LCMS
More information
WebinarsAbout usContact usTerms of use
LabRulez s.r.o. All rights reserved. Content available under a CC BY-SA 4.0 Attribution-ShareAlike
Author
Organomation
Organomation
Organomation, founded in 1959, designs and manufactures high-quality nitrogen evaporators and extraction systems. Known for innovation and durability, their lab instruments are used globally for efficient sample preparation with strong customer support.
Tags
Article
Product
Video
LinkedIn Logo

Am I Paying Too Much for my Nitrogen Gas Cylinders?

Th, 19.6.2025
| Original article from: Organomation
Nitrogen cylinders come with hidden costs—rentals, refills, delivery, and waste. A nitrogen generator offers a safer, cheaper, and more efficient long-term solution.
Video placeholder
  • Photo: Organomation: Am I Paying Too Much for my Nitrogen Gas Cylinders?
  • Video: Organomation: NITRO-GEN+ Nitrogen Generator for LCMS Demonstration 

How Does Your Monthly Nitrogen Gas Bill Compared to Other Labs?

If your lab relies on nitrogen gas cylinders, you already know how quickly costs can add up. Between purchase prices, rental fees, delivery charges, and frequent refills, nitrogen cylinders can become a hidden financial drain on your operations.

But how do you know if you're paying a fair price—or if you're overspending compared to other labs? Our "Am I Overpaying on my Nitrogen Gas Cylinders?" tool helps you determine whether your current nitrogen supply costs are within an acceptable range or if you're paying too much.

The Hidden Costs of Nitrogen Cylinders

Nitrogen cylinders are a staple in many laboratories, but they come with several costly drawbacks:

1. High Cylinder Costs

The upfront cost of nitrogen cylinders can be significant, especially for labs that require multiple cylinders per month. Pricing varies depending on size and supplier, but the recurring need to purchase or replace cylinders creates an ongoing expense that can quickly add up. Unlike a fixed investment in a nitrogen generator, cylinder costs are a constant and unavoidable part of lab operations.

2. Monthly Rental Fees

Most gas suppliers charge a rental fee per cylinder, adding to the overall cost of maintaining a steady nitrogen supply. These fees might seem small at first, but when multiplied across multiple cylinders and months, they become a substantial recurring expense. Over time, these rental costs can easily surpass the price of investing in an in-house nitrogen generation system.

3. Delivery & Handling Expenses

Delivery costs vary but can add hundreds of dollars per month to your nitrogen expenses, especially if you're receiving frequent shipments. Beyond costs, frequent deliveries create workflow disruptions and safety concerns due to cylinder handling and storage. Each delivery requires time, coordination, and often additional fees, making cylinders an inefficient option for labs that require a reliable nitrogen supply.

4. Gas Waste

Did you know that most nitrogen cylinders leave about 10% of their gas unused due to pressure limitations? That means you're paying for nitrogen you can’t even use. Additionally, each time a cylinder runs empty, there is downtime involved in switching to a new one, causing further inefficiencies in lab operations.

5. Storage & Safety Risks

Cylinders require dedicated storage space and proper handling to prevent leaks, pressure hazards, and accidents. Many labs struggle with cylinder management, leading to compliance concerns and workflow inefficiencies. Storing multiple high-pressure cylinders also introduces potential safety risks, requiring strict adherence to safety protocols and regulatory standards.

The Smarter Alternative: Switching to a Nitrogen Generator

A nitrogen generator offers a cost-effective, on-demand solution for labs that need a steady nitrogen supply—without the ongoing expenses of cylinder rentals, refills, and deliveries. Here’s why more labs are making the switch:

  • Eliminate Cylinder Costs – No more purchases, rentals, or refills.
  • Reduce Long-Term Expenses – A one-time investment with minimal maintenance.
  • On-Demand Supply – Generate high-purity nitrogen whenever you need it.
  • No More Deliveries – Say goodbye to disruptions and recurring delivery fees.
  • Increased Safety & Efficiency – No handling of high-pressure cylinders.
  • Better Environmental ImpactReduce carbon emissions associated with cylinder deliveries and production.

