In forensic toxicology, understanding what is in a sample and how much of it is there, quickly, accurately, and confidently, can make all the difference. Whether it is an overdose investigation, a sudden death case, or surveillance for emerging public health risks, laboratories are under pressure to deliver high-quality results with tighter turnaround times and broader analytical scope.That is where high-resolution, accurate-mass (HRAM) <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=134&amp;manufacturerItems=3">Orbitrap mass spectrometry</a> really shines, especially when paired with streamlined workflows and intelligent data analysis.<h3>What’s new?</h3>A recent <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/tn_002551_cl_phsa_orbitrap_forensic_tn002551_na_en_a34276b79b.pdf">Technical Note (TN-002551) </a>details a rapid LC-HRAM-Orbitrap method developed collaboratively with the B.C. Provincial Toxicology Centre for postmortem blood analysis. This workflow was designed to deliver routine screening and quantitation while also enabling retrospective data mining to identify unknown or emerging compounds in circulation.Here is what makes this approach compelling:<ul><li>High sensitivity and resolution: The Thermo Scientific Q Exactive HF hybrid quadrupole-Orbitrap system enables faster scan speeds and precise mass measurement, which boosts confidence in detecting drugs, even at low levels, in complex postmortem matrices.</li><li>Robust routine productivity: Running routine screens in approximately 12.5 minutes significantly speeds workflow throughput, which is critical as labs face growing caseloads.</li><li>Retrospective analysis: One of the biggest advantages of HRAM data is the ability to re-interrogate stored data files for novel psychoactive substances after the initial screen is complete. This capability eliminates the need to re-run samples, saving time and preserving limited sample material.</li></ul>A standout example from the technical note was the identification of bromazolam, a designer benzodiazepine that was not part of the original routine panel. Through retrospective analysis, its prevalence in postmortem cases was revealed and quantified, demonstrating the real-world value of full-scan HRAM data.<h5>Supporting broad drug panels</h5>As highlighted in a previous THC tips and tricks blog post, cannabinoids and their metabolites can be challenging when analyzed alongside other drugs of abuse. HRAM MS improves selectivity and confidence when multiple drug classes are analyzed together, making it easier to integrate THC and related compounds into comprehensive toxicology workflows.<h5>Why this matters for forensic toxicology today</h5>The opioid crisis, the continued emergence of novel psychoactive substances, and evolving public health threats demand analytical tools that are both robust and adaptable. HRAM Orbitrap LC-MS not only improves detection and quantitation across a wide range of drugs of abuse, but also enables:<ul><li>Retrospective discovery of unknown compounds</li><li>Faster delivery of actionable results to coroners and public health agencies</li><li>Improved surveillance of emerging drug trends</li></ul>As toxicology laboratories look to future-proof their operations, combining powerful instrumentation, intelligent software, and optimized workflows will be key. Methods like those described in TN-002551 demonstrate how HRAM Orbitrap mass spectrometry continues to elevate forensic toxicology workflows.<h3>Resources</h3><ul><li>Featured technical note: <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/tn_002551_cl_phsa_orbitrap_forensic_tn002551_na_en_a34276b79b.pdf">Rapid, high-resolution postmortem toxicology analysis using Orbitrap mass spectrometry</a></li><li>Previous blogs in this series:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/6189">Sample Preparation Strategies for Toxicology Workflows</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/6587">Beyond Blood: HRAM-Powered Postmortem Toxicology at Sheffield Teaching Hospitals</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/6860">Advancing Drug Analysis with VeriSpray PaperSpray Mass Spectrometry</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/6953">Boosting Productivity in Toxicology Labs</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/7190">Behind the Bench: Tips to Simultaneously Analyze THC, Its Metabolites, and Other Drugs of Abuse</a></li></ul></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/content/lifetech/global/en/home/industrial/forensics/forensic-toxicology.html">Forensic toxicology webpage</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/content/lifetech/global/en/home/industrial/mass-spectrometry/mass-spectrometer-price-affordability-programs.html">Affordability resources</a></li></ul><blockquote>Visit us on&nbsp;<a target="_blank" rel="noopener noreferrer" href="https://www.linkedin.com/showcase/72003132/admin/dashboard/">LinkedIn:</a>&nbsp;#PostmortemAnalysis #HRAMOrbitrapMS #ForensicToxicology #NPS</blockquote>

Sharper, Faster, Smarter: HRAM Orbitrap Mass Spectrometry Meets Postmortem Toxicology

