="javascript:void(0);">(44)</a> It was reported that approximately 15–35% of total Mg is in the chloroplasts of a plant, <a href="javascript:void(0);">(45)</a> and it also serves as an osmotically active ion in the regulation of cells <a href="javascript:void(0);">(46)</a><h4>Comparison Between Metallome Measured Directly and Reconstructed from Proteins</h4>A large proportion of metals, such as Fe, Mn, and Cu, are found in membrane proteins,and may contribute significantly to total cellular quotas. <a href="javascript:void(0);">(54,55)</a> However, for method development purpose, we endeavored to remove the cell membranes from our samples to focus mostly on the analysis of intracellular metal quotas and metalloproteins in the cytosol fraction in this study. We note that our analysis includes some membrane-bound proteins likely derived from organelles or surface membranes disrupted during sonication.The derivation of cellular metal composition, as determined by two different methods, is compared in <a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acs.est.5c11233#fig3">Figure 3</a>. The abundance of metal in the proteins is determined as the relative abundance of the protein multiplied by the number of metal ions needed for the specific protein. The abundance of the proteins was normalized to ensure that the total intensities from each replicate measurement for the same species were similar. Since the proteomic data used here were generated from different studies using different instruments, we cannot quantify or compare the absolute biomass of proteins used for each species. Therefore, we cannot compare the absolute trace metal abundance between species solely from metal inferences of expressed proteomes. Nevertheless, we can estimate the relative abundance of different metals in the same species. For the elements that are both measured by the ICP-MS and identified in the proteome, there are generally good correlations (r2 = 0.81 in <a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acs.est.5c11233#fig3">Figure 3</a>a and r2 = 0.74 in <a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acs.est.5c11233#fig3">Figure 3</a>b) between the two approaches. This indicates that the metal compositions determined from the protein modeling may be reliable and, therefore, can reflect the metal usage in different phytoplankton. This would provide a level of assurance to further investigate the metal binding associated with various proteins, thereby deepening our understanding of the roles that different metals play in phytoplankton.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Environ_Sci_Technol_2025_59_50_27367_27377_Figure_3_Relationship_between_the_abundance_of_metals_determined_by_ICP_MS_analysis_e7b259e376.jpeg" alt="Environ. Sci. Technol. 2025, 59, 50, 27367–27377: Figure 3. Relationship between the abundance of metals determined by ICP-MS analysis (normalized to C, mmol/mol C) and metal abundance determined from the metalloproteome analysis (the unit is arbitrary). To account for strain variations, the ICP-MS data for the cellular metal content of G. huxleyi are average values from 7 G. huxleyi strains isolated from different areas of the ocean, and the proteome-derived metal composition data are average values calculated from 2 of those G. huxleyi strains (OA1 and OA16) isolated previously, and data from Mckew et al., 2013. (24) The ICP-MS data for Synechocystis are from Synechocystis sp. FACHB898 measured in this study, and the proteome data are calculated from Chen et al., 2018. (22) Noted that the abundance of metals from each proteome was calculated by using the metal stoichiometry multiplied by the relative abundance of proteins, which provides only a relative relationship of different trace metals, not absolute abundance. The symbols represent the mean values, and the error bars indicate standard deviations." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Environ_Sci_Technol_2025_59_50_27367_27377_Figure_3_Relationship_between_the_abundance_of_metals_determined_by_ICP_MS_analysis_e7b259e376.jpeg 245w," sizes="100vw" width="1384" height="641">Compared to the other metals investigated in this study, Ca and Mg appear to have a much higher relative abundance in the ICP-MS analysis than in the proteomic analysis of G. huxleyi and Synechocystis (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acs.est.5c11233#fig3">Figure 3</a>). These two elements are essential macronutrients for phytoplankton and plants. Ca is the most prominent secondary messenger that plays a crucial role in response to extracellular stimuli in all eukaryotes. Ca2+ fluxes are transported via Ca channels and transporters, such as Ca-ATPase, regulating a series of important biological functions, including mineral uptake and utilization, K+ homeostasis adjustment, and regulatory network activity in response to P or N deficiency. <a href="javascript:void(0);">(56)</a> Ca is not always incorporated into protein structures. The Ca abundance determined from the proteins in this study, therefore, is much lower than the actual Ca needed intracellularly. Similarly, the intracellular Mg2+ and K+ abundances should also be higher than those determined from the protein structures. Free Mg2+ and K+ are known to regulate cation–anion balance and serve as osmotically active ions in the regulation of cells <a href="javascript:void(0);">(46)</a> but free metal ion concentrations cannot be determined through the approach used in this study. Thus, it is not surprising to see much higher relative abundances of Ca and Mg in ICP-MS analysis than in proteomic analysis (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acs.est.5c11233#fig3">Figure 3</a>).

