You may have the best HPLC system on the market, but to maximize your investment, you also need the best software to control the system and manage the data. If the software is complex to use, inflexible or lacking in functionality, it can greatly reduce your lab productivity, creating bottlenecks and inefficiencies. Furthermore, this can lead to unreliable results, increased error rates, cost implications and ultimately, a decrease in overall laboratory performance. By selecting the right Chromatography Data System (CDS) designed to meet current laboratory needs, you can eliminate errors and drive productivity with data that is accurate, trustworthy and secure.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Elevate_Your_HPLC_Performance_with_a_Modern_CDS_cc757246f7.jpg" alt="Thermo Fisher Scientific: Elevate Your HPLC Performance with a Modern CDS." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Elevate_Your_HPLC_Performance_with_a_Modern_CDS_cc757246f7.jpg 245w," sizes="100vw" width="1024" height="512"><h3>Be flexible and be in control</h3>So, what if you have multiple HPLC’s from different vendors? <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/76">Thermo Scientific Chromeleon CDS</a> offers full control over the widest range of HPLC and other chromatography instruments, including those from third-party manufacturers. This ensures you can maintain flexibility, while connecting and controlling your HPLC systems effortlessly. With features, such as auto-generated instrument panels that provide fast access to commands and live analysis plots, you can simplify navigation and enhance the overall user experience, making it easier to manage and monitor instruments.<h3>Streamline your method development and validation</h3>Support for your method development and validation needs is taken care of with predefined ICH method validation templates and built-in tools for method conversion, alongside integration with specialized software for automated and intelligent HPLC method development. This integration facilitates faster and more efficient method optimization and robustness testing, while the secure centralized data storage builds the perfect platform for compliance and future data review, providing a complete solution from method development to validation.<h3>Robust compliance and secure data management</h3><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/sp_70761_cds_ensure_compliance_sp70761_en_fd2abc669a.pdf">Compliance and security</a> can be a crucial aspect of any HPLC operation, and Chromeleon CDS effectively addresses these needs. Your instrument management starts with fast integrated wizard-driven instrument qualification covering IQ, OQ and PQ with predefined templates and reports to optimize the instrument qualification process. The software employs a privilege-based approach to control access to both the instruments and the system, ensuring that only authorized and qualified personnel can interact with them. Dedicated instrument audit trails track all actions and will provide you with a full history that is searchable ensuring traceability, safeguarding the integrity of your data and operations.<h3>Keep your instruments up and running</h3>Productivity is only maintained if your HPLCs are operational and available for use. Integrated diagnostic tests offer insight into key information such as lamp operating hours or piston seal wear with warning limits for timely replacements. The active monitoring of service and qualification status allows for convenient maintenance scheduling and prevents unnecessary instrument downtime. An overview of diagnostic outcomes can also be produced as part of a routine health check ensuring that your HPLC instruments are always in optimal condition.<h3>Get more right-first-time results</h3>How can you prevent delays, time-consuming investigations, and ensure your analytical sequence runs correctly the first time? Chromeleon CDS offers you solutions to minimize user interaction, such as ready checks that automatically verify instrument configuration, methods, and sequences for issues, and automated system equilibration, which ensures the first injection is always good, eliminating the need for blank injections at the start of a sequence saving time and solvent. Automated shutdown procedures will manage a completed run, ensuring safe shutdown, system flushing, or maintaining a low flow rate to prevent component damage. Built-in system suitability tests with the ability to make in-run decisions, such as pause, stop or continue will maintain the integrity of your data and allow you to perform actions like re-injections and auto-dilutions for when samples are outside acceptable tolerance limits. Streamlining and automating the entire process of sequence creation is achieved through <a target="_blank" rel="noopener noreferrer" href="https://documents.thermofisher.com/TFS-Assets/CMD/brochures/SP-70758-CDS-Chromeleon-Streamline-Workflow-SP70758-EN.pdf">eWorkflow procedures</a>. These pre-defined templates contain all associated methods and reports, so your HPLC sequence can be automatically generated with just a few clicks, reducing errors, minimizing training, and producing reliable results faster.<h3>A software designed to optimize HPLC lab efficiency</h3>Chromeleon CDS is a no-compromise solution for your HPLC systems, designed to provide you with faster and better results through enhanced control, flexibility, diagnostics, right-first-time results, and compliance. Its user-friendly interface, comprehensive method development and validation tools, secure data management, and advanced diagnostics make it an indispensable tool for your HPLC laboratory. Find out more by downloading the case study: <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/cs_003880_hplc_vanquish_sanofi_optimize_manufacturing_drugs_cs003880_na_en_cf986bf4cc.pdf">Leveraging a Vanquish UHPLC system and Chromeleon CDS to optimize the manufacturing process</a> or visiting <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/76">Chromatography Data System (CDS)</a>.Visit us on&nbsp;<a target="_blank" rel="noopener noreferrer" href="https://www.linkedin.com/showcase/72003132/admin/dashboard/">LinkedIn:</a>&nbsp;#Chromeleon #ChromatographyDataSystem #HPLC #UHPLC<section><blockquote><h5>Peter Zipfell</h5>For over 25 years, he has worked extensively with analytical hardware and software transitioning from LC-MS method development through HPLC technical support to chromatography data systems. His focus has always been to support our customers by delivering software solutions across multiple industries to enable them to improve their current workflows and increase productivity.</blockquote></section>