We are pleased to invite you to our upcoming free online webinar on June 11, 2026 focused on one of the most pressing challenges in environmental monitoring and water quality management — PFAS (Per- and Polyfluoroalkyl Substances).As regulatory frameworks continue to evolve and compliance deadlines approach, laboratories, water utilities, and environmental professionals need robust, reliable, and cutting-edge analytical solutions to stay ahead.<blockquote>👉<a target="_blank" rel="noopener noreferrer" href="https://events.teams.microsoft.com/event/91d97003-fe33-4dca-b80b-160d9f8a5655@485ca04e-6f74-4050-9764-cdb4bfa89c25">Registration HERE</a></blockquote><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ALS_analyzy_PFAS_a9e4a87fbc.jpg" alt="ALS: Advanced PFAS Analytical Services " srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ALS_analyzy_PFAS_a9e4a87fbc.jpg 245w," sizes="100vw" width="600" height="336"><h4>🎤 Our Speaker</h4>The webinar will be hosted by Jana Kováčová, Ph.D., PFAS Regional Lead for Continental Europe Environmental Division, who has dedicated the last several years to the field of PFAS analysis and determination in ALS laboratories. Jana is a recognized expert in PFAS environmental analytics and will share practical insights and the latest developments in analytical strategies to help your organization achieve and maintain compliance.<h4>🎯 What You Will Learn</h4><ul><li>Latest regulatory developments and compliance requirements for PFAS in water, including EU Drinking Water Directive 2020/2184 and its implications for water suppliers and laboratories.</li><li>Regulatory updates for surface water and groundwater — what's new and what to expect next.</li><li>Overview of advanced analytical strategies for PFAS detection and quantification in water matrices and how we analyse PFAS samples.</li><li>Key analytical challenges associated with PFAS testing — from ultra-trace detection to matrix interferences and contamination control.</li><li>The critical importance of using tested sampling containers and sample preservation to ensure reliable results.</li><li>Illustrative examples of results from real-world PFAS water analyses.</li><li>How ALS can support your needs with accredited PFAS testing services.</li></ul><h4>👥 Who Should Attend</h4>This webinar is designed for our clients, professionals, laboratory and technical staff, scientists, as well as anyone with an interest in analytical chemistry who wants to better understand the occurrence of these "forever chemicals" in the environment. &nbsp;<h4>💬 Q&amp;A Session</h4>There will be a live Q&amp;A session at the end of the webinar. You are welcome to submit your questions in advance during registration or ask them live on the day.<h4>📅 Additional Webinar Info:</h4><ul><li>Platform: Microsoft Teams (online)</li><li>Time: 10:00 CEST</li><li>Language: English</li><li>Duration: approx. 45 - 60 minutes (incl. Q&amp;A) Extras: If you are unable to attend on the day, please register and we will provide you with the recording of the webinar.</li></ul><h4>🔬 About ALS Environmental</h4>ALS is a global leader in environmental testing and analytical services, providing accredited PFAS analysis to clients across Europe and beyond. Our dedicated PFAS experts help clients navigate the complex regulatory landscape with confidence.<blockquote>For further information, please contact us on: marketing.cz@alsglobal.com</blockquote>We look forward to welcoming you to this important discussion on PFAS compliance in water.

Invitation to the ALS Webinar PFAS in Water 2026: Achieving Compliance through Advanced Analytical Strategies

ISC 2026 Keynote Lectures

Article

Events

Webinars

Video

Scientists

Water

Toxicology

Science and research

For more than 40 years, ALS has provided testing and technical solutions to clients all over the world in a wide range of industries. We have built our global reputation by embracing the latest technologies and innovative methodologies to deliver high quality testing services to clients. ALS is able to leverage a multifaceted international team while remaining agile enough to provide local expertise and personalized solutions to every one of our clients.

ALS Czech Republic

A unique company dedicated to serving science helping our customers drive productivity and accelerate results. Through our premier brands – Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific and Unity Lab Services.

Thermo Fisher Scientific

The International Symposium on Chromatography (ISC) represents the oldest conference series focussing on separation science. ISC symposia have been organised since 1956 in each even year. ISC is internationally recognised as one of the premier meeting series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.

International Symposium on Chromatography - (ISC)

Agilent Technologies

Bruker

Phenomenex

Shimadzu Corporation

Waters Corporation

<h3>Solving Problems That Matter - a Waters webinar series featuring USP speakers</h3><h4>Episode 8: Lipid nanoparticles</h4><div class="summary-section section">Developing safe, compliant and efficacious lipid nanoparticles (LNP) requires adequate testing of the individual lipid components and impurities. In this webinar Anni Chang from the USP Excipient team will share current and future excipient solution approaches and describe how the USP provides support for stakeholders in discovery and early-stage development. Then Duanduan Han will discuss the benefits of mass detection for critical impurities analysis, and Empower software workflows for compliant and straightforward method migration from development to QC labs. Duanduan will also highlight how multi-angle light scattering (MALS) detection can be used to characterize the LNP.<h5>Key learning objectives</h5><ul><li>Explore current and future USP solutions for lipid nanoparticles (LNP)</li><li>Learn how mass detection and Empower software-based workflows expedite and enhance routine testing of LNP components and impurities</li><li>Discover orthogonal insights enabled by multi-angle light scattering detection (MALS)</li></ul><h5>Who should attend</h5>Scientists involved with lipid nanoparticle analysis<blockquote>Presenter: Anni Chang, Ph.D. (Sr Scientist II, Excipients Unit, US Pharmacopeia)Dr. Anni Chang is currently a Senior Scientist II in the Excipients unit at the United States Pharmacopeia (USP). In her current role, she is responsible for developing, revising, and modernizing USP monographs. One of her focus areas is lipid excipients used in nanomaterial carriers.Dr. Chang has more than 15 years of experience in the biotech/pharmaceutical industry in analytical method development, validation, and transfer. She received her Ph.D. in Chemistry from University of Maryland, College Park, Maryland, USA. Dr. Chang is also active in the American Association of Pharmaceutical Scientists and serves as a Member Engagement Manager in the Lipid Based Drug Delivery community.Presenter: Duanduan Han, Ph.D. (Senior Scientist QA/QC Biologics Solutions group, Waters Corporation)Duanduan is a Senior Scientist in the QA/QC Biologics Solutions group at Waters Corporation headquarters in Milford, MA. She joined Waters in 2021, and she has focused on LC method development in composition analysis, impurity profiling, and raw material screening of lipid nanoparticle components and products. Additionally, she has explored other subjects of pharmaceutical analysis including surfactant, protein, and peptide. Prior to joining Waters, she received her PhD in chemical engineering from Texas A&amp;M University.Presenter: Panelist: Martin Kurnik, Ph.D. (Senior Scientist, Analytical Sciences, Waters | Wyatt Technology​)Martin Kurnik is a senior scientist in the Analytical Sciences team at Waters | Wyatt Technology. He helps customers identify and develop the best solutions for their analytical needs by leveraging his expertise in multi-angle light scattering and dynamic light scattering as well as a wide range of other leading techniques for biomolecular characterization. His postdoctoral research in protein folding and misfolding biophysics focused on understanding and preventing misfolding in bulk solution and on artificial surfaces used in medicine and biotechnology, and he has also developed protein- and aptamer-based electrochemical biosensors for continuous real-time measurements in vitro and in vivo. Martin received his M.Sc. in Chemistry and Ph.D. in Biochemistry from Stockholm University, Sweden.Moderated by: Isabelle Vu Trieu (Pharmaceutical Market Development Manager, Americas, Waters Corporation)Isabelle is a business development professional dedicated to delivering benefits to analytical scientists in the life sciences industry. With over 20 years of experience in providing chromatography and mass spectrometry solutions, Isabelle is particularly interested in helping pharmaceutical scientists achieve the data quality and integrity needed to drive decisions for drug quality, safety and efficacy. Isabelle joined Waters in 2009 and currently manages the development of the pharmaceutical market in the Americas. She holds Masters’ degrees in Chemistry from Columbia University and the University Claude Bernard in Lyon, France as well as a Chemical Engineering degree from Ecole Supérieure de Chimie Physique Electronique in Lyon, France.</blockquote></div>

