🎤Alex BrodyIn this episode of Concentrating on Chromatography, we sit down with Alex Brody, an organic chemist at Aqua America, to discuss the rigorous analytical methods required for regulated drinking water testing.Alex walks us through the multi-step PFAS detection process using EPA Method 537.1, including extraction, nitrogen blowdown concentration, and LC-MS analysis. He explains why sample preparation and quality control are critical for achieving trace-level detection—and why these methods can't be rushed or simplified, even with new technologies available.We also explore taste and odor investigations, disinfection byproducts, and volatile organic compounds, plus the surprising reality of why regulated labs move slowly when adopting new instrumentation. You'll learn about the quality control checkpoints, peer review processes, and the misconceptions surrounding analytical turnaround times in compliance labs.<h5>Topics Covered:</h5><ul><li>Role of organic chemistry in regulated drinking water labs</li><li>EPA compliance requirements and regulatory bodies (EPA, PA-DEP)</li><li>PFAS detection using Method 537.1 and LC-MS</li><li>The critical importance of nitrogen blowdown sample concentration</li><li>Taste and odor analysis: MIB, Geosmin, and unknown compound identification</li><li>Why regulated methods evolve slowly (validation timelines, approval processes)</li><li>Quality control procedures: calibration checks, matrix spikes, surrogate standards, internal standards</li><li>Automated sample preparation and lab efficiency</li><li>Future PFAS regulations and Method 533 expansion</li></ul><h5>Ideal For:</h5><ul><li>Analytical chemists and environmental lab professionals</li><li>Water utilities and compliance officers</li><li>Chromatography practitioners interested in regulated workflows</li><li>Anyone curious about how drinking water safety is ensured</li></ul><h2>Video Transcription</h2><h3>Ensuring Safe Drinking Water Through Advanced Analytical Chemistry</h3><h4>Insights from a Regulated Water Testing Laboratory</h4>Analytical laboratories responsible for regulated drinking water testing operate under strict compliance frameworks to ensure the delivery of safe and reliable water supplies. In this interview, Alex, an organic chemist at Aqua America, outlines the scope of analytical work conducted in a modern water quality laboratory. The team primarily focuses on the determination of taste- and odor-causing compounds, disinfection byproducts, volatile organic compounds (VOCs), and per- and polyfluoroalkyl substances (PFAS). These analyses rely heavily on GC-MS and LC-MS instrumentation, supported by rigorous maintenance programs to ensure continuous operational performance and data reliability.<h4>Regulatory Compliance and Quality Control in Drinking Water Analysis</h4>Operating as a regulated drinking water laboratory requires adherence to stringent requirements established by agencies such as the U.S. Environmental Protection Agency (EPA) and state-level regulatory bodies. Compliance is driven by extensive quality control protocols integrated into every analytical batch. Typical workflows include calibration verification, matrix spike recovery assessments, internal standard monitoring, and surrogate performance checks. Notably, analytical batches are often limited in sample number to accommodate a substantial proportion of quality control samples, reflecting the critical importance of data defensibility in regulatory reporting.One common misconception is the perceived speed at which results can be delivered. In reality, comprehensive sample preparation, including extraction procedures and validation steps, can extend turnaround times to a full working day or longer. Additionally, validated regulatory workflows impose limitations on the rapid adoption of new analytical technologies, as method modifications must undergo formal evaluation and approval before implementation.<h4>Analytical Strategies for Taste and Odor Investigations</h4>Taste and odor events represent a significant operational challenge for water utilities. Standard targeted methods are routinely applied for compounds such as 2-methylisoborneol (MIB) and geosmin, which are commonly associated with earthy or musty sensory characteristics. When targeted analysis does not reveal the source, laboratories employ broad-scan GC-MS screening combined with spectral library interpretation to identify potential causative compounds. In some cases, sensory evaluation panels complement instrumental analysis, providing preliminary insight into potential treatment-related or environmental influences affecting water quality.<h4>PFAS Monitoring: Methodological Complexity and Trace-Level Sensitivity</h4>PFAS determination represents a rapidly evolving priority in drinking water monitoring. The laboratory currently applies EPA Method 537.1, with efforts underway to expand capabilities through certification for Method 533, thereby broadening analyte coverage. Analytical workflows typically involve solid-phase extraction followed by solvent evaporation using nitrogen-assisted blow-down techniques to achieve the trace-level sensitivity required for regulatory compliance. This concentration step is essential because PFAS compounds remain non-volatile under controlled evaporation conditions, enabling enhanced detection performance upon reconstitution and LC-MS analysis.<h4>Future Directions in Drinking Water Analytics</h4>Looking ahead, the primary technological driver in regulated water analysis is the demand for increasingly lower detection limits and expanded compound coverage. While regulatory frameworks can slow methodological innovation, laboratories continue to pursue efficiency improvements, such as automated sample preparation systems and optimized analytical workflows. These advances support the growing need to process high sample volumes while maintaining the stringent data quality standards required for public health protection.Ultimately, the work performed in regulated drinking water laboratories represents a critical intersection of analytical chemistry, environmental monitoring, and public safety. Continuous methodological refinement, coupled with advances in mass spectrometry and sample preparation technologies, will play a central role in addressing emerging contaminants and ensuring long-term water quality assurance.<blockquote>This text has been automatically transcribed from a video presentation using AI technology. It may contain inaccuracies and is not guaranteed to be 100% correct.</blockquote><blockquote><h4>Concentrating on Chromatography Podcast</h4>Dive into the frontiers of chromatography, mass spectrometry, and sample preparation with host David Oliva. Each episode features candid conversations with leading researchers, industry innovators, and passionate scientists who are shaping the future of analytical chemistry. From decoding PFAS detection challenges to exploring the latest in AI-assisted liquid chromatography, this show uncovers practical workflows, sustainability breakthroughs, and the real-world impact of separation science. Whether you’re a chromatographer, lab professional, or researcher you'll discover inspiring content!You can find Concentrating on Chromatography Podcast in podcast apps:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://open.spotify.com/show/1wZg67rCjoGju4yhqxI3tL">Spotify</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podcasts.apple.com/tz/podcast/concentrating-on-chromatography/id1788429185">Apple podcast</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podscan.fm/podcasts/concentrating-on-chromatography">podscan</a></li></ul>and on <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/@ChromatographyTalk/videos">YouTube channel</a></blockquote>

