<h4><strong>Continuing the conversation on toxicology innovation</strong></h4><p>In our ongoing toxicology blog series, we’ve explored sample preparation strategies, cutting-edge HRAM methods, innovative PaperSpray MS techniques, and productivity boosters for toxicology labs. Now, let’s take a deep dive into one of the most commonly requested yet technically challenging areas of forensic toxicology—<strong>accurate, efficient detection of THC and its metabolites</strong>.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Behind_the_Bench_Tips_to_Simultaneously_Analyze_THC_Its_Metabolites_and_Other_Drugs_of_Abuse_Using_LC_MS_84c59fe1e6.jpg" alt="Thermo Fisher Scientific - Behind the Bench - Tips to Simultaneously Analyze THC, Its Metabolites, and Other Drugs of Abuse Using LC-MS.jpg" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Behind_the_Bench_Tips_to_Simultaneously_Analyze_THC_Its_Metabolites_and_Other_Drugs_of_Abuse_Using_LC_MS_84c59fe1e6.jpg 245w," sizes="100vw" width="1024" height="512"></p><h3><strong>The challenge: THC’s lipophilic nature and matrix effects</strong></h3><p>Tetrahydrocannabinol (THC) remains one of the most frequently detected drugs in forensic testing after alcohol. Yet, its strong lipophilic properties make reliable measurement by LC-MS particularly challenging. THC and its metabolites tend to adhere to nonpolar surfaces of consumables and biological matrices, often leading to signal loss or inconsistent recovery.</p><p>The latest Thermo Fisher Scientific smart note demonstrates how strategic sample handling and consumable selection can mitigate these challenges. By maintaining methanol (MeOH) in every step of the extraction process—from collection through elution—analysts can prevent THC adsorption and improve recovery. For example, <strong>increasing MeOH content during sample prep and using a 30% MeOH wash step</strong> helped boost signal strength dramatically.</p><h3><strong>Extraction optimization: simple tweaks, big gains</strong></h3><p>The study’s workflow employed <strong>DPX XTR tips</strong> with mixed-mode SCX/WAX chemistry, analyzed on the Thermo Scientific <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/744"><strong>Vanquish Horizon UHPLC system</strong> </a>and Thermo Scientific <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1149"><strong>Stellar mass spectrometer</strong></a>. Four small but impactful changes—raising MeOH concentration, adjusting the SPE wash, switching to a biphenyl column, and altering the solvent reconstitution order—resulted in a <strong>sevenfold increase in THC signal intensity (Figure 1)</strong>.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Behind_the_Bench_Tips_to_Simultaneously_Analyze_THC_Its_Metabolites_and_Other_Drugs_of_Abuse_Using_LC_MS_2_ae1c729642.jpg" alt="Thermo Fisher Scientific: Behind the Bench: Tips to Simultaneously Analyze THC, Its Metabolites, and Other Drugs of Abuse Using LC-MS: Figure 1. THC signal in extracted oral fluid sample before and after changes were made to increase signal by 7x." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Behind_the_Bench_Tips_to_Simultaneously_Analyze_THC_Its_Metabolites_and_Other_Drugs_of_Abuse_Using_LC_MS_2_ae1c729642.jpg 245w," sizes="100vw" width="800" height="334"></p><p>These incremental adjustments underscore how critical it is to balance organic composition and consumable materials for each matrix type. For oral fluid assays, using <strong>silanized glass vials</strong> and incorporating <strong>Quantisal™ collection buffers</strong> can also prevent degradation and significantly improve stability—up to <strong>150× higher THC signal compared to common buffers (Figure 2)</strong>.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Behind_the_Bench_Tips_to_Simultaneously_Analyze_THC_Its_Metabolites_and_Other_Drugs_of_Abuse_Using_LC_MS_3_7fc8699115.jpg" alt="Thermo Fisher Scientific: Behind the Bench: Tips to Simultaneously Analyze THC, Its Metabolites, and Other Drugs of Abuse Using LC-MS: Figure 2. Extracted ion chromatogram of THC using common oral fluid buffer compared to Quantisal extraction buffer." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Behind_the_Bench_Tips_to_Simultaneously_Analyze_THC_Its_Metabolites_and_Other_Drugs_of_Abuse_Using_LC_MS_3_7fc8699115.jpg 245w," sizes="100vw" width="800" height="276"></p><h3><strong>Ensuring stability and recovery</strong></h3><p>Beyond extraction, analyte stability is another make-or-break factor. THC degrades quickly in standard plastic vials or at room temperature but can remain stable <strong>6–12 months when stored at –20°C in sodium heparin tubes</strong>. The Smart Note also provides practical recovery assessments for extraction development, including <strong>dry down tests</strong> and <strong>sequential elution testing</strong>, to ensure that each analyte is retained through every stage of the workflow.</p><p>By quantifying pre- and post-extraction spikes, analysts achieved <strong>high percent drug recovery</strong> and low LOQ’s across a 31-drug oral fluid panel, meeting or exceeding clinical cutoff requirements.</p><h3><strong>Isomer separation: Δ⁸-THC vs. Δ⁹-THC</strong></h3><p>With emerging cannabinoids on the market, separating Δ⁸-THC and Δ⁹-THC is increasingly important. The note highlights that <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=346&amp;manufacturerItems=3&amp;search=pfp"><strong>Pentafluorophenyl (PFP) columns</strong></a>—paired with a water/methanol mobile phase containing 0.1% formic acid—can efficiently resolve these isomers. Using a <strong>Vanquish Horizon UHPLC coupled to a </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/403"><strong>Thermo Scientific™ Orbitrap Exploris™ 120 MS</strong></a>, researchers achieved clear chromatographic separation (Figure 3).</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Behind_the_Bench_Tips_to_Simultaneously_Analyze_THC_Its_Metabolites_and_Other_Drugs_of_Abuse_Using_LC_MS_4_cf9379f345.jpg" alt="Thermo Fisher Scientific: Behind the Bench: Tips to Simultaneously Analyze THC, Its Metabolites, and Other Drugs of Abuse Using LC-MS: Figure 3. Extracted ion chromatogram of Δ8-THC-COOH and Δ9-THC-COOH separation." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Behind_the_Bench_Tips_to_Simultaneously_Analyze_THC_Its_Metabolites_and_Other_Drugs_of_Abuse_Using_LC_MS_4_cf9379f345.jpg 245w," sizes="100vw" width="800" height="328"></p><h3><strong>The takeaway: Building a robust, reliable THC assay</strong></h3><p>The bottom line? Including THC and its metabolites within a broader LC-MS drug panel is not only cost-effective but also critical to modern toxicology workflows. With deliberate choices in <strong>solvent composition, consumables, column chemistry, and buffer systems</strong>, laboratories can dramatically enhance recovery and detection reliability.</p><p>These “behind the bench” optimizations, rooted in real-world forensic workflows, illustrate how small procedural changes can deliver big performance improvements.</p><h3><strong>Continue your toxicology journey</strong></h3><p>Stay tuned for the next post in our <i>Analyte Guru</i> series and learn more on our website: <a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/content/lifetech/global/en/home/industrial/forensics/forensic-toxicology.html"><strong>Forensic Toxicology</strong></a>.</p><h3><strong>Resources</strong></h3><ul><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/content/lifetech/global/en/home/industrial/forensics/forensic-toxicology/drug-screening-confirmation/workflows.html"><strong>Drug screening and confirmation workflows</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1149"><strong>Stellar Mass Spectrometer</strong></a> &amp; <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/403"><strong>Orbitrap Exploris 120 MS</strong></a> webpages</li><li>Promotions<ul><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/content/lifetech/global/en/home/o/b/clinical-lcms-discounts.html"><strong>Save up to 40% on complete LC-MS toxicology configurations</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/content/lifetech/global/en/home/industrial/mass-spectrometry/mass-spectrometer-price-affordability-programs.html"><strong>Mass spectrometer affordability programs</strong></a><ul><li>Refurbished MS</li><li>Trade-in</li><li>Financing/ leasing</li></ul></li></ul></li><li>Past blogs in this series<ul><li>Sample prep – <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/6189"><strong>Sample Preparation Strategies Demystified: Choosing the Right Fit for Your Toxicology Workflow</strong></a></li><li>T<span style="color:initial;">ox Explorer – </span><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/6587"><strong>Beyond Blood: Sheffield Teaching Hospitals NHS Foundation Trust Develops HRAM-Powered Method for Post-Mortem Toxicology Analysis</strong></a></li><li>V<span style="color:initial;">eriSpray – </span><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/6860"><strong>Advancing Drug Analysis with PaperSpray MS</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/6953"><strong>Boosting Productivity in Toxicology Labs</strong></a></li></ul></li><li>On-demand workshop – <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/4735"><strong>Next-Generation Workflows for Small Molecule Quantitation Using the Thermo Scientific Stellar Mass Spectrometer</strong></a></li><li><strong><u>Featured content</u></strong>: <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/sn_004171_cl_lsms_stellar_thc_sn004171_na_en_62724465f8.pdf"><strong>Tips and tricks smartnote</strong></a></li></ul><blockquote><p><strong>Visit us on&nbsp;</strong><a target="_blank" rel="noopener noreferrer" href="https://www.linkedin.com/showcase/72003132/admin/dashboard/"><strong><u>LinkedIn:</u></strong></a>&nbsp;#THC #LCMS #DrugsOfAbuse #DoA</p></blockquote>