Waters Corporation: Solving Problems That Matter - a Waters webinar series featuring USP speakers

Lipid nanoparticles

Solving Problems That Matter - a Waters webinar series featuring USP speakers. Episode 8: Complex excipients: Lipid nanoparticles.

Complex excipients: Lipid nanoparticles

Delivering connected science for your lab evolution
In the fast-paced world of laboratory operations, staying ahead of regulatory changes, increasing demands, and fierce competition is essential. However, outdated instrumentation and software can often hinder your progress.
Our newly launched software is meticulously crafted to elevate laboratory efficiency and ensure reproducibility, all while minimising manual errors. One of the core tenets of our software is its user-friendly interface, designed with simplicity in mind. Here’s your opportunity to get firsthand experience!
<h3>AGENDA</h3>
<h5>09:00 Welcome + Coffee + Networking</h5>
<h5>09:30 Introduction to waters_connect: Delivering connected science for your lab evolution</h5>
<h5>09:45 Streamlining System Setup and Data Acquisition: Maximizing efficiency and accuracy</h5>
<h5>10:30 Coffee and networking opportunities</h5>
<h5>11:00 Compound optimization with just a few clicks - Hands-on workshop</h5>
<h5>11:45 Mastering MS Quan: Demonstration of next generation of data processing</h5>
<h5>12:30 Lunch</h5>
<h5>13:30 Mastering MS Quan: Unleash your analytical potential- hands-on workshop</h5>
<h5>15:30 General discussion, coffee and wrap-up</h5>

Waters Corporation: waters_connect for Quantitation workshop

waters_connect for Quantitation workshop

Here’s your opportunity to get firsthand experience.

MALDI Top-Down Sequencing (MALDI-TDS) delivers N- and C-terminal sequence readout for intact proteins or protein subunits within minutes.
Leverage the novel neofleX™ MALDI-TDS workflow for verification of therapeutic antibodies, antigens and other protein expression products regarding sequence, terminal status and modifications and, thereby, enable instant decision making in strain development and production in biopharma or other branches of industry.
During this webinar, you will learn:
<ul>
<li>Overview of neofleX technology and its benefits to life sciences applications
</li>
<li>neofleX top-down workflow: Protein sequence verification with shortest time-to-result
</li>
<li>OmniScape™ software: From data to sequencing results with just a few mouse clicks
</li>
</ul>
Who should attend:
<ul>
<li>Characterization team leaders in biopharma companies and CROs
</li>
<li>Mass spectrometry core lab managers
</li>
<li>Researchers who are interested in fast protein characterization methods
</li>
<li>Anyone who needs to deliver instant sequence verification for protein expression products
</li>
<li>Anyone who would like to learn about the latest MALDI-TOF/TOF technology
</li>
</ul>
<blockquote>
Presenter: Jan Hendrik Kobarg, Ph.D. (Product Manager, MALDI-TOF, Bruker Daltonics, Bremen, Germany)
</blockquote>
<blockquote>
Jan Kobarg, Ph.D., is the product manager for the MALDI-TOF instrument portfolio at Bruker. The latest addition to the portfolio is the neofleX™ MALDI-TOF Benchtop instrument.
</blockquote>
<blockquote>
Presenter: Arndt Asperger, Ph.D. (Senior Applications Scientist, Bruker Daltonics, Bremen, Germany)
</blockquote>
<blockquote>
Arndt is analytical chemist by training and got his Ph.D. from Leipzig University. He joined Bruker in 2002 and has been working in various application related positions with a focus on pharma/biopharma.
</blockquote>

Bruker: LabCast: Simple and fast top-down protein characterization using neofleX benchtop MALDI-TOF/TOF

LabCast: Simple and fast top-down protein characterization using neofleX benchtop MALDI-TOF/TOF

Overview of neofleX technology and its benefits to life sciences applications.