Unlocking Phytoplankton Metallomes with Comparative Analysis of Metal Quotas, Quantitative Proteomics, and Inferred Metalloproteomes

<h3><a target="_blank" rel="noopener noreferrer" href="https://www.isc2026.org/">ISC 2026</a></h3>The <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/314">International Symposium on Chromatography (ISC)</a> represents the oldest conference series on separation science. ISC symposia have been organised since 1956 in each even year. ISC is one of the premier meetings series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.The major focus of the symposium will be on the impact of chromatography and separation science to meet the needs of the pharmaceutical, environmental, food and health industry, as well as science and medicine. The symposium programme will reflect these themes and highlight new challenges and emerging opportunities for the science and marketing of separation and detection systems and methods.As an integral part of the scientific programme of lectures and poster sessions, an international exhibition and vendor seminars on instrumentation and services for chromatography, separation science and mass spectrometry will be organised. ISC 2026 will provide the perfect forum for attendees from academia, industry and government research institutions for scientific exchange and networking.<h3>ISC 2026 SYMPOSIUM KEY DATES</h3><h4>6-10 SEPTEMBER 2026</h4><ul><li>15 January 2026: Opening of Early-bird Registration &amp; Abstract submission</li><li>11 March 2026: Deadline for abstract submission (orals)</li><li>21 April 2026: Sending acceptance letters (orals)</li><li>15 May 2026: Deadline of early-bird registration and payment &amp; Author registration deadline (orals)</li><li>1 June 2026: Preliminary detailed program on web</li><li>1 June 2026: Deadline for abstract submission (posters)</li><li>16 June 2026: Sending acceptance letters (posters)<ul><li>Authors who submit their abstracts with a poster preference by 5 May 2026 will be notified of the outcome by 12 May 2026 and will have the opportunity to register at the early-bird rate until 15 May 2026.</li></ul></li><li>30 June 2026: Author registration deadline (posters)</li><li>30 July 2026: Deadline for abstract submission (late-breaking posters)<ul><li>without the possibility of competing for the Best Poster Award</li></ul></li><li>11 August 2026: Sending acceptance letters (late-breaking posters)</li><li>18 August 2026: Author registration deadline (late-breaking posters)</li><li>25 August 2026: Deadline for late registration &amp; payment&nbsp;</li><li>6-10 September 2026: Symposium</li></ul><h3>REGISTRATION</h3><blockquote>👉<a target="_blank" rel="noopener noreferrer" href="https://www.czech-in.org/cmPortalV15/Account/Login?ReturnUrl=%2FcmPortalV15%2FPortal%2FISC26%2Fnormal">Register HERE for the ISC 2026</a></blockquote><h3>ABSTRACT SUBMISSION</h3><blockquote>👉<a target="_blank" rel="noopener noreferrer" href="https://www.czech-in.org/cmPortalV15/Account/Login?ReturnUrl=%2FcmPortalV15%2FPortal%2FISC26%2Fnormal">Submit your Abstract HERE</a></blockquote><h3>SCIENTIFIC PROGRAM</h3><h4>SHORT COURSES</h4><h5>SC 4 Hydrophilic Interaction Liquid Chromatography</h5>🗓️ SUNDAY, 6 SEPTEMBER 2026🕗 8:30 – 11:45Hydrophilic Interaction Chromatography (HILIC) has become an essential separation mode for the analysis of polar compounds that are poorly retained in reversed-phase LC. This chromatographic mode is more and more widely used in pharmaceutical analysis, biopharmaceutical characterization, and, above all, metabolomics, where enhanced retention, improved MS sensitivity, and complementary selectivity are indispensable. Despite its power, HILIC remains perceived as complex due to its mixed retention mechanisms, sensitivity to experimental conditions, and limited repeatability. A dedicated short course is therefore required to help users understand this technique in a robust and efficient way.This course will provide an in-depth and practical overview of HILIC fundamentals, starting with a discussion of the relatively complex retention mechanism. Particular emphasis will be placed on critical operational parameters such as sample diluent effects, which can drastically impact peak shape and retention, and on achieving good repeatability in gradient mode.Participants will also learn how coupling HILIC with MS can maximize sensitivity, and how to select both mobile phase components and stationary phases to obtain reliable and reproducible separations. Numerous applications will be covered, including typical small-molecule analyses, comprehensive metabolomic workflows, and the characterization of large biopolymers such as oligonucleotides, peptides, and proteins.In the end, this short course will help participants to confidently implement and troubleshoot HILIC in modern analytical laboratories.<h4>Lecturers</h4><h5><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/articles?search=Davy+Guillarme">Davy Guillarme</a></h5><ul><li>Davy Guillarme currently serves as an associate professor at the University of Geneva in Switzerland. With over 350 published journal his expertise spans various techniques, including UHPLC, HILIC, LC−MS, SFC, SFC-MS, multidimensional LC, and application to the characterization of biopharmaceuticals.</li><li>He is an editor of the Journal of Chromatography A and serves on the editorial advisory board of various other journals.</li><li>Davy Guillarme has been honored with the LC-GC Emerging Leader Award in Chromatography (2013), the Jubilee Medal from the Chromatographic Society (2018), the International Award of the Belgian Society of Pharmaceutical Sciences (2022) and the Csaba Horvath memorial award (2025).</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ISC_2026_Davy_Guillarme_c54bb7dd40.jpg" alt="ISC 2026: Davy Guillarme" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ISC_2026_Davy_Guillarme_c54bb7dd40.jpg 156w," sizes="100vw" width="500" height="500">