Behind the Bench: Tips to Simultaneously Analyze THC, Its Metabolites, and Other Drugs of Abuse Using LC-MS

<p><strong>The 44th International Symposium on Capillary Chromatography (ISCC), the premier meeting for pressure and electrodriven microcolumn separations and related techniques, will be held May 17 – 22, 2026 in the Congress Centre, Riva del Garda, Italy.</strong></p><p>The program will include plenary lectures, keynote lectures by young scientists, prominently featured poster presentations, an instrument exhibition displaying the latest instrumental innovations, and a highly attractive social program offering opportunities to meet with world-renown scientists.</p><p>The <strong>21st GCxGC Symposium</strong> will be organized jointly with the ISCC meeting to allow scientists to attend both meetings. The symposium will start with a short course on Sunday May 17 covering the fundamentals and applications of comprehensive GCxGC and with a plenary session on <strong>Monday May 18</strong>. Key-note lectures and posters will be included in the program of the ISCC meeting.</p><p><strong>This year particular emphasis will be directed to all Comprehensive Separation Technologies and MS Hyphenation and to capillary chromatography and 2D GC with various forms of MS from unit-mass to high resolution, and from single to hybrid analyzers</strong>, nano and capillary LC, miniaturized sample preparation by introducing a strong focus on data analytics and sustainable technology while emphasizing practical applications.</p><h2><strong>Program</strong></h2><blockquote><p class="cke-user_style-important"><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/024_Program_RIVA_2026_240426_5e66155e99.pdf"><strong>Download Symposia Program</strong></a></p></blockquote><h3><strong>44th ISCC program</strong></h3><blockquote><p class="cke-user_style-important"><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/paper/33228"><strong>Download the 44th ISCC symposium program</strong></a></p></blockquote><h4><strong>Tuesday, 19 May</strong></h4><h5><strong>09:00 – 09:25 Opening Address 44th ISCC</strong></h5><ul><li>Location: Room Garda</li></ul><h5><strong>09:25 – 10:35 Session 1 | Awards Presentation and Lectures</strong></h5><ul><li>Location: Room Garda</li></ul><h5><strong>09:25 – 10:00&nbsp;M.J.E. Golay Award Presentation and Lecture&nbsp;</strong></h5><ul><li>Sponsored by Chromaleont and RIC Group.</li></ul><h5><strong>10:00 – 10:35 ASAC Fritz Pregl Medal Presentation and Lecture</strong>&nbsp;</h5><ul><li>Assigned by Austrian Society of Analytical Chemistry (ASAC).</li></ul><h5><strong>10:35 – 11:05 Coffee Break</strong></h5><h5><strong>11:05 – 13:00 Session 2 | NANO AND CAPILLARY LIQUID CHROMATOGRAPHY</strong></h5><ul><li>Location: Room Garda</li></ul><h5><strong>13:00 – 14:00 Lunch</strong></h5><h5><strong>14:00 – 15:20 Session 3 | MULTIDIMENSIONAL AND OTHER COMPREHENSIVE TECHNIQUES</strong></h5><ul><li>Location: Room Garda</li></ul><h5><strong>15:20 – 16:50 Coffee Break – Exhibition – Vendor Seminars – Posters</strong></h5><ul><li>LECO</li><li>SPECTRA Analysis</li></ul><h5><strong>16:50 – 18:35 Session 4 | SUPERCRITICAL FLUID CHROMATOGRAPHY AND CONTAMINANTS</strong></h5><ul><li>Location: Room Garda</li></ul><h4><strong>Wednesday, 20 May</strong></h4><h5><strong>09:00 – 10:50 Session 5 | CAPILLARY GC 1</strong></h5><ul><li>Location: Room Garda</li></ul><h5><strong>09:00 – 10:50 Session 6 | HYPHENATED TECHNIQUES</strong></h5><ul><li>Location: Room Dolomiti</li></ul><h5><strong>10:50 – 12:30 Coffee Break – Vendor Seminars – Exhibition – Posters</strong></h5><ul><li>Shimadzu</li><li>RESTEK</li><li>ENTECH Instruments</li><li>LNI</li><li>GERSTEL</li><li>NIMFAST Technologies</li></ul><h5><strong>12:30 – 13:30 IUPAC Project Round Table Discussion</strong></h5><h5><strong>Greenness of official sample preparation methods</strong></h5><ul><li>Location: Room Dolomiti</li></ul><h5><strong>12:30 – 14:00 Lunch</strong></h5><h5><strong>14:00 – 15:20 Session 7 | COLUMN TECHNOLOGY</strong></h5><ul><li>Location: Room Garda</li></ul><h5><strong>14:00 – 15:20 Session 8 | BIO - PHARMA</strong></h5><ul><li>Location: Room Dolomiti</li></ul><h5><strong>15:20 – 16:40 Coffee Break – Vendor Seminars – Exhibition – Posters</strong></h5><ul><li>Agilent</li><li>VUV Analytics</li><li>Da Vinci</li></ul><h5><strong>16:40 – 18:10 Young Session 1</strong></h5><ul><li>Location: Room Garda</li></ul><h5><strong>16:40 – 18:10 Young Session 2</strong></h5><ul><li>Location: Room Dolomiti</li></ul><h4><strong>Thursday, 21 May</strong></h4><h5><strong>09:00 – 11:05 Session 9 | DAC SAMPLE PREPARATION STUDY GROUP AND NETWORK</strong></h5><ul><li>Location: Room