Professor Michaela Rumlová, head of a research group of the National Institute of Virology and Bacteriology at UCT Prague (and Vice-Rector for doctoral studies), holder of a licensed patent &nbsp;for antiretroviral testing assays, and recipient of the Czech Science Foundation’s President’s Award for HIV research, has also become the principal investigator of the bilateral INTER-EXCELLENCE II project “Cellular factors regulating the export and packaging of unspliced ​​retroviral RNA”, starting this year. In this interview, she explains how retroviruses such as HIV “hack” the cell in order to export their own genome from the nucleus into the cytoplasm, and then to the site where it is specifically packaged into nascent viral particles, a key step in viral replication. Her team is collaborating with the NIH (National Institutes of Health) and Rockefeller University to elucidate mechanisms that may help reveal new vulnerable points in the retrovirus replication cycle while simultaneously clarifying related cellular processes.<h5>Could you describe your project and its main objectives?</h5>Retroviruses, such as HIV, are viruses that carry genetic information in the form of RNA; however, after entering a cell, they are able to reverse transcribe it into DNA and integrate it into the host genome. In order to replicate, they must transport their genetic information—in the form of unspliced RNA—from the nucleus into the cytosol. There, it serves both as a template for the production of viral proteins and as the genome of new viral particles. This is highly unusual, as the cell very carefully controls which RNA molecules are allowed to leave the nucleus. Normal protein-coding cellular RNAs, known as messenger RNAs (mRNAs), must undergo splicing—a processing step in which certain segments are removed—before being exported. When this process fails, mRNA that retains these segments is held back in the nucleus as part of quality control and subsequently degraded. Retroviruses have managed to outwit this cellular control machinery, allowing their unspliced RNA to pass into the cytoplasm.Our project focuses on identifying the cellular proteins that assist retroviruses in this step and on the mechanism by which protein complexes bound to viral RNA are remodelled during RNA transport. The goal is to understand how the virus uses cellular mechanisms to its advantage and how this pathway is linked to the subsequent fate of the RNA, i.e. to its translation and packaging into new viral particles.<h5>Why is this export of unspliced ​​RNA so important for retroviral replication?</h5>Because this RNA has a dual role for the virus. On the one hand, it serves as a template for synthesizing viral proteins in the cytoplasm; on the other, it represents the genetic material itself, which must be packaged into new viral particles. The virus must package its RNA genome in its unspliced form, as only this RNA contains essential sequences without which further viral replication would be impossible.Simply put: the virus needs to get a complete copy of its genetic instructions out of the nucleus. Once the viral RNA is in the cytoplasm, it can be used as a template for synthesizing viral proteins; and a portion of these RNA molecules is then selected and packaged into a new particle as a genome. We are interested in how the virus forces the cell to allow viral RNA that is, from the cell’s perspective, “unfinished,” that is unspliced, to leave the nucleus. We are also investigating how the cell and the virus together - albeit unintentionally from the cell’s perspective - determine which RNA molecule will be translated into proteins and which will be packaged as the genome. This is one of the key, yet still not fully understood, steps of retroviral replication.<h5>What do you think it was about your project that impressed the Ministry of Education, Youth and Sports’ jury the most?</h5>I believe the decisive factor was a combination of several elements. First, the reviewers were primarily interested in the scientific problem itself. We are investigating a mechanism that is essential for retroviruses, but still not sufficiently understood, which may also have broader implications for the regulation of cellular processes. In addition, the quality of the team, our strong collaboration with the NIH and Rockefeller University, and the use of modern methods that will allow us to track viral RNA in great detail also played a role. It was also important that the project has clear objectives and a realistic plan.