<div><div><div><div><h3>How Does Your Monthly Nitrogen Gas Bill Compared to Other Labs?</h3>If your lab relies on nitrogen gas cylinders, you already know how quickly costs can add up. Between purchase prices, rental fees, delivery charges, and frequent refills, <a target="_blank" rel="noopener noreferrer" href="https://blog.organomation.com/blog/understanding-the-costs-of-renting-nitrogen-gas-cylinders-in-laboratories?hsLang=en">nitrogen cylinders can become a hidden financial drain</a> on your operations.But how do you know if you're paying a fair price—or if you're overspending compared to other labs? Our "Am I Overpaying on my Nitrogen Gas Cylinders?" tool helps you determine whether your current nitrogen supply costs are within an acceptable range or if you're paying too much.<h3>The Hidden Costs of Nitrogen Cylinders</h3>Nitrogen cylinders are a staple in many laboratories, but they come with several costly drawbacks:<h4>1. High Cylinder Costs</h4>The upfront cost of nitrogen cylinders can be significant, especially for labs that require multiple cylinders per month. Pricing varies depending on size and supplier, but the recurring need to purchase or replace cylinders creates an ongoing expense that can quickly add up. Unlike a fixed investment in a nitrogen generator, cylinder costs are a constant and unavoidable part of lab operations.<h4>2. Monthly Rental Fees</h4>Most gas suppliers charge a rental fee per cylinder, adding to the overall cost of maintaining a steady nitrogen supply. These fees might seem small at first, but when multiplied across multiple cylinders and months, they become a substantial recurring expense. Over time, these rental costs can easily surpass the price of investing in an in-house nitrogen generation system.<h4>3. Delivery &amp; Handling Expenses</h4>Delivery costs vary but can add hundreds of dollars per month to your nitrogen expenses, especially if you're receiving frequent shipments. Beyond costs, frequent deliveries create workflow disruptions and safety concerns due to cylinder handling and storage. Each delivery requires time, coordination, and often additional fees, making cylinders an inefficient option for labs that require a reliable nitrogen supply.<h4>4. Gas Waste</h4>Did you know that most nitrogen cylinders leave about 10% of their gas unused due to pressure limitations? That means you're paying for nitrogen you can’t even use. Additionally, each time a cylinder runs empty, there is downtime involved in switching to a new one, causing further inefficiencies in lab operations.<h4>5. Storage &amp; Safety Risks</h4>Cylinders require dedicated storage space and proper handling to prevent leaks, pressure hazards, and accidents. Many labs struggle with cylinder management, leading to compliance concerns and workflow inefficiencies. Storing multiple high-pressure cylinders also introduces potential safety risks, requiring strict adherence to safety protocols and regulatory standards.<h3>The Smarter Alternative: Switching to a Nitrogen Generator</h3>A nitrogen generator offers a cost-effective, on-demand solution for labs that need a steady nitrogen supply—without the ongoing expenses of cylinder rentals, refills, and deliveries. Here’s why more labs are making the switch:<ul><li>Eliminate Cylinder Costs – No more purchases, rentals, or refills.</li><li>Reduce Long-Term Expenses – A one-time investment with minimal maintenance.</li><li>On-Demand Supply – Generate high-purity nitrogen whenever you need it.</li><li>No More Deliveries – Say goodbye to disruptions and recurring delivery fees.</li><li>Increased Safety &amp; Efficiency – No handling of high-pressure cylinders.</li><li>Better Environmental Impact – <a target="_blank" rel="noopener noreferrer" href="https://blog.organomation.com/blog/are-nitrogen-generators-actually-more-environmentally-friendly?hsLang=en">Reduce carbon emissions</a> associated with cylinder deliveries and production.</li></ul>Many labs find that a <a target="_blank" rel="noopener noreferrer" href="https://www.organomation.com/would-a-nitrogen-generator-make-sample-preparation-more-affordable?hsLang=en">nitrogen generator pays for itself within a year</a>—especially if they use multiple cylinders per month. Beyond the financial savings, labs that <a target="_blank" rel="noopener noreferrer" href="https://blog.organomation.com/blog/why-nitrogen-generators-are-gaining-popularity?hsLang=en">switch to a nitrogen generator</a> experience greater efficiency, safety, and reliability in their daily operations.<blockquote>Learn More: <a target="_blank" rel="noopener noreferrer" href="https://www.organomation.com/nitrogen-generators-for-sample-preparation-everything-you-need-to-know?hsLang=en">Nitrogen Generators for Sample Preparation: Everything you need to know</a>Watch Our Webinar: <a target="_blank" rel="noopener noreferrer" href="https://explore.organomation.com/the-case-for-nitrogen-generation-in-your-lab?hsLang=en">Improving Laboratory Workflows with Nitrogen Generation</a></blockquote><h3>Find Out If You’re Overpaying</h3>Not sure if switching to a nitrogen generator makes sense for your lab? Use our "Am I Overpaying on My Nitrogen Gas Cylinders?" tool to compare your costs against industry benchmarks. Simply answer a few quick questions, and we’ll help you determine whether it’s time to make the switch.</div></div></div></div>

Am I Paying Too Much for my Nitrogen Gas Cylinders?