Many labs find that a nitrogen generator pays for itself within a year—especially if they use multiple cylinders per month. Beyond the financial savings, labs that switch to a nitrogen generator experience greater efficiency, safety, and reliability in their daily operations.

Learn More: Nitrogen Generators for Sample Preparation: Everything you need to know

Watch Our Webinar: Improving Laboratory Workflows with Nitrogen Generation

Find Out If You’re Overpaying

Not sure if switching to a nitrogen generator makes sense for your lab? Use our "Am I Overpaying on My Nitrogen Gas Cylinders?" tool to compare your costs against industry benchmarks. Simply answer a few quick questions, and we’ll help you determine whether it’s time to make the switch.

Organomation
LinkedIn Logo
 

Related content

Determination of Authenticity of Manuka Honey Using the MALDI-8030 Benchtop Linear MALDI-TOF Mass Spectrometer

Applications
| 2026 | Shimadzu
Instrumentation
MALDI, LC/MS, LC/TOF
Manufacturer
Shimadzu
Industries
Food & Agriculture

Analysis of Inorganic Anions in Drinking Water According to EPA Method 300.1 Using Nexera IC -Part A

Applications
| 2026 | Shimadzu
Instrumentation
Ion chromatography
Manufacturer
Shimadzu
Industries
Food & Agriculture

Quality Evaluation of mRNA by Electrophoresis

Applications
| 2026 | Shimadzu
Instrumentation
Capillary electrophoresis
Manufacturer
Shimadzu
Industries
Pharma & Biopharma

LC/MS dMRM Method Refinement Expands Targeted Lipidomics Studies from Plasma to Cells and Tissues

Applications
| 2026 | Agilent Technologies
Instrumentation
LC/MS, LC/MS/MS, LC/QQQ
Manufacturer
Agilent Technologies
Industries
Lipidomics, Clinical Research

Sensitive Detection of Aflatoxins by the Agilent 1290 Infinity III Fluorescence Detector

Applications
| 2026 | Agilent Technologies
Instrumentation
HPLC
Manufacturer
Agilent Technologies
Industries
Food & Agriculture
 

Related articles

Alternatives to Traditional Fume Hoods: A Comprehensive Guide to Laboratory Containment Solutions
Article | Laboratories

Alternatives to Traditional Fume Hoods: A Comprehensive Guide to Laboratory Containment Solutions

Explore alternatives to traditional ducted fume hoods, including glove boxes, snorkel systems, ductless hoods, and specialized containment solutions for safer, energy-efficient laboratories.
Organomation
tag
share
more
Oligos Made Easy - Part 4: HILIC
Article | Academy

Oligos Made Easy - Part 4: HILIC

Discover how HILIC-MS is transforming oligonucleotide analysis. Learn retention principles, method development steps, and practical tips for achieving high-resolution, ion-pair-free separations.
KNAUER
tag
share
more
Advanced equipment for self-driving analytical AI laboratory
Article | Science and research

Advanced equipment for self-driving analytical AI laboratory

University of Amsterdam and Agilent partner to advance polymer analysis using 2D-LC-MS and AI-driven method development in a self-driving analytical laboratory.
University of Amsterdam
tag
share
more
Unraveling Neuroendocrine Cancer Research with Mass Spectrometry
Interview | Science and research

Unraveling Neuroendocrine Cancer Research with Mass Spectrometry

Dr. Rachael Guenter traces her path into neuroendocrine tumor research and explains how clinician partnerships and mass spectrometry accelerate translational discoveries—plus why “think zebras” matters.
Organomation
tag
share
more
 

Related content

Determination of Authenticity of Manuka Honey Using the MALDI-8030 Benchtop Linear MALDI-TOF Mass Spectrometer

Applications
| 2026 | Shimadzu
Instrumentation
MALDI, LC/MS, LC/TOF
Manufacturer
Shimadzu
Industries
Food & Agriculture

Analysis of Inorganic Anions in Drinking Water According to EPA Method 300.1 Using Nexera IC -Part A

Applications
| 2026 | Shimadzu
Instrumentation
Ion chromatography
Manufacturer
Shimadzu
Industries
Food & Agriculture