<h5>How will this research contribute to the development of new treatments for retroviral infections?</h5>It is important to say that this is primarily basic research. Rather than developing a new drug directly, we are trying to understand, at the molecular level, the step that the virus cannot do without. Only when we fully understand the mechanism of these cellular processes and identify the essential factors for the export of unspliced ​​RNA and how they function, will we be able to better determine which interactions or mechanisms represent potentially vulnerable points. Similar mechanisms associated with the export of unspliced ​​mRNA also appear in some diseases, such as cancer, so I &nbsp;see the benefit of our research mainly in that it will refine our understanding of these pathological processes in the cell, and retroviruses help us do so. Therefore, our work on retroviruses not only shows us how the virus works, but also how the cell itself works.<h5>What responsibilities does your UCT Prague team have? How does the collaboration with your American partners work?</h5>At UCT Prague, we are conducting the project’s primary experimental work. Our research involves cell cultures, viral models, and various biochemical techniques ranging from immunochemistry to microscopy that allow us to track viral RNA and identify its cellular partners. In collaboration with colleagues from NIH, Frederick, we are developing single-particle tracking methods to observe viral RNA movement in living cells across both space and time. Furthermore, we are working with colleagues from Rockefeller University to employ iCLIP methods for the precise mapping of protein-binding sites on RNA. Both collaborations are valuable to us, because they are not just about data sharing, but also about the transfer of expertise and detailed know-how.<h5>Who else is collaborating on the project?</h5>At UCT Prague, we collaborate closely with the Department of Biotechnology and the Department of Biochemistry and Microbiology. Externally, we work with colleagues from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague) and the Central European Institute of Technology in Brno (CEITEC). Our research naturally necessitates the integration of diverse fields of expertise; it requires combining virology, cell biology, and biochemistry with advanced imaging and modern approaches to study RNA-protein interactions. This is exactly what makes our project capable of addressing complex questions that a single laboratory cannot tackle on its own.<h5>Are there plans to continue the project? Have you brought on new collaborators, and are you looking to welcome new colleagues to the team?</h5>Yes, definitely. In basic research, it often happens that one answered question opens up several more. High-quality, properly interpreted data provide a foundation you can build on — and that is what moves scientists forward. It is already clear that the topic of retroviral RNA export and packaging has broader implications and may reveal more general principles of how RNA functions within the cell. We also hope the project will be attractive to students, as it connects classical molecular biology, biochemistry, and virology with cutting-edge biotechnological methods. Students are already involved in the project as part of their bachelor’s and master’s theses.<h5>What was the personal turning point that motivated you to pursue a long-term investigation into retroviral particles?</h5>I first encountered retroviruses in the early 1990s during my diploma thesis, when I was working at IOCB Prague on HIV-1 protease inhibitors. At that time, AIDS could not yet be effectively treated, and retrovirus research had a completely different dimension. From the very beginning, I was fascinated by how such a relatively small and simple virus can outsmart evolutionarily highly optimized cellular processes and turn them to its own advantage. And that has never stopped fascinating me. From a scientific point of view, retroviruses are remarkable; just consider one of their enzymes, reverse transcriptase, without which no diagnostic or research laboratory in the world could function today. Without it, it would be impossible to diagnose RNA viruses like SARS-CoV-2, influenza, or HIV using RT-PCR tests, or, for example to produce recombinant human proteins in bacterial cells.