Intensive farming, even when good agricultural practices are followed, very often results in pesticide contamination of soil, surface water and groundwater. Water sources used for drinking water production are thus often affected. The outcome is the progressive banning of proven, effective, yet persistent pesticides in the environment, alongside a decline in water quality. This, in turn, results in substantial investments in water treatment technologies to ensure that drinking water meets relevant legal standards. Passive, easy to maintain and low-cost in-situ denitrification woodchip bioreactors might be a solution to this situation. These bioreactors have already been successfully used in some countries (e.g. the USA) to remove other types of agricultural pollution directly at the point of origin, thus preventing its further transport in the environment.&nbsp;<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ALS_Czech_Republic_Enviro_Mail_17_Europe_Protecting_Drinking_Water_Sources_with_Bioreactors_An_Innovative_Solution_to_the_Problem_of_Pesticides_in_the_Landscape_ba53628b5a.jpg" alt="ALS Czech Republic: EnviroMail™ 17/Europe: Protecting Drinking Water Sources with Bioreactors: An Innovative Solution to the Problem of Pesticides in the Landscape: Figure 1: A real example of an installed semi-operational bioreactor unit." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ALS_Czech_Republic_Enviro_Mail_17_Europe_Protecting_Drinking_Water_Sources_with_Bioreactors_An_Innovative_Solution_to_the_Problem_of_Pesticides_in_the_Landscape_ba53628b5a.jpg 245w," sizes="100vw" width="1971" height="919"><h3>Nitrates and Denitrifying Bioreactors</h3>Denitrifying woodchip bioreactors are a relatively simple containerised treatment technology originally intended for the removal of nitrates from agricultural outflows. They use woodchip media as a source of bioavailable organic carbon to promote denitrification, which converts nitrates to gaseous nitrogen, the predominant natural component of the atmosphere. The advantages of using denitrification woodchip bioreactors are low acquisition and operating costs, minimal maintenance, long lifetime, and low land take. At some sites, these bioreactors have been operated for more than 15 years without major interventions and with the original fill and still achieve high denitrification rates.<h3>ALS Research Project</h3>To verify the usability of denitrifying woodchip bioreactors for the simultaneous removal of both nitrates and pesticides found in surface runoff from agriculturally active areas is the goal of research project "Comprehensive assessment of soil contamination with pesticides and in-situ remediation leading to eliminate their entry into groundwater“. The project is being realised under the leadership of ALS Laboratories in cooperation with other research institutes. Work on the project will continue until 2025.<h3>Semi-operational Unit and Expected Pesticides Removal</h3>Previous research projects by ALS and their partners have thoroughly mapped and identified sites that have been, in terms of pesticides occurrence, problematic for a long time. A semi-operational unit of the denitrification woodchip bioreactor described above was commissioned at one of these sites in the autumn of 2023.The unit uses poplar wood chips as a feedstock, which have proven well for this purpose, and is equipped with automatic samplers, sensors measuring basic physical and chemical parameters and a data station with on-line data transmission.In the case of pesticides, several decontamination mechanisms are envisaged in the bioreactor area, the most important of which will be the sorption and microbial decomposition. The aim of the project is to suggest the operating conditions of the bioreactor in such a way that the natural processes of microbial degradation of pesticides are facilitated to the maximum extent possible, or to support these processes by active intervention in the physicochemical composition of the bioreactor and its microflora.<blockquote>Related EnviroMail_08_Europe: <a target="_blank" rel="noopener noreferrer" href="https://www.alsglobal.eu/enviromails/enviromail_08">Hidden Pesticide Threats in Protected Landscape Areas</a></blockquote><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ALS_Czech_Republic_Enviro_Mail_17_Europe_Protecting_Drinking_Water_Sources_with_Bioreactors_An_Innovative_Solution_to_the_Problem_of_Pesticides_in_the_Landscape_2_4e7e587035.jpg" alt="ALS Czech Republic: EnviroMail™ 17/Europe: Protecting Drinking Water Sources with Bioreactors: An Innovative Solution to the Problem of Pesticides in the Landscape: Figure 2: Results of pesticides detected in tested soil samples." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ALS_Czech_Republic_Enviro_Mail_17_Europe_Protecting_Drinking_Water_Sources_with_Bioreactors_An_Innovative_Solution_to_the_Problem_of_Pesticides_in_the_Landscape_2_4e7e587035.jpg 245w," sizes="100vw" width="1439" height="783"><h3>Case Study: Monitoring of Pesticides in Soil Sam- ples from Central Europe</h3>In June 2023, monitoring of pesticides in agricultural soils and surrounding surface waters was conducted from 45 sites across Central Europe. The range of determined targeted substances was based on prepared risk analysis taking into account the consumption of pesticides and their risk properties such as toxicity and persistence. Analytical methods based on liquid chromatography coupled to tandem mass spectrometry (UPLC-MS/MS) were used to determine a wide range of active pesticide substances and their metabolites (308 and 352 parameters, respectively). Results are summarized in Figure 2.Pesticides were detected in all collected soil samples ranging from 0.01 to 0.73 mg/kg DW (dry weight of soil). By far the most abundant group was glyphosate pesticides, i.e. the herbicide glyphosate and especially its metabolite AMPA (Aminomethylphosponic acid), its total concentrations ranged from 0.01 to 0.46 mg/ kg DW in 36 of the 45 samples collected and tested. Comparing to levels and incidence of pesticides within the Europe, glyphosate and AMPA belong to the most frequently detected and those with the highest concentrations pesticide compounds generally.In related surface water samples, pesticides were detected in 43 out of 45 tested samples, their concentrations ranged from 0.01 μg/L to 14.1 μg/L. The most abundant pesticides detected were chloracetanilide and glyphosate.<h3>Protective Measures in the Landscape</h3>Based on the results obtained during the testing of the semi-operational denitrification woodchip bioreactor unit, a linear measure will be designed and properly sized for the model catchment to remove pesticides directly at the point of generation and thus prevent their further spread.<h3>European Legislation</h3><ul><li>SOIL: Proposal COM(2023) 416 final of 5 July 2023 for a directive of the European Parliament and of the Council on Soil Monitoring and Resilience (Soil Monitoring Law).</li><li>SURFACE WATER: Directive 2008/105/EC of the European Parliament and of the Council of 16 December 2008 on environmental quality standards in the field of water policy, amending and subsequently repealing Council Directives 82/176/EEC, 83/513/EEC, 84/156/EEC, 84/491/EEC, 86/280/EEC and amending Directive 2000/60/EC of the European Parliament and of the Council.</li><li>GROUND WATER: Directive 2006/118/EC of the European Parliament and of the Council of 12 December 2006 on the protection of groundwater against pollution and deterioration.</li><li>DRINKING WATER: Directive (EU) 2020/2184 of the European Parliament and of the Council of 16 December 2020 on the quality of water intended for human consumption (recast).</li></ul>

