LCMS
More information
WebinarsAbout usContact usTerms of use
LabRulez s.r.o. All rights reserved. Content available under a CC BY-SA 4.0 Attribution-ShareAlike
Author
Watrex Praha
Watrex Praha
WATREX Prague is the distributor and producer of HPLC techniques in the Czech Republic and Slovakia. Main Chromatografic and Related Techniques Supported: LC, GPC, IC, IEC, Automated SPE, LC Columns and special column packings, LC method development, Software development, Laboratory Robots.
Tags
Article
Product
LinkedIn Logo

Selection of a Water Purification System for the Laboratory: Key Factors and Recommendations

Th, 10.4.2025
| Original article from: Watrex Praha
In a laboratory environment, water quality plays a crucial role in conducting analytical methods, preparing chemical solutions, and ensuring the accuracy and reproducibility of experiments.
<p><strong>Watrex: </strong>Selection of a Water Purification System for the Laboratory: Key Factors and Recommendations</p>

Watrex: Selection of a Water Purification System for the Laboratory: Key Factors and Recommendations

In a laboratory environment, water quality plays a crucial role in conducting analytical methods, preparing chemical solutions, and ensuring the accuracy and reproducibility of experiments. Even minimal contamination can negatively impact analytical results, making it essential to ensure an appropriate level of water purity. 

Modern laboratory applications require different levels of water purification depending on the specific process requirements, and the choice of a suitable system depends on several factors, including the quality of the feed water, the required purity, the technological solution, and operational costs. This article focuses on the key aspects to consider when selecting a laboratory water purification system.

Required Water Quality 

When selecting a water purification system, it is essential to determine the required water quality according to its intended use: 

  • Type I (ultrapure water) – suitable for sensitive analytical methods such as HPLC, ICP-MS, or PCR. 
  • Type II (pure water) – used for buffer preparation, culture media, or clinical applications. 
  • Type III (technical water) – suitable for washing laboratory glassware, autoclaves, or other technical applications. 

View the Watrex Praha Water System Catalog. 

Feed Water Quality 

Before selecting a system, it is advisable to analyze the feed water, which may come from the municipal water supply or pre-treated sources, to allow the supplier to recommend the most suitable system for your needs. Parameters such as ion content, organic substances, and microbial contamination can influence the suitability of a specific system. 

Purification Technologies 

Modern water purification systems combine several technologies to achieve the required purity: 

  • Filtration – mechanical filtration is the first step in the purification process, removing solid particles such as sediments, rust, and other mechanical impurities. Filters with different pore sizes (e.g., 5 μm or 0.2 μm) are used depending on the required water purity. 
  • Activated Carbon – this step removes chlorine, organic contaminants, and certain volatile organic compounds (VOCs). Activated carbon absorbs chemicals that could affect analytical methods or cause unwanted reactions. 
  • Reverse Osmosis (RO) – one of the most effective methods for removing dissolved salts, heavy metals, bacteria, and most organic impurities. This technology uses a semi-permeable membrane that allows water to pass through while retaining most contaminants, significantly reducing water conductivity. 

Watrex img.2: Reverse osmosis filter connection scheme.Watrex img.2: Reverse osmosis filter connection scheme.

  • Deionization (DI) – this method uses ion exchange resins to replace cations (e.g., Ca²⁺, Mg²⁺, Na⁺) and anions (e.g., Cl⁻, SO₄²⁻) with hydrogen (H⁺) and hydroxide (OH⁻) ions, resulting in nearly ion-free water. This technology is essential for producing ultrapure water. 
  • Ultraviolet (UV) Radiation – used for water disinfection and organic matter breakdown. UV radiation at a wavelength of 185 nm effectively reduces total organic carbon (TOC) content, while UV at 254 nm is used for bacterial and viral inactivation. 
  • Ultrafiltration (UF) – this technology utilizes membranes with pore sizes smaller than 0.01 μm, effectively removing bacteria, endotoxins, pyrogens, and other biological contaminants. It is essential in applications requiring the elimination of biological contamination, such as buffer preparation for cell cultures. 
  • Electrodeionization (EDI) – an advanced technology combining ion exchange resins with an electrochemical regenerator, enabling continuous operation without chemical regeneration. The result is water with exceptionally low conductivity and minimal contamination. 

Watrex img.3: Types of purification technologies.Watrex img.3: Types of purification technologies.