Tracking unspliced RNA: Professor Rumlová studies how retroviruses “hack” cells

News from LabRulezLCMS Library - Week 20, 2026

🎤Lindsay Repka&nbsp;Lindsay Repka is a chemistry professor at Middlebury College whose research explores photoredox chemistry, catalyst stability, and visible-light-driven transformations. Her lab emphasizes both mechanistic insight and hands-on student training in advanced analytical instrumentation.In this episode of Concentrating on Chromatography, we sit down with Lindsay Repka to discuss how LC-MS and GC-MS transformed her lab’s approach to photoredox chemistry.What began as a project to develop a visible-light photocrosslinking handle unexpectedly led to a major discovery: the solvent (DMF) was reacting with the photocatalyst itself. Using high-resolution LC-MS, Lindsay’s team observed multiple solvent adducts forming — sometimes with complete catalyst consumption. That discovery reshaped their research direction.This episode is a rare deep dive into both LC-MS and GC-MS within the same research project, showing how chromatography-driven insight can turn unexpected degradation into productive new reactivity.If you work in:<ul><li>Photoredox chemistry</li><li>Reaction optimization</li><li>Mass spectrometry method development</li><li>Catalyst screening</li><li>Academic synthetic chemistry</li></ul>…this conversation will resonate.<h4>Key Topics Covered</h4><ul><li>Photocatalyst stability in DMF, DCE, and MeCN</li><li>Demethylation under mild visible-light conditions</li><li>High-resolution Q-TOF LC-MS quantitation</li><li>Internal standard methodology in GC-MS</li><li>Signal-to-noise improvement using extracted ion chromatograms</li><li>Reaction reproducibility and quality control strategy</li></ul><h3>Video Transcription</h3>In this interview, Lindsay Repka discusses the role of photoredox chemistry in method development, photocrosslinking, solvent activation, catalyst stability, and the use of LC-MS and GC-MS to understand reaction pathways.<h4>What is photoredox chemistry?</h4>Photoredox chemistry uses light to activate a photocatalyst, which can either donate or accept an electron from a substrate. This generates radical species that can undergo new types of reactivity.Repka explains that one of the key advantages of photoredox chemistry is its ability to operate under mild conditions, often using visible light. This makes it attractive for sensitive molecules and biological systems, including potential applications in drug release, live-cell chemistry, and drug development.<h4>Photocrosslinking and drug-target interactions</h4>Repka’s group initially aimed to develop visible-light photocrosslinking methods to study drug interactions with biological targets. Photocrosslinking can covalently link a drug to its target, making it easier to identify the biological target of a compound.Traditional photocrosslinking often uses UV light, but visible light offers milder and more biologically compatible conditions.<h4>From photocrosslinking to solvent activation</h4>The project shifted direction when the desired photocrosslinking reactions gave very low yields. Instead of reacting with amino acids as intended, the radical intermediate mainly reacted with itself.The team explored different solvents to stabilize the radical, but found that some solvents, such as DMF, were not inert. Instead, the solvent reacted with the photocatalyst or radical species, revealing unexpected solvent activation chemistry.<h4>Why LC-MS was critical</h4>LC-MS became essential because the reaction mixtures were too complex and low-yielding for NMR or GC-MS. High-resolution LC-MS allowed the team to detect minor products, identify photocatalyst modifications, and observe solvent addition products with high confidence.Repka emphasizes that LC-MS was both a qualitative and quantitative tool. It was used quantitatively to measure how much photocatalyst remained after light exposure, and qualitatively to identify degradation products and new reactivity pathways.<h4>Photocatalyst stability workflow</h4>The team developed a systematic workflow to evaluate photocatalyst stability under light exposure. Because catalyst degradation was time-sensitive, reproducibility required strict control of experimental conditions.Key steps included using a glove box, commercial deoxygenated solvents, accurate weighing on a microbalance, controlled light exposure in a photoreactor, and temperature control with a chiller. These precautions helped reduce day-to-day variability and enabled reproducible measurements of catalyst remaining.<h4>Quantifying catalyst remaining by LC-MS</h4>Calibration curves were prepared using pure photocatalyst solutions and LC-MS ion areas. The team worked in the nanomolar range to maintain linearity.Instead of relying only on total ion chromatograms, they used extracted ion chromatograms (EICs) to improve signal-to-noise for the photocatalyst signal. Baseline subtraction was also applied to reduce noise and improve quantitation at low concentrations.Calibration curves and quality control samples were prepared and measured on the same day as the reaction samples, because LC-MS signal intensity can vary significantly from day to day.<h4>Why GC-MS was used later</h4>For demethylation studies, the group moved to GC-MS because the substrates and products were small and volatile enough for gas chromatography. GC-MS was better suited for rapidly screening many reaction conditions, including different photocatalysts, solvents, and oxidants.Instead of generating full calibration curves for every experiment, the team used an internal standard to streamline analysis and determine percent conversion based on relative response factors.<h4>Practical lessons from the project</h4>Repka highlights the importance of careful sample preparation, especially when working with very small quantities of photocatalysts. A high-quality microbalance, stable granite platform, antistatic tools, and aluminum weigh boats improved weighing accuracy and reproducibility.She also argues that mass spectrometry should be a standard part of photoredox method development because it can reveal minor products, support reaction optimization, and provide insights that may be difficult or impossible to obtain by NMR alone.<h4>Final perspective</h4>Beyond the chemistry, Repka emphasizes the importance of student training and mentoring. For her, research is not only about discovering new reactivity but also about giving students practical experience, helping them develop independence, and preparing them for future scientific careers.<blockquote>This text has been automatically transcribed from a video presentation using AI technology. It may contain inaccuracies and is not guaranteed to be 100% correct.</blockquote><blockquote><h4>Concentrating on Chromatography Podcast</h4>Dive into the frontiers of chromatography, mass spectrometry, and sample preparation with host David Oliva. Each episode features candid conversations with leading researchers, industry innovators, and passionate scientists who are shaping the future of analytical chemistry. From decoding PFAS detection challenges to exploring the latest in AI-assisted liquid chromatography, this show uncovers practical workflows, sustainability breakthroughs, and the real-world impact of separation science. Whether you’re a chromatographer, lab professional, or researcher you'll discover inspiring content!You can find Concentrating on Chromatography Podcast in podcast apps:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://open.spotify.com/show/1wZg67rCjoGju4yhqxI3tL">Spotify</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podcasts.apple.com/tz/podcast/concentrating-on-chromatography/id1788429185">Apple podcast</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podscan.fm/podcasts/concentrating-on-chromatography">podscan</a></li></ul>and on <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/@ChromatographyTalk/videos">YouTube channel</a></blockquote>