Garda</li></ul><h5><strong>09:00 – 11:05 Session 10 | CAPILLARY GC 2 - AUTOMATION - SAMPLING SYSTEM</strong></h5><ul><li>Location: Room Dolomiti</li></ul><h5><strong>11:05 – 12:30 Coffee Break – Vendor Seminars – Exhibition – Posters</strong></h5><ul><li>MERCK</li><li>SRA Instruments</li><li>JEOL</li></ul><h5><strong>12:30 – 13:30 Round Table</strong></h5><h5><strong>Capillary LC Separations - On the Horizon and Beyond</strong></h5><ul><li>Location: Room Dolomiti</li></ul><h5><strong>12:30 – 14:00 Lunch</strong></h5><h5><strong>14:00 – 15:35 Session 11 | MINIATURIZED SAMPLE PREPARATION 1</strong></h5><ul><li>Location: Room Garda</li></ul><h5><strong>14:00 – 15:35 Session 12 | METABOLOMICS - ARTIFICAL INTELLIGENCE</strong></h5><ul><li>Location: Room Dolomiti</li></ul><h5><strong>15:35 – 16:55 Coffee Break – Vendor Seminars – Exhibition – Posters</strong></h5><ul><li>Waters Corporation</li><li>SEPSOLVE (MARKES)</li><li>F-DGSi</li></ul><h5><strong>16:55 – 18:25 Young Session 3</strong></h5><ul><li>Location: Room Garda</li></ul><h5><strong>16:55 – 18:25 Young Session 4</strong></h5><ul><li>Location: Room Dolomiti</li></ul><h4><strong>Friday, 22 May</strong></h4><h5><strong>09:00 – 10:20 Session 13 | NATURAL PRODUCTS, FOOD, FLAVOURS AND FRAGRANCES</strong></h5><ul><li>Location: Room Garda</li></ul><h5><strong>09:00 – 10:20 Session 14 | MINIATURIZED SAMPLE PREPARATION</strong></h5><ul><li>Location: Room Dolomiti</li></ul><h5><strong>10:20 – 10:50 Coffee Break – Exhibition</strong></h5><h5><strong>10:50 – 12:10 Session 15 | INSTRUMENTATION</strong></h5><ul><li>Location: Room Garda</li></ul><h5><strong>10:50 – 12:10 Session 16 | ELECTROMIGRATION METHODS</strong></h5><p>Location: Room Dolomiti</p><h5><strong>12:10 – 12:50 Closing Address 44th ISCC</strong></h5><ul><li>Location: Room Garda</li></ul><p><strong>Presentation of the:</strong></p><ul><li>GENZO SHIMADZU Oral Awards</li><li>ABC Springer Best Poster Awards (Young Scientists)</li><li>Analytical Methods RSC Best Poster Award (Young Scientists)</li><li>Green Analytical Chemistry Elsevier Best Poster Awards</li><li>Molecules MDPI Best Oral Award (Young Scientists)</li></ul><h3><strong>21st GCxGC program</strong></h3><blockquote><p class="cke-user_style-important"><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/paper/33227"><strong>Download the 21st GCxGC symposium program</strong></a></p></blockquote><h4><strong>Monday, 18 May</strong></h4><h5><strong>08:30 – 08:45 Opening Address 21st GC×GC</strong></h5><ul><li>Location: Room Garda</li></ul><h5><strong>08:45 – 10:50 Session 1 | Awards Presentation and Lectures</strong></h5><ul><li>Location: Room Garda</li></ul><h5><strong>08:45 – 10:00&nbsp;&nbsp;&nbsp;&nbsp;Lifetime Achievement Award Presentations and Lectures</strong></h5><ul><li>Sponsored by SepSolve Analytical, Markes International and LECO.</li></ul><h5><strong>10:00 – 10:50&nbsp;&nbsp;&nbsp;&nbsp;John Phillips Award Presentations and Lectures&nbsp;</strong></h5><ul><li>Sponsored by LECO</li></ul><h5><strong>10:50 – 11:20 Coffee Break</strong></h5><h5><strong>11:20 – 13:15 Session 2 | FUNDAMENTALS 1</strong></h5><ul><li>Location: Room Garda</li></ul><h5><strong>11:20 – 13:15 Session 3 | FOOD 1</strong></h5><ul><li>Location: Room Dolomiti</li></ul><h5><strong>13:15 – 14:15 Lunch Break</strong></h5><h5><strong>14:15 – 16:10 Session 4 | ENVIROMENTAL</strong></h5><ul><li>Location: Room Garda</li></ul><h5><strong>14:15 – 16:10 Session 5 | BIO-ANALYTICAL - ARTIFICIAL INTELLIGENCE</strong></h5><ul><li>Location: Room Dolomiti</li></ul><h5><strong>16:10 – 16:40 Coffee Break</strong></h5><h5><strong>16:40 – 18:50 Young Session 1</strong></h5><ul><li>Location: Room Garda</li></ul><h5><strong>16:40 – 18:50 Young Session 2</strong></h5><ul><li>Location: Room Dolomiti</li></ul><h4><strong>Tuesday, 19 May</strong></h4><h5><strong>11:05 – 13:00 Session 6 | FUNDAMENTALS 2 AND FOOD 2</strong></h5><ul><li>Location: Room Dolomiti</li></ul><h5><strong>13:00 – 14:00 Lunch</strong></h5><h5><strong>14:00 – 15:20 Session 7 | PETROCHEMICAL</strong></h5><ul><li>Location: Room Dolomiti</li></ul><h5><strong>15:20 – 16:50 Coffee Break - Exhibition – Vendor Seminars – Posters</strong></h5><ul><li>LECO</li><li>SPECTRA Analysis</li></ul><h5><strong>16:50 – 18:35 Session 8 | INDUSTRY - VOCs</strong></h5><ul><li>Location: Room Dolomiti</li></ul><h5><strong>18:35 – 18:50 Closing Address 21th GC×GC</strong></h5><ul><li>Location: Room Dolomiti</li></ul><p><strong>Presentation of the:</strong></p><ul><li>RICHARD SACKS BEST POSTER AWARDS (sponsored by LECO)</li><li>GENZO SHIMADZU Oral Awards</li><li>ABC Springer Best Poster Award (Young Scientists)</li><li>Separations MDPI Best Oral Award (Young Scientists)</li></ul>