ISC 2026 Short Course 4 - Hydrophilic Interaction Liquid Chromatography

Article

Product

Events

Scientific article

Science and research

Video

A unique company dedicated to serving science helping our customers drive productivity and accelerate results. Through our premier brands – Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific and Unity Lab Services.

Thermo Fisher Scientific

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

LabRulez

The International Symposium on Chromatography (ISC) represents the oldest conference series focussing on separation science. ISC symposia have been organised since 1956 in each even year. ISC is internationally recognised as one of the premier meeting series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.

International Symposium on Chromatography - (ISC)

New Food magazine

Technology Networks

Bruker

Phenomenex

Shimadzu Corporation

Waters Corporation

<div><h4>Elevate Your DLS Knowledge</h4>Join us for the last 2 series on DLS and Dynamics! Optimize formulation development and understand particle concentration like never before.<h4>Session Overview:</h4><ul><li><h5>Part 4 of 5: High-Throughput DLS: Optimizing Formulation Development</h5><ul><li>Friday, November 7&nbsp;</li></ul></li><li>Part 5 of 5: Particle Concentration by DLS: Why Light Scattering Works, Even When ELISA is Wrong<ul><li>Friday, November 14</li></ul></li></ul><h4>Why Attend:</h4><ul><li>Deepen your understanding of DLS &amp; Dynamics.</li><li>Gain actionable insights for your lab.</li><li>Interact with our expert, Dr. Andy Meyer.</li></ul>The live interactive web series are 100% live sessions, with anonymous Q&amp;A welcome during and after the discussion. Free for all Wyatt customers.<blockquote>Hosted by: Dr. Andy MeyerDr. Andy Meyer joined Wyatt Technology in 2001, serving for several years as an Applications Scientist, then as Dean of Wyatt's "Light Scattering University" and as Director of Customer Service &amp; Support. After managing multiple regions in North America, Dr. Meyer is now a Senior Application Scientist for Wyatt. As a Wyatt customer, he completed his Ph.D. in Applied Science – Polymer Chemistry from the College of William and Mary in Virginia.</blockquote></div>

Waters Corporation: Becoming a DYNAMICS Expert

Becoming a DYNAMICS Expert: Part 4

Discover how high-throughput DLS accelerates formulation development. Join live and ask your questions anonymously with Dr. Andy Meyer on November 7.

Join Lorena Manzano as she demonstrates how advanced HRMS technology provides the sensitivity and confidence needed to monitor chemical contaminants, protecting both agricultural productivity and public health.This webinar will provide an overview of advanced high-resolution mass spectrometry (HRMS) strategies for monitoring pharmaceuticals and pesticides in complex environmental and agricultural matrices. Lorena Manzano will share recent findings on the occurrence, persistence and potential transfer of these contaminants from reclaimed water to soils and crops, highlighting how innovative analytical solutions can support safer water reuse practices.Water scarcity and the increasing use of reclaimed water for irrigation create both opportunities and challenges for agriculture. While reuse contributes to sustainability, it also introduces chemical contaminants into the food chain. Conventional monitoring approaches often fail to provide the sensitivity, selectivity and robustness required to detect low-level residues in highly complex samples such as soils and edible plant tissues.This webinar will address these challenges by discussing the role of HRMS, with a particular focus on how ZenoTOF technology enhances confidence in compound identification and quantification. Attendees will learn about key trends in environmental risk assessment, the importance of tracking persistent pharmaceuticals such as carbamazepine, and the role of multi-residue analysis in ensuring food safety.Case studies from real-world greenhouse experiments will be presented, demonstrating examples of pharmaceutical and pesticide transfer from wastewater to soils and edible crops. Finally, the session will provide actionable insights into how cutting-edge HRMS can be integrated into monitoring programmes to better protect both agricultural productivity and public health.<h5>You will learn:</h5><ul><li>Understand the occurrence and persistence of pharmaceuticals and pesticides in reclaimed water, irrigated soils, and edible crops.</li><li>Explore how HRMS ZenoTOF technology enhances detection, identification, and quantification of contaminants in complex matrices.</li><li>Learn from greenhouse case studies on pharmaceutical and pesticide accumulation under real-world irrigation practices.</li><li>Identify key challenges and opportunities for safe wastewater reuse in agriculture and food safety monitoring.</li></ul><blockquote>Presenter: Lorena Manzano Sánchez, PHD, University of AlmeríaLorena Manzano, PhD in Analytical Chemistry from the University of Almería, is an expert in advanced chromatographic and mass spectrometric techniques. With over six years of experience at the European Union Reference Laboratory for Fruits and Vegetables (EURL-FV), her work has focused on the application of LC- and GC-based high- and low-resolution mass spectrometry for the monitoring of pesticide residues in plant-derived matrices.</blockquote>