Regulated Drinking Water Testing: PFAS Detection, Sample Prep & Real Lab Insights

This study investigates how ionization polarity influences the gas-phase stability of native-like proteins analyzed by ion mobility spectrometry–mass spectrometry. While proteins generally retain folded structures in both positive and negative electrospray ionization modes, significant differences in unfolding behavior were observed.Proteins exhibited greater gas-phase stability when analyzed in the ionization polarity corresponding to their solution-phase charge, requiring higher energy for unfolding. These findings emphasize the importance of considering protein isoelectric points and ionization polarity in native IMS-MS experiments to ensure accurate structural characterization.<blockquote><h4>The original article</h4><h4><a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acs.analchem.5c04295">Investigating the Effect of Isoelectric Points on the Gas-Phase Stability of Native-like Proteins Analyzed in Positive- versus Negative-Ion Mode by IMS-MS</a></h4>Alexis N. Edwards, Madeline G. Bannon, Michael S. Cordes, and Elyssia S. Gallagher*Anal. Chem. 2026, 98, 6, 4518–4527<a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1021/acs.analchem.5c04295">https://doi.org/10.1021/acs.analchem.5c04295</a><h6>licensed under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/">CC-BY 4.0</a></h6></blockquote>Selected sections from the article follow. Formats and hyperlinks were adapted from the original.<div>In native mass spectrometry (nMS), the native-like structures of proteins are maintained in the gas phase by preserving the secondary, tertiary, and quaternary structures. <a href="javascript:void(0);">(1−7)</a> The preservation of native-like protein structures is primarily accomplished via the use of electrospray ionization (ESI), a soft ionization method that forms a distribution of multiply charged protein ions. These multiply charged ions can then be investigated to characterize stoichiometry, oligomeric composition, and ligand binding. <a href="javascript:void(0);">(8−10)</a>During ESI, a potential is applied to the sample-containing solution. In an aqueous spray solvent, H3O+ and OH– are produced in positive-ion mode (+ESI) and negative-ion mode (−ESI), respectively. <a href="javascript:void(0);">(11)</a> The buildup of like-charges within the solution results in the formation of a Taylor Cone at the capillary tip, which ejects charged droplets that travel toward the inlet of the mass spectrometer. Droplets undergo evaporation and fission until complete analyte desolvation, leading to the release of folded, gas-phase protein ions. As the droplets shrink, H3O+ or OH– can become concentrated, causing the pH of the droplet to decrease or increase, respectively. Shifts in pH can denature proteins. Therefore, to maintain native-like protein structures, nMS is conducted with solutions containing volatile salts, usually ammonium acetate, that provide ionic strength and minimize pH changes compared to spraying from pure water. <a href="javascript:void(0);">(11,12)</a> Droplet pH in ESI is influenced by flow rate, solvent composition, and applied voltage, <a href="javascript:void(0);">(13)</a> but often approaches values near the pKa of acetate (4.76) or ammonium (9.25) in +ESI or −ESI, <a href="javascript:void(0);">(12,14)</a> respectively. During ESI, changes in overall protein charge take place via proton transfer at chargeable amino acid residues, resulting in the formation of protonated or deprotonated protein ions with the charged sites being dependent on the relative proton affinities of ammonium, acetate, and chargeable amino acids as proteins near complete desolvation. <a href="javascript:void(0);">(15−19)</a>Ion mobility spectrometry (IMS) measures an ion’s mobility through an inert gas under the influence of an electric field. Thus, mobility is directly influenced by the ion’s size, shape, and charge. <a href="javascript:void(0);">(20)</a> A protein’s mobility can be used to estimate its structure by calculating an average momentum-transfer collisional cross section (CCS). In addition to structural characterization, IMS-MS can investigate the gas-phase stability of protein complexes when paired with collision-induced unfolding (CIU). Specifically, in CIU experiments, protein ions are accelerated into a cell filled with inert gas molecules and undergo multiple collisions with higher frequency and energy relative to IMS. This converts kinetic energy to internal, vibrational energy, disrupting noncovalent interactions and inducing unfolding of the protein ions. <a href="javascript:void(0);">(21)</a> Unfolding alters the protein structure, which can then be quantified by monitoring the protein’s mobility during subsequent IMS-MS measurement. <a href="javascript:void(0);">(22)</a> Prior work with mutant proteins has shown that proteins with similar intramolecular interactions have similar CIU fingerprints, while proteins with different intramolecular interactions have different CIU fingerprints. <a href="javascript:void(0);">(23)</a> Therefore, gas-phase protein stability is correlated with intramolecular interactions.Past native IMS-MS work has primarily been conducted in +ESI given that -ESI has the reputation of being unreliable for native-like protein analysis due to the occurrence of corona discharge, <a href="javascript:void(0);">(24)</a> and charge-state distributions that may not be representative of folded proteins. <a href="javascript:void(0);">(25)</a> In recent years, −ESI has been increasingly used in CIU and IMS-MS, with recent work demonstrating that −ESI-MS is capable of discerning denatured and native-like protein structures. <a href="javascript:void(0);">(26,27)</a> Prior work showed that charge manipulation of folded proteins, such as charge reduction, to achieve similar absolute charge states in both ion modes, results in CCS values of protein cations that are comparable to their anion counterparts. <a href="javascript:void(0);">(26,28)</a> This suggests that gas-phase structures are weakly dependent on protein charge and ionization polarity. <a href="javascript:void(0);">(23,26,28)</a> Yet, Hong et al. showed that, in the absence of charge reduction, the gas-phase stability of two proteins (avidin and β-lactoglobulin) is sensitive to ionization polarity, highlighting that gas-phase stability is not consistent between +ESI and −ESI. <a href="javascript:void(0);">(29)</a><h4>Materials and Methods</h4><h5>Native IMS-MS Analysis</h5>Glass capillaries were pulled using a P-1000 micropipette puller (Sutter Instrument Company, Novato, CA). Samples and calibrants were sprayed from pulled capillaries (inner diameter ∼1 μm) and analyzed with a <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/152">Synapt G2-S High-Definition MS </a>(Waters Corporation, Milford, MA). The trap and transfer cells contained Ar, the helium cell contained He, and the IMS cell contained N2. IMS wave velocity was 350 m/s, while IMS wave height was either 7 or 9 V, depending on the protein size (see <a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/suppl/10.1021/acs.analchem.5c04295/suppl_file/ac5c04295_si_001.pdf">Table S2</a>). Proteins with larger mass required a wave height of 9 V to ensure that all the ions migrated out of the IMS cell prior to the next ion injection. Mass spectra were collected and signal averaged over 30 s. Additional instrument details can be found in the Supporting Information (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/suppl/10.1021/acs.analchem.5c04295/suppl_file/ac5c04295_si_001.pdf">Table S2</a>).To limit systematic error due to repositioning of the ESI tip between runs, <a href="javascript:void(0);">(48)</a> the XYZ-stage position was optimized and kept consistent for all replicates. Approximately 5 μL of sample was loaded into a glass capillary, which was then mounted on the XYZ-stage. Electric potential was delivered to the sample by a platinum wire inserted into the capillary and placed in contact with the solution. The voltage applied to the tip holder ranged from 0.60 to 1.2 kV for native samples, and 0.80 to 1.40 kV for denatured samples. Nine replicates in each ion mode were collected for all proteins with measurements spread across 8 days over 3 weeks. These replicates were conducted in pairs by collecting data in both ion modes consecutively. To accomplish this, a CIU experiment was collected in +ESI before the instrument polarity was changed to −ESI. A second CIU experiment was performed, beginning with −ESI to counteract any changes in protein stability due to pH changes during ESI. <a href="javascript:void(0);">(14)</a> This allowed for use of the same capillary, at the same position in relation to the instrument inlet, for each +ESI/–ESI replicate pair. A new tip was used for each +ESI/–ESI replicate pair. CIU experiments were accomplished by increasing collision voltage (CV) to the trap cell in 5 V steps, from 0 V to a maximum of 120 V.