The choice of the right combination of these technologies depends on the required water purity and its laboratory application. 

Capacity and Flow Rate 

The system selection should match the laboratory's daily water consumption. For example, small laboratories may require 10–50 L/day, while large research facilities may need hundreds of liters per day. The system's flow rate should be sufficient for efficient operation and rapid container filling. 

Maintenance, Service, and Supplier Selection 

When selecting a system, it is important to consider operating costs, including filter replacement, resin exchange, and other components. Regular maintenance is essential for maintaining optimal functionality and water quality. 

In addition to technical parameters, the availability of spare parts and manufacturer service support should also be considered. Reputable suppliers typically offer warranty and post-warranty service, which is crucial for the long-term reliability of the system. Thanks to its own service team, Watrex Praha provides all needs from maintenance and service to the availability of all necessary spare parts and filters for its own water systems or HealForce brand water systems.

Conclusion 

The selection of a laboratory water purification system should be carefully considered based on the specific requirements of the workplace. Key factors include the required water purity, feed water parameters, purification technologies, capacity, operating costs, and service availability. Investing in the right system ensures optimal conditions for laboratory experiments and the protection of sensitive analytical methods. At Watrex Praha, we are fully available to assist you in selecting the best solution for your needs! Contact us at [email protected] or visit our website at www.watrex.com.

Watrex Praha
LinkedIn Logo
 

Related content

Analysis of Anti-Degradant Additive (6PPD) and its Transformation Product 6PPD-Quinone in Tire Rubber Using an Integrated HPLC System

Applications
| 2026 | Shimadzu
Instrumentation
HPLC
Manufacturer
Shimadzu
Industries
Energy & Chemicals

Performance Evaluation of Microbial Identification Using a Benchtop MALDI-TOF MS

Applications
| 2026 | Shimadzu
Instrumentation
MALDI, LC/MS, LC/TOF, Software
Manufacturer
Shimadzu
Industries
Pharma & Biopharma, Food & Agriculture

A Combined Method for Anionic, Cationic, and Zwitterionic PFAS using a Direct Injection UPLC™-MS/MS Method for Environmental Water Samples

Applications
| 2026 | Waters
Instrumentation
LC/MS, LC/MS/MS, LC/QQQ
Manufacturer
Waters
Industries
Environmental

Beyond the box: A ready-to-run workflow for quantitating 80 drugs of abuse in whole blood with the TSQ Certis Triple Quadrupole MS

Applications
| 2026 | Thermo Fisher Scientific
Instrumentation
LC/MS, LC/MS/MS, LC/QQQ
Manufacturer
Thermo Fisher Scientific
Industries
Forensics

Mastering Single Cell Proteomics: Daily Excellence with μPAC Neo Plus Trap-and-Elute Workflow

Presentations
| 2026 | Thermo Fisher Scientific
Instrumentation
HPLC, LC/Orbitrap, LC/MS, LC/MS/MS
Manufacturer
Thermo Fisher Scientific
Industries
Proteomics
 

Related articles

The Effect of Needle Gauge and Flow Rate on Evaporation Rate
Article | Science and research

The Effect of Needle Gauge and Flow Rate on Evaporation Rate

The study evaluates how needle gauge, nitrogen flow rate, and needle design influence solvent evaporation rate during sample concentration and provides practical optimization guidance.
Organomation
tag
share
more
News from LabRulezLCMS Library - Week 11, 2026
Article | Application

News from LabRulezLCMS Library - Week 11, 2026

This week we bring you application notes by Agilent Technologies, KNAUER, Shimadzu and Waters Corporation and technical note by Thermo Fisher Scientific!
LabRulez
tag
share
more
CATRIN researchers offer a “greener” way to make supercapacitors
Article | Science and research

CATRIN researchers offer a “greener” way to make supercapacitors

CATRIN scientists show that green solvents Cyrene and Tamisolve can replace toxic NMP in supercapacitor production while maintaining high electrochemical performance and enabling more sustainable manufacturing.
CATRIN
tag
share
more
Teaching Separation Science in High School
Interview | Scientists

Teaching Separation Science in High School

This interview explores how high school students learn separation science through filtration, gravimetric analysis, and chromatography, building the foundations for future chemistry studies.
Organomation
tag
share
more
 

Related content

Analysis of Anti-Degradant Additive (6PPD) and its Transformation Product 6PPD-Quinone in Tire Rubber Using an Integrated HPLC System

