Scientists at IOCB Prague created MSⁿLib, a vast mass spectrometry library with millions of records, enabling rapid unknown compound identification and boosting drug discovery and biomedical AI.

Researchers at IOCB Prague developed a simple and universal late-stage iodine-125 labeling method for peptides and proteins, enabling faster, cheaper, and high-quality production for drug discovery.

Chemists at IOCB Prague developed a fast, robust SNAr-based method to synthesize drug-like atropisomers, unlocking access to hindered C–N bonds with practical and mild conditions.

A team led by Prof. Jan Konvalinka has developed a compound that destroys the yeast Cryptococcus neoformans – a fungus which is life-threatening for people with weakened immune systems – in laboratory settings.

Scientists at IOCB Prague created an eco-friendly method to recycle rare earths like neodymium from magnets, offering a sustainable alternative to mining and boosting EU & US raw material security.

Dr. Tomáš Pluskal, winner of the Neuron Award, and his team created DreaMS, a machine learning model that accelerates molecule analysis. Published in Nature Biotechnology.

A team at IOCB Prague revealed a novel phase where liquids flip rapidly between metal and nonmetal states. The theory, based on advanced modeling, was featured in Nature Communications.

The scientific team of Dr. Pavel Majer from the IOCB of the CAS has developed a new substance with the potential to treat the autoimmune disease alopecia areata, which is manifested by hair loss.

Roman and Anton Bushuiev joined experts from 14 institutes in MassSpecGym, a project to benchmark AI methods for discovering natural molecules from MS, aiding drug development, ecology, and space research.

Dr. Tomáš Pluskal has been accepted into the prestigious ‘Young Investigator Programme’ of the EMBO and has also secured the ERC grant.