EnviroMail™ 17/Europe: Protecting Drinking Water Sources with Bioreactors: An Innovative Solution to the Problem of Pesticides in the Landscape

Mushrooms – a fragrant forest treasure for some, a fascinating object of study for others. In this case, the connection between nature and science is entirely natural. What can you discover about a simple mushroom under a microscope or using chromatography? And how helpful is a scientific education when it comes to everyday mushroom hunting?&nbsp;We asked RNDr. Roman Kysilka, CSc., who worked as a research specialist at the Czechoslovak Academy of Sciences and now works at <a target="_blank" rel="noopener noreferrer" href="https://watrex.com/?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_clanky">Watrex Prague</a>. He walked us through not only his career, but also through the forest – both scientific and real.&nbsp;<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Watrex_19_6_uvod_1600_X900_4dca2a04b3.jpg" alt="Watrex Fig.1: RNDr. Roman Kysilka, CSc." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Watrex_19_6_uvod_1600_X900_4dca2a04b3.jpg 245w," sizes="100vw" width="3540" height="1875"><h4>When and why did you decide to study natural sciences? Were you drawn to them as a child?</h4>I got a chemistry experiment kit, I think it was called "Curious Chemist," around seventh grade, and I was immediately captivated by home experiments. I was also into electricity and experimented with that as well. In my early years of high school, I was still considering studying electrical engineering or chemistry. But chemistry won out, largely thanks to the chemistry olympiads I took part in regularly from elementary school. Through national competitions (later in high school), I met a lot of chemistry enthusiasts. And during training camps for the international olympiad, I got to know chemists from the Faculty of Science at Charles University – and that sealed the deal.<h4>How did you first get into studying mushrooms? Was it by chance or intentional?</h4>It was a coincidence. I did grow champignons when I was around twelve, but that had nothing to do with research – I was mostly curious about what my mom would cook with them. Between 1982 and 1984, I was working on my thesis, and my advisor, Prof. Karel Štulík, arranged for me to work in a chromatography lab in the Department of Experimental Mycology at the Institute of Microbiology of the Czechoslovak Academy of Sciences. And that’s where I first encountered mushrooms as a subject of scientific research.&nbsp;<h4>What fascinated you most about mushrooms?&nbsp;</h4>Mushrooms have been with humankind since ancient times. You might recall the phrase “mushrooms – meat of the poor.” The Aztecs used the word teonanácatl, which roughly translates as “meat of the gods” (later found to refer to mushrooms with psychoactive effects). Meat for both the poor and the gods – interesting, right? The diverse world of fungi – heterotrophic organisms with a vital role in nature – fascinated me from the start. And of course, there’s also the unexpected potential of the compounds mushrooms produce. Every year, hundreds of new, previously unknown chemical compounds – secondary metabolites – are isolated and described in scientific literature, with potential uses in medicine and other fields. You could say the world of fungi is still largely unexplored from a chemical standpoint.&nbsp;<h4>You worked at the Czechoslovak Academy of Sciences from 1985–1991 – what exactly did you do there?&nbsp;</h4>After returning from military service, I went back to the Institute of Microbiology, where I focused on research into psychoactive tryptamine derivatives in basidiomycetes for my dissertation. The list of substances later narrowed to psilocybin, psilocin, baeocystin, and bufotenin. I worked on developing analytical methods to detect these compounds in fruiting bodies and mycelium, designing chromatographic methods for semi-preparative scale isolation, conducting cultivation experiments with various Psilocybe species in the lab, and screening potentially psychoactive mushrooms for these compounds.&nbsp;<h4>Do you recall a moment or discovery that left a strong impression on you?&nbsp;</h4>Yes. Part of the research on magic mushrooms included experimental poisonings. In the late 1980s, together with Marta Semerdžieva, we completed (and later patented) a method for producing mushroom mycelium via submerged cultivation. We planned an intoxication experiment using this rather unappealing material. Based on HPLC analysis, we cooked a “mushroom” soup and began the experiment. However, the outcome was very different from what we expected – it was clear we had significantly overdosed the test subjects. That prompted a detailed review of the analytical method used to determine psilocybin and psilocin levels. We found that the critical step for accurate results was the sample preparation before HPLC analysis. With optimized extraction, we detected concentrations of active compounds several times higher than with previously published methods. Our article in Planta Medica is still cited today and occasionally discussed in forums about psychoactive substances.&nbsp;<h4>What techniques were you using then – and what surprises you most about modern lab methods?&nbsp;</h4>Our main analytical technique was HPLC. Mass spectrometry, which is standard today, was just a dream back then. The peak was using a UV-VIS diode-array detector or selective and sensitive amperometric detection. I find the current development of lab automation, the explosive growth of computing and mathematical modeling, and more recently, the use of artificial intelligence truly remarkable.<h4>How did you transition from academia to Watrex Prague? What attracted you to the change?</h4>In the early '90s, research projects at the Institute of Microbiology were being reorganized, and several colleagues I worked with left the institute. Around the same time, I got a job offer from Milan Minárik, who was founding <a target="_blank" rel="noopener noreferrer" href="https://watrex.com/?