New Food Magazine: Protecting the food chain: Advanced HRMS strategies for contaminants in water and soil

Protecting the food chain: Advanced HRMS strategies for contaminants in water and soil

Webinar on advanced HRMS strategies for detecting pharmaceuticals and pesticides in water, soil, and crops to support safe reuse and protect public health.

Advanced HRMS for Contaminant Detection in Water & Soil

<div><h3>2nd Annual Oligos, Oligos, Oligos!</h3><h4>A special 3-part Live Webinar series focused on Oligonucleotide Analysis from Waters Corporation and Collaborators.</h4><h5>Seminar Series Summary</h5>Oligonucleotide therapeutics are helping the world address previously untreatable diseases, and their clinical pipeline continues to see strong growth. In various forms, including small interfering RNA (siRNA), Antisense Oligonucleotides (ASOs), CRISPR single guide RNA (sgRNA), and others, these nucleic acid modalities often incorporate a range of modified nucleotides for enhanced stability, and are increasingly conjugated to tissue-specific ligands (GalNAc, lipids, peptides, mAb’s, etc.) to effect targeted cell delivery. To advance their development, these molecules and their impurities must be fully characterized, and their stability and pharmacokinetic properties must be accurately assessed.In this webinar series, Waters’ scientists and collaborators from Novo Nordisk, Eli Lilly, and Synthon will provide state-of-the-art updates on the tools and techniques used to both confirm their identity and purity, and to quantify their pharmacokinetic properties in biological systems. &nbsp;Join us as we delve into the science of oligos and explore the power of LC and LC-MS based approaches to analyze them.<h4>EPISODE 2</h4><h5>sgRNA Single-Nucleotide Resolution by Ion-Pairing Reversed-Phase Chromatography</h5><ul><li>Speaker: Josh Jones /Eli Lilly</li></ul>In this episode, Eli Lilly will discuss the development of advanced analytical methods for single-stranded guide RNAs (sgRNAs), key therapeutic tools in CRISPR/Cas9 genome editing. Unlike shorter oligonucleotide therapeutics such as siRNAs and ASOs, sgRNAs pose unique challenges due to their longer sequences and complex folding. Lilly’s team systematically evaluated chromatographic parameters and discovered that more hydrophobic ion-pairing reagents, along with optimized flow rates and temperatures, significantly improved separation of long truncation impurities and resolution near the full-length product. The resulting method achieves single-nucleotide resolution while maintaining compatibility with mass spectrometry, offering unprecedented insights into sgRNA impurity profiles. This breakthrough will support toxicological studies and streamline process development for next-generation genetic medicines.<h5>Advanced LC-MS workflows for RNA Therapeutics to Ensure Product Quality and Process Consistency</h5><ul><li>Speaker: Hadi Maktabi / Waters Corporation</li></ul>As the therapeutic landscape increasingly incorporates longer RNA modalities, their longer sequence and structural complexity present significant analytical challenges. Robust strategies are therefore essential to ensure product quality and consistency. This presentation will demonstrate how high-resolution LC-MS workflows enable comprehensive monitoring of critical quality attributes (CQAs) and provide unambiguous sequence confirmation of these molecules. Case examples will highlight how advanced LC-MS methodologies deliver the resolution and specificity required for accurate characterization, supporting both process development and quality control of RNA-based therapeutics. &nbsp; &nbsp;&nbsp;<blockquote>Presenter: Josh Jones (Advisor – Analytical Chemistry, SMDD Eli Lilly)Josh Jones received his bachelor’s in Chemical Engineering from University of Illinois in 2018. He later received his Ph.D. in Chemistry from the University of Michigan under supervision of Kristin Koutmou and Robert Kennedy where he developed biochemical and analytical methods to characterize the endogenous post-transcriptional RNA modification landscape. In 2023, Josh started at Eli Lilly as an Advisor – Analytical chemistry, where he is developing analytical strategies and methodologies for Lilly’s genetic medicine portfolio.Presenter: Hadi Maktabi (Principal Biopharma Specialist, Waters Corporation)Hadi Maktabi, PhD, is the Biopharma Business Development Specialist at Waters, supporting customers across the U.S. West and Canada in advancing analytical solutions for therapeutic development. In this role, he partners with biopharma scientists to apply cutting-edge LC-MS and biophysical technologies to address complex drug development challenges.Prior to joining Waters, Hadi worked at ProteinSimple, where he supported biopharma researchers in applying capillary electrophoresis–based techniques (cIEF, CE-SDS, and SimpleWestern) for biotherapeutic characterization. He earned his PhD in Molecular Cell Biology from Washington University in St. Louis, where his dissertation research focused on protein palmitoylation dynamics and their role in membrane binding, trafficking, and spatial organization of signaling proteins, notably in regulating GPCR signaling.</blockquote></div>