Elevate Your HPLC Performance with a Modern CDS

<h3><a target="_blank" rel="noopener noreferrer" href="https://www.isc2026.org/">ISC 2026</a></h3>The <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/314">International Symposium on Chromatography (ISC)</a> represents the oldest conference series on separation science. ISC symposia have been organised since 1956 in each even year. ISC is one of the premier meetings series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.The major focus of the symposium will be on the impact of chromatography and separation science to meet the needs of the pharmaceutical, environmental, food and health industry, as well as science and medicine. The symposium programme will reflect these themes and highlight new challenges and emerging opportunities for the science and marketing of separation and detection systems and methods.As an integral part of the scientific programme of lectures and poster sessions, an international exhibition and vendor seminars on instrumentation and services for chromatography, separation science and mass spectrometry will be organised. ISC 2026 will provide the perfect forum for attendees from academia, industry and government research institutions for scientific exchange and networking.<h3>ISC 2026 SYMPOSIUM KEY DATES</h3><h4>6-10 SEPTEMBER 2026</h4><ul><li>15 January 2026: Opening of Early-bird Registration &amp; Abstract submission</li><li>11 March 2026: Deadline for abstract submission (orals)</li><li>21 April 2026: Sending acceptance letters (orals)</li><li>15 May 2026: Deadline of early-bird registration and payment &amp; Author registration deadline (orals)</li><li>1 June 2026: Preliminary detailed program on web</li><li>1 June 2026: Deadline for abstract submission (posters)</li><li>16 June 2026: Sending acceptance letters (posters)<ul><li>Authors who submit their abstracts with a poster preference by 5 May 2026 will be notified of the outcome by 12 May 2026 and will have the opportunity to register at the early-bird rate until 15 May 2026.</li></ul></li><li>30 June 2026: Author registration deadline (posters)</li><li>30 July 2026: Deadline for abstract submission (late-breaking posters)<ul><li>without the possibility of competing for the Best Poster Award</li></ul></li><li>11 August 2026: Sending acceptance letters (late-breaking posters)</li><li>18 August 2026: Author registration deadline (late-breaking posters)</li><li>25 August 2026: Deadline for late registration &amp; payment&nbsp;</li><li>6-10 September 2026: Symposium</li></ul><h3>REGISTRATION</h3><blockquote>👉<a target="_blank" rel="noopener noreferrer" href="https://www.czech-in.org/cmPortalV15/Account/Login?ReturnUrl=%2FcmPortalV15%2FPortal%2FISC26%2Fnormal">Register HERE for the ISC 2026</a></blockquote><h3>ABSTRACT SUBMISSION</h3><blockquote>👉<a target="_blank" rel="noopener noreferrer" href="https://www.czech-in.org/cmPortalV15/Account/Login?ReturnUrl=%2FcmPortalV15%2FPortal%2FISC26%2Fnormal">Submit your Abstract HERE</a></blockquote><h3>SCIENTIFIC PROGRAM</h3><h4>SHORT COURSES</h4><h5>SC 3 Interpretation of Mass Spectra: Basic Introduction for Chromatographers</h5>🗓️ SUNDAY, 6 SEPTEMBER 2026🕗 8:30 – 11:45Mass spectrometry has become an essential tool in modern liquid chromatography, yet many chromatographers receive limited formal training in mass-spectral interpretation. This introductory short course provides a practical guide to understanding and interpreting mass spectra generated by the atmospheric-pressure ionization techniques coupled with LC: electrospray ionization (ESI), atmospheric-pressure chemical ionization (APCI), and atmospheric-pressure photoionization (APPI). The course begins by outlining the information that mass spectrometry adds beyond a chromatogram and clarifying which analytical questions mass spectrometry can – and cannot – answer. Participants receive a concise refresher on mass-spectrometric fundamentals, along with an introduction to key terminology. The principles and practical consequences of ionization methods are then discussed, with emphasis on how ionization physics, LC conditions, and mobile-phase additives shape spectral appearance. Building on this foundation, the course develops practical skills for interpreting LC-ESI spectra: locating the molecular ion, determining charge state, recognizing common adducts, distinguishing in-source artefacts, and using isotope patterns to support elemental-composition hypotheses. Participants then explore how MS/MS fragmentation provides structural clues, with straightforward rules of thumb for neutral losses and class-specific fragmentation behaviors. The course concludes with an integrative exercise that synthesizes chromatographic, full-scan, and MS/MS information to support spectral interpretation. By the end, participants will be equipped with the essential skills needed to interpret LC-MS spectra effectively and to apply mass-spectrometric reasoning in routine chromatographic analysis.&nbsp;<h4>Lecturers</h4><h5>Josef Cvačka</h5><ul><li>Josef Cvačka is head of the Mass Spectrometry Group at the Institute of <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/62">Organic Chemistry and Biochemistry of the Czech Academy of Sciences</a> and an associate professor at the Faculty of Science, Charles University in Prague. His research focuses on the structural analysis of bioactive organic compounds using advanced mass-spectrometric techniques. He develops methods for pinpointing double-bond and methyl-branching positions in lipids and aims to discover new lipid classes in biological samples. His laboratory also designs new ion sources for MS and HPLC/MS. He teaches and supervises students at Charles University and founded the <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/articles?search=Czech+Museum+of+Mass+Spectrometry">Czech Museum of Mass Spectrometry</a>.</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Josef_Cvacka_5cc8a0d1d4.jpg" alt="ISC 2026: Josef Cvačka" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Josef_Cvacka_5cc8a0d1d4.jpg 156w," sizes="100vw" width="510" height="510">

ISC 2026 Short Course 3 - Interpretation of Mass Spectra: Basic Introduction for Chromatographers