Applications
| 2026 | Shimadzu
Instrumentation
HPLC
Manufacturer
Shimadzu
Industries
Energy & Chemicals

Performance Evaluation of Microbial Identification Using a Benchtop MALDI-TOF MS

Applications
| 2026 | Shimadzu
Instrumentation
MALDI, LC/MS, LC/TOF, Software
Manufacturer
Shimadzu
Industries
Pharma & Biopharma, Food & Agriculture

A Combined Method for Anionic, Cationic, and Zwitterionic PFAS using a Direct Injection UPLC™-MS/MS Method for Environmental Water Samples

Applications
| 2026 | Waters
Instrumentation
LC/MS, LC/MS/MS, LC/QQQ
Manufacturer
Waters
Industries
Environmental

Beyond the box: A ready-to-run workflow for quantitating 80 drugs of abuse in whole blood with the TSQ Certis Triple Quadrupole MS

Applications
| 2026 | Thermo Fisher Scientific
Instrumentation
LC/MS, LC/MS/MS, LC/QQQ
Manufacturer
Thermo Fisher Scientific
Industries
Forensics

Mastering Single Cell Proteomics: Daily Excellence with μPAC Neo Plus Trap-and-Elute Workflow

Presentations
| 2026 | Thermo Fisher Scientific
Instrumentation
HPLC, LC/Orbitrap, LC/MS, LC/MS/MS
Manufacturer
Thermo Fisher Scientific
Industries
Proteomics
 

Related articles

The Effect of Needle Gauge and Flow Rate on Evaporation Rate
Article | Science and research

The Effect of Needle Gauge and Flow Rate on Evaporation Rate

The study evaluates how needle gauge, nitrogen flow rate, and needle design influence solvent evaporation rate during sample concentration and provides practical optimization guidance.
Organomation
tag
share
more
News from LabRulezLCMS Library - Week 11, 2026
Article | Application

News from LabRulezLCMS Library - Week 11, 2026

This week we bring you application notes by Agilent Technologies, KNAUER, Shimadzu and Waters Corporation and technical note by Thermo Fisher Scientific!
LabRulez
tag
share
more
CATRIN researchers offer a “greener” way to make supercapacitors
Article | Science and research

CATRIN researchers offer a “greener” way to make supercapacitors

CATRIN scientists show that green solvents Cyrene and Tamisolve can replace toxic NMP in supercapacitor production while maintaining high electrochemical performance and enabling more sustainable manufacturing.
CATRIN
tag
share
more
Teaching Separation Science in High School
Interview | Scientists

Teaching Separation Science in High School

This interview explores how high school students learn separation science through filtration, gravimetric analysis, and chromatography, building the foundations for future chemistry studies.
Organomation
tag
share
more
 

Related content

Analysis of Anti-Degradant Additive (6PPD) and its Transformation Product 6PPD-Quinone in Tire Rubber Using an Integrated HPLC System

Applications
| 2026 | Shimadzu
Instrumentation
HPLC
Manufacturer
Shimadzu
Industries
Energy & Chemicals

Performance Evaluation of Microbial Identification Using a Benchtop MALDI-TOF MS

Applications
| 2026 | Shimadzu
Instrumentation
MALDI, LC/MS, LC/TOF, Software
Manufacturer
Shimadzu
Industries
Pharma & Biopharma, Food & Agriculture

A Combined Method for Anionic, Cationic, and Zwitterionic PFAS using a Direct Injection UPLC™-MS/MS Method for Environmental Water Samples

Applications
| 2026 | Waters
Instrumentation
LC/MS, LC/MS/MS, LC/QQQ
Manufacturer
Waters
Industries
Environmental

Beyond the box: A ready-to-run workflow for quantitating 80 drugs of abuse in whole blood with the TSQ Certis Triple Quadrupole MS

Applications
| 2026 | Thermo Fisher Scientific
Instrumentation
LC/MS, LC/MS/MS, LC/QQQ
Manufacturer
Thermo Fisher Scientific
Industries
Forensics

Mastering Single Cell Proteomics: Daily Excellence with μPAC Neo Plus Trap-and-Elute Workflow

Presentations
| 2026 | Thermo Fisher Scientific
Instrumentation
HPLC, LC/Orbitrap, LC/MS, LC/MS/MS
Manufacturer
Thermo Fisher Scientific
Industries
Proteomics
 