<h4>Results and Discussion</h4>Ten proteins were chosen for analysis in +ESI and −ESI in this work (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acs.analchem.5c04295#tbl1">Table 1</a>). These proteins can be broken into three groups depending on the net-charge in solution at pH 7: net-negative (with pI &lt; 6.5), net-neutral (with 6.5 ≤ pI ≤ 7.5), and net-positive (with pI &gt; 7.5). Five of the ten proteins have a net-negative charge at pH 7, though four of these proteins (con A, β-lactoglobulin, ovalbumin, and α-lactalbumin) are routinely analyzed via +ESI-IMS-MS. <a href="javascript:void(0);">(18,28)</a> Additionally, each protein had charge-state distributions in +ESI and −ESI that resulted in at least one overlapping charge state (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acs.analchem.5c04295#fig1">Figure 1</a>), allowing for direct comparison of TWCCSN2→He and CIU50 in both ion modes.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Anal_Chem_2026_98_6_4518_4527_Figure_1_Representative_mass_spectra_in_ESI_top_and_ESI_bottom_cb81976247.jpg" alt="Anal. Chem. 2026, 98, 6, 4518–4527: Figure 1. Representative mass spectra in +ESI (top) and −ESI (bottom) for (A) ovalbumin, (B) GNA, (C) β-lactoglobulin, (D) α-lactalbumin, (E) con A, (F) streptavidin, (G) ubiquitin, (H) WGA, (I) cytochrome c, and (J) lysozyme. Proteins that have blue or red charge states indicate additional oligomeric states that were detected. Outlines in red boxes are overlapping charge states that are compared herein. *Indicates contaminant peaks." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Anal_Chem_2026_98_6_4518_4527_Figure_1_Representative_mass_spectra_in_ESI_top_and_ESI_bottom_cb81976247.jpg 245w," sizes="100vw" width="1600" height="865"><h5>Proteins with Disulfide Bridges are Stable in Both Polarities</h5>For both lysozyme and α-lactalbumin, the average TWCCSN2→He were within experimental uncertainty in +ESI and −ESI for both the initial, folded structures and the final, extended structures (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acs.analchem.5c04295#tbl2">Table 2</a>). However, the 6+ and 6- ions of lysozyme and α-lactalbumin showed a high resistance to unfolding with &gt;90% of the ions retaining their folded TWCCSN2→He values even at high CV (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acs.analchem.5c04295#fig2">Figure 2</a>). Replicate data showed similar trends (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/suppl/10.1021/acs.analchem.5c04295/suppl_file/ac5c04295_si_001.pdf">Figure S2</a>). While CCS values provide a description of gas-phase structures, CIU experiments provide information on the stability of the gas-phase protein structures. Furthermore, the number and pattern of disulfide bridges present in antibodies has been characterized by CIU. <a href="javascript:void(0);">(63)</a> Lysozyme and α-lactalbumin both contain the glycosyl hydrolases family 22 (GH22) domain, which has four disulfide bridges that span ∼94% and ∼93% of the amino acid sequence, respectively (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/suppl/10.1021/acs.analchem.5c04295/suppl_file/ac5c04295_si_001.pdf">Figure S3</a>). Thus, we hypothesize that rather than effects from protein pI and ionization polarity, the unfolding behavior of these proteins is controlled to a greater extent by the presence of stabilizing disulfide bridges that prevent routine unfolding during collisional activation.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Anal_Chem_2026_98_6_4518_4527_Figure_2_Representative_mobiligrams_showing_arrival_times_for_lysozyme_A_C_and_a_lactalbumin_B_D_0f3d23c3c1.jpg" alt="Anal. Chem. 2026, 98, 6, 4518–4527 - Figure 2. Representative mobiligrams showing arrival times for lysozyme (A, C) and α-lactalbumin (B, D) at low and high CV (blue solid and orange dashed lines, respectively) for +ESI (A, B) and −ESI (C, D). For lysozyme, different values were chosen for the high CV (e.g., 540 eV in +ESI and 480 eV in −ESI) because these were the last analyzed CV where the signal-to-noise ratio (S/N) for the 6 ± ions was greater than 3." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Anal_Chem_2026_98_6_4518_4527_Figure_2_Representative_mobiligrams_showing_arrival_times_for_lysozyme_A_C_and_a_lactalbumin_B_D_0f3d23c3c1.jpg 212w," sizes="100vw" width="1600" height="1178">To characterize the stabilizing effect of disulfides, MD simulations were conducted that heat denatured 6+ ions of lysozyme and α-lactalbumin with disulfide bridges either present or removed with the resulting cysteine residues being protonated prior to heating (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/suppl/10.1021/acs.analchem.5c04295/suppl_file/ac5c04295_si_001.pdf">Figure S4</a>). Structural changes associated with heat denaturation were characterized by taking the root-mean-square deviation (RMSD) of the heated structures relative to initial, crystal structures. Over ten trials, lysozyme ions possessed an average RMSD of (1.6 ± 0.2) nm when disulfides were present which increased to (3.5 ± 0.5) nm when disulfides were removed. Similarly, the RMSD of α-lactalbumin ions increased from (1.8 ± 0.1) nm when disulfides were present to (3.7 ± 0.3) nm when disulfides were removed, suggesting that the disulfides serve as a barrier to unfolding. This is visually represented in <a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/suppl/10.1021/acs.analchem.5c04295/suppl_file/ac5c04295_si_001.pdf">Figure S4C,D</a> where simulated structures of heated lysozyme and α-lactalbumin ions with intact disulfides adopt more condensed configurations relative to those with disulfides removed. In essence, the disulfides “tie” disparate regions of protein together, which serves as a barrier to more thorough unfolding even at a maximum simulated temperature of 900 K, explaining the similarity of TWCCSN2→He values in +ESI versus −ESI as well as the limited percentage of ions that undergo a change in TWCCSN2→He upon additional collisional activation.WGA has 16 disulfide bridges per monomeric subunit (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acs.analchem.5c04295#tbl1">Table 1</a>). On average, these disulfides encompass seven amino acids each, with ∼78% the total amino acids in WGA being encompassed by at least one disulfide bridge (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/suppl/10.1021/acs.analchem.5c04295/suppl_file/ac5c04295_si_001.pdf">Figure S3</a>). Compared to lysozyme and α-lactalbumin, the presence of disulfide bridges across small numbers of amino acids enables WGA to unfold with ΔCCS of (370 ± 60) Å2 and (390 ± 120) Å2 in +ESI and −ESI, respectively (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acs.analchem.5c04295#tbl2">Table 2</a>). However, in comparison to the other lectins, GNA and con A, we hypothesize that these disulfide bridges in WGA limit the extent of unfolding, resulting in the extended, TWCCSN2→He values being within experimental uncertainty in both ion modes.To summarize, lysozyme and α-lactalbumin exhibit similar gas-phase behavior in both +ESI and −ESI, with most ions retaining folded structures even under high CV. We hypothesize this resistance to unfolding is largely attributed to their four disulfide bridges, which span over 90% of their sequences and act as stabilizing constraints. MD simulations confirm that removing these disulfides significantly increases structural deviation during heat denaturation, indicating their critical role in maintaining compact configurations. Consequently, the presence of disulfide bridges explains the minimal changes in TWCCSN2→He and the proteins’ high stability under activation.<h4>Conclusions</h4>IMS-MS allows for detailed analysis of the structure and stability of native-like proteins in the gas phase. The structure of a protein is dictated by its amino acid sequence and the resulting noncovalent interactions that form the secondary, tertiary, and quaternary structures. Chargeable amino acid residues that are solvent exposed can carry charges leading to the protein having a net-positive, net-negative, or net-neutral charge in solution at physiological pH. Yet, most native IMS-MS analysis is conducted in +ESI, leading to proteins that are net-negative in solution experiencing large swings in their net-charge during the ESI process.This work highlights that gas-phase stability of native-like proteins varies with ionization polarity. While CCS values for folded structures are generally comparable between +ESI and −ESI, unfolding energetics differ─net-negative proteins are more stable in −ESI, whereas net-positive proteins are more stable in +ESI. We hypothesize that these differences are due to changes in the intramolecular interactions within cationic and anionic proteins. Therefore, proteins analyzed in the mode opposite to their solution-phase charge may have different gas-phase structures compared to biological systems. For example, proteins that are net-negatively charged in physiological environments (pI &lt; 6.5) are more likely to represent their biological counterparts as gas-phase anions when analyzed in −ESI compared to +ESI, enabling nMS experiments to more closely characterize the structures present in biological systems.</div>