Eurachem and CITAC welcome analysts interested in the evaluation of chemical analysis uncertainty and in how to use this information in results interpretation. The Eurachem Week 2026 will begin with a training course on “Evaluation of the measurement uncertainty from in-house precision and recovery data” scheduled for Sunday, 10 May 2026. A two-days workshop on “Quality in Analytical Measurements: Uncertainty Evaluation and Results Interpretation” open to all interested participants will take place from 11 to 12 May 2026. On 13 May 2026, the Eurachem Working Groups will convene, followed by the Eurachem General Assembly, which will bring together the Executive and national delegates on 14 and 15 May. Both Working Group Meetings and the General Assembly are restricted to their members.The results of qualitative and quantitative chemical analyses should have an acceptable uncertainty, which should ideally be reported and considered in results interpretation.For many analytical applications, simplified uncertainty evaluations can determine uncertainty values that meet the defined requirements for this parameter. The workshop will focus on the key technical challenges involved in practical evaluations of measurement uncertainty based on precision and recovery data gathered during in-house method validation and quality control. There will be a discussion of how to model the variation of the measurement uncertainty within the analytical range and how to handle divergent recovery values from the analysis of various reference materials. A session on the use of measurement uncertainty in conformity assessment will explore how the risk of false conformity decisions can be managed.<blockquote><h5>New Eurachem guidance on using in-house precision and recovery data will be discussed at the workshop.</h5></blockquote>Topics will also include the validation and uncertainty evaluation for qualitative analyses with particular attention to current accreditation requirements for these types of analysis. The last session of the workshop will be dedicated to the evaluation of measurement uncertainty arising from sampling and using it to judge the fitness for purpose, and hence validation, of measurement procedures that include sampling. Four sessions of the workshop will include engaging breakout sessions where participants will have the chance to share their views about challenging aspects of the analytical work. Participants are invited to propose posters and oral communications on session topics or any other relevant topic for analytical chemists or stakeholders of the analytical work.<h3>Registration</h3><blockquote>👉<a target="_blank" rel="noopener noreferrer" href="https://conferences.chemistry.pt/register/eurachem2026">Register here for the workshop</a></blockquote><h4>Registration Fees</h4><h5>Early bird (EUR) - Until April 15th</h5><ul><li>Workshop: Regular participant (11 &amp; 12 May 2026): 400 EUR</li><li>Workshop: Student (11 &amp; 12 May 2026): 250 EUR</li><li>Eurachem Working Group1 (13 May 2026): 75</li><li>General Assembly2 (14 &amp; 15 May 2026): 250</li><li>Training On Uncertainty Evaluation3 (10 May 2026): 150</li></ul><h5>After April 15th</h5><ul><li>Workshop: Regular participant (11 &amp; 12 May 2026): 450 EUR</li><li>Workshop: Student (11 &amp; 12 May 2026): 300 EUR</li><li>Eurachem Working Group1 (13 May 2026): 100</li><li>General Assembly2 (14 &amp; 15 May 2026): 300</li><li>Training On Uncertainty Evaluation3 (10 May 2026): 200</li></ul><blockquote>§ - 50 EUR reduction for members of Eurachem, CITAC, SPQ, RELACRE, ForMEQ and SPMet at the workshop.10% reduction for organisations that registered more than one participant.1 - Working group members2 - Eurachem members3 - 50% reduction for