Program of the 44th International Symposium on Capillary Chromatography and 21st GCxGC Symposium

<p><strong>The MDCW is a premier annual event with FREE registration, bringing together experts and enthusiasts in the field of multidimensional chromatography. Established in 2005, MDCW serves as a platform for professionals and newcomers to share cutting-edge research, discuss technological advancements, and explore innovative applications of multidimensional chromatographic techniques.&nbsp;</strong></p><blockquote><p>📍 <strong>Liège, Belgium</strong><br>📅 <strong>January 25–27, 2027</strong></p></blockquote><h4><strong>This in-person event will feature:</strong></h4><ul><li><strong>Keynote presentations</strong> from leading researchers</li><li><strong>Flash talks and poster sessions</strong> highlighting the latest innovations</li><li><strong>Focus group discussions</strong> addressing current challenges and future developments</li><li><strong>FREE registration </strong>ensures that this event remains accessible to all researchers, students, and industry professionals interested in multidimensional chromatography. ​​We hope to see you there!</li></ul><h4><strong>Organizing Committee</strong></h4><ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/articles?search=Katelynn+Perrault+Uptmor"><strong>Katelynn Perrault Uptmor</strong></a> (William &amp; Mary, Associate Professor)</li><li>Pierre-Hugues Stefanuto (University of Liège, Senior Scientist)</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/articles?search=%E2%80%8BDwight+Stoll"><strong>​Dwight Stoll</strong></a> (Gustavus Adolphus College, Professor)&nbsp;</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/articles?search=petr+vozka"><strong>Petr Vozka</strong></a> (Cal State LA, Associate Professor)</li></ul><blockquote><h5><strong>The content and recordings of lectures from previous years</strong></h5></blockquote><blockquote><ul><li>💡<a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/events/787"><strong>17th Multidimensional Chromatography Workshop (MDCW)</strong></a><ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/article/6702"><strong>Short Course (Day 0)</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/article/6706"><strong>Day 1</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/article/6712"><strong>Day 2</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/article/6713"><strong>Day 3</strong></a></li></ul></li><li>💡<a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/events/518"><strong>16th Multidimensional Chromatography Workshop (MDCW)</strong></a>&nbsp;<ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/article/4965"><strong>Short Course (Day 0)</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/article/4967"><strong>Day 1</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/article/4971"><strong>Day 2</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/article/4974"><strong>Day 3</strong></a></li></ul></li><li>💡 <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/playlist?list=PLg-M6fM-05MrGrDggkl_UKzzcHPWPmssh">LabRulez YouTube channel: <strong>The Multidimensional Chromatography (MDC) Workshop playlist</strong></a> with recorded presentations</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/companies/218"><strong>LabRulezGCMS profile</strong></a><strong>: The Multidimensional Chromatography (MDC) Workshop</strong></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/218"><strong>LabRulezLCMS profile</strong></a><strong>: The Multidimensional Chromatography (MDC) Workshop</strong></li></ul></blockquote><h3><strong>​Key Dates</strong></h3><ul><li><strong>​June 1, 2026: </strong>Abstract submission opens</li><li><strong>​June 30, 2026</strong>: Sponsorship agreement deadline</li><li>​<strong>July 2026:</strong> Registration opens</li><li><strong>September 1, 2026: </strong>Deadline for abstract submission</li><li><strong>September 30, 2026:</strong> Notification of abstract acceptances</li><li><strong>November 1, 2026: </strong>Preliminary program release</li><li><strong>November 30, 2026:</strong> Deadline for last-minute posters</li><li><strong>December 1, 2026:</strong> Registration deadline and final program release</li><li><strong>January 24, 2027: </strong>Short Course (registration details forthcoming)</li><li><strong>January 25-27, 2027:</strong> Conference dates</li></ul><h3><strong>Call for Sponsors</strong></h3><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/18mdcw_CFS_2_1e57031877.jpg" alt="18th Multidimensional Chromatography Workshop (MDCW): Call for Sponsors" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_18mdcw_CFS_2_1e57031877.jpg 245w," sizes="100vw" width="1600" height="900"></p><ul><li><strong>Free registration</strong></li><li>Tiered <strong>sponsor packages</strong> available (Platinum, Gold, Silver)</li><li><strong>Sponsorship deadline:</strong> June 30, 2026</li></ul><h4><span><strong>Highlights</strong></span></h4><ul><li><strong>Growing attendance</strong> year-over-year</li><li>Engage directly with end-users and decision-makers</li><li>Recruit top undergraduate and graduate talent</li><li>Build brand visibility</li><li>Receive <strong>real-time feedback</strong> from expert users</li><li>Online content has <strong>&gt;50,000 views on LabRulez platform</strong></li></ul><h4><span><strong>Previous years (2024–2026)</strong></span></h4><ul><li>467 attendees</li><li>104 oral presentations</li><li>94 poster presentations</li><li>5 guided discussions</li></ul><h4><strong>17th Multidimensional Chromatography Workshop (MDCW) 2026 Sponsors</strong></h4><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/17th_Multidimensional_Chromatography_Workshop_MDCW_2026_Sponsors_1859423718.jpg" alt="17th Multidimensional Chromatography Workshop (MDCW) 2026: Sponsors" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_17th_Multidimensional_Chromatography_Workshop_MDCW_2026_Sponsors_1859423718.jpg 124w," sizes="100vw" width="888" height="1119"></p><h5><strong>Platinum</strong></h5><ul><li>LECO</li></ul><h5><strong>Gold</strong></h5><ul><li>VICI DBS</li><li>NXT Power</li><li>GL Sciences</li></ul><h5><strong>Silver</strong></h5><ul><li>TRAJAN</li><li>GC Image</li><li>Markes International</li><li>SepSolve</li><li>RESTEK</li></ul><h5><strong>Awards Sponsor</strong></h5><ul><li>American Chemical Society (ACS) Subdivision of Chromatography and Separations Chemistry</li></ul><h5><strong>Media Sponsor</strong></h5><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/"><strong>LabRulezLCMS</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/"><strong>LabRulezGCMS</strong></a></li></ul><blockquote><p>If you have any questions or concerns, please direct emails to: <strong>multidimensionalchromatography@gmail.com</strong></p></blockquote>