Investigating the Effect of Isoelectric Points on the Gas-Phase Stability of Native-like Proteins Analyzed in Positive- versus Negative-Ion Mode by IMS-MS

In the week of March 30, the following webinars await you in the field of liquid phase and especially HPLC and LC/MS.<blockquote><h4><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinars">👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</a></h4>👉 Search and filter in the largest global database with over 5 500 GC, LC, MS and spectroscopy webinars.</blockquote><h5>1. Bruker: MALDI Imaging Becomes IR-resistible: Going Multimodal for Advanced Biomedical Insights</h5><ul><li>Mo, 30.3.2026 16:00 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/5971">Registration</a></li></ul>Explore advanced multimodal imaging with MALDI, QCL-based IR, and fluorescence microscopy to achieve ROI-focused molecular insights in complex tissues.<h5>2. Shimadzu Corporation: Environmental PFAS Testing: Introducing Next-Generation Mass Spectrometry Solutions</h5><ul><li>Tu, 31.3.2026 09:30 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/6026">Registration</a></li></ul>Explore advanced PFAS analysis strategies combining LC-MS/MS and MALDI-TOF screening to improve sensitivity, efficiency, and regulatory readiness in environmental testing.<h5>3. Tosoh Bioscience: Tosoh Tuesday - Scaling Up from Process Development to GMP Production with Pre-packed Columns</h5><ul><li>Tu, 31.3.2026 15:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/6089">Registration</a></li></ul>This webinar will introduce SkillPak™ MAX pre-packed columns and present performance data using TOYOPEARL® Super A, a novel Protein A resin.<h5>4. Phenomenex: Recipe for Separation: Crafting Your Perfect HPLC Method</h5><ul><li>We, 1.4.2026 10:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/6091">Registration</a></li></ul>Discover how to properly use and maintain your column to maximize its performance and lifespan.