workshop participants</blockquote><h3>Workshop</h3><h4>Eurachem/CITAC Workshop on Quality in Analytical Measurements:</h4><h5>Uncertainty Evaluation and Results Interpretation</h5>The results of qualitative and quantitative chemical analyses should have an acceptable uncertainty, which should ideally be reported and considered in results interpretation. For many analytical applications, simplified uncertainty evaluations can determine uncertainty values meeting defined requirements for this parameter. The workshop will focus on the key technical challenges involved in practical evaluations of measurement uncertainty based on precision and recovery data gathered during in-house method validation. It will be discussed how to model the variation of the measurement uncertainty within the analytical range and how to handle divergent recovery values from the analysis of various reference materials. A session on the use of measurement uncertainty in conformity assessment will explore how the risk of false conformity decisions can be managed.Topics will also include the validation and uncertainty evaluation of qualitative analyses with particular attention to current accreditation requirements for these types of analysis. The last session of the workshop will be dedicated to the evaluation of measurement uncertainty arising from sampling and using it to judge the fitness for purpose, and hence validation, of measurement procedures that include sampling.Four sessions of the workshop will include engaging breakout sessions where participants will have the chance to share their views about challenging aspects of the analytical work. Participants are invited to propose posters and oral communications on session topics or any other relevant topic for analytical chemists or stakeholders of the analytical work.<h3>Training Course</h3><h4>Evaluation of the measurement uncertainty from in-house precision and recovery data</h4><ul><li>10 May 2026</li></ul>A course on the fundamentals of the evaluation of the measurement uncertainty from in-house precision and recovery data will be held on Sunday, 10 May 2026. This training is targeted for analysts with a basic understanding of the measurement uncertainty concept, how uncertainty components propagate, and how the combined uncertainty is expanded. Following the morning presentation of the theory of uncertainty evaluation, the afternoon will be dedicated to applying the theory to real-world cases. Trainees should have basic skills in using Microsoft Excel spreadsheets and bring a laptop with Microsoft Excel to complete the exercises. The interaction between trainers and trainees will be promoted to guarantee learning efficiency.<h5>Trainers:</h5><ul><li>Ricardo Bettencourt da Silva, Faculdade de Ciências da Universidade de Lisboa, Portugal (rjsilva@ciencias.ulisboa.pt)</li><li>Stephen L. R. Ellison - UK National Measurement Laboratory (NML) hosted at LGC, United Kingdom</li><li>Vicki Barwick - UK National Measurement Laboratory (NML) hosted at LGC, United Kingdom</li></ul><h4>Agenda</h4><h5>8:00 Registration</h5><h5>9:00 Opening</h5><h5>9:05 Identifying, combining, and expanding uncertainty components: Theory and examples</h5><h5>9:45 Precision uncertainty: Theory and examples</h5><h5>10:30 Coffee break</h5><h5>10:50 Trueness-related uncertainty: Theory and examples</h5><h5>12:00 Additional questions and discussion</h5><h5>12:30 Lunch</h5><h5>13:30 Application example 1</h5><h5>15:30 Coffee break</h5><h5>15:50 Application example 2</h5><h5>17:00 Additional questions and discussion</h5><h5>17:30 Closing</h5><h3>Venue</h3>The series of Eurachem events will be held in:<ul><li>Meliã Lisboa Aeroporto ****</li><li>Rua C,2 1749-125 Lisboa, Portugal&nbsp;</li></ul>