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_clanky">Watrex</a> – a distributor for <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/325">Waters</a> chromatography systems. I had met Milan a few years earlier (through HPLC, of course), and the idea of working as an applications specialist in his private company was very appealing. It was a time of rapid private sector growth in Czechoslovakia, and I was excited to be a part of that.&nbsp;<h4>You’ve studied mushrooms scientifically, but what about in the actual forest? Are you a mushroom picker?</h4>I love picking mushrooms (their fruiting bodies), but I don’t have as much time for it as I’d like.&nbsp;<h4>How much do you rely on your scientific knowledge when mushroom picking? Do you see mushrooms differently than the average picker?&nbsp;</h4>Rather than scientific knowledge, I rely on experience from field excursions with the Institute of Microbiology, where I had the chance to learn mushroom identification from leading Czech mycologists. And unlike “typical pickers,” I often collect gilled mushrooms. My three-year-old granddaughter Anička might actually be able to name more bolete species than I can.<h4>Does your knowledge of chemistry help with identifying lesser-known species?</h4>No.&nbsp;<h4>Do you have a favorite mushroom – either for eating or just because it’s interesting?&nbsp;</h4>Aside from magic mushrooms, I have a soft spot for the fly agaric. Amanita muscaria, with its unmistakable red cap and white spots, has a rich and ancient history. Its story intersects with folk medicine and shamanism across many cultures, especially in the Northern Hemisphere. Another mushroom worth mentioning is the deadly Cortinarius orellanus. It grows in our region and can unfortunately be confused with some edible species. It contains the nephrotoxin orellanine, which is dangerous due to its delayed onset – symptoms can appear up to three weeks after ingestion, which makes treating the poisoning extremely difficult.&nbsp;<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Watrex_19_6_obr_2_02794e1777.jpg" alt="Watrex Fig.2: Illustrative photo of Amanita muscaria and Cortinarius orellanus" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Watrex_19_6_obr_2_02794e1777.jpg 245w," sizes="100vw" width="1600" height="839"><h4>What can we learn about a mushroom in a laboratory — apart from whether it’s edible or not?&nbsp;</h4>A mushroom, as a subject of laboratory study, can be analyzed taxonomically; we can identify substances that are toxicologically significant, search for new biologically active compounds, or use fungi as model organisms in genetic research. Their bioaccumulation capacity can help monitor unwanted substances in the environment. And I’m sure there are many other possibilities for scientific investigation in the lab.&nbsp;<h4>Have you ever examined the presence of toxins, heavy metals, or pesticides? How common are they in mushrooms?&nbsp;</h4>The ability of mushrooms to accumulate foreign substances is well documented and stems from the way they absorb nutrients from their surroundings. Their mycelium has a huge surface area and absorbs not only nutrients from the soil solution, but also unwanted substances, which may then accumulate in the fruiting bodies. I personally haven’t focused on bioaccumulation research in fungi — with one exception. After the Chernobyl nuclear disaster, we collected various mushroom species to monitor levels of Cesium-137.&nbsp;<h4>What’s your opinion on identifying mushrooms using mobile apps?&nbsp;</h4>If a mobile app serves as a replacement for a quality, well-illustrated mushroom atlas, I have no objections. However, I’d be very cautious when using various "identification keys." An amateur can easily overlook or misinterpret an important feature that differentiates an edible mushroom from an inedible or even poisonous one. That said, with the advancement of AI, things will surely improve :). As always — only collect mushrooms you can identify with absolute confidence!&nbsp;<h4>What’s something every mushroom hunter should know — but often overlooks?</h4>Where north is — and how to get back to the train station or their parked car.<h4>Besides a knife, is there anything else you’d bring in your mushroom basket?&nbsp;</h4>A camera. Mushrooms are incredibly photogenic. And if one doesn't end up in the basket, it can at least become a model for photography.&nbsp;<h4>And finally: If you had to describe mushrooms in one word, what would it be?</h4>Saprophytes. Without them, life on our planet would come to a halt.&nbsp;Many thanks to Roman Kysilka for such an open and inspiring conversation. It was a pleasure to explore his professional journey and the unique experiences that have shaped it. Roman currently works at <a target="_blank" rel="noopener noreferrer" href="https://watrex.com/?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_clanky">Watrex Praha</a>, where his expertise and experience continue to make a valuable impact. We wish him all the best in his future professional and personal endeavors!

Are you scientifically prepared for the new mushroom-picking season?

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For more than 40 years, ALS has provided testing and technical solutions to clients all over the world in a wide range of industries. We have built our global reputation by embracing the latest technologies and innovative methodologies to deliver high quality testing services to clients. ALS is able to leverage a multifaceted international team while remaining agile enough to provide local expertise and personalized solutions to every one of our clients.

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Organomation, founded in 1959, designs and manufactures high-quality nitrogen evaporators and extraction systems. Known for innovation and durability, their lab instruments are used globally for efficient sample preparation with strong customer support.