18th Multidimensional Chromatography Workshop (MDCW) - Call for Sponsors

Article

Product

Events

Application

Video

The Multidimensional Chromatography (MDC) Workshop draws experts in this exciting field to share and discuss their research.

The Multidimensional Chromatography Workshop

A unique company dedicated to serving science helping our customers drive productivity and accelerate results. Through our premier brands – Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific and Unity Lab Services.

Thermo Fisher Scientific

ISCC & GC×GC Symposium bring together global experts to discuss advances in capillary and multidimensional chromatography, mass spectrometry, and analytical technologies for complex sample analysis.

International Symposium on Capillary Chromatography (ISCC) and GCxGC Symposium

Metrohm

Agilent Technologies

Technology Networks

Phenomenex

C&EN

SCIEX

KNAUER

<h3><strong>A five-part webinar series unlocking advanced insights across the Peptide therapeutics workflows</strong></h3><p><strong>Peptide therapeutics are reshaping modern medicine, with GLP-1 receptor agonists driving rapid advances in metabolic disease treatment. As peptide and GLP-1 programs scale, scientists face increasing pressure to generate data that is accurate, defensible, and decision-ready across development stages.</strong></p><p>Peptide 360 is designed to guide scientists through this complexity, following the peptide workflow from sequence insight to confident development decisions.</p><h5><strong>Who Should Attend?</strong></h5><p>This series is designed for scientists and technical leaders working in peptide and GLP-1 discovery and development, analytical development, characterization, Bioanalysis, DMPK, translational research, CMC, QA/QC, and regulatory-facing analytical roles</p><h5><strong>How the Series Works?</strong></h5><ul><li>Register once for the full series</li><li>Pre-submit questions for live expert responses</li><li>Access recordings anytime after each session</li><li>Certificate of attendance provided</li></ul><h4><strong>Episode 3: Quantifying GLP-1 Peptides in Plasma: Bioanalytical Workflows for PK and Development</strong></h4><p>As GLP-1 peptide therapeutics advance through development, understanding how these molecules behave in biological systems becomes critical. Accurate measurement of GLP-1 analogs in plasma is essential for generating reliable pharmacokinetic and toxicokinetic data. This session explores bioanalytical workflows that combine automated sample cleanup with sensitive LC/MS-based quantitation to overcome the limitations of traditional antibody-based assays.</p><p>Attendees will learn how automation and mass spectrometry enable faster method development, improved specificity, and robust quantitation in complex biological matrices. The session highlights how bioanalysis strengthens development decisions by linking molecular design to in-vivo performance.</p><blockquote><p><strong>Presenter: </strong>Xi Qiu, Ph.D. (LC-MS Application Scientist, Agilent Technologies, Inc.)</p><p><strong>Presenter:&nbsp;</strong>Ashish Pargaonkar, Ph.D. (Biopharma Applications Specialist, Agilent Technologies, Inc.)</p></blockquote>

Agilent Technologies: Peptide 360: Mastering the Invisible from Sequence to Confidence

Quantifying GLP-1 Peptides in Plasma: Bioanalytical Workflows for PK and Development

Peptide 360 Episode 3 webinar on LC-MS bioanalysis of GLP-1 peptides in plasma for PK studies and development decisions.

Quantifying GLP-1 Peptides in Plasma

<div><p><strong>High-throughput proteomics is pushing laboratories to generate deeper, more reliable data from smaller sample amounts without sacrificing speed or consistency. As workflows shorten, questions remain around maintaining quantitative accuracy and cross-lab reproducibility.</strong></p><p>This webinar examines how recent advances in liquid chromatography-mass spectrometry (LC-MS) are addressing these challenges through insights from a large multi-laboratory benchmark study using standardized proteome samples. Attendees will see how next-generation approaches can support robust, reproducible high-throughput proteomics and how publicly available benchmark datasets are helping the community evaluate and improve data analysis strategies.</p><h4><strong>Attend this webinar to:</strong></h4><ul><li>Understand how short gradient LC–MS workflows support high throughput label-free quantitation (LFQ) proteomics</li><li>Explore the role of data independent acquisition strategies in improving proteome coverage and quantitative reproducibility</li><li>Learn from a multi laboratory benchmark study using standardized proteome samples</li><li>Learn why the ZenoTOF 8600 system is perfectly positioned to support high-throughput LFQ proteomics&nbsp;</li></ul><blockquote><p><strong>Presenter:</strong> Bart Van Puyvelde, PhD (Field Application Specialist, SCIEX)</p><p>Dr. Bart Van Puyvelde is a field application specialist at SCIEX, a role he recently stepped into after completing his postdoctoral research at the Laboratory of Pharmaceutical Biotechnology at Ghent University, Belgium.</p></blockquote></div>

Technology Networks: Label Free Quantitation: New Insights Into High-Throughput Proteomic Workflows

Label Free Quantitation: New Insights Into High-Throughput Proteomic Workflows

Webinar on high-throughput LFQ proteomics using LC-MS and ZenoTOF 8600, highlighting reproducibility and multi-lab benchmark results.