Eurachem/CITAC Workshop on Quality in Analytical Measurements 2026

Software

Article

Product

Events

A unique company dedicated to serving science helping our customers drive productivity and accelerate results. Through our premier brands – Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific and Unity Lab Services.

Thermo Fisher Scientific

Eurachem is a European network promoting international traceability of chemical measurements and good analytical practice. It provides expert guidance, supports method validation, uncertainty evaluation, proficiency testing, and facilitates discussion on technical and policy issues in analytical quality.

Eurachem

The International Symposium on Chromatography (ISC) represents the oldest conference series focussing on separation science. ISC symposia have been organised since 1956 in each even year. ISC is internationally recognised as one of the premier meeting series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.

International Symposium on Chromatography - (ISC)

Metrohm

Agilent Technologies

Like many things, chromatography skills are built over time by reading, learning from colleagues, personal experiences, etc.
In this seminar, we’ll share with you some of the things we in tech support often send customers to help them build their chromatography knowledge.
Topics covered will include;
<ul>
<li>What to consider when scaling up or down in column size
</li>
<li>What to do when your column gets dirty
</li>
<li>Mobile phase considerations, including how you make it
</li>
<li>The role your instrument can play
</li>
</ul>
Whether you’re a seasoned chromatographer or new to LC, there’s always something to learn.
<blockquote>
Presenter: Rita Steed (Application Engineer, Agilent Technologies, Inc.)
</blockquote>
<blockquote>
Rita Steed began supporting the LC column line for Agilent in 1999. As a Chromatography Specialist (first with Chromatography, Inc., then directly for Agilent), Rita worked on-site with researchers in Pharmaceutical and other industries presenting technical seminars and assisting researchers with troubleshooting and method development. Rita has over 20 years of Chromatography experience in the Biotechnology, Chemical, and Pharmaceutical industries. She has held positions in Research, Sales, and Technical Service. Rita has earned degrees in Microbiology and Life Sciences/Biochemistry. In her current position, she is an inside Application Engineer supporting LC columns.
</blockquote>

Agilent Technologies: Things You May Not Know or May Have Forgotten

Things You May Not Know or May Have Forgotten

Build your HPLC chromatography knowledge.