Organomation

WATREX Prague is the distributor and producer of HPLC techniques in the Czech Republic and Slovakia. Main Chromatografic and Related Techniques Supported: LC, GPC, IC, IEC, Automated SPE, LC Columns and special column packings, LC method development, Software development, Laboratory Robots.

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Phenomenex

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<h5>Key Learning Points:</h5><ul><li>Understand best practices upon opening a new LC Column</li><li>Learn how to clean and regenerate an LC Column</li><li>Find out about additional products and practices that can be used to minimize contamination getting onto LC columns</li></ul><h5>Who Should Attend:</h5><ul><li>Any LC user who would like to ensure that their LC columns are properly cared for to make sure to get most life out of it that is possible.</li></ul><blockquote>Presenter: Genevieve Hodson (Senior Manager, Technical Support &amp; Applications, Phenomenex)Genevieve graduated from the University of Texas with a BS in Chemistry located in her home town of Austin Texas. She spent 2 years of her undergraduate performing research in an Organic Chemistry Lab synthesizing intermediates. Out of school she spent 4 years as an Analytical Chemist in the QC and R&amp;D Department of Cerilliant (a Sigma Millipore Company). There she worked with many analytical instruments but became an expert at LC by performing purity analysis, customer specific methods, validations, qc testing and stability studies on a wide range of small molecules including pharmaceuticals, pesticides, explosives and illegal substances. From there she moved to Los Angeles California where she worked at Johnson and Johnson and then a small dietary supplement company. After Genevieve spent a year living abroad in Israel raising her first son, she moved back to LA where she got hired as a Technical Specialist at Phenomenex. At Phenomenex she enjoys continuing to learn about chromatography every day through helping customer with all their chromatography needs!</blockquote>

Phenomenex: How to Take Care of Your LC Column

How to Take Care of Your LC Column

Learn about the best practices upon opening your new LC Column, how to clean and regenerate, and additional products and practices...

<div><div>Let's go back to the Basics of Chromatography, Mass Spectrometry, Data Analysis and Trouble-shooting: understanding the importance of the basics will enable you to be more effective in your daily laboratory life.This journey started in 2024 and we are now pleased to invite you to join us to go deeper in fundamentals, troubleshooting and application specific topics.<h3>EPISODE 6: A question of Perspective - Nitrosamines Analysis</h3>What will you learn?<ul><li>Simple workflows to quantify N-Nitrosamines</li><li>Apply the latest regulations for Pharmaceuticals</li><li>A new perspective – with analyses in Food</li></ul>What's next?<ul><li>Check out the full Webinar Series Episodes List <a target="_blank" rel="noopener noreferrer" href="https://event.on24.com/eventRegistration/EventLobbyServlet?target=reg20.jsp&amp;eventid=4817889&amp;sessionid=1&amp;key=B9182AE813B3F8A30217606156F96B75&amp;groupId=5901784&amp;sourcepage=register">here</a></li></ul>Not sure to be able to attend live sessions?&nbsp;<ul><li>Register today and watch the webinars on-demand</li></ul><blockquote>Presenter: Antonia Wierzbicki (Principal MS Market Dev Manager, EMEA, Waters Corporation)Antonia Wierzbicki is a MS market development manager at Waters working in EMEA. Antonia has BSc in Pharmaceutical Science and a MSc in Cancer Pharmacology. Following several years working as an analytical chemist in drug development roles within both academic labs and contract research organizations, Antonia has more recently spent time working with analytical chemists to provide solutions using cutting edge technologies to meet their needs and requirements, with a specific interest in ultra-sensitive quantitation of small molecules. Antonia is based in Cambridge UK and keen to connectwith like-minded scientists in the field.Presenter: Caroline Davis (Senior Sales Application Chemist, Waters)Caroline is part of the Customer Success team at Waters with a focus on LC-MS/MS application and sales support. She works in this role for more than 5 years. Caroline has a strong background in environmental science. She finished her PhD in Environmental Chemistry at ETH Zurich / EAWAG after getting a Bachelor in Chemistry at San Diego State University, US, and a Master in Structural Chemistry and Spectroscopy at Universität Leipzig, Germany.</blockquote></div></div>

Waters Corporation: Back to Basics Advanced Webinar Series 2025

Back to Basics Advanced - Contaminants: Nitrosamines

Simple workflows to quantify N-Nitrosamines. Apply the latest regulations for Pharmaceuticals. A new perspective – with analyses in Food.