Waters Corporation: 2nd Annual Oligos, Oligos, Oligos

Pushing the Limits of N-1 for Long RNA

Discover single-nucleotide sgRNA analysis and LC-MS strategies ensuring RNA therapeutic quality and consistency. Presented by Eli Lilly and Waters experts.

<div>The microbiome plays a crucial role in health, disease, and ecological balance, making its analysis essential for advancements in various fields such as medical research, food industry studies, and environmental science. In this regard, metaproteomics offers a powerful and efficient method to gain rapid insights into both the composition and activity of the microbiome by identifying, characterizing, and quantifying microbial proteins.This webinar will provide an overview of the sample preparation and mass spectrometry analysis stages involved in metaproteomics. Additionally, it will demonstrate the potential of this approach through a practical case study analyzing the effects of prebiotics on a fecal microbiome. Join us to explore how metaproteomics can enhance your research and provide deeper insights into microbial activity.<blockquote>Presenter: Morten Danielsen, Ph.D., Head of Metabolomics &amp; Proteomics Business Unit, Cmbio, Copenhagen, DenmarkMorten Danielsen, Ph.D., is the head of the Metabolomics and Proteomics Business unit at Cmbio. He has a scientific background as a microbiologist and has worked with analytical chemistry since 2010. He founded MS-Omics in 2014, together with Lea G. Johnson, which grew into a leading metabolomics provider in Europe. Later MS-Omics merged with Clinical-Microbiomics, CosmosID and DNASense to create a leading microbiome and multi-omics service provider/CRO named Cmbio. Cmbio has labs in Europe and the US, and a global team presence. Presenter: Adam Hughes, Key Account Manager, Northern Europe, PreOmics, Manchester, UKAdam joined PreOmics in 2024, with over 15 years of experience in the life sciences industry. PreOmics offers a comprehensive suite of sample preparation and proteomics solutions. Adam focuses on separation science, particularly sample preparation and chromatography, helping customers optimize their workflows and achieve reliable, reproducible results. Adam’s background includes a Master’s degree in Chemistry and more recently an MBA with the Open University, blending scientific expertise with commercial insight. Presenter: Pierre-Olivier Schmit, Proteomics Business Development Manager, Bruker Daltonics, Bordeaux, FrancePierre-Olivier Schmit joined Bruker in 2000 as an MS application and Demo scientist, after a double training in chemistry (Ecole Nationale Supérieure de Chimie de Montpellier) and biochemistry (university of Lund &amp; Montpellier) and a first experience in developing proteomics approaches (CNRS/Pierre Fabre).He took the head of the French demo lab, taking care of customer support, training and demo operations, and reinforcing an expertise in protein characterization and proteomics. He gradually shifted to a market management position from 2012 on, focusing on bottom-up and top-down proteomics approaches. Since 2021, he is acting as a proteomics business development manager for Western, Nordic and southern Europe.</blockquote></div>

Bruker: Metaproteomics as a tool to map prebiotic action

Metaproteomics as a tool to map prebiotic action

This webinar will provide an overview of the sample preparation and mass spectrometry analysis stages involved in metaproteomics. 