Quality Evaluation of mRNA by Electrophoresis

Applications
| 2026 | Shimadzu
Instrumentation
Capillary electrophoresis
Manufacturer
Shimadzu
Industries
Pharma & Biopharma

LC/MS dMRM Method Refinement Expands Targeted Lipidomics Studies from Plasma to Cells and Tissues

Applications
| 2026 | Agilent Technologies
Instrumentation
LC/MS, LC/MS/MS, LC/QQQ
Manufacturer
Agilent Technologies
Industries
Lipidomics, Clinical Research

Sensitive Detection of Aflatoxins by the Agilent 1290 Infinity III Fluorescence Detector

Applications
| 2026 | Agilent Technologies
Instrumentation
HPLC
Manufacturer
Agilent Technologies
Industries
Food & Agriculture
 

Related articles

Alternatives to Traditional Fume Hoods: A Comprehensive Guide to Laboratory Containment Solutions
Article | Laboratories

Alternatives to Traditional Fume Hoods: A Comprehensive Guide to Laboratory Containment Solutions

Explore alternatives to traditional ducted fume hoods, including glove boxes, snorkel systems, ductless hoods, and specialized containment solutions for safer, energy-efficient laboratories.
Organomation
tag
share
more
Oligos Made Easy - Part 4: HILIC
Article | Academy

Oligos Made Easy - Part 4: HILIC

Discover how HILIC-MS is transforming oligonucleotide analysis. Learn retention principles, method development steps, and practical tips for achieving high-resolution, ion-pair-free separations.
KNAUER
tag
share
more
Advanced equipment for self-driving analytical AI laboratory
Article | Science and research

Advanced equipment for self-driving analytical AI laboratory

University of Amsterdam and Agilent partner to advance polymer analysis using 2D-LC-MS and AI-driven method development in a self-driving analytical laboratory.
University of Amsterdam
tag
share
more
Unraveling Neuroendocrine Cancer Research with Mass Spectrometry
Interview | Science and research

Unraveling Neuroendocrine Cancer Research with Mass Spectrometry

Dr. Rachael Guenter traces her path into neuroendocrine tumor research and explains how clinician partnerships and mass spectrometry accelerate translational discoveries—plus why “think zebras” matters.
Organomation
tag
share
more
 

Related content

Determination of Authenticity of Manuka Honey Using the MALDI-8030 Benchtop Linear MALDI-TOF Mass Spectrometer

Applications
| 2026 | Shimadzu
Instrumentation
MALDI, LC/MS, LC/TOF
Manufacturer
Shimadzu
Industries
Food & Agriculture

Analysis of Inorganic Anions in Drinking Water According to EPA Method 300.1 Using Nexera IC -Part A

Applications
| 2026 | Shimadzu
Instrumentation
Ion chromatography
Manufacturer
Shimadzu
Industries
Food & Agriculture

Quality Evaluation of mRNA by Electrophoresis

Applications
| 2026 | Shimadzu
Instrumentation
Capillary electrophoresis
Manufacturer
Shimadzu
Industries
Pharma & Biopharma

LC/MS dMRM Method Refinement Expands Targeted Lipidomics Studies from Plasma to Cells and Tissues

Applications
| 2026 | Agilent Technologies
Instrumentation
LC/MS, LC/MS/MS, LC/QQQ
Manufacturer
Agilent Technologies
Industries
Lipidomics, Clinical Research

Sensitive Detection of Aflatoxins by the Agilent 1290 Infinity III Fluorescence Detector

Applications
| 2026 | Agilent Technologies
Instrumentation
HPLC
Manufacturer
Agilent Technologies
Industries
Food & Agriculture
 

Related articles

Alternatives to Traditional Fume Hoods: A Comprehensive Guide to Laboratory Containment Solutions
Article | Laboratories

Alternatives to Traditional Fume Hoods: A Comprehensive Guide to Laboratory Containment Solutions

Explore alternatives to traditional ducted fume hoods, including glove boxes, snorkel systems, ductless hoods, and specialized containment solutions for safer, energy-efficient laboratories.
Organomation
tag
share
more
Oligos Made Easy - Part 4: HILIC
Article | Academy