LabCast: Simple and fast top-down protein characterization

The sample throughput of high-sensitivity liquid chromatography-mass spectrometry (LC-MS) based proteomics analysis is restricted by the pressure limitations of LC and column hardware, with some methods wasting as much as 50% of the method cycle time outside of MS acquisition.
Traditional routes for boosting throughput include shorter columns and gradients, higher flow rates, and using trap-and-elute workflows – all of which introduce trade-offs in sensitivity and proteome depth.
The Thermo Scientific™ Vanquish™ Neo tandem direct injection workflow leverages hardware innovations and software intelligence to eliminate method overhead while maintaining data quality across nano, capillary, and micro-flow LC-MS.
In this webinar experts from Evotec and Bayer will showcase how they implemented the tandem direct injection workflow for their proteomics work. Dr. Nagarjuna Nagaraj will present on how Evotec is using tandem direct injection with nano-LC columns packed in-house to boost sample throughput of their chemoproteomics screening pipeline, while Dr. Alexander Boychenko from Bayer will discuss how his lab is using a micro-flow tandem direct injection approach to analyze plasma samples for translational proteomics.
Learning Objectives
<ul>
<li>See how minimizing LC-MS method overhead can accelerate sample throughput while maintaining proteome depth
</li>
<li>Discover how labs are using tandem direct injection for chemoproteomics and translational proteomics applications
</li>
<li>Learn how to implement tandem direct injection in your proteomics workflow
</li>
</ul>
<blockquote>
Presenter: Dr. Nagarjuna Nagaraj (Group Leader High Sensitivity Proteomics, Evotec)
</blockquote>
<blockquote>
Dr. Nagarjuna Nagaraj is a proteomics group leader at Evotec focusing on high sensitivity and high throughput proteomics applications with more than 18 years of experience in proteomics and mass spectrometry. Nagarjuna obtained his PhD from the Matthias Mann lab focusing on sample preparation and MS data acquisition strategies for clinical applications. After a postdoc he directed the mass spectrometry core facility at the Max-Planck-Institute of Biochemistry working on a wide range of protein and peptide mass spectrometry projects such as bottom-up proteomics, structural mass spectrometry including HDX, native and crosslinking MS, intact protein and small molecule analysis.
</blockquote>
<blockquote>
Presenter: Dr. Alexander Boychenko (Head of R&amp;D Laboratory Precision Medicine Markers, Bayer)
</blockquote>
<blockquote>
Alexander Boychenko is leading Omics Research within the Translational Sciences team of the Pharmaceuticals division at Bayer Group. He is focused on implementing innovative analytical technologies and developing novel methodologies for proteomics, metabolomics, and ligand-binding assays (LBA) to comprehensively characterize human and animal model phenotypes, enabling disease understanding and novel biomarker discovery. He holds a Ph.D. in Analytical Chemistry from Kharkiv National University, Ukraine. During his post-doctoral work at the University of Groningen, The Netherlands, he combined LC-MS and immunoassays to discover and validate protein biomarkers in biofluids for cancer screening. Before joining Research and Early Development at Bayer AG, he developed and introduced new liquid chromatography-mass spectrometry products at Thermo Fisher Scientific. Alexander is a subject matter expert in LC-MS, biological data interpretation, and precision medicine. He utilizes his passion for applying technical expertise to develop new medicines.
</blockquote>
<blockquote>
Presenter: Dr. Alec Valenta (Product Marketing Manager, Thermo Fisher Scientific)
</blockquote>
<blockquote>
Alec is the product marketing manager for the Vanquish Neo UHPLC system and low-flow LC columns. Prior to joining Thermo Fisher Scientific he earned his PhD in analytical chemistry from the University of Michigan where he helped advance microdialysis sampling of neurochemicals and developed LC-MS methods to quantify small molecule neurotransmitters, neuropeptides, and metabolites in a variety of complex biological samples.
</blockquote>

Thermo Scientific: A Tandem LC Workflow for Maximizing Mass Spectrometer Utilization in Proteomics

A Tandem LC Workflow for Maximizing Mass Spectrometer Utilization in Proteomics

How experts from Evotec and Bayer implemented the tandem direct injection workflow for their proteomics work.