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Join us on Thursday, May 15th Online or in Freising (Germany) to share your knowledge and challenges with peers and E&amp;L experts. This edition’s focus will be Consumer Safety vs Environmental Protection – FCM and E&amp;L.The workshop will be hybrid and visiting Germany, so you can alternatively:<ul><li>Attend online via Zoom</li><li>Join us at Fraunhofer Institute in Freising (Germany)</li></ul><h4>Registration information:</h4><ul><li>Online event registration: via <a target="_blank" rel="noopener noreferrer" href="https://waters.zoom.us/webinar/register/7417371130225/WN_jvzK46CzShOB62ECZ4Dt1A#/registration">Zoom</a></li><li>In-person event registration: If you wish to join us in Freising (Germany) to attend the in-person event, please fill the following <a target="_blank" rel="noopener noreferrer" href="https://web.cvent.com/event/377111a9-b0e3-4225-b2fc-195fe1e255ae/regProcessStep1">registration form</a></li></ul><h4>This years TOPICS:</h4><ul><li>Latest Developments in Analytical Instrumentation Solutions.</li><li>Analytical consequences for recyclers and food packaging producers of the EU Regulation 2022/1616 on recycled plastic materials and articles intended to come into contact with foods and its practicalities</li><li>PFAS as a NIAS – the Analytical Challenges</li><li>BPA, BPS and other Endocrine Liabilities</li></ul>Speakers will be Subject Matter Experts from Public Labs, Contract Labs, Legislators, Technical Experts, Producers and Recycling researchers.<h4>Agenda</h4>In-person event program will be enriched by afternoon small groups focus discussion and lab sessions: you will have additional chance to:<ul><li>Meet the experts on FCM, E&amp;L and recycling processes</li><li>Share knowledge and challenges with Peers and E&amp;L Experts</li><li>Expand your Network</li></ul><h4>Please note that:</h4><ul><li>The Workshop is free of charge and will be delivered in English</li></ul>We are looking forward to meeting you in Freising or online!

Waters Corporation: 8th Annual Swiss BASF and Waters Workshop on Extractables and Leachables/Food Contact Materials

8th Annual Swiss BASF and Waters Workshop on Extractables and Leachables/Food Contact Materials

Join Waters AG and BASF Schweiz AG have the pleasure to invite you to the Annual Swiss Networking Workshop on Extractables and Leachables/Food Contact Materials

BASF and Waters Workshop on Extractables and Leachables

<div><div>Let's go back to the Basics of Chromatography, Mass Spectrometry, Data Analysis and Trouble-shooting: understanding the importance of the basics will enable you to be more effective in your daily laboratory life.This journey started in 2024 and we are now pleased to invite you to join us to go deeper in fundamentals, troubleshooting and application specific topics.<h3>EPISODE 4: Fit for Purpose Analysis: How to Combine the Separation with the Correct LC and Detection Technique</h3>What will you learn?<ul><li>Choose the Correct LC Gradient System for Your Challenging Separations</li><li>Select the Suitable (Combination of) Detectors required for Sensitivity, Specificity and Linearity</li></ul>What's next?<ul><li>Check out the full Webinar Series Episodes List <a target="_blank" rel="noopener noreferrer" href="https://event.on24.com/eventRegistration/EventLobbyServlet?target=reg20.jsp&amp;eventid=4817889&amp;sessionid=1&amp;key=B9182AE813B3F8A30217606156F96B75&amp;groupId=5901784&amp;sourcepage=register">here</a></li></ul>Not sure to be able to attend live sessions?&nbsp;<ul><li>Register today and watch the webinars on-demand</li></ul><blockquote>Presenter: Antonia Wierzbicki (Principal MS Market Dev Manager, EMEA, Waters Corporation)Antonia Wierzbicki is a MS market development manager at Waters working in EMEA. Antonia has BSc in Pharmaceutical Science and a MSc in Cancer Pharmacology. Following several years working as an analytical chemist in drug development roles within both academic labs and contract research organizations, Antonia has more recently spent time working with analytical chemists to provide solutions using cutting edge technologies to meet their needs and requirements, with a specific interest in ultra-sensitive quantitation of small molecules. Antonia is based in Cambridge UK and keen to connectwith like-minded scientists in the field.Presenter: Andrea Gheduzzi (Principal LC Market Dev. Manager, EMEA, Waters Corporation)Andrea Gheduzzi, is a principal LC market development manager for EMEA at Waters Corporation. Andrea Gheduzzi has spent more than 30 years in the chromatography field. Across his career he had various roles, service engineer, chromatography lab manager position, and technical manager for chromatography columns. He has mainly been dealing with pharma accounts, also supporting LC method development activities using DoE/QbD approaches. In his previous role as Pharma Business Development Manager at Waters he has further expanded his expertise in AQbD and related applications. Since 2023 he became principal LC market development manager for EMEA and member of the AQbD working party at the EDQM.Presenter: Arjan Timmerman (Pharma Market Development Manager EMEA, Waters Corporation)Arjan Timmerman is a market development manager at Waters working in EMEA. Prior to joining Waters in 2014 he worked for 17 years as an Analytical Scientist in the Small Molecule Pharmaceutical industry in various Chemical and Pharmaceutical late-stage development labs. Since 2023 he became QA/QC market development manager for EMEA working in a dedicated team and focuses on Pharmaceutical workflows, AQbD, Impurities, LC Chromatography and Compliance.</blockquote></div></div>

Waters Corporation: Back to Basics Advanced Webinar Series 2025

Back to Basics Advanced - Pharma Impurities: Detection (UV/MS) 

Choose the Correct LC Gradient System for Your Separations. Select the Suitable (Combination of) Detectors required for Sensitivity, Specificity and Linearity.

Pharma Impurities: Detection (UV/MS) 