In most HPLC separations there is a wanted interaction of the sample with a chromatography packing.
When doing GPC/SEC separations, that is not the case. GPC/SEC is a noninteractive technique that separates samples based on their size in solution and not on their chemistry. This presentation will cover the common questions that should be asked when developing a robust and reproducible GPC/SEC method.
Topics will include:
<ul>
<li>Sample type: protein vs polymer
</li>
<li>Solvent Selection and its importance
</li>
<li>Column Choices &amp; how to choose correctly
</li>
<li>Calibrants
</li>
<li>Detector &amp; Instrument Considerations
</li>
</ul>
As we discuss each topic area we’ll look at examples and provide valuable tips that can help you achieve long term reproducible and reliable results.
<blockquote>
Presenter: Jean Lane (Application Engineer, Agilent Technologies, Inc.)
</blockquote>
<blockquote>
Jean has been employed with Agilent since Nov 2010 in technical and applications support and has a primary role supporting Agilent’s full line of LC columns and consumables, which also includes support for Agilent’s GPC/SEC product line. She came to Agilent thru acquisition of Varian and the former Polymer Laboratories. Jean has 20 plus years of technical and applications support for both HPLC and GPC consumable products. In addition to practical chromatography experience in the laboratory, she has had many, many years in her technical role involving customer support providing assistance and troubleshooting for customer chromatography issues.
</blockquote>

Agilent Technologies: From Proteins to Polymers – GPC-SEC: Understanding Column Selection and Method Considerations for Your Sample

From Proteins to Polymers – GPC-SEC: Understanding Column Selection and Method Considerations for Your Sample

Common questions that should be asked when developing a robust and reproducible GPC/SEC method.

Understanding Column Selection and Method Considerations

When developing HPLC methods, isocratic and gradient methods offer different advantages. Knowing how to choose between the two types of methods is important for efficient method development.
In this talk we will look at how a scouting gradient can help determine whether an isocratic or gradient method is the best choice. The strengths of each will be discussed. They can help determine which to choose when conditions reasonably allow for a choice.
Lastly, we will briefly discuss how a scouting gradient can be used to optimize the conditions of an analytical gradient.
<blockquote>
Presenter: Paul Altiero (Application Engineer, Agilent Technologies, Inc.)
</blockquote>
<blockquote>
Paul Altiero is an Applications Engineer located at the Agilent Little Falls site in Wilmington, DE. Prior to coming to Agilent in 2009, Paul worked in the pharmaceutical industry performing LCMS bioanalysis supporting Drug Discovery DMPK. While at Agilent, Paul has been a field service engineer for LCMS as well as the integrating program manager for the RapidFire high throughput LCMS system. In his current role Paul’s responsibilities include technical support and application assistance for LCMS consumables.
</blockquote>

Agilent Technologies: Isocratic vs. Gradient: Making the Call

Isocratic vs. Gradient: Making the Call

How a scouting gradient can help determine whether an isocratic or gradient method is the best choice.

HPLC Isocratic vs. Gradient: Making the Call

With the addition of MS detection to HPLC analyses, certain considerations must be made in selecting columns and conditions.
In this seminar we will:
<ul>
<li>Discuss the fundamentals and applications of various LC/MS techniques.
</li>
<li>Look at column choices and mobile phase selection for LC separations as well as for MS sensitivity
</li>
<li>Address specific challenges to LC/MS analyses, such as interferences and ion suppression, will be addressed.
</li>
<li>The importance of sample preparation in minimizing problems with interferences will also be covered.
</li>
</ul>
<blockquote>
Presenter: Mark Powell (Application Engineer, Agilent Technologies, Inc.)
</blockquote>
<blockquote>
Mark Powell is an Applications Engineer located at Agilent’s Little Falls site in Wilmington, DE. Before joining Agilent in 2011, Mark worked in the pharmaceutical industry synthesizing, purifying and analyzing drug candidates. He provides applications assistance and technical support for Agilent’s HPLC columns and consumables.
</blockquote>

Agilent Technologies: Making LC Methods MS Friendly

Making LC Methods MS Friendly

With the addition of MS detection to HPLC analyses, certain considerations must be made in selecting columns and conditions.