A Tandem LC Workflow for Maximizing Mass Spectrometer

Today, tomorrow, and forever – PFAS, the “forever chemical”, have emerged as one of the greatest public health concerns of our time, infiltrating our environment and food supply. Herein, join us on Digital Classrooms for an in-depth exploration of PFAS, tracing their origins in everyday consumer products and examining their potential health implications.Our experts, Dr Yap Siew Qi and Elton Goh, will guide you through this critical topic, exploring the regulatory landscape with insights into EFSA and FDA guidelines. They will also introduce Shimadzu's innovative LC-MS/MS solutions, featuring the latest LCMS-TQ RX series. Discover how their robustness, sensitivity, and accuracy can enable effective detection of PFAS in complex food and environmental samples.Let’s work together to overcome global PFAS challenges. Register now to stay informed on this pressing issue!<h5>Learning Objectives:</h5><ul><li>Understand the implications of PFAS presence in food and environment &nbsp;</li><li>Navigate the evolving regulatory landscape for PFAS &nbsp;</li><li>Discover the capabilities of Shimadzu LCMS-TQ RX to detect PFAS in food and environmental samples</li></ul><blockquote>Presenter: Goh Wan Yu Elton (Market Specialist Food, Shimadzu (Asia Pacific) Pte Ltd)Elton is a dedicated and experienced Food Market Specialist at Shimadzu, bringing over nine years of expertise in food safety and analytical chemistry to his role. His career began at the Singapore Food Regulatory Board, where he spent seven years honing his skills and developing a profound understanding of regulatory standards and testing protocols. With a passion for knowledge and innovation, Elton transitioned to the private sector, contributing significantly to the advancement of analytical techniques and the development of novel food safety solutions during his two-year tenure at a research and development centre.Now at Shimadzu, Elton continues to excel, leveraging his expertise to develop cutting-edge analytical methods for detecting and quantifying various compounds in food products. His commitment to food science is evident in his efforts to enhance safety standards, build consumer trust, and make meaningful contributions to the global food industry.Presenter:&nbsp;Yap Siew Qi (LCMS Product Specialist, Shimadzu (Asia Pacific) Pte Ltd)Yap Siew Qi is an experienced professional in analytical chemistry, with a strong focus on liquid chromatography-mass spectrometry (LCMS). Her career commenced as a Research Assistant at the NUS Life Sciences Institute, where she acquired substantial experience in scientific research and laboratory techniques. This role was pivotal in developing her comprehensive understanding of life sciences, setting the stage for her future contributions to analytical chemistry and instrumentation.In 2022, her journey continued at Shimadzu (Asia Pacific), where she joined as an Application Chemist, focusing on LC/LCMS. In this capacity, she refined her expertise in LCMS technology, delivering prompt application support and technical solutions for the customers. Her exceptional skills and knowledge in LCMS soon led to her advancement to the position of Product Specialist. In this role, she continues to provide specialized knowledge and support, demonstrating her dedication to the progression of analytical chemistry and her proficiency in applying innovative technology within the field.Presenter:&nbsp;Mr. Ramaswamy Parthiban (Assistant Vice President, TUV SUD South Asia)Mr. R Parthiban has a robust background in operations management and quality assurance within the testing, inspection, and certification industry. He currently serves as AVP at TUV SUD South Asia, a position he has held since March 2022. Prior to this, he was the National Head at Prime Certification &amp; Inspection from April 2020 to June 2021. His experience also includes a significant role as Director of Operations at ALS Testing Services India Pvt Ltd from July 2018 to March 2020, where he led strategic initiatives and operational excellence.Earlier in his career, Mr. Parthiban held leadership roles including VP Operations at Merieux NutriSciences and Laboratory Manager for Chemistry at Exova Bahrain/KSA. His extensive experience in the industry is complemented by his earlier positions as Senior Manager at Coca-Cola and Laboratory Manager at SGS India Private Ltd. He began his career as a Research Associate at the John F. Welch Technology Center and ITC R&amp;D Center, eventually progressing to an Executive role in Quality Assurance at Sanmar Speciality Chemicals Ltd. Mr. Parthiban's career is marked by his expertise in quality systems, operational management, and strategic leadership in both national and international contexts.</blockquote>

Shimadzu: Discover The Latest LC-MS/MS Innovations For PFAS Challenges

Discover The Latest LC-MS/MS Innovations For PFAS Challenges

Discover how their robustness, sensitivity, and accuracy can enable effective detection of PFAS in complex food and environmental samples.

Understanding disease at a biological level requires deep, precise analysis. Multi-omics assays provide this depth, offering critical insights into human health and disease progression. However, these advanced methods come with challenges—especially when it comes to standardization and reproducibility.<h4>Join us for an informative webinar and panel discussion where we will:</h4><ul><li>Explore Quantitative Metabolomics: Discover how this powerful approach distinguishes health from disease and unlocks new insights into biological mechanisms.&nbsp;</li><li>Learn About Automated Sample Preparation: Get up to speed on the latest advancements in automated workflows, including the use of kit-based LC-MS/MS for reliable metabolomics profiling.Enhance Your Research Efficiency: Understand how integrating advanced technologies can streamline the verification and monitoring of potential biomarkers, leading to more cohesive analytical workflows.</li></ul><h4>Featured Presentations</h4><ul><li>Hear from experts at the University of Minnesota and University of Surrey as they showcase real-world applications and validations of these workflows. You'll gain exclusive insights from leaders in the field who are at the forefront of metabolomics research.</li></ul><h4>Key Learning Points</h4><ul><li>Unlock the Power of Quantitative Metabolomics: Learn how this approach helps differentiate health from disease and provides crucial insights into biological processes.</li><li>Streamline Your Research: Discover how comprehensive analytical workflows can speed up the verification and monitoring of lipid and small molecule biomarkers.</li><li>Dive into Advanced Automation: Explore cutting-edge sample preparation with the Waters™ Andrew+ automated liquid handler and the biocrates MxP® Quant 500 kit, transforming targeted metabolomics studies.</li><li>Master LC-MS/MS Workflows: Gain insights into the expanded biocrates MxP® Quant 500 XL, optimized for use with the Waters Xevo™ TQ Absolute MS, for robust lipidomics and metabolomics data.</li><li>Engage with Leading Experts: Take advantage of the opportunity to interact with experts from the University of Minnesota, University of Surrey, Waters Corporation, and Biocrates.</li></ul><blockquote>Presenter: Dr Holly-May Lewis (Senior Laboratory Technician, University of Surrey, UK)Dr. Holly-May Lewis is a Senior Laboratory Technician and specialist in Liquid Chromatography Mass Spectrometry (UPLC-MS/MS) at the University of Surrey's Chronobiology Section. With a PhD in Chemistry from the University of Surrey, she brings deep expertise in analytical chemistry to her current work, where she focuses on cutting-edge UPLC-MS/MS metabolomics of human samples.Presenter:&nbsp;Professor Debra Skene PhD (Professor of Neuroendocrinology, University of Surrey, UK)Debra J. Skene, PhD, FMedSci is a distinguished Professor of Neuroendocrinology in the Chronobiology Section at the University of Surrey, UK. With over 30 years of research experience and more than 200 peer-reviewed publications, her work focuses on the human circadian timing system and related sleep/wake disorders, particularly in blind individuals, shift workers, and older adults. Currently, her research explores the links between circadian clocks, sleep, and metabolism in both health and disease, utilizing advanced metabolomics techniquesPresenter:&nbsp;Dr Zachary J Mayer (Research Scientist at the Center for Metabolomics and Proteomics (CMSP), University of Minnesota)Dr Zachary Mayer is a Research Scientist at the Center for Metabolomics and Proteomics (CMSP) at the University of Minnesota, specializing in high-throughput targeted metabolomics by Liquid Chromatography Mass Spectrometry (LC-MS), sample preparation, and laboratory automation.</blockquote>