This live webinar delves into the detection of antibiotics, including Anthelmintics, Aminoglycosides, Cephalosporins, and Beta-lactams, as well as mycotoxins in dairy products using LC/MS/MS solutions aligned with EIC and FSSAI standards.Participants will gain insights into regulatory implications and supply chain challenges in managing these contaminants.The session will also highlight practical workflows for laboratories and manufacturers to meet stringent safety and compliance requirements.<blockquote>Presenter: Mr. Praveen Bhambi (Executive Director, Mehsana DCMPUL., India)He is a Dairy Technologist from Sheth M.C. College of Dairy Science (AAU, Anand, 1986) and holds a Post Graduate Diploma in Rural Management from IRMA. With 39 years of diverse experience in the dairy sector, he has expertise in milk procurement, production, processing, sales, marketing, project management, and IT system implementation, including Oracle 11i and SAP. He has independently managed several large-scale projects, such as a state-of-the-art dairy plant in Manesar with a capacity of 10 LLPD milk processing, 50,000 liters of ice cream, and 50 MT of dahi production.Currently, he oversees operations at Dudhsagar Dairy (Mehsana), Dudhmansagar Dairy (Manesar), Dudhmotisagar Dairy (Dharuhera), and various other units outside Gujarat, along with spearheading new projects like a 120 TPD powder plant and a 3 LLPD UHT plant with a project outlay of ₹500 crores. Shri Bhambi also attended the Quality Management Program in Yokohama, Japan, in 1998.Presenter:&nbsp;Dr. Rajiv Chawla (Senior Scientist, NDDB - CALF Ltd., India)Rajiv Chawla holds a Master’s and Doctorate in Animal Nutrition from the National Dairy Research Institute (NDRI), Karnal. After completing his studies in 2001, he began his career as a chemist in a food testing laboratory and joined the CALF Laboratory of the National Dairy Development Board (NDDB) in 2008.With over 20 years of experience in the analytical field, he specializes in compositional and nutritional analysis as well as contaminants testing, including pesticides, mycotoxins, and antibiotics. He has been an integral part of the team responsible for establishing advanced technologies at NDDB’s laboratory, such as dioxin and furan analysis, triglyceride-based milk fat adulteration tests, and honey authenticity testing. In addition to testing, his expertise includes method validation and the implementation of ISO 17025 standards. He is an active member of the BIS and IDF committees.Presenter:&nbsp;Dr. Prasanth Joseph (Application Engineer - LC/MS, Agilent Technologies India Pvt. Ltd.)Dr. Prasanth is a seasoned professional in analytical instrumentation, specializing in small molecule applications. With 19 years of experience, he joined Agilent in 2015 as an Application Engineer for LC-MS/MS. He holds a Ph.D. in Environmental Science from Bharathiar University, India, and a master’s degree in business administration from the University of Buckingham, UK. Prasanth has extensive expertise in developing analytical methods for genotoxic impurities, extractables and leachables in pharma and food packaging, and conducting bioavailability and bioequivalence studies. His sk ills also include the analysis of phytochemicals, food residue screening, and contaminants in environmental samples.Presenter:&nbsp;Dr. Ramaprasad Ganni (Technical Support Specialist, Agilent Technologies India Pvt. Ltd.)Dr. Ramprasad has 21 years of experience in the field of Chromatography and Column chemistries. Worked for Elsevier GmbH; Germany, and Millipore India Pvt, Ltd. Presently working with Agilent technologies; India, since 2008 in Chemistries and Supplies division. Responsible for Workflow solutions development, providing technical support, and trainings for various industries of Food, Pharma, Petroleum, Bio-technology. Experienced in developing applications, LC and GC column chemistries and technologies, Sample preparation techniques, method developments and troubleshooting the problems of various chromatography technologies such as LC, GC, Mass Spectrometry, GPC/SEC, and Preparative LC.</blockquote>

Agilent Technologies: Antibiotics and mycotoxins testing

Antibiotics and mycotoxins testing

This webinar delves into detection of antibiotics, including Anthelmintics, Aminoglycosides, Cephalosporins, and Beta-lactams, in dairy products

<div>Light scattering techniques like MALS and DLS offer critical insights into biotherapeutic development by enabling the assessment of absolute molar mass, aggregation, colloidal stability, and structural modifications.This webinar will provide an introduction to SEC-MALS and DLS, highlighting their applications for characterizing monoclonal antibodies (mAbs), conjugated proteins, and adeno-associated viruses (AAVs). Learn how cutting-edge instrumentation delivers absolute molecular weight, size, and composition measurements for biotherapeutics.<h4>Key Learning Objectives:</h4><ul><li>Fundamentals of Multi-Angle and Dynamic Light Scattering</li><li>Application of advanced light scattering techniques (DLS, SEC-MALS) for biopharmaceutical characterization</li><li>Understanding the limitations of SEC/GPC and how does MALS and DLS address these challenges</li></ul><h4>Who Should Attend:</h4><ul><li>Researchers interested in learning more about light scattering</li><li>Any scientist working in the development or quality control space</li><li>Researchers with chromatography systems that need accurate and precise molar mass and size distribution results</li></ul><blockquote>Presenter: Udayabagya (Bud) Halim (Sr. Marketing Analyst)Bud Halim is a Senior Marketing Analyst at Wyatt Technology, bringing a wealth of scientific expertise to the analytical instrumentation field. He earned both his B.S. and Ph.D. in Physical Chemistry from UCLA, where his passion for science began. Bud started his career in academia as an adjunct professor, teaching Biochemistry, Analytical Chemistry, and Physical Chemistry, while also contributing as an editor and author to several laboratory manuals. He later transitioned into the scientific instrumentation industry, serving in roles including applications scientist, with hands-on experience in the characterization of batteries, semiconductors, and the stability of biologics, including LNPs and viral vectors.</blockquote></div>

Waters Corporation: Introduction to Multi-Angle and Dynamic Light Scattering: Applications in Biotherapeutics

Introduction to Multi-Angle and Dynamic Light Scattering: Applications in Biotherapeutics