<div><div>Let's go back to the Basics of Chromatography, Mass Spectrometry, Data Analysis and Trouble-shooting: understanding the importance of the basics will enable you to be more effective in your daily laboratory life.This journey started in 2024 and we are now pleased to invite you to join us to go deeper in fundamentals, troubleshooting and application specific topics.<h3>EPISODE 7: Importance of PFAS Analyses Prepare For All inSights</h3>What will you learn?<ul><li>Overview on Sample Prep Methods</li><li>Absolute Sensitivity for the know PFAS</li><li>Approaches to find the unknown PFAS</li></ul>What's next?<ul><li>Check out the full Webinar Series Episodes List <a target="_blank" rel="noopener noreferrer" href="https://event.on24.com/eventRegistration/EventLobbyServlet?target=reg20.jsp&amp;eventid=4817889&amp;sessionid=1&amp;key=B9182AE813B3F8A30217606156F96B75&amp;groupId=5901784&amp;sourcepage=register">here</a></li></ul>Not sure to be able to attend live sessions?&nbsp;<ul><li>Register today and watch the webinars on-demand</li></ul><blockquote>Presenter: Kari Organtini, PhD (Principal Scientist, Waters Corporation)Kari Organtini is a principal scientist at Waters Corporation and has been with the company for eight years. She received her PhD from Penn State University in 2015 studying the occurrence of dioxins and furans in fire debris and their implications to first responder health. At Waters, Kari is part of the PFAS Program in the Testing and Lab Services Group. Kari has developed applications using both LC and GC techniques for a variety of applications ranging from pesticides to persistent organic pollutants during her career. She is currently the scientific lead for developing PFAS applications at Waters.Presenter:&nbsp;Mike McCullagh PhD (Principal Consulting Scientist, MS Discovery Program, Waters Corporation)Mike joined Waters Corporation in 2001 and has performed a variety of roles at the company in science, applications and marketing areas. With a strong background in time-of-flight mass spectrometry and ion mobility Mike has experience in several application areas, including; impurity profiling, natural product profiling, authentication profiling and pesticide/veterinary residue screening. With his experience in instrumentation, applications and extensive customer collaborations Mike has a deep understanding of customer challenges and develops new applications strategies and supports instrument development to ensure customers success.</blockquote></div></div>

Back to Basics Advanced - Contaminants: PFAS

Overview on Sample Prep Methods. Absolute Sensitivity for the know PFAS. Approaches to find the unknown PFAS.

<div><div>Let's go back to the Basics of Chromatography, Mass Spectrometry, Data Analysis and Trouble-shooting: understanding the importance of the basics will enable you to be more effective in your daily laboratory life.This journey started in 2024 and we are now pleased to invite you to join us to go deeper in fundamentals, troubleshooting and application specific topics.<h3>EPISODE 8: Proteins &amp; Peptides Analysis</h3>What will you learn?<ul><li>Learn about the Newest Innovations in Columns and Detection Technologies for Proteins and Peptides</li><li>Discover the waters_connect world of Dedicated Automated Workflows</li></ul>What's next?<ul><li>Check out the full Webinar Series Episodes List <a target="_blank" rel="noopener noreferrer" href="https://event.on24.com/eventRegistration/EventLobbyServlet?target=reg20.jsp&amp;eventid=4817889&amp;sessionid=1&amp;key=B9182AE813B3F8A30217606156F96B75&amp;groupId=5901784&amp;sourcepage=register">here</a></li></ul>Not sure to be able to attend live sessions?&nbsp;<ul><li>Register today and watch the webinars on-demand</li></ul><blockquote>Presenter: Antonia Wierzbicki (Principal MS Market Dev Manager, EMEA, Waters Corporation)&nbsp;Antonia Wierzbicki is a MS market development manager at Waters working in EMEA. Antonia has BSc in Pharmaceutical Science and a MSc in Cancer Pharmacology. Following several years working as an analytical chemist in drug development roles within both academic labs and contract research organizations, Antonia has more recently spent time working with analytical chemists to provide solutions using cutting edge technologies to meet their needs and requirements, with a specific interest in ultra-sensitive quantitation of small molecules. Antonia is based in Cambridge UK and keen to connectwith like-minded scientists in the field.Presenter:&nbsp;Andrea Gheduzzi (Principal LC Market Dev. Manager, EMEA, Waters Corporation)Andrea Gheduzzi, is a principal LC market development manager for EMEA at Waters Corporation. Andrea Gheduzzi has spent more than 30 years in the chromatography field. Across his career he had various roles, service engineer, chromatography lab manager position, and technical manager for chromatography columns. He has mainly been dealing with pharma accounts, also supporting LC method development activities using DoE/QbD approaches. In his previous role as Pharma Business Development Manager at Waters he has further expanded his expertise in AQbD and related applications. Since 2023 he became principal LC market development manager for EMEA and member of the AQbD working party at the EDQM.Presenter:&nbsp;Ben Wilkes (Principal Biologics Market Development Manager, Waters Corporation)Since 2022, Ben Wilkes is a Principal Biologics Market Development Manager at Waters where he connects biotech companies with enabling analytical technologies, focusing on liquid chromatography and mass spectrometry. Prior to Waters, Ben worked at Lonza Biologics from 2015 to 2022 as an analytical R&amp;D scientist, supporting all aspects of a products lifecycle with novel analytical methods. He also previously worked at Abzena and Sanofi-Genzyme after graduating from the University of Manchester in 2012</blockquote></div></div>

Back to Basics Advanced - Biologics: Proteins & Peptides

Learn about the Newest Innovations in Columns and Detection Technologies for Proteins and Peptides. Waters_connect world of Dedicated Automated Workflows.