Waters Corporation: LC-MS/MS Workflows for Kit Based Quantitative Metabolic Profiling

LC-MS/MS Workflows for Kit Based Quantitative Metabolic Profiling

Multi-omics assays provide this depth, offering critical insights into human health and disease progression.

LC-MS/MS Workflows for Kit Based Quantitative Metabolic

The presence of per- and polyfluoroalkyl substances (PFAS) in food supply chains is a growing concern due to their environmental persistence and potential health risks.As awareness increases, the demand for effective regulations and advanced analytical methods for detecting PFAS in food is critical. In this webinar hosted by Agilent in association with AOAC India Section, we will explore the current PFAS contamination landscape, regulatory frameworks, and the latest analytical solutions.The session will cover PFAS characteristics and the challenges they present to food safety. We will examine global and regional regulations, with a focus on evolving standards in India and the South Asia Pacific region. Also, the webinar will highlight advanced analytical approaches for different food matrices like seafood, eggs, meat, infant formula, packaging material, including sample preparation, instrumentation, and reporting essential for effective PFAS detection. Agilent's robust LC/MS and GC/MS PFAS testing solutions will be showcased along with the Captiva EMR sample preparation kit, demonstrating how they can help food manufacturers, exporters, and regulatory bodies ensure compliance with global standards.<h4>Learning outcomes:</h4><ul><li>Comprehensive understanding of PFAS characteristics and the regulatory landscape across global and regional markets, including India and the South Asia Pacific.</li><li>Advanced analytical techniques for PFAS detection in food, covering sample preparation, instrumentation, and reporting methodologies.</li><li>Practical insights into implementing PFAS testing solutions to ensure compliance with international food safety standards.</li></ul><h4>Who should attend:</h4><ul><li>Food scientists, analytical chemists, regulatory authorities, government lab personnel, industry professionals in food manufacturing, packaging, exporting, R&amp;D scientists, toxicologists, QA/QC analysts and managers, academicians, and researchers focused on PFAS analysis and food safety.</li></ul><blockquote>Presenter: Dr. Nick Birse (Lecturer, School of Biological Sciences, Queen's University, Belfast, Northern Ireland, UK)Nick Birse is a Lecturer in Mass Spectrometry at Queen’s University Belfast, where he focuses on the use of mass spectrometry to solve key food integrity challenges, such as the measurement of chemical contaminants and natural toxins, fingerprinting foods to determine geographic origin and help detect fraud, or simply to measure key quality, flavour and taste attributes, all of which makes foods tastier, healthier and safer for consumers. Nick previously served as a Research Fellow within Prof Chris Elliott’s research group, assisting in the execution of Chris’s 2021 Agilent Thought Leader Award. He holds a PhD in Analytical Chemistry from Queen’s University Belfast.Presenter:&nbsp;Dr. Niladri Sekhar Chatterjee (Senior Scientist and DST Inspire Fellow, ICAR-Central Institute of Fisheries Technology, India)Dr. Niladri has more than 10 years of experience in precision measurement of small molecules in food, biological, and environmental matrices. His doctoral research is on pesticide metabolism, and environmental fate in crop, soil, and water. His postdoctoral research is on seafood authentication using high resolution mass spectrometry-based metabolomics and molecular spectroscopy fingerprinting. He currently works as a Senior Scientist in the Biochemistry and Nutrition Division at ICAR Central Institute of Fisheries in Kochi. At CIFT, he has been instrumental in establishing a state-of-the-art analytical chemistry laboratory from scratch which is today one of the National Reference Laboratories. He has received external grants from the Science and Engineering Research Board (SERB) India, National Agricultural Science Fund, and FSSAI. In the NRL, he has developed and validated precision measurement methods for multiclass analysis of pesticides, antibiotic residues, and endocrine disruptors and is actively managing the ISO 17025 accreditation of the laboratory. His research work has resulted in several peer reviewed publications.Presenter:&nbsp;Dr. Lorna De-Leoz (Global Food Segment Director, Agilent Technologies, USA)Lorna De Leoz has nearly 20 years of experience in the food industry. As the Global Food Segment Director, she collaborates with scientists to help develop accurate and reliable testing for food safety, quality, and authenticity. Lorna worked at the National Institute of Standards and Technology in the Mass Spectrometry Data Center for seven years. She completed her Ph.D. in Chemistry at University of California, Davis on milk oligosaccharides and glycan biomarkers analyses.</blockquote>