This webinar will provide an introduction to SEC-MALS and DLS

Intro to MALS & DLS: Biotherapeutic Applications

Join François Espourteille on Tuesday, May 13, for our workshop "Rapid DART-MS Screen for Benzodiazepines in Urine Enabled by DART (Direct Analysis in Real Time) Technology" and discover the power of DART-MS in providing selective results, reducing false positives and negatives, and enabling rapid addition of new target analytes.Learn about our chromatography-free screening approach for benzodiazepines and their metabolites in urine, including alprazolam, clonazepam, diazepam, and more. This method measures 14 analytes in 96 samples with a throughput of 23 seconds per sample.<h5>Learning Objectives:</h5><ul><li>Understand the principles of DART-MS and its advantages over IA-based screening.</li><li>Learn the rapid, chromatography-free screening method for benzodiazepines.</li><li>Gain insights into sample preparation and analysis using EVOQ DART-TQ+ mass spectrometer.</li></ul>And don't miss the chance to hear Jeff Zonderman speak on the benefits and new developements of chromatogrphy-free workflows and join his talk “Bruker, Bringing Chrom-Free To The Masses” on Tuesday, May 13, at 10 am ET.The workshop and talk are part of the 2025 Online Symposium on Current Trends in Forensic Toxicology by the CFSRE. The symposium, themed “Innovating for a Smarter, Sustainable, and Efficient Future in Forensic Toxicology,” will take place from May 12 - 16, 2025, with sessions from 8:45 am to 12 pm ET each day and afternoon workshops starting at 1 pm ET.Enhance your knowledge of advanced screening techniques and improve accuracy and efficiency in measuring benzodiazepines. Register now to elevate your skills and stay ahead in the field of analytical chemistry!<blockquote>Presenter: François Espourteille (Application Development Manager, Bruker Applied Mass Spectrometry)François Espourteille brings over 25 years of expertise in LC-MSMS applications. He earned a BS and MS from The College of William and Mary in Virginia and received a PhD from Rutgers University, followed by a post-doctoral position at Rensselaer Polytechnic Institute. He joined Cohesive Technologies of Franklin, MA in the application group and subsequently managed the application group for Aria and Transcend platforms within Thermo Fisher Scientific until 2014.For the following decade, François has focused on clinical/toxicological LC-MSMS assays, high-throughput workflows, and 2D LCMS platforms as a consultant. He joined Bruker Applied Mass Spectrometry (BAMS) in 2021 as the DART-MS and Triple Quadrupole Application Manager.Presenter:&nbsp;Jeff Zonderman (Senior Vice President of Bruker Applied Mass Spectrometry)Jeffrey Zonderman serves as the Senior Vice President of Bruker Applied Mass Spectrometry, a new division of the company focused on providing mass spectrometry-based solutions for the applied market segments such as forensics, food, environmental, industrial/polymer, and clinical research. Jeffrey graduated from Northeastern University with a bachelor’s in biology and has been involved in mass spectrometry and chromatography for over 30 years. Before joining Bruker, Jeffrey worked in applications, sales/marketing and general management roles. His previous position was CEO of IonSense Inc, a company focusing on ambient ionization technology and commercialized DART (Direct Analysis in Real Time) technology. As Senior VP of Bruker Applied MS, Jeffrey looks to expand the applications of DART technology, amongst others, for chromatography-free mass spectrometry-based workflows.</blockquote>

Bruker: Rapid DART-MS Screen for Benzodiazepines in Urine Enabled by DART (Direct Analysis in Real Time) Technology

Rapid DART-MS Screen for Benzodiazepines in Urine Enabled by DART (Direct Analysis in Real Time) Technology

Discover power of DART-MS in providing selective results, reducing false positives and negatives, and enabling rapid addition of new target analytes.

Rapid DART-MS Screening of Benzodiazepines in Urine

<h4>An introduction to accurate mass and Quadrupole-Time-of-Flight technology with SCIEX</h4>Until recently, nominal mass triple quadrupole technology was considered the gold standard for quantitative assays. In contrast, high-resolution mass spectrometry was primarily used for qualitative, semi-quantitative, and non-targeted workflows, such as metabolite identification, screening, and X-Omics. However, advancements in technology, including faster scan speeds and improved ion optics, have expanded the capabilities of high-resolution spectrometry. Now, it can be effectively applied to both qualitative and quantitative workflows.&nbsp;The ZenoTOF 7600 system, with its high scan rates and enhanced duty cycle at the MS2 level, bridges the gap between these approaches, offering a greater return on investment by reducing data acquisition times and maintaining sensitivity without compromising data quality. This webinar series will focus on how to transition from the Triple Quad to a high-resolution environment for different applications.This webinar series will contain 3 parts. Each part will be 20 minutes with a 10 minute Q&amp;A.<h4>Part 1: Fundamentals of accurate mass</h4><ul><li>Theory behind accurate mass</li><li>How accurate mass works</li><li>Acquisition capabilities&nbsp;</li></ul><blockquote>Presenter: Jessica Smith (Market Development Manager Software EMEAI, SCIEX)Jessica joined SCIEX in 2021 as a technical marketing specialist; her responsibilities included managing projects throughout EMEAI and creating new technical marketing content. Her current role is Marketing Development Manager Software EMEAI, educating customers on the transition from Analyst software to SCIEX OS software. Jessica also studied for a Ph.D. in materials chemistry for environmental applications.</blockquote>

SCIEX: An introduction to accurate mass and Quadrupole-Time-of-Flight technology with SCIEX

Fundamentals of accurate mass

Join SCIEX specialists to learn about theory behind accurate mass and how accurate mass works.

Titration is a classic yet evolving technique. Whether you're tackling weak acids, complex matrices or low concentrations, modern titration methods offer smarter, faster solutions. In this educational webinar, we’ll explore how new approaches to titration are used to open doors in sectors like batteries, semiconductors and specialty chemicals. Conductometric titration for precise determination of weak acids and halides and thermometric titration for high-concentration acid mixture samples, are just two examples that show how titration has evolved over time.Join Eduardo Simões, Product Specialist for Titration, and Scott Segro, Senior Scientist, as they showcase the latest sensors, share real-world case studies and explain how flexible, integrated systems can transform your lab’s productivity. From customizing workflows to solving tough applications, this session is packed with practical insights. Stick around for a live Q&amp;A to ask your toughest titration questions, our experts are ready for them.Key Learning Objectives:<ul><li>Understand how conductometric and thermometric titrations work, and when to use them</li><li>Explore new sensors and their applications in challenging or emerging sample types</li><li>Learn how to customize titration workflows, including integration with other analytical techniques</li></ul>Who Should Attend:<ul><li>Those who want to stay up to date on the latest in automatic titration techniques and sensors</li><li>If you want to learn novel applications applied for emerging technologies</li><li>Those interested in discovering customization possibilities with titration including low-volume analysis and integration with other techniques</li></ul><blockquote>Presenter: Eduardo Simões, MSc (Titration Product Specialist, Metrohm USA)Presenter: Scott Segro, PhD (Senior Scientist, Metrohm USA)</blockquote>