<div><div container-id="cq-colctrl-lt0" comp-id="A1"><div>PFAS contamination presents unique challenges, especially when it comes to detecting unknowns in complex samples. In this webinar, we’ll demonstrate how Thermo Scientific™ Compound Discoverer™ version 3.5 software introduces powerful new tools to streamline non-targeted PFAS analysis, enhance confidence in identification, and simplify data interpretation.<h5>By attending, you will learn how to:</h5><ul><li>Apply advanced Compound Discoverer 3.5 software features to improve non-targeted PFAS detection</li><li>Confidently identify and annotate unknown PFAS in challenging matrices</li><li>Streamline data processing and reporting for faster decision-making</li></ul><blockquote>Presenter: Richard Cochran, Ph.D. (Senior Application Scientist, LC-MS, Thermo Fisher Scientific)Richard Cochran is a Senior Application Scientist for LSMS at Thermo Fisher Scientific, with over 18 years of experience in mass spectrometry, with strong expertise in high-resolution mass spectrometry and untargeted analysis. Richard received his Ph.D. in Analytical Chemistry from the University of North Dakota. Prior to joining Thermo Fisher Scientific, Richard was a senior principal investigator within the Center for Aerosol Impacts on Chemistry of the Environment (CAICE, a National Science Foundation Center of Innovation) and served as the director of the Environmental and Complex Analysis Laboratory at the University of California, San Diego. Throughout his career he has published more than 20 scientific publications in the area of mass spectrometry, altogether having more than 1,500 citations. Currently Richard is a subject matter expert in the area of non-targeted PFAS analysis and helps scientists around the world, across many industries and scientific disciplines, improve the global environment and our quality of life.Moderator: Zoe Julian (Product Marketing Manager, Thermo Fisher Scientific)Zoe Julian is a product marketing manager for chromatography and mass spectrometry software at Thermo Fisher Scientific.With over 12 years' experience of working with chromatography and mass spectrometry techniques with a background in GC and GC-MS(/MS) organic environmental analysis, she has helped many laboratories and industries improve their workflows through a unique understanding of their challenges. Transitioning to a focus on software she has shown customers how software solutions can improve their productivity and support their day-to-day operations.</blockquote></div></div></div>

Thermo Fisher Scientific: From Complexity to Clarity: Smarter PFAS Identification Workflows

From Complexity to Clarity: Smarter PFAS Identification Workflows

The webinar will demonstrate how Thermo Scientific Compound Discoverer version 3.5 software introduces powerful tools to streamline non-targeted PFAS analysis

Smarter PFAS Identification Workflows

<div>Red blood cells (RBCs) offer a unique and minimally invasive window into neurodegeneration, yet their potential as a source of Parkinson’s disease biomarkers is only beginning to be explored.This webinar will showcase state-of-the-art mass spectrometry (MS) platforms that are able to identify protein signatures linked to earlier detection and improved disease monitoring. Our expert speaker will share new findings from RBC proteomics research, offering attendees a look at how this exciting area of proteomics and high-resolution MS may advance our understanding and clinical management of Parkinson’s disease.<h5>Attend this webinar to:&nbsp;</h5><ul><li>Understand the rationale for using RBCs in biomarker discovery for Parkinson’s disease</li><li>Learn how advanced MS workflows, such as data-independent acquisition and trapped ion mobility spectrometry – time-of-flight, enable deep proteome coverage</li><li>Review bioinformatics and statistical approaches for candidate biomarker identification and validation</li><li>Explore the translational potential of RBC proteomics for clinical applications</li></ul><blockquote>Presenter: Blaine Roberts, PhD (Associate Professor Department of Biochemistry, Emory University)Dr. Roberts is an Associate Professor in the Department of Biochemistry and Department of Neurology at Emory University. He obtained his Bachelor of Science in Chemistry at Montana State University and his PhD in Biochemistry and Biophysics from Oregon State University. His research group focuses on using protein biochemistry and mass spectrometry to understand Alzheimers, Parkinson’s and amyotrophic lateral sclerosis. He has interest in understanding the role of metals in biology and has developed new proteomic technologies to measure metalloproteins. Further, his group is using mass spectrometry and next generation quantitative assays for the development of new blood borne biomarkers for Alzheimers and Parkinson’s disease.</blockquote></div>