Agilent Technologies: PFAS in Food Supply Chains: Regulations and Analytical Approaches: in association with AOAC India Section

PFAS in Food Supply Chains: Regulations and Analytical Approaches: in association with AOAC India Section

PFAS characteristics and the challenges they present to food safety.

PFAS in Food Supply Chains: Regulations and Analytical

Nitrosamine Drug Substance-Related Impurities (NDSRI's) are a class of impurities that can form in drug substances and products. These impurities are of significant concern due to their potential carcinogenicity. Regulatory bodies, including the FDA, have established guidelines and acceptable intake limits to ensure the safety and efficacy of medications.NDSRI webinar series is a comprehensive three-part webinar series designed to provide valuable insights into the evolving landscape of analytical methods and regulatory requirements. This series will cover critical topics that are essential for professionals in the field.Key learnings:<ul><li>Understanding Nitrosamine / NDSRI and their impact on drug safety.</li><li>Latest regulatory guidelines and requirements.</li><li>Navigating Nitrosamines with Agilent 21 CFR compliant mass Hunter Software.</li><li>A focus on components in chromatographic challenges, with examples of NDSRI methods.</li><li>Case studies and real-world applications.</li><li>Column and consumable selection and how it influences the analysis.</li><li>Best practice for method optimization, development, and automation.</li><li>and more</li></ul><blockquote>Presenter: Dr. Kuldeep Sharma (Sales Development Manager - Pharma, Agilent Technologies)Kuldeep Sharma has over 19 years of experience in area/s of Bioanalytical research, Drug metabolism &amp; pharmacokinetics and Pharma regulatory compliance. He has accomplished PhD in Biotechnology. His professional journey covers over 12 years in Analytical research (associated with R&amp;D’s of Zydus Cadila, Lambda, Pliva and Jubilant Biosys) and last 7 years in analytical instruments sales, marketing &amp; business development. With over 21 research articles published in international Journals, He presents convention of continues learning.Presenter:&nbsp;Dr. Prasanth Joseph (Application Engineer - LC/MS, Agilent Technologies)Prasanth is an experienced analytical instrumentation professional with a specialization in small molecule applications. Joining Agilent in 2015 as an Application Engineer for LC-MS/MS, he has 19 years of expertise in the field. Prasanth holds a Ph.D. in Environmental Science from Bharathiar University, India, and a master's degree in Business Administration from the University of Buckingham, UK. His extensive knowledge includes developing analytical methods for quantifying genotoxic impurities, analyzing extractables and leachables in pharma and food packaging, conducting bioavailability and bioequivalence studies, and more. Prasanth's proficiency extends to the analysis of phytochemicals, food residue screening, and environmental sample contaminants.Presenter:&nbsp;Mr. Ankush Sharma (Regional Marketing Program Manager- APAC (Pharma &amp; Biopharma), Agilent Technologies)Ankush Sharma is a seasoned professional with over 12 years of extensive experience in sales and marketing across the pharmaceutical and biopharmaceutical sectors. His professional journey commenced with a strong educational foundation, earning a Master's degree in Biotechnology. Building upon this knowledge, he furthered his academic pursuits by obtaining a Master's in Business Administration with a specialization in Sales and Marketing, demonstrating his commitment to blending scientific understanding with strategic business acumen. For the past five years, he has been an integral part of Agilent, serving as the Regional Marketing Program Manager for the India and now Asia-Pacific (APAC) region for Pharma and Biopharma Markets.</blockquote>

Agilent: Nitrosamines & NDSRI's: Be sure with Agilent workflows

Nitrosamines & NDSRI's: Evolving Regulatory Landscape in Nitrosamines and NDSRI’s analysis.

NDSRI webinar series is designed to provide valuable insights into the evolving landscape of analytical methods and regulatory requirements.