How the chromatographic process works is not magic.
It is described by a few key parameters, such as resolution, retention factor, and selectivity. Understanding the equations that define these parameters can make them less intimidating.
In this talk we will discuss:
<ul>
<li>What they are and where they come from
</li>
<li>Their importance
</li>
<li>The effect they have on our chromatography
</li>
<li>When they don’t matter
</li>
</ul>
A better grasp of this key information helps make the separation work for us.
<blockquote>
Presenter: Bill Champion (Application Engineer, Agilent Technologies, Inc.)
</blockquote>

Agilent Technologies: Demystifying the Chromatographic Process

Demystifying the Chromatographic Process

How the chromatographic process works is not magic.

Developing reversed-phase chromatographic methods can often be both more efficient and made better by use of a systematic approach rather than a “random walk”.
Combining simple experimental design with chromatographic understanding can help us better understand how the chromatographic parameters affect the separation.
In this talk, we will discuss the use of simple experimental design to optimize our method development and how it can:
<ul>
<li>Help make the method more robust</li>
<li>Help us understand and predict chromatographic behavior</li>
<li>Make it possible to know which parameters are really important</li>
</ul>
Most of these experiments can be set up to run in a simple overnight sequence.
<blockquote>
Presenter: Bill Champion (Application Engineer, Agilent Technologies, Inc.)
</blockquote>

Agilent Technologies: Systematic Approach vs. Random Walk - Improving the Efficiency of Method Development and Optimization

Systematic Approach vs. Random Walk - Improving the Efficiency of Method Development and Optimization

Use of simple experimental design to optimize our method development.

HPLC Method Development and Optimization Basics

Whether you develop HPLC methods, run QC samples or perform contract analyses, longer analysis times cost more and FAST LC columns can help you reduce those costs.
In this seminar we will look at:
<ul>
<li>Easy-to-follow steps for converting existing methods
</li>
<li>Developing new, faster methods on existing equipment
</li>
<li>System improvements and adjustments, like flow path connections and detector acquisition rates that can help you get the best performance with your existing system.
</li>
</ul>
We’ll also discuss when and why to consider an enhanced UHPLC systems.
<blockquote>
Presenter: Rita Steed (Application Engineer, Agilent Technologies, Inc.)
</blockquote>
<blockquote>
Rita Steed began supporting the LC column line for Agilent in 1999. As a Chromatography Specialist (first with Chromatography, Inc., then directly for Agilent), Rita worked on-site with researchers in Pharmaceutical and other industries presenting technical seminars and assisting researchers with troubleshooting and method development. Rita has over 20 years of Chromatography experience in the Biotechnology, Chemical, and Pharmaceutical industries. She has held positions in Research, Sales, and Technical Service. Rita has earned degrees in Microbiology and Life Sciences/Biochemistry. In her current position, she is an inside Application Engineer supporting LC columns.
</blockquote>

Agilent Technologies: High Resolution Fast LC - Easier Than You Think with Simple Changes

High Resolution Fast LC - Easier Than You Think with Simple Changes

Developing new, faster methods on existing HPLC equipment.

Easier Than You Think with Simple Changes

Operating an HPLC can be overwhelming to a new user.
There are many pitfalls or “gotchas”. Even the issue of what tubing and fittings are compatible and which are not can be a serious impediment to successfully operating the HPLC.
In this talk, we will discuss:
<ul>
<li>The importance of connections
</li>
<li>Mobile Phase considerations
<ul>
<li>Quality
</li>
<li>Preventing microbial growth
</li>
<li>Sample/solvent compatibility
</li>
</ul>
</li>
<li>Column Characteristics; Their importance and limitations
</li>
<li>The importance of sample prep
</li>
</ul>
Avoiding these pitfalls can help you achieve long-term, reliable results.
<blockquote>
Presenter: Rita Steed (Application Engineer, Agilent Technologies, Inc.)
</blockquote>
<blockquote>
Rita Steed began supporting the LC column line for Agilent in 1999. As a Chromatography Specialist (first with Chromatography, Inc., then directly for Agilent), Rita worked on-site with researchers in Pharmaceutical and other industries presenting technical seminars and assisting researchers with troubleshooting and method development. Rita has over 20 years of Chromatography experience in the Biotechnology, Chemical, and Pharmaceutical industries. She has held positions in Research, Sales, and Technical Service. Rita has earned degrees in Microbiology and Life Sciences/Biochemistry. In her current position, she is an inside Application Engineer supporting LC columns.
</blockquote>

Agilent Technologies: New to HPLC? Tips for Avoiding Beginner Pitfalls

New to HPLC? Tips for Avoiding Beginner Pitfalls

What tubing and fittings are compatible and which are not can be a serious impediment to successfully operating the HPLC.