Using LC-MS & GC-MS to Decode Photoredox Catalyst Stability

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The Right Laboratory Balance Service at the Right Time
Event Program:
<ul>
<li>Selection of the right instrument for your application</li>
<li>Installation and qualification</li>
<li>Preventive maintenance</li>
<li>Calibration</li>
<li>Routine testing</li>
<li>Replacement</li>
</ul>
Weighing is a core process in almost every application in a lab. To maintain consistent results, it&#39;s essential to regularly service your equipment. But what are the most important services, and how often do they need to be performed?
In this webinar, we will guide you, based on the lifecycle of a balance, through the different services that can help you to keep your instrument accurate and extend its lifetime – from the instrument selection to its installation, throughout its routine operation, and up to the time for replacement.
Join our live webinar with METTLER TOLEDO experts to gain a better understanding.
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Presenter: Simona Venzin (Head of Service Product Management, METTLER TOLEDO)
</blockquote>
<blockquote>
Presenter: Walter Krebs (Head of GWP Product Management, METTLER TOLEDO)
</blockquote>

Mettler-Toledo: Service Balances the Smart Way

Service Balances the Smart Way

A guide through different services that can help you to keep your instrument accurate and extend its lifetime.

In this training session, the METTLER TOLEDO product managers will address the questions that are most commonly asked in the field. They will talk about weight handling, maintenance of mass comparators, selection of products, elevation dependence of measurements, and many more topics. Additionally, you will have the opportunity to ask your own questions in an open Q&amp;A session at the end.
Key Takeaways
This is a great opportunity for all mass metrologists, as those questions that many others ask might also be of relevance to you. 
Program
<ul>
<li>Discover answers to the most frequently asked questions in mass metrology
</li>
<li>Learn more about weight handling, mass comparator maintenance, etc.
</li>
<li>Ask our experts your own questions
</li>
</ul>
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Speaker: Dr. Frederik Eiler (METTLER TOLEDO, Product Manager Metrology Solutions)
</blockquote>
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Speaker: Mark Kliebenschädel (METTLER TOLEDO, Product Manager Metrology Solutions)
</blockquote>

Mettler-Toledo: Mass Calibration – Most Frequently Asked Questions

Mass Calibration – Most Frequently Asked Questions

Opportunity for all mass metrologists, as those questions that many others ask might also be of relevance to you.