Nitrosamines & NDSRI's: Be sure with Agilent workflows

<h4>The Waters 2024 Virtual Summer School - An Educational Journey to Master Food &amp; Environmental Analysis</h4>Unlock the full potential of LC-MS techniques with our immersive and educational sessions at the Waters Virtual F&amp;E Late Summer School 2024. From September 24th to 26th, engage with leading experts and discover cutting-edge methods for environmental and food analysis.<h5>Why attend?</h5><ul><li>Comprehensive Learning: Dive deep into advanced LC-MS techniques and gain practical knowledge to enhance your laboratory's analytical capabilities.</li><li>Expert Insights: Learn from industry leaders and gain firsthand experience through detailed modules on chromatography, mass spectrometry, and sample preparation.</li><li>Regulatory Compliance: Stay ahead with the latest insights on EU regulations for PFAS analysis in food and water, ensuring your lab meets stringent standards.</li></ul><h3>Episode #2: Tandem Quadrupole MS and MS-Method Development | F&amp;E Summer School - Day 1 - Module 2</h3>In this episode it’s all about the tandem quadrupole mass specs and the setup of MS-methods. We will demonstrate, using actual hardware, how simple it is to prevent contamination or clean a system, regardless of whether it’s at the low or high end of the sensitivity spectrum. You will learn valuable tips and tricks about UniSpray, a unique ion source and alternative to ESI.With our new waters_connect for Quantitation software, we will guide you through the different stages of MS-method development. You will learn how straightforward automated compound optimization can be, and how intuitively the new Method Acquisition Editor can be utilized by operators providing a clear structured all in one view of compounds and parameters. Search options make it easy to navigate through large multi-residue methods. And in the end, you are just one click away from the processing method that will be the topic of Episode 4.<h5>What you'll learn:</h5><ul><li>Easy operation and maintenance of Waters TQ-MS systems</li><li>Usage and benefits of UniSpray ion source</li><li>Step by step MS-method development with waters_connect for Quantitation</li></ul><blockquote>Presenter:&nbsp;Benjamin Wuyts, PhD (Senior Solution Support Specialist Europe, Waters Corporation)Benjamin initially joined Waters as an application chemist working in the Belgian demo lab, performing liquid chromatography-mass spectrometry demonstrations, support and training. In 2016 Benjamin became a European application chemist focusing on projects to support emerging applications. Benjamin has been focused over several years in establishing the Waters solution to the analysis of polar anionic pesticides, utilising novel column phases and LC-MS/MS technologies.</blockquote>

Waters Corporation: The Waters 2024 Virtual Summer School

Tandem Quadrupole MS and MS-Method Development

In this episode it’s all about the tandem quadrupole mass specs and the setup of MS-methods.

<h4>Overview</h4>We invite you to our 2nd Annual Virtual Biosymposium. This year, we will explore novel analytical characterization and quantitation of emerging modalities, such as DNA and mRNA, along with key method development considerations with global thought leaders.We look forward to seeing you! Key Event Objectives:<ul><li>Learn about novel approaches to characterizing established and modern biotherapeutic modalities</li><li>Understand key considerations when developing characterizing and quantitating methods for biomolecules</li><li>Take a deep dive into the values of fit-for-purpose methods to make critical drug decisions</li></ul>AGENDA7:30am AM (PT) - Welcoming Introductions<ul><li>Tran N. Pham, Global Biopharma Market Development Manager at Phenomenex</li></ul>7:35 AM (PT) - "Solutions &amp; Characterization Strategies for IVT mRNA Therapy Development"<ul><li>Charles Bai, Lead Application Scientist, VectorBuilder, Chicago, USA</li></ul>8:05 AM (PT) - &nbsp;"Utilizing Size Exclusion Chromatography for the Quality Control Analysis of Gene Therapeutics”<ul><li>Rebecca Hirschberger, QC Manager Bioanalytical Implementation, and Dr. Christopher Gawlig, QC Manager Research and development, Biospring, Germany</li></ul>8:35 AM (PT) "Impurity Profiling Optimization of GalNAc-conjugated Oligonucleotides by LC-MS-UV"<ul><li>Roxana Eggleston-Rangel, Senior Applications Scientist, Phenomenex, California, USA</li></ul>9:05 AM (PT) – Round Table Q&amp;A<ul><li>Tran N. Pham, Global Biopharma Market Development Manager at Phenomenex</li></ul>9:25 AM (PT) – Closing Remarks<blockquote>Presenter: Charles Bai (Lead Application Scientist)Charles has received his PhD in Microbiology at Purdue University. As a Lead Application Scientist at VectorBuilder, his main responsibilities are to provide technical consultation for clients regarding gene delivery using viral and non-viral vectors. Regarding the application of in vitro transcribed (IVT) RNA, Charles has been helping researchers with the design, production and encapsulation of IVT mRNA, circRNA or saRNA for therapy and vaccine development.Presenter: Rebecca Hirschberger (Quality Control Bioanalytical Method Development)Rebecca has been in the chromatography industry for over 2 years and has practical experience in the quality control of gene therapeutics. She has earnt a Masters in pharmaceutical science from Ludwig-Maximilians University, Munich, focused on instrumental analytics. Since Dezember 2022 she is a licensed Pharmacist in Germany. Rebecca Hirschberger joined BioSpring in August of 2021 and she serves as QC Manager Bioanalytical Implementation. Her area of responsibility includes: Various analyses of oligonucleotides, including (tandem) mass spectrometry via qToF, biochemical techniques, i.e. ELISA, enzymatic transformation of oligonucleotides for analytical and quality control purposes and the Separation of oligonucleotides by chromatographic methods.Presenter: Roxana Eggleston-Rangel (Senior Applications Scientist, Phenomenex)Roxana joined Phenomenex in 2018 as an Applications Scientist and is currently working with the applications team to produce analytical solutions for scientist in the biopharma industry. Roxana’s current work focuses on characterization of mRNA, sgRNA and siRNA. Prior to Phenomenex, Roxana worked for Caltech and the University of Southern California developing LM-CS workflows for the proteomics community. Roxana Eggleston-Rangel received her bachelor’s and master’s degree in Chemistry and Biochemistry from California State University, Los Angeles.</blockquote>

Phenomenex: 2nd Annual Virtual Biosymposium

2nd Annual Virtual Biosymposium

Explore novel analytical characterization and quantitation of emerging modalities, such as DNA and mRNA

LCMS webinars focusing on LC/MS - page 53