Bruker: Uncovering Parkinson’s Biomarkers Through Red Blood Cell Proteins

Uncovering Parkinson’s Biomarkers Through Red Blood Cell Proteins

Parkinson’s Biomarkers - Red Blood Cell Proteins

<div>Join us for a dynamic live demo that brings together experts from Immerse Delaware and Waters to show how cutting-edge bioprocessing analytics can enhance your understanding of cellular metabolism, transforming bioprocess development.You’ll see how Immerse Delaware uses at-line, automated LC-MS to monitor cell culture media and uncover metabolic shifts in real time, how Waters translates experimental data into actionable insights, and how statistical data analysis tools enable deeper statistical exploration to understand and optimize process parameters.This session is designed to help you gain a clearer understanding of cell cultures and use data-driven strategies to build more robust, scalable bioprocesses.<h4>Agenda:</h4><ul><li>An introduction to how walk-up, at-line analytical solutions are streamlining media analysis workflows and accelerating decision-making in bioprocess development</li><li>Learn from real-world experiments as Immerse Delaware shares how they’re using at-line analytics to monitor cell culture media and uncover metabolic trends</li><li>See how experimental data is translated into actionable insights using intuitive analytics platforms</li><li>Explore how JMP enables deeper statistical exploration and modelling to optimize bioprocess parameters and drive process robustness</li></ul>Reserve Your Spot Today!Whether you're in upstream development, process analytics, or data science, this session will demonstrate how integrated analytical workflows can empower your team to make faster, smarter decisions.<blockquote>Presenter: Caitlyn Da Costa Ph.D. (Principal Product Manager, Waters Biologics Business)Caitlyn Da Costa is Principal Product Manager for LCMS solutions in the bioprocess and PAT space at Waters. She oversees the development of in-line and on-line LCMS technologies for comprehensive in-process product quality and process monitoring. With a PhD in Mass Spectrometry and over a decade of experience in life sciences, Caitlyn pairs deep technical expertise with a passion for customer-driven design and collaborative innovation—delivering impactful solutions that address the dynamic needs of modern bioprocessing.Presenter: Patrick Boyce (Bioprocess Program Manager, Waters Corporation)Patrick Boyce is the Bioprocess Program Manager at Waters Corporation. He has worked in the field of analysis and separation sciences for over 35 years, the last 18 years of which have been at Waters. His work is focussed on analytics supporting upstream process development.Presenter: Richard Jeske (Senior Scientist, Waters Corporation)Richard Jeske is a Senior Scientist with over six years of experience in upstream bioprocessing and experimental design. He has applied Design of Experiments (DoE) to optimize diverse bioprocesses including monoclonal antibody production, cultivated meat, and stem cell-derived products. Richard is passionate about translating complex analytical data into actionable strategies that help accelerate process development.</blockquote></div>

Waters Corporation: Unlock Deeper Process Insights with Cutting-Edge Bioprocessing Analytics for Cell Culture Media Analysis

Unlock Deeper Process Insights with Cutting-Edge Bioprocessing Analytics for Cell Culture Media Analysis

How cutting-edge bioprocessing analytics can enhance your understanding of cellular metabolism, transforming bioprocess development.

Advanced Analytics for Cell Culture Media

In this webinar, we will present a solid phase extraction (SPE) method for quantifying GalNAc-conjugated siRNA in plasma and liver matrices, and will explore how optimizing key method parameters can significantly boost recovery rates and enhance analytical performance.<h4>Key Learning Points</h4><ul><li>Review key sample pre-treatment method strategies for the successful and improved recovery of GalNAC-conjugated siRNA in plasma and liver tissue.</li><li>Explore how find how Clarity OTX Pro SPE strategies differ when extracting ASOs versus GalNAc-conjugated siRNA oligonucleotides.</li><li>Learn how to choose the right Clarity OTX Pro well plate format for oligonucleotide extraction in complex matrices.</li></ul><h4>Who Should Attend</h4><ul><li>Anyone looking to begin or improve &nbsp;extraction of GalNAc-conjugated siRNA duplex oligonucleotides from plasma or liver samples using solid phase extraction (SPE).</li></ul><blockquote>Speaker: Mihir Thakar (Product Manager, Phenomenex)Mihir holds a master’s degree in Biotechnology. He has over a decade of experience working with various biopharma companies in the characterization of therapeutic peptides, proteins, and oligonucleotides. He has been associated with Phenomenex for more than 7 years, serving in various functions including as a Business Development Manager for Biologics. At present, he has been working as a Global Product Manager for the biopharma segment.&nbsp;Speaker: Roxana Eggleston-Rangel (Senior Applications Scientist, Phenomenex)Roxana joined Phenomenex in 2018 as an Applications Scientist and is currently working with the applications team to produce analytical solutions for the biopharma industry. Her current work focuses on characterization of mRNA, sgRNA and siRNA. Prior to Phenomenex, Roxana worked for Caltech and the University of Southern California developing LM-CS workflows for the proteomics community. She received her bachelor’s and master’s degree in Chemistry and Biochemistry from California State University, Los Angeles.</blockquote>

Phenomenex: New Clarity OTX Pro – Case Study: GalNAc siRNA Quantitation by SPE-LC-MS

New Clarity OTX Pro – Case Study: GalNAc siRNA Quantitation by SPE-LC-MS

In this webinar, we will present a solid phase extraction (SPE) method for quantifying GalNAc-conjugated siRNA in plasma and liver matrices