Event Program
<ul>
<li>Discover the fundamentals of multiparameter analysis and its role in increasing the productivity.</li>
<li>Explore real-world applications in pharmaceuticals, food &amp; beverage, and water testing.</li>
<li>Learn how automation in electrochemistry revolutionizes efficiency and empowers sustainable practices.</li>
<li>Gain insights into navigating compliance regulations seamlessly with METTLER TOLEDO&#39;s products and services.</li>
</ul>
In today&#39;s world, maximizing productivity is no longer optional. Across industries, there&#39;s a growing need for efficient and reliable methods to evaluate and optimize solutions. This is where multiparameter analysis emerges as a promising tool.
Precise pH measurement plays a crucial role in various sustainability initiatives. From ensuring optimal growth conditions in biofuel production to maintaining safe drinking water quality, pH data is essential. METTLER TOLEDO pH meters offer exceptional accuracy and reliability, making them an indispensable tool for reliable data in your sustainability journey.
The true strength of these meters also lies in their ability to seamlessly connect with other instruments for measuring critical parameters like refractive index, density, spectroscopic data etc. This enables analysis of a wider range of parameters simultaneously or in parallel. This comprehensive approach provides a holistic view of the samples, empowering one to optimize resource utilization, ensure product quality and safety, and develop sustainable solutions. By combining pH with other key parameters as mentioned above, deeper insights can also be obtained to minimize waste, maximize efficiency, and guarantee consistent product quality that adheres to safety regulations – all crucial aspects of sustainable practices.
This webinar, led by Dr. Reena Mascarenhas, Assistant Manager of Market Development, will explore multiparameter analysis and its role in streamlining the processes across various industries.
Join us for a Live Webinar on Multiparameter Analysis for Sustainable Solutions!
Register now and secure your spot!
For multiparameter analysis, what instruments can a pH meter be connected to?
Beyond parameters like conductivity, DO, ISE, and Redox, which can be measured by the same meter, a pH meter can be connected to other instruments like a refractometer, density meter, UV/VIS spectrometer, titrator, and balance.
In which industries can quality control labs leverage multiparameter analysis to improve their processes?
Multiparameter analysis empowers quality control labs across various industries. In the pharmaceutical sector, labs can ensure consistent drug quality by simultaneously measuring parameters like pH, conductivity, and concentration. The food and beverage industry, including the wine industry, benefits by monitoring key parameters like pH, conductivity, density, and dissolved oxygen to guarantee consistent taste, texture, and shelf life. It also plays a crucial role in monitoring safe drinking water (concentration of ions, pH, conductivity) and optimizing agricultural soil conditions (pH, conductivity, nutrient levels). By measuring multiple parameters simultaneously, labs achieve efficiency and ensure high-quality products across diverse industries.
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Presenter: Dr Reena Mascarenhas
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<blockquote>
Reena is an electrochemist, working for METTLER TOLEDO, with over five years of experience in training others in various aspects of the field. Her in-depth understanding, technical expertise, and engaging and informative training style make her a prominent speaker for this webinar.
</blockquote>

Mettler-Toledo: Multiparameter Analysis for the Lab: from Complexity to Simplicity

Multiparameter Analysis for the Lab: from Complexity to Simplicity

A Live Webinar for Optimizing Workflows for pH, Refractometry, and Density Determination.

Multiparameter Analysis for the Laboratories

Data management and manual transcription of critical process data remain one of the major challenges and potential sources of errors in the analytical laboratory.
As a lot of the laboratory processes evolve around sample preparation for HPLC or GC, with crucial weighing and preparative steps, this webinar aims to showcase some seamless data management and transfer solutions, from balance to LC. The LabX™ balance software and OpenLab CDS platform can enable various levels of integrated data management, while also improving productivity and offering a high degree of data integrity.
Join the METTLER TOLEDO and Agilent teams for a webinar to understand how you can support digitalized and scalable sample preparation processes for better chromatography results. 
Program Overview
<ul>
<li>Introduction to the digital lab
</li>
<li>Improving analytical sample preparation workflows
</li>
<li>Live demonstration of seamless data transfer options
</li>
<li>Q&amp;A with presenters
</li>
</ul>
<blockquote>
Presenter: Andrea Brütsch (Head Business Development Initiatives)
</blockquote>
<blockquote>
Presenter: Kevin Koelliker (Agilent Technologies, Application Engineer)
</blockquote>

Mettler Toledo: Automated Data Management for LC/GC Workflows

Automated Data Management for LC/GC Workflows

How can you support digitalized and scalable sample preparation processes for better chromatography results.