<div><div>Let's go back to the Basics of Chromatography, Mass Spectrometry, Data Analysis and Trouble-shooting: understanding the importance of the basics will enable you to be more effective in your daily laboratory life.This journey started in 2024 and we are now pleased to invite you to join us to go deeper in fundamentals, troubleshooting and application specific topics.<h3>EPISODE 9: How to Analyze RNA &amp; Oligonucleotides</h3>What will you learn?<ul><li>End-to-end Sequence Mapping and CQA Monitoring Workflows</li><li>LNP Characterization and Monitoring</li></ul>What's next?<ul><li>Check out the full Webinar Series Episodes List <a target="_blank" rel="noopener noreferrer" href="https://event.on24.com/eventRegistration/EventLobbyServlet?target=reg20.jsp&amp;eventid=4817889&amp;sessionid=1&amp;key=B9182AE813B3F8A30217606156F96B75&amp;groupId=5901784&amp;sourcepage=register">here</a></li></ul>Not sure to be able to attend live sessions?&nbsp;<ul><li>Register today and watch the webinars on-demand</li></ul><blockquote>Presenter: Antonia Wierzbicki (Principal MS Market Dev Manager, EMEA, Waters Corporation)&nbsp;Antonia Wierzbicki is a MS market development manager at Waters working in EMEA. Antonia has BSc in Pharmaceutical Science and a MSc in Cancer Pharmacology. Following several years working as an analytical chemist in drug development roles within both academic labs and contract research organizations, Antonia has more recently spent time working with analytical chemists to provide solutions using cutting edge technologies to meet their needs and requirements, with a specific interest in ultra-sensitive quantitation of small molecules. Antonia is based in Cambridge UK and keen to connectwith like-minded scientists in the field.Presenter:&nbsp;Andrea Gheduzzi (Principal LC Market Dev. Manager, EMEA, Waters Corporation)Andrea Gheduzzi, is a principal LC market development manager for EMEA at Waters Corporation. Andrea Gheduzzi has spent more than 30 years in the chromatography field. Across his career he had various roles, service engineer, chromatography lab manager position, and technical manager for chromatography columns. He has mainly been dealing with pharma accounts, also supporting LC method development activities using DoE/QbD approaches. In his previous role as Pharma Business Development Manager at Waters he has further expanded his expertise in AQbD and related applications. Since 2023 he became principal LC market development manager for EMEA and member of the AQbD working party at the EDQM.Presenter:&nbsp;Ben Wilkes (Principal Biologics Market Development Manager, Waters Corporation)Since 2022, Ben Wilkes is a Principal Biologics Market Development Manager at Waters where he connects biotech companies with enabling analytical technologies, focusing on liquid chromatography and mass spectrometry. Prior to Waters, Ben worked at Lonza Biologics from 2015 to 2022 as an analytical R&amp;D scientist, supporting all aspects of a products lifecycle with novel analytical methods. He also previously worked at Abzena and Sanofi-Genzyme after graduating from the University of Manchester in 2012</blockquote></div></div>

Back to Basics Advanced - Biologics: RNA & Oligonucleotides

End-to-end Sequence Mapping and CQA Monitoring Workflows. LNP Characterization and Monitoring.

This presentation will cover the basic operation of metal speciation by the coupling of chromatography technique with ICPMS. This hybrid analytical technique provides lower detection limits in metal containing compound when compared to LCMS techniques. Some of the tips and tricks will also be discussed in this presentation.&nbsp;<blockquote>Presenter: Yan Cheung, PhD (Application Scientist, Agilent Technologies, Inc.)Yan received her Ph.D. in Analytical Chemistry from Indiana University Bloomington. She joined Agilent Technologies as an Application Scientist in the Life Science and Chemical Analysis team in April 2020. Yan has extensive experience in operating and method development in ICP-MS. Yan also has years of experience working in the oil and gas industry.</blockquote>

Agilent Technologies: Overview of Metal Speciation by LC/IC-ICPMS

Overview of Metal Speciation by LC/IC-ICPMS

This presentation will cover the basic operation of metal speciation by the coupling of chromatography technique with ICPMS. 

<div>Dynamic Light Scattering (DLS) is a powerful and established technique for determining the size of submicron particles, including proteins, liposomes, nanoparticles, and compound aggregates. Widely used in biotherapeutic development, DLS provides critical insights into size, aggregation, and stability throughout the research and formulation pipeline.This webinar will introduce the fundamentals of DLS and explore its practical applications in biopharmaceutical workflows—from formulation optimization to accelerated stability testing. Special emphasis will be placed on high-throughput DLS using the DynaPro™ Plate Reader instrument, which enables automated screening of sample conditions such as buffer composition, concentration, temperature, and time-based stability directly in disposable microwell plates.<h5>Key Learning Objectives:</h5><ul><li>An introduction/review of Dynamic Light Scattering (DLS)</li><li>Understanding kD and A2 stability metrics</li><li>Example applications including formulation development and stability</li></ul><h5>Who Should Attend:</h5><ul><li>Scientists and Researchers working in biopharmaceuticals, particularly those involved in biologic drug development, formulation, and characterization</li><li>Lab Managers looking to understand state-of-the-art instruments for enhancing analytical capabilities in their labs</li><li>Learners and Newcomers eager to gain a foundational understanding of dynamic light scattering (DLS) for applications in biopharmaceuticals &nbsp;</li></ul><blockquote>Presenter: Paul Velander, Ph.D. (Waters | Wyatt Technology)Paul joined Wyatt Technology in 2022 and currently serves as an Application Scientist on the Customer Support team, as well as the Dean of our Light Scattering University training program. Paul completed his Ph.D. in Biochemistry at Virginia Tech, with a focus on small molecule drug discovery against toxic amyloid aggregation pathways. Before joining Wyatt, Paul spent time at the University of Nebraska-Lincoln, where he served as a postdoctoral associate and assistant professor. His research during this time primarily focused on developing murine model systems to investigate gut microbiome associations with heart disease. He now provides consultation and training for customers across a broad array of fields and is responsible for advanced training for our field scientists and Wyatt representatives worldwide.</blockquote></div>

Waters Corporation: Fundamentals and Applications of Dynamic Light Scattering (DLS) for Biotherapeutic Development

Fundamentals and Applications of Dynamic Light Scattering (DLS) for Biotherapeutic Development