C&EN: What’s New in Titration: New Techniques, Applications and Integration

What’s New in Titration: New Techniques, Applications and Integration

Join experts as they showcase the latest sensors, share real-world case studies

Titration News: Techniques, Applications and Integration

Have you ever felt frustrated by inconsistent pH readings despite meticulously following procedures, only to find that the results don’t match your expectations?You're not alone! Many professionals like you grapple with hidden errors in their pH measurements, leading to costly mistakes, wasted time, and a lack of confidence in their data. But what if we told you that the key to precise and reliable pH readings is just a few insights away?In our upcoming live webinar, we will unveil the hidden culprits that may sabotage your pH measurements. You’ll learn to identify and tackle potential error sources, transforming your approach to pH testing.The webinar will guide you on the path to achieving the 3Rs:<ul><li>Refined Results: Learn to minimize both systematic and random errors in your pH measurements.</li><li>Improved Repeatability: Achieve consistent results you can count on every single time.</li><li>Increased Reliability: Build confidence in your data and elevate your lab’s performance.</li></ul>Don't miss out on this opportunity to transform your pH measurement practices. Register now and take the first step towards achieving results you can trust!Event Program<ul><li>Common Sources of pH Measurement Errors</li><li>Tips for Precise pH Calibration and Verification</li><li>Sensor Maintenance and Troubleshooting</li><li>Best Measurement Practices</li><li>Data Management Techniques</li><li>An Overview of USP 791</li><li>An Interactive Expert Q&amp;A Session</li></ul><blockquote>Presenter: Dr. Reena MascarenhasDr. Mascarenhas is a seasoned electrochemist with over 5 years of dedicated experience at METTLER TOLEDO. Her in-depth knowledge and expertise in the field have made her a sought-after speaker for live webinars. With a strong academic foundation and a passion for electrochemical advancements, Dr. Mascarenhas is committed to sharing her insights and contributing to the growth of the scientific community.</blockquote>

Mettler Toledo: Reduce Your pH Measurement Errors for Consistent Results

Reduce Your pH Measurement Errors for Consistent Results

In webinar, we will unveil the hidden culprits that may sabotage your pH measurements. You’ll learn to identify and tackle potential error sources

<h4>Overview</h4>In this webinar, we will address the main LC-MS/MS solutions for the determination of short chain PFAS compounds alone or in combination with the analysis of medium- to long-chain PFAS. The webinar is aimed at everyone involved in the development of analytical methods for the analysis of PFAS, Ultra Short Chain PFAS, and TFA, with the goal of minimizing instrumental contamination from PFAS.&nbsp;<h4>Key Learning Points</h4><ul><li>Walk through a PFAS chemistry overview</li><li>Review Short Chain PFAS and TFA: Contamination Management</li><li>Understand emerging analytical solutions</li><li>Learn how to combine Short chain PFAS and “conventional” PFAS</li></ul><h4>Who Should Attend</h4><ul><li>All scientists and researchers, interested in or currently conducting PFAS analysis</li></ul><blockquote>Speaker: Sam Lodge (Senior Business Development Manager, Environmental, Phenomenex)Sam Lodge is the Phenomenex Senior Business Development Manager for the Environmental industry. He has been at Phenomenex for over 30 years in various positions, including Key Account Manager and Senior International Sales Manager, and is a product expert in SPE and HPLC chemistries. Over the past 8 years he has worked extensively with commercial and government labs in the development and support of PFAS analytical methods, including the validation of EPA 533, the MLV for DM 1633, and many internal (MOD) methods. Sam was instrumental in the collaborations that led to the development of several new SPE formats for PFAS, including several different Stacked Tubes and Pass Through GCB cartridges that can help commercial labs to increase productivity and reduce costs. In his spare time Sam enjoys fishing and surfing (but not at the same time!)Speaker: Luigi Margarucci, PhD (EMEA Seminar and Application Lead, Phenomenex)Luigi holds a PhD in Pharmaceutical Sciences and began his career at Phenomenex in 2015. He gained experience in the field of chromatography coupled with mass spectrometry while working as a researcher/fellow at the University of Salerno and collaborating with major reference centers for chromatography and mass spectrometry in Italy and Europe (Utrecht University - NL). To date, he is the author of 27 scientific publications and has written and presented a huge number of seminars on analytical techniques such as LC (LCMS), GC, and SPE.</blockquote>

Phenomenex: Alternative Method Parameters for PFAS Short Chain Detection

Alternative Method Parameters for PFAS Short Chain Detection

In this webinar, we will address the main LC-MS/MS solutions for the determination of short chain PFAS compounds

Alternative Methods for PFAS Short Chain Detection

<div>Join us for a comprehensive exploration of the pressing issues surrounding emerging contaminants, including microplastics and PFAS, and discover innovative solutions to ensure compliance and safety in water analysis and environmental monitoring. This dual webinar series will delve into the environmental and health impacts of these contaminants, highlighting cutting-edge technologies and analytical methods.In the first session, "Emerging Contaminants in Focus: How Sartorius' Products Ensure Compliance in Water Analysis," we will introduce the groundbreaking Arium® series solutions and Sartolab P20® Plus in-line filters from Sartorius. Our experts will provide a deep dive into PFAS contamination, discussing its origins, environmental impact, and health risks, as well as regulatory steps to control its presence. Learn how the Sartorius Arium® Water System revolutionizes PFAS detection by eliminating false positives and background noise, ensuring accurate chromatographic and spectroscopic results. Discover how the Sartolab P20® Plus filters enhance sample preparation efficiency for groundwater analysis.The second session, "Environmental Micro- and Nanoplastics on the Way to Plastics Treaty Negotiations," addresses the ubiquitous presence of micro- and nanoplastics in ecosystems and their transfer into the human diet. Explore the latest analytical techniques for detecting these plastics in environmental samples and foodstuffs, and gain insights into the challenges and innovations in measuring contamination. This session will also discuss the global negotiations on the plastics treaty and the role of scientific research in shaping policy.These webinars are essential for researchers, environmental scientists, public health experts, and policymakers committed to addressing plastic pollution and ensuring compliance with quality standards. Don't miss the opportunity to deepen your understanding of contaminants and learn how advanced technologies can transform water quality and environmental monitoring.<blockquote>Presenter: Andrew Dickinson, Ph.D. (Content Strategist, Wiley)Presenter: Dr. Kunal Kureja (Application Scientist and Project Leader, Sartorius Lab Instruments GmbH &amp; Co. KG)Presenter: Prof. Dr. Sedat Gündoğdu (Full Professor, Cukurova University, Faculty of Fisheries, Turkey)Presenter: Róisín Murtagh (Senior Content Strategist, Wiley)Presenter: Tricia Vail (LPS NA Segment Marketing Manager, Sartorius Corporation)</blockquote></div>

Wiley: Navigating the Challenges of Contaminants: Advanced Solutions and Insights on Microplastics and PFAS

Navigating the Challenges of Contaminants: Advanced Solutions and Insights on Microplastics and PFAS

Explore challenges of microplastics and PFAS. Learn solutions to ensure compliance and safety in water analysis and environmental monitoring.

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