In today’s fast-paced research environment, optimizing lab workflows is crucial to maintaining productivity and ensuring high-quality results. Sample preparation is a critical step in chromatography and mass spectrometry, yet it often involves time-consuming and error-prone manual processes.Join us for an exclusive webinar with Dr. Jens Lättig, Senior Scientist at Tecan and Dr. Cassandra Rusher, European Technical Support Specialist at Eprep, where they’ll reveal how the Resolvex® Prep revolutionizes sample preparation for chromatography and mass spectrometry.Key learning objectives:<ul><li>Slash prep time: Discover how you can reduce your setup to just 5–15 minutes, freeing you to focus on critical tasks while Resolvex® Prep works autonomously.</li><li>Enhance accuracy: Learn how analytical syringes and specialized tools deliver consistent, reliable results – minimizing human error.</li><li>Achieve consistency: Find out how you can achieve repeatable results across various sample types and workflows, streamlining your processes.</li><li>Unlock versatility: Explore Resolvex® Prep’s built-in wash station, RFID deck scan, and seamless sample transfer, all designed to meet your research needs.</li></ul>Who should attend?<ul><li>Laboratory scientists and managers from analytical laboratories in: pharma, biopharma, biotech, the food industry, the environmental sector, agriculture, drug screening, proteomics, and metabolomics.</li></ul>Certificate of attendanceAll webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.<blockquote>Presenter: Jens Lattig, PhD (Sales Development Manager Proteomics &amp; MS Sample Prep, Tecan)Dr. Jens Lättig is a Sales Development Manager Proteomics &amp; MS Sample Preparation at Tecan. He has a PhD in biochemistry, and has worked in drug research projects in Germany and France. At Tecan, he is responsible for the Resolvex™ instruments and consumables portfolio in Europe.Presenter: Cassandra Rusher, PhD (European Technical Support Specialist, Eprep)Dr. Cassandra Rusher is a technical support specialist for the Resolvex Prep. at Eprep. She has a PhD in chemistry and a background specializing in chromatography including sample preparation. Her previous roles have included technical support and product management in the analytical chromatography sector. Her focus now is on supporting the automation of sample preparation methods across a range of industries that are utilizing analytical chromatography techniques.Moderator: Carrie Haslam (Associate Editor, SelectScience)</blockquote>

SelectScience: Efficient sample prep for expert mass spectrometry and chromatography

Efficient sample prep for expert mass spectrometry and chromatography

Join us for a webinar where we will reveal how the Resolvex® Prep revolutionizes sample preparation for chromatography and mass spectrometry.

Efficient sample prep for MS and chromatography

This webinar explains what calibration and qualification of weighing instruments are and why these related concepts are important for Good Manufacturing Practice. It also shows how to seamlessly incorporate these important concepts into a weighing process to ensure both weighing accuracy and product quality.In the highly regulated pharmaceutical and medical device industries, even the smallest inconsistencies can lead to serious product issues. As weighing instruments and applications are present in almost every stage of a manufacturing workflow, they can strongly influence the quality and integrity of the final product.Good Manufacturing Practice or GMP is a regulation that is applicable to any pharmaceutical production process. It ensures that pharmaceutical products are consistently produced and controlled according to quality standards.Weighing according to GMP requirementsIn many countries, GMP has been integrated into national laws that must be followed by pharmaceutical manufacturers.Program:&nbsp;<ul><li>What GMP is and why it is important in weighing</li><li>How to apply GMP requirements to your processes</li><li>What calibration and qualification of weighing instruments are</li><li>How equipment qualification is done in a way that satisfies GMP requirements</li><li>How METTLER TOLEDO can support you in getting weighing calibration and qualification under control</li></ul><blockquote>Speaker: Walter Krebs (Good Weighing Practice, METTLER TOLEDO)</blockquote>