Insights Into High-Throughput Proteomic Workflows

<p><strong>In biotherapeutic development, speed and confidence in impurity profiling are critical to moving candidates forward. This webinar introduces a streamlined workflow designed to accelerate impurity profiling of GLP-1 analogs. It begins with impurity screening using the new Pro IQ Plus single quadrupole mass detector. Then, detailed sequence analysis is performed using the 6545XT AdvanceBio LC/Q-TOF, equipped with an ExD cell to enable electron capture dissociation (ECD). ECD offers a gentler fragmentation approach than traditional CID, preserving labile modifications and enabling detailed structural insights.&nbsp;</strong></p><p>We highlight key advantages of ECD including modification localization, isoaspartate investigation, and discuss the importance of spectral quality in sequence confirmation. Whether you're optimizing GLP-1 analogs or exploring new biotherapeutics, this webinar highlights how Agilent’s tools can help get answers faster and go deeper with your data.</p><blockquote><p><strong>Presenter: </strong>Rachel Franklin (Application Development Scientist, Agilent Technologies, Inc.)</p><p>Rachel is an Application Development Scientist at Agilent Technologies who specializes in developing innovative applications using high resolution mass spectrometry. She joined Agilent in 2023 through the acquisition of e-MSion, the developer of the core technology for the Agilent ExD cell. Rachel earned her PhD in Biochemistry and Biophysics from Oregon State University where she focused her research on studying genetically engineered protein systems using top-down mass spectrometry. In her current role at Agilent, Rachel continues to advance research in this area and enjoys exploring new application areas.</p></blockquote>

Agilent Technologies: Accelerating GLP-1 Analog Impurity Profiling with the Agilent Pro IQ Plus Followed by Detailed Sequence Analysis using Electron Capture Dissociation

Accelerating GLP-1 Analog Impurity Profiling with the Agilent Pro IQ Plus Followed by Detailed Sequence Analysis using Electron Capture Dissociation

Fast GLP-1 impurity profiling using Pro IQ Plus and 6545XT LC/Q-TOF with ExD ECD for confident sequence analysis.

GLP-1 Analog Impurity Profiling with Agilent Pro IQ Plus

<p><strong>Join this webinar to hear from Lorena Manzano as she highlights the benefits of ZenoTOF 7600 system for the analysis of pharmaceuticals and pesticides in wastewater, soils and crops.</strong></p><p>This webinar will provide an overview of advanced high-resolution mass spectrometry (HRMS) strategies for monitoring pharmaceuticals and pesticides in complex environmental and agricultural matrices. Lorena Manzano will share recent findings on the occurrence, persistence, and potential transfer of these contaminants from reclaimed water to soils and crops, highlighting how innovative analytical solutions can support safer water reuse practices.</p><p>Water scarcity and the increasing use of reclaimed water for irrigation create both opportunities and challenges for agriculture. While reuse contributes to sustainability, it also introduces chemical contaminants into the food chain. Conventional monitoring approaches often fail to provide the sensitivity, selectivity, and robustness required to detect low-level residues in highly complex samples such as soils and edible plant tissues.</p><p>This webinar will address these challenges by discussing the role of HRMS, with a particular focus on how ZenoTOF 7600 system enhances confidence in compound identification and quantification. Attendees will learn about key trends in environmental risk assessment, the importance of tracking persistent pharmaceuticals such as carbamazepine, and the role of multi-residue analysis in ensuring food safety.</p><p>Case studies from greenhouse experiments will be presented, demonstrating real-world examples of pharmaceutical and pesticide transfer from wastewater to soils and edible crops. Finally, the session will provide actionable insights into how cutting-edge HRMS can be integrated into monitoring programs to better protect both agricultural productivity and public health.</p><h4><strong>Key learning points:</strong></h4><ul><li>Understand the occurrence and persistence of pharmaceuticals and pesticides in reclaimed water, irrigated soils, and edible crops.</li><li>Explore how ZenoTOF 7600 system enhances detection, identification, and quantification of contaminants in complex matrices.</li><li>Learn from greenhouse case studies on pharmaceutical and pesticide accumulation under real-world irrigation practices.</li><li>Identify key challenges and opportunities for safe wastewater reuse in agriculture and food safety monitoring</li></ul><blockquote><p><strong>Speaker:</strong> Lorena Manzano (PhD in Analytical Chemistry, University Almería, Spain)</p><p>Lorena is an expert in advanced chromatographic and mass spectrometric techniques. With over six years of experience at the European Union Reference Laboratory for Fruits and Vegetables (EURL-FV), her work has focused on the application of LC- and GC-based high- and low-resolution mass spectrometry for the monitoring of pesticide residues in plant-derived matrices.</p></blockquote>

SCIEX: Tracking irrigation-related contaminants in water and soils (QTOF-MS)

Tracking irrigation-related contaminants in water and soils (QTOF-MS)

Benefits of ZenoTOF 7600 system for the analysis of pharmaceuticals and pesticides in wastewater, soils and crops.