Related articles

The Effect of Needle Gauge and Flow Rate on Evaporation Rate
Article | Science and research

The Effect of Needle Gauge and Flow Rate on Evaporation Rate

The study evaluates how needle gauge, nitrogen flow rate, and needle design influence solvent evaporation rate during sample concentration and provides practical optimization guidance.
Organomation
tag
share
more
News from LabRulezLCMS Library - Week 11, 2026
Article | Application

News from LabRulezLCMS Library - Week 11, 2026

This week we bring you application notes by Agilent Technologies, KNAUER, Shimadzu and Waters Corporation and technical note by Thermo Fisher Scientific!
LabRulez
tag
share
more
CATRIN researchers offer a “greener” way to make supercapacitors
Article | Science and research

CATRIN researchers offer a “greener” way to make supercapacitors

CATRIN scientists show that green solvents Cyrene and Tamisolve can replace toxic NMP in supercapacitor production while maintaining high electrochemical performance and enabling more sustainable manufacturing.
CATRIN
tag
share
more
Teaching Separation Science in High School
Interview | Scientists

Teaching Separation Science in High School

This interview explores how high school students learn separation science through filtration, gravimetric analysis, and chromatography, building the foundations for future chemistry studies.
Organomation
tag
share
more
 

Related content

Analysis of Anti-Degradant Additive (6PPD) and its Transformation Product 6PPD-Quinone in Tire Rubber Using an Integrated HPLC System

Applications
| 2026 | Shimadzu
Instrumentation
HPLC
Manufacturer
Shimadzu
Industries
Energy & Chemicals

Performance Evaluation of Microbial Identification Using a Benchtop MALDI-TOF MS

Applications
| 2026 | Shimadzu
Instrumentation
MALDI, LC/MS, LC/TOF, Software
Manufacturer
Shimadzu
Industries
Pharma & Biopharma, Food & Agriculture

A Combined Method for Anionic, Cationic, and Zwitterionic PFAS using a Direct Injection UPLC™-MS/MS Method for Environmental Water Samples

Applications
| 2026 | Waters
Instrumentation
LC/MS, LC/MS/MS, LC/QQQ
Manufacturer
Waters
Industries
Environmental

Beyond the box: A ready-to-run workflow for quantitating 80 drugs of abuse in whole blood with the TSQ Certis Triple Quadrupole MS

Applications
| 2026 | Thermo Fisher Scientific
Instrumentation
LC/MS, LC/MS/MS, LC/QQQ
Manufacturer
Thermo Fisher Scientific
Industries
Forensics

Mastering Single Cell Proteomics: Daily Excellence with μPAC Neo Plus Trap-and-Elute Workflow

Presentations
| 2026 | Thermo Fisher Scientific
Instrumentation
HPLC, LC/Orbitrap, LC/MS, LC/MS/MS
Manufacturer
Thermo Fisher Scientific
Industries
Proteomics
 

Related articles

The Effect of Needle Gauge and Flow Rate on Evaporation Rate
Article | Science and research

The Effect of Needle Gauge and Flow Rate on Evaporation Rate

The study evaluates how needle gauge, nitrogen flow rate, and needle design influence solvent evaporation rate during sample concentration and provides practical optimization guidance.
Organomation
tag
share
more
News from LabRulezLCMS Library - Week 11, 2026
Article | Application

News from LabRulezLCMS Library - Week 11, 2026

This week we bring you application notes by Agilent Technologies, KNAUER, Shimadzu and Waters Corporation and technical note by Thermo Fisher Scientific!
LabRulez
tag
share
more
CATRIN researchers offer a “greener” way to make supercapacitors
Article | Science and research

CATRIN researchers offer a “greener” way to make supercapacitors

CATRIN scientists show that green solvents Cyrene and Tamisolve can replace toxic NMP in supercapacitor production while maintaining high electrochemical performance and enabling more sustainable manufacturing.
CATRIN
tag
share
more
Teaching Separation Science in High School
Interview | Scientists

Teaching Separation Science in High School

This interview explores how high school students learn separation science through filtration, gravimetric analysis, and chromatography, building the foundations for future chemistry studies.
Organomation
tag
share
more
Other projects
GCMS
ICPMS
Follow us
FacebookX (Twitter)LinkedInYouTube
More information
WebinarsAbout usContact usTerms of use
LabRulez s.r.o. All rights reserved. Content available under a CC BY-SA 4.0 Attribution-ShareAlike