Mettler Toledo: Calibration and Qualification in Accordance with GMP Requirements

Calibration and Qualification in Accordance with GMP Requirements 

What calibration and qualification of weighing instruments are and why these related concepts are important for Good Manufacturing Practice

Calibration and Qualification in Accordance with GMP

Laboratory balance cleaning is extremely important for accurate weighing results and operator safety. It can be challenging but also fast and easy if you know how to do it right.A clean analytical balance or precision balance is the first step toward safe and accurate weighing. Cleaning increases user safety reduces the risk of cross-contamination, and is the most important action to prolong instrument life. Join our free live webinar to find out more about the benefits of and solutions for cleaning your balance.Program:<ul><li>Why cleaning lab equipment is important for safety and weighing accuracy</li><li>The consequences of not cleaning your balances correctly</li><li>How often you should clean your balance</li><li>The detergents that are suitable for balance cleaning</li><li>The balance features that support fast and effortless cleaning</li></ul><blockquote>Presenter: Adriano Guiso (Trainer, METTLER TOLEDO)</blockquote>

Mettler Toledo: Laboratory Balance Cleaning

Laboratory Balance Cleaning

Join our free live webinar to find out more about the benefits of and solutions for cleaning your balance.

Balances and scales play a critical role in research and development, quality assurance, and production. Errors in weighing cost time and money, due to rework, waste, and product recalls.In order to maintain consistent product quality and comply with standards and regulations, the performance of balances and scales needs to be verified regularly with a calibration. Routine testing of balances or scales in-between these scheduled calibrations helps to maintain accuracy by ensuring early detection of non-conformance with weighing process requirements so that corrective action can be taken in a timely manner.This webinar will give you a good understanding of why balance and scale testing is crucial for the accuracy of your weighing results in laboratory and production environments. We explain what your routine testing plan must contain, and, on top of that, we offer an overview of how to perform these routine tests correctly.&nbsp;Program<ul><li>What routine testing is</li><li>The difference between routine testing, calibration, and adjustment</li><li>The consequences of not testing a balance or scale</li><li>The four pillars of routine testing</li><li>Good Weighing Practice™ (GWP®)</li></ul><blockquote>Presenter: Walter Krebs (Good Weighing Practice™, METTLER TOLEDO)</blockquote>

Mettler Toledo: Routine Testing of Balances and Scales 

Routine Testing of Balances and Scales 

Why balance and scale testing is crucial for the accuracy of your weighing results in laboratory and production environments

Whilst plastics are thought to be essential in laboratory and biomanufacturing processes due to their reliability, they generate significant waste and contribute to carbon footprints. As a result, laboratories are now considering the environmental impact plastics cause and are seeking alternative solutions.Plant-based materials provide a greener alternative, and in the case of replacing plastic-based resins, plant-based solutions have been shown to maintain the same consistency with the added bonus of reducing green house emissions.In this SelectScience webinar, hear from Thermo Fisher Scientific experts, Dr. Colin Wright, Staff Scientist, R&amp;D and Dr. Sune Lund Sporring, Sr. Manager R&amp;D, as they share insights on using traditional plastic-based resins compared with plant-based, focusing directly on the impact on the mass balance approach. The accreditation of these biobased films with the International Sustainability and Carbon Certification (ISCC) Plus certification will also be covered, showcasing how the need for laboratories to validate these biofilms can be removed, accelerating implementation.<h5>Key learning objectives:</h5><ul><li>Understand the basic of resins and sustainability</li><li>Learn about the role of biobased resins in sustainability</li><li>Explore Thermo Fisher Scientific’s Greener by Design initiative</li><li>Identify practical steps for laboratories to reduce environmental impact</li></ul><h5>Who should attend?</h5><ul><li>Lab technicians, scientists and researchers in the pharma and biopharma industries as well as academia</li></ul><h5>Certificate of attendance</h5>All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.<blockquote>Presenter: Dr. Colin Wright (Staff Scientist, R&amp;D, Thermo Fisher Scientific)Dr. Colin Wright holds a Ph.D. in Polymer Science from the University of Akron, with a robust background in polymer synthesis, characterization, and a keen interest in sustainability. During his graduate research, he focused on the modification of poly(lactic acid) to enhance the polymer's post-polymerization functionality. Prior to joining Thermo Fisher Scientific in 2020, he was a teacher in academia. Since joining Thermo Fisher, he has been integral to the resins and sustainability teams, working on developing innovative solutions that align with the company's commitment to environmental responsibility Presenter: Dr. Sune Lund Sporring (Sr. Manager R&amp;D, Thermo Fisher Scientific)Dr. Sune Lund Sporring holds an MSc in Chemistry (2001) and a Ph.D. in Clinical Medicine from the University of Copenhagen. His expertise spans chemistry, polymers, materials, irradiation, clinical medicine, and surface modifications. He co-founded two spin-out companies from the University of Copenhagen, focusing on implant development and material interactions with the human body. &nbsp;Since joining Thermo Fisher Scientific in 2017, he has led a team of researchers in the bioscience field, innovating solutions to meet customer needs. He is also actively involved in Thermo Fisher Scientific's sustainability efforts, demonstrating his commitment to environmental responsibility. &nbsp;Moderator: &nbsp;Olivia Long (Editorial Team, SelectScience)</blockquote>