This webinar will introduce the fundamentals of DLS and explore its practical applications in biopharmaceutical workflows

DLS Fundamentals for Biotherapeutic Development

<h4>Overview</h4>In this presentation, we will cover the following key topics:<ul><li>Fundamental principles of retention in liquid chromatography (LC)</li><li>Understanding void time and retention factors</li><li>Exploring the relationship between retention factor and resolution</li><li>Strategies for addressing common challenges in retention time and resolution</li></ul><h4>Key Learning Points</h4><ul><li>Understand how compounds are retained in LC&nbsp;</li><li>Learn the difference between retention time and retention factor, and the importance of the void time&nbsp;</li><li>Find how retention influences resolution&nbsp;</li><li>Gain insight how to influence retention and resolution to solve or prevent issues&nbsp;</li></ul><h4>Who Should Attend</h4><ul><li>Any HPLC user who is currently facing issues with retention times and/or resolution in developing or troubleshooting their method, or who want to prevent these issues later.</li></ul><blockquote>Speaker: Koen Askamp (Technical Specialist)Koen Askamp is a Technical Specialist in Phenomenex. He was awarded his BSc and MSc degrees in Molecular Life Sciences at Wageningen University in the Netherlands and joined Phenomenex in 2020 as Technical Sales Consultant. Koen became part of Phenomenex’s global technical support team in 2022 and assists laboratories in training chromatographers and developing analytical methods.</blockquote>

Phenomenex: HPLC Mysteries Unveiled: Solving Retention Time and Resolution Challenges

HPLC Mysteries Unveiled: Solving Retention Time and Resolution Challenges

Learn how retention and resolution work in LC. Understand void time, retention factors, and practical tips to troubleshoot or prevent HPLC method issues.

HPLC Solving Retention Time and Resolution Challenges

<h4>Key Learning Points</h4><ul><li>Recieve an overview of chromatography modes and how they works. Normal Phase, Reversed Phase, HILIC, Ion Exchange, Ion Exclusion, Size Exclusion (GPC/GFC).&nbsp;</li><li>Develop the ability to distinguish between various chromatography modes</li><li>Tune in for a refresher on the basic theory of HPLC</li></ul><h4>Who Should Attend</h4><ul><li>This webinar is designed for any new LC users, this provides a foundational understanding of HPLC, with a focus on chromatographic modes.</li></ul><blockquote>Speaker: Duilio Romanello (Senior Technical Specialist)Duilio Romanello graduated with his Bachelors of Science in Pharmaceutical Chemistry and Technology from University of Bologna. Duilio then joined Phenomenex in 2008 as an Inside Technical Sales Consultant becoming Team Leader in Italy for GC/SPE in 2010 and then for the Env/Food Team. Since 2016 he has been covering the role of Account Manager for the South of Italy working remotely and acting as GC Specialist. Since November 2023 he is Senior Technical Specialist for the Technical team at Phenomenex.</blockquote>

Phenomenex: Chromatography Modes Explained: Dive into the Modes of Chromatography!

Chromatography Modes Explained: Dive into the Modes of Chromatography!

New to LC? Learn the basics of HPLC and explore key chromatography modes like RP, NP, HILIC, IEC, IEX, and SEC in this beginner-friendly webinar.

Chromatography Modes Explained

Join this webinar to learn from our experts about the power of capillary electrophoresis (CE) analysis and how it can provide benefit to your research. No matter your level of CE knowledge, the session will shine a light on this technique and showcase its applicability across various industries. Our speakers will outline how to develop methods for protein characterization, RNA/DNA analysis and small molecule detection and discuss some of the innovative integrated CE technologies. Using real examples we will demonstrate what is possible to achieve with the range of CE consumable kits available.<blockquote>Presenter: Dr. Sarah Meyer (Regional Service Specialist, SCIEX)Sarah earned her doctorate in Analytical Chemistry in 2022. Her research focused on bioanalytical applications, particularly investigating the effectiveness of radiotherapy in cancer treatment. She developed high-resolution separation methods and novel mass spectrometry-based detection approaches to enhance analytical sensitivity. That same year, Sarah joined SCIEX as a Regional Specialist for Capillary Electrophoresis in the Asia-Pacific region, supporting teams and customers with technical and analytical challenges.Presenter:&nbsp;Dr Charlie Liu (Field Applications Specialist, SCIEX) Charlie obtained his PhD in biopolymers in 2014. He has experience as an analytical chemist and as a chemistry department manager at Biotest Laboratories and BJP Laboratories where he gained expertise in method development and validation in analytical chemistry, especially LC-MS/MS. In 2021, Charlie joined SCIEX Oceania as a Field Application Specialist focusing on pharmaceutical, food and environmental applications.Presenter:&nbsp;Jeremy Potriquet (Field Applications Specialist, SCIEX) Jeremy has extensive knowledge of peptide and protein analysis and quantification from previous roles as a scientific officer and proteomics manager. He is experienced in processing a variety of sample matrices ranging from cancer-related matrices to those for infectious diseases covering the study of exosomes, parasites, venoms and lately immunology. Mass spectrometry has always been an essential part of &nbsp;Jeremy's career and with SCIEX as a Field Application Specialist, he applies his knowledge to provide support and guidance for the numerous SCIEX technology users in ANZ.</blockquote>

SCIEX: Capillary electrophoresis applications

Capillary electrophoresis applications

Join this webinar to learn from our experts about the power of capillary electrophoresis (CE) analysis and how it can provide benefit to your research.

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