QTOF-MS Tracking contaminants in water and soils

<div><div container-id="cq-colctrl-lt0" comp-id="A1"><div><h4><strong>In situ native proteomics: Imaging and top-down analysis of intact protein complexes in tissue</strong></h4><p><strong>Join this webinar to hear about latest methods and advances for probing intact protein complexes in tissue using in situ native mass spectrometry.</strong></p><p>Native ambient mass spectrometry (NAMS) enables the study of proteins and their complexes directly in tissue. The latest developments in NAMS will be presented, including innovative MS imaging and on-tissue native top-down MS workflows.</p><p><strong>Topics will include:</strong></p><ul><li>Analysis of membrane proteins</li><li>Identification of protein-metal complexes implicated in neurodegenerative disease.</li></ul><p><i>Cannot join on April 16? Please register anyway to automatically receive access to the recording.</i></p><blockquote><p><strong>Presenter: </strong>Dr. Oliver Hale (Senior Postdoctoral Research Fellow, University of Birmingham)</p><p>Dr. Oliver Hale is a senior postdoctoral research fellow in the lab of Professor Helen Cooper at the University of Birmingham and has a secondment at the Rosalind Franklin Institute (RFI). Across both institutions, his research focus is the development of native ambient mass spectrometry (NAMS) encompassing MS imaging of intact protein complexes, native top-down MS and instrument/method development. Oliver has presented at multiple international conferences and was a tutor at the American Society for Mass Spectrometry’s Fall Workshop on Native Mass Spectrometry.</p></blockquote></div></div></div>

Thermo Fisher Scientific: Imaging and top-down analysis of intact protein complexes in tissue

Imaging and top-down analysis of intact protein complexes in tissue

Join this webinar to hear about latest methods and advances for probing intact protein complexes in tissue using in situ native mass spectrometry.

Imaging and top-down analysis of intact protein in tissue

<p><strong>This webinar explores how potential PFAS contamination can sporadically enter the analytical workflow from sample preparation through the LC chromatography system. Fluoropolymer‑based components and inadequately screened consumables frequently introduce background PFAS that can lead to false positives. While regulatory methods emphasize the importance of clean materials and rigorous blank testing to ensure PFAS‑free workflows, practical mitigation strategies can help identify potential contamination sources and outline best practices to prevent them. These strategies include using PFAS‑specialized products to support a comprehensive workflow contamination‑control approach.</strong></p><h4><strong>Key Learning Points</strong></h4><ul><li>Identify and avoid potential sources for sporadic PFAS contamination in the PFAS workflow.</li><li>Learn how to apply best practices for sample preparation and analytical instrumentation.</li><li>Gain insight into products that support effective management of PFAS contamination.</li></ul><h4><strong>Who Should Attend</strong></h4><ul><li>Any analytical professionals who are beginning or expanding their work with PFAS by LC-MS/MS across both regulated and non-regulated methods and who are navigating background contamination, method sensitivity demands, and the practical challenges of troubleshooting persistent PFAS interferences.</li></ul><blockquote><p><strong>Speaker:</strong> Maryam Sayeed (Product Manager, Phenomenex)</p><p>Maryam Sayeed is a Product Manager at Phenomenex and has been with the company for three years. She focuses on expanding solutions for chromatography products and consumables designed for the food and environmental markets. Her work also includes supporting products that address challenges associated with PFAS analysis and background contamination at low detection limits. Prior to joining Phenomenex, Maryam spent nine years in the food and beverage industry, gaining extensive hands on experience with HPLC analysis. She holds an MS in Biology with a specialization in Biochemistry.</p></blockquote>

Phenomenex: Strategies to Mitigate Sporadic PFAS Contamination in Analytical Workflows

Strategies to Mitigate Sporadic PFAS Contamination in Analytical Workflows

Webinar on PFAS contamination in LC-MS workflows—learn sources, prevention strategies, and best practices for accurate low-level PFAS analysis.

Mitigate Sporadic PFAS Contamination in Analytical Workflows

<p><strong>Join this presentation and open discussion with industry-leading experts Patrick Muller and Kieran Evans – leaders in UV/Vis and IR analytical methods and testing techniques. This talk is designed for scientists in optics development and the high-end research of optical properties who work in academia, solar, space, defense and other high-performance applications.</strong></p><h4><strong>Key Learning Objectives:</strong></h4><ul><li>Understand key measurement requirements for optical components and thin films, using both the UV/Vis/NIR and FTIR instrumentation.</li><li>Better understand material properties for real-life applications in industry, defense and the environment.</li><li>Learn about the importance of sampling flexibility in UV/Vis/NIR analysis.</li><li>See how specialist infrared equipment such as Optica can further advance your research insights including in-transmission measurements.</li></ul><h4><strong>Who Should Attend:</strong></h4><p>Scientists investigating optical properties who work in academia, solar, space, defense and other high-performance applications:</p><ul><li>Laboratory manager</li><li>Material Scientist</li><li>Research/Researcher</li><li>Optics Scientists</li><li>Principal Investigators</li><li>Lead Researcher</li></ul><blockquote><p><strong>Speaker:</strong> Kieran Evans (Product Manager – UV, PerkinElmer UK)</p><p><strong>Speaker:</strong> Dr. Patrick Müller (Product Specialist FT-IR/FT-NIR, PerkinElmer)</p><p><strong>Speaker:</strong> Sara Kobilka (Contributing Editor, C&amp;EN Media Group)</p></blockquote>

C&EN: Precision Lab Solutions for High-End Optics and Coatings

Precision Lab Solutions for High-End Optics and Coatings

Join this presentation and open discussion with industry-leading experts in UV/Vis and IR analytical methods and testing techniques.

<h4><strong>Safety isn’t optional — it’s foundational.</strong></h4><p><strong>At Agilent, Safer Labs is more than an initiative — it’s our commitment to fostering safer, healthier, and more productive laboratory environments.</strong><br><strong>Safety should be the most important criterion in every workplace, yet the understanding and implementation of safety practices often vary across individuals and teams.</strong></p><p>To build a uniform, strong, and informed safety culture, we invite you to join our upcoming Safer Labs Webinar, designed for lab professionals who are committed to elevating safety standards in their organizations.</p><h5><strong>What to Expect:</strong></h5><p>In this session, our experts will shed light on key EHS concerns that impact daily lab operations, including:</p><ul><li>Safe Handling</li><li>Safe Storage</li><li>Safe Instrumentation</li><li>Safe Usage</li><li>Safe Transportation</li><li>Safe Disposal</li></ul><p>You’ll gain actionable insights, practical guidance, and a deeper understanding of how the right practices — supported by the right tools — can dramatically reduce risks and enhance overall lab efficiency.</p><p>Agilent solutions are engineered with rigorous safety parameters, ensuring our customers and their laboratories are protected, supported, and empowered to perform at their best.</p><h5><strong>Who Should Attend?</strong></h5><ul><li>EHS Managers</li><li>Chemists</li><li>QC Teams</li><li>R&amp;D Scientists</li><li>Professionals from Pharma, Biopharma, Food &amp; Beverage, and</li><li>Environmental Analytical Testing Labs</li></ul><h5><strong>Why You Shouldn’t Miss This:</strong></h5><ul><li>Be part of a growing movement to build safer workplaces across industries.</li><li>Let’s work together to create laboratories where safety is a shared responsibility and a consistent practice, ensuring long‑term well‑being and operational excellence.</li></ul><blockquote><p><strong>Presenter:</strong> Dr. Sunil B Lakhmapure (Pre-Sales Application Engineer, Agilent Technologies)</p><p>Sunil holds 19 year plus experience in the analytical field with major exposure to LC/GC with Single Quad, Triple Quad and high resolution (QToF) mass spectroscopy. Started career in Pharma R&amp;D as a scientist with hands on experience on high end instruments like LC/MS, XRD &amp; NMR. Developed &amp; published application notes using Chromatographic techniques on real world samples/issues at various levels.</p></blockquote>