SelectScience: Reducing the environmental impact of lab plastics with plant-based solutions

Reducing the environmental impact of lab plastics with plant-based solutions

In this webinar, hear from Thermo Fisher Scientific experts, as they share insights on using traditional plastic-based resins compared with plant-based,

Reducing the environmental impact of lab plastics

<h4>Safety isn’t optional — it’s foundational.</h4>At Agilent, Safer Labs is more than an initiative — it’s our commitment to fostering safer, healthier, and more productive laboratory environments. Safety should be the most important criterion in every workplace, yet the understanding and implementation of safety practices often vary across individuals and teams.To build a uniform, strong, and informed safety culture, we invite you to join our upcoming Safer Labs Webinar, designed for lab professionals who are committed to elevating safety standards in their organizations.<h5>What to Expect:</h5>In this session, our experts will shed light on key EHS concerns that impact daily lab operations, including:<ul><li>Safe Handling</li><li>Safe Storage</li><li>Safe Instrumentation</li><li>Safe Usage</li><li>Safe Transportation</li><li>Safe Disposal</li></ul>You’ll gain actionable insights, practical guidance, and a deeper understanding of how the right practices — supported by the right tools — can dramatically reduce risks and enhance overall lab efficiency.Agilent solutions are engineered with rigorous safety parameters, ensuring our customers and their laboratories are protected, supported, and empowered to perform at their best.<h5>Who Should Attend?</h5><ul><li>EHS Managers</li><li>Chemists</li><li>QC Teams</li><li>R&amp;D Scientists</li><li>Professionals from Pharma, Biopharma, Food &amp; Beverage, and</li><li>Environmental Analytical Testing Labs</li></ul><h5>Why You Shouldn’t Miss This:</h5><ul><li>Be part of a growing movement to build safer workplaces across industries.</li><li>Let’s work together to create laboratories where safety is a shared responsibility and a consistent practice, ensuring long‑term well‑being and operational excellence.</li></ul><blockquote>Presenter: Dr. Sunil B Lakhmapure (Pre-Sales Application Engineer, Agilent Technologies)Sunil holds 19 year plus experience in the analytical field with major exposure to LC/GC with Single Quad, Triple Quad and high resolution (QToF) mass spectroscopy. Started career in Pharma R&amp;D as a scientist with hands on experience on high end instruments like LC/MS, XRD &amp; NMR. Developed &amp; published application notes using Chromatographic techniques on real world samples/issues at various levels.</blockquote>

Agilent Technologies: The Journey of Safer Science through Safer Labs

The Journey of Safer Science through Safer Labs

Agilent Safer Labs webinar covers lab safety practices, EHS risks, and solutions for safer and more efficient laboratory operations.

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