Clarity OTX Pro – GalNAc siRNA Quantitation by SPE-LC-MS

<div>Risk is no longer a static concept—it’s dynamic, data-driven, and deeply tied to how organizations manage information across systems, teams, and workflows. In regulated industries, the ability to analyze, mitigate, and monitor risk effectively is essential for ensuring patient safety, product quality, and operational continuity.In this session, we will explore how modern data governance practices can help organizations proactively identify risks, implement targeted mitigation strategies, and establish vigilant monitoring to support compliance and resilience.<h5>Attendees will gain practical insights into:</h5><ul><li>Conducting meaningful risk analysis across data and operational domains</li><li>Designing mitigation strategies that align with CGMP and QMM expectations</li><li>Building monitoring frameworks that detect issues before they escalate</li><li>Equipping teams with the tools and mindset to think critically and respond effectively in high-risk environments</li></ul>Whether you're upgrading and implementing new systems or refining your compliance strategy, this session will provide actionable guidance to help you strengthen your risk posture and elevate your data governance maturity.<blockquote>Presenter: Tracy Hibbs (Principal Consulting Product and Marketing Manager, Waters Corp.)Tracy has worked for Waters Corporation since 1999 and has held a variety of positions including Technical Trainer, Business Impact Consultant, Training Manager for Informatics and Data Integrity, and currently, Principal Consulting Marketing Manager focusing on Informatics solutions. Tracy provides support for Waters Empower Software Suite and is concentrated on developing laboratory data management software solutions that help organizations achieve their scientific and operational objectives in regulated environments. Prior to joining Waters, Tracy was a Research Scientist where she gained experience in chromatography and the associated data systems.​</blockquote></div>

Waters Corporation: Analysis, Mitigation, and Monitoring in Modern Data Governance

Analysis, Mitigation, and Monitoring in Modern Data Governance

Learn how data governance strengthens risk analysis, mitigation, monitoring to enhance compliance, safety, and operational resilience in regulated industries.

Analysis, Mitigation, and Monitoring in Data Governance

Evolving regulations in food safety and environmental monitoring demand faster, more accurate results—without increasing costs. In this Digital Classrooms session, discover how Shimadzu’s comprehensive suite of solutions for elemental analysis can help you meet these challenges head-on, no matter the complexity of your analysis requirements.Discover Shimadzu’s versatile solutions designed to meet diverse analytical challenges:<ul><li>ALTRACE EDXRF: Achieve rapid, non-destructive screening with minimal sample preparation and exceptional sensitivity reaching ppb levels.</li><li>ICPMS 2040/2050: Deliver precise quantification with the added advantage of reduced argon gas consumption and optimized operating costs.</li><li>LC-ICPMS: Go beyond total elemental content to identify and quantify chemical species of elements, hence enabling detailed evaluation of the benefits and/or risks associated with the elements present in a sample.</li></ul>Whether you're screening incoming raw materials, confirming regulatory compliance for food safety, monitoring environmental contaminants, or conducting speciation studies, this session will equip you with the right tools to optimize workflows, enhance data quality, and achieve superior results. Join us to discover practical applications, expert insights, and actionable strategies to stay ahead in a rapidly evolving landscape.<h4>Learning Objectives:</h4><ul><li>Gain insights into the latest regulations for elemental analysis</li><li>Explore Shimadzu’s innovative solutions for achieving accurate, high-throughput elemental analysis</li><li>Discover how ALTRACE simplifies and accelerates elemental analysis for greater efficiency.</li></ul><blockquote>Presenter: Goh Wan Yu Elton (Market Specialist For Food And Environmental, Shimadzu (Asia Pacific) Pte Ltd)Elton dedicates his career to food analytics, ensuring the safety and quality of our daily consumption. As a Food Specialist at Shimadzu, he develops and applies advanced analytical techniques to detect and quantify compounds in food products, from contaminants to nutrients. Elton takes pride in advancing food science, enhancing safety, and building consumer trust. His goal is to make valuable contributions to analytical chemistry and the global food industry.Presenter: Tan Teck Beng (Principal Product Specialist, Shimadzu (Asia Pacific) Pte Ltd)Tan Teck Beng is the Principal Product Specialist for Scientific Instruments at Shimadzu Asia Pacific. He holds a Master’s degree in Materials Science from the National University of Singapore and has over 24 years of experience in materials characterization and analytical techniques. His expertise spans XRF, EPMA, SPM, XPS, OES, and XRD. Mr. Tan has conducted numerous seminars and workshops across Asia, focusing on materials analysis, failure investigation, and RoHS compliance. He is recognized for his extensive technical support and training contributions to scientists and engineers in advanced material characterization.</blockquote>

Shimadzu: Elemental Analysis Made Easy: Innovative Solutions For Food & Environmental Testing

Elemental Analysis Made Easy: Innovative Solutions For Food & Environmental Testing

Discover Shimadzu’s ALTRACE, ICPMS, and LC-ICPMS solutions for efficient, precise elemental analysis in food safety and environmental monitoring.

Related content

ISC 2026 Short Course 4 - Hydrophilic Interaction Liquid Chromatography

Unlock High-Performance LC-MS with Factory-Certified Systems from Thermo Fisher Scientific

Unlocking Phytoplankton Metallomes with Comparative Analysis of Metal Quotas, Quantitative Proteomics, and Inferred Metalloproteomes