GPC/SEC, Gel Permeation Chromatography or Size Exclusion Chromatography, is a non-interactive chromatographic technique that separates analytes based on their size in solution.
It is often used in laboratories for determination of a polymers&#39; molecular weight distribution but has many other uses.
In this talk we will:
<ul>
<li>Review GPC theory
</li>
<li>Discuss why molecular weight distribution is important
</li>
<li>Look at the different types of columns and their uses
</li>
<li>Cover key column selection criteria
</li>
<li>Show how key parameters like concentration, particle size, and injection volume can affect your separation
</li>
</ul>
We will also look at examples of common mistakes and pitfalls relating to solvent choice, calibration standards, and combining columns in series.
<blockquote>
Presenter: Jean Lane (Application Engineer, Agilent Technologies, Inc.)
</blockquote>
<blockquote>
Jean has been employed with Agilent since Nov 2010 in technical and applications support and has a primary role supporting Agilent’s full line of LC columns and consumables, which also includes support for Agilent’s GPC/SEC product line. She came to Agilent thru acquisition of Varian and the former Polymer Laboratories. Jean has 20 plus years of technical and applications support for both HPLC and GPC consumable products. In addition to practical chromatography experience in the laboratory, she has had many, many years in her technical role involving customer support providing assistance and troubleshooting for customer chromatography issues.
</blockquote>

Agilent Technologies: Gel Permeation Chromatography Basics and Beyond

Gel Permeation Chromatography Basics and Beyond

GPC/SEC, Gel Permeation Chromatography or Size Exclusion Chromatography.

Karl Fischer (KF) titration is an industry standard method for measuring water content in all types of substances.
However, for various reasons some substances are not suitable for a direct Karl Fischer titration:
<ul>
<li>They release their water only slowly
</li>
<li>The water is released at high temperature only
</li>
<li>The substances are poorly soluble in KF solvents
</li>
<li>They undergo side reactions with KF reagents
</li>
<li>They contaminate the titration cell or the electrodes
</li>
</ul>
By using the KF oven technique, the above-mentioned problems can be avoided. This makes the KF oven technique a perfect solution for the analysis of difficult samples.
By viewing this webinar you will learn…
<ul>
<li>how to analyse difficult samples
</li>
<li>how to properly prepare your titration system with KF oven
</li>
<li>how to prepare your sample
</li>
<li>how to select the optimal heating temperature
</li>
<li>which reagents and which water standards you should use to obtain accurate results
</li>
</ul>
After viewing this webinar you will know how to perform accurate titrations using the Karl Fischer oven technique. Additionally, the speakers will reveal tips and tricks to help you in the daily routine. The webinar will finish with live Q&amp;A session.
<blockquote>
Presenter: Michael Margreth (Senior Product Specialist Titration, Metrohm International Headquarters, Switzerland)
</blockquote>
<blockquote>
Michael Margreth studied chemistry at the University of Applied Science in Muttenz, Switzerland. He joined Metrohm in 2005 as an application specialist and gained titration experience in the application laboratory. Since 2008 he mainly focuses on Karl Fischer titration and the determination of water.
</blockquote>
<blockquote>
Presenter: Agnieszka Kossakowska (HYDRANAL Marketing Specialist, Honeywell Research Chemicals)
</blockquote>
<blockquote>
Agnieszka Kossakowska joined Honeywell in March 2016 as a marketing specialist providing technical support and onsite seminars for Honeywell’s Hydranal™ reagents for Karl Fischer titration. Agnieszka has more than 10 years of experience in analytical chemistry and conducts training across Europe, Middle East &amp; Africa, Latin America and Asia.
</blockquote>

Metrohm: Tips and tricks to analyze difficult samples using the Karl Fischer oven technique

LCMS webinars focusing on Academy/Principles - page 39