Oligos Made Easy - Part 4: HILIC

Discover how HILIC-MS is transforming oligonucleotide analysis. Learn retention principles, method development steps, and practical tips for achieving high-resolution, ion-pair-free separations.
KNAUER
tag
share
more
Advanced equipment for self-driving analytical AI laboratory
Article | Science and research

Advanced equipment for self-driving analytical AI laboratory

University of Amsterdam and Agilent partner to advance polymer analysis using 2D-LC-MS and AI-driven method development in a self-driving analytical laboratory.
University of Amsterdam
tag
share
more
Unraveling Neuroendocrine Cancer Research with Mass Spectrometry
Interview | Science and research

Unraveling Neuroendocrine Cancer Research with Mass Spectrometry

Dr. Rachael Guenter traces her path into neuroendocrine tumor research and explains how clinician partnerships and mass spectrometry accelerate translational discoveries—plus why “think zebras” matters.
Organomation
tag
share
more
 

Related content

Determination of Authenticity of Manuka Honey Using the MALDI-8030 Benchtop Linear MALDI-TOF Mass Spectrometer

Applications
| 2026 | Shimadzu
Instrumentation
MALDI, LC/MS, LC/TOF
Manufacturer
Shimadzu
Industries
Food & Agriculture

Analysis of Inorganic Anions in Drinking Water According to EPA Method 300.1 Using Nexera IC -Part A

Applications
| 2026 | Shimadzu
Instrumentation
Ion chromatography
Manufacturer
Shimadzu
Industries
Food & Agriculture

Quality Evaluation of mRNA by Electrophoresis

Applications
| 2026 | Shimadzu
Instrumentation
Capillary electrophoresis
Manufacturer
Shimadzu
Industries
Pharma & Biopharma

LC/MS dMRM Method Refinement Expands Targeted Lipidomics Studies from Plasma to Cells and Tissues

Applications
| 2026 | Agilent Technologies
Instrumentation
LC/MS, LC/MS/MS, LC/QQQ
Manufacturer
Agilent Technologies
Industries
Lipidomics, Clinical Research

Sensitive Detection of Aflatoxins by the Agilent 1290 Infinity III Fluorescence Detector

Applications
| 2026 | Agilent Technologies
Instrumentation
HPLC
Manufacturer
Agilent Technologies
Industries
Food & Agriculture
 

Related articles

Alternatives to Traditional Fume Hoods: A Comprehensive Guide to Laboratory Containment Solutions
Article | Laboratories

Alternatives to Traditional Fume Hoods: A Comprehensive Guide to Laboratory Containment Solutions

Explore alternatives to traditional ducted fume hoods, including glove boxes, snorkel systems, ductless hoods, and specialized containment solutions for safer, energy-efficient laboratories.
Organomation
tag
share
more
Oligos Made Easy - Part 4: HILIC
Article | Academy

Oligos Made Easy - Part 4: HILIC

Discover how HILIC-MS is transforming oligonucleotide analysis. Learn retention principles, method development steps, and practical tips for achieving high-resolution, ion-pair-free separations.
KNAUER
tag
share
more
Advanced equipment for self-driving analytical AI laboratory
Article | Science and research

Advanced equipment for self-driving analytical AI laboratory

University of Amsterdam and Agilent partner to advance polymer analysis using 2D-LC-MS and AI-driven method development in a self-driving analytical laboratory.
University of Amsterdam
tag
share
more
Unraveling Neuroendocrine Cancer Research with Mass Spectrometry
Interview | Science and research

Unraveling Neuroendocrine Cancer Research with Mass Spectrometry

Dr. Rachael Guenter traces her path into neuroendocrine tumor research and explains how clinician partnerships and mass spectrometry accelerate translational discoveries—plus why “think zebras” matters.
Organomation
tag
share
more
Other projects
GCMS
ICPMS
Follow us
FacebookX (Twitter)LinkedInYouTube
More information
WebinarsAbout usContact usTerms of use
LabRulez s.r.o. All rights reserved. Content available under a CC BY-SA 4.0 Attribution-ShareAlike