Agilent Technologies: The Journey of Safer Science through Safer Labs

The Journey of Safer Science through Safer Labs

Agilent Safer Labs webinar covers lab safety practices, EHS risks, and solutions for safer and more efficient laboratory operations.

<h4><strong>Explore the Future of Drug Delivery: Join Our Upcoming Webinar.</strong></h4><p><strong>KNAUER, in collaboration with the Massachusetts Institute of Technology (MIT), is pleased to invite you to an exclusive webinar: “Engineering Lipid Nanoparticles for Drug Delivery Using Impingement Jet Mixers”</strong></p><p>Lipid nanoparticles (LNPs) are transforming modern drug delivery – but how can they be produced efficiently and at scale? In this session, Cedric Devos (MIT) and fellow researchers will present innovative approaches using confined Impingement Jet Mixers (IJM).</p><h5><strong>What you’ll learn</strong></h5><ul><li>How rapid micromixing enables precise control over particle size and morphology</li><li>Ways to decouple key quality attributes such as encapsulation efficiency</li><li>Strategies to streamline process development and pave the way for automation</li></ul><p>Don’t miss this opportunity to gain valuable insights into technologies driving the next generation of nanoparticle manufacturing.</p>

KNAUER: Engineering Lipid Nanoparticles for Drug Delivery Using Impingement Jet Mixers

Engineering Lipid Nanoparticles for Drug Delivery Using Impingement Jet Mixers

Webinar on lipid nanoparticles and impingement jet mixing for scalable drug delivery and process optimization.

Engineering Lipid Nanoparticles Using Impingement Jet Mixers

<p><strong>The chemistry of copper plating baths is complex, and each component plays a role in the quality of the final product. The composition evolves as such baths are used and adjustment decisions must be made on reliable, relevant data.</strong></p><p>In our upcoming webinar, we present a multi‑method analytical approach as the most efficient way to develop and monitor copper deposition baths. By combining titration and cyclic voltammetric stripping (CVS) with complementary techniques such as pH measurement and X‑ray fluorescence (XRF), users gain a complete picture of their plating bath chemistry.</p><p>Each method targets a specific class of components: While titration offers a robust and efficient way to quantify the main metallic components, salts, and anions, CVS is the industry standard method for measuring the organic additives in the baths. XRF offers additional insight regarding the presence of metallic contaminants and additives.</p><p>After a close look at the specific strengths of these methods, how they complement each other, and automation options, our presenters will answer any questions you may have on the webinar topic in a Q&amp;A session.</p><h4><strong>Key learning points of this webinar:</strong></h4><ul><li>Learn the power of method combination: How tiration and CVS can be integrated with other analytical techniques like XRF and pH measurement to provide a more complete understanding of the plating bath chemistry.</li><li>The benefits of automation beyond increased throughput and general convenience: How to eliminate operator relative variance, increase repeatability, and ensure that optimzed analytical approaches can be applied consistently in multiple locations.</li><li>Why our analytical technologies are perfectly suited for the various players in this industry, from bath chemistry development to the production floor.</li></ul><h4><strong>Who should attend this webinar?</strong></h4><ul><li>Production managers that oversee the day-to-day production process</li><li>QC professionals in charge of ensuring product quality</li><li>Researchers involved in the development of new copper plating technologies and advanced bath chemistry</li></ul><blockquote><p><strong>Presenter: </strong>Dr. Julia van Drunen (Head of Competence Center, Voltammetry, Metrohm)</p><p>Julia van Drunen completed her Ph.D. in electrochemistry at Queen’s University in 2013 and worked for two years as a post-doctoral researcher at the University of Sao Paulo before joining Metrohm Autolab in the Netherlands in 2016 and Metrohm HQ in 2024. She specializes in the topics of surface electrochemistry of nickel and platinum, electrocatalysis, and the corrosion of metals and alloys.</p><p><strong>Presenter: </strong>Dr. Christian Haider (Head of Competence Center Titration, Metrohm International Headquarters)</p><p>Dr. Christian Haider joined Metrohm International Headquarters in 2002 where he started as an Application Specialist Titration. He has advanced his career at Metrohm to become Head of Competence Center Titration and in this position leads a team of Product Managers, Product Specialists, and Application Chemists for all the different titration techniques, pH and conductivity measurement, titration automation, and software.</p><p><strong>Presenter: </strong>Jeroen Zaalberg (Head of Product Management, Metrohm Applikon)</p><p>Jeroen Zaalberg joined Metrohm Process Analytics in 2008 and has worked as an application chemist, Product Manager Wet-Chemistry, and is currently in the position of Head of Product Management.</p><p>Jeroen has a BSc in analytical and physical chemistry and has a passion for product development, innovation and strategy. Over the recent years, Jeroen successfully launched several new products in the Metrohm Process Analytics portfolio.</p></blockquote>

Metrohm: Copper deposition baths: Advanced analytical solutions for development and monitoring

Copper deposition baths: Advanced analytical solutions for development and monitoring

Learn how titration, CVS, XRF, and pH measurement improve copper plating bath control, data quality, and production consistency.

Related content

Behind the Bench: Tips to Simultaneously Analyze THC, Its Metabolites, and Other Drugs of Abuse Using LC-MS

18th Multidimensional Chromatography Workshop (MDCW) - Call for Sponsors

Program of the 44th International Symposium on Capillary Chromatography and 21st GCxGC Symposium