The central question addressed in the presentation was “What do we know about (your) antibodies?”, highlighting how innovative techniques in mass spectrometry provide novel insights.

This week we bring to you applications by Shimadzu, Thermo Fisher Scientific, Agilent Technologies, and presentation by James Little Mass Spec Interpretation Services!

This year, Karel Šmejkal received the MU Rector’s Award for long-term excellence in research in the field of natural sciences and medicine.

We introduce multicolumn online 2D-LC approach that simplifies column screening and method development dramatically enabling us to combine multiple columns in both dimensions.

Comprehensive two-dimensional (2D) chromatography method combining LC, SFC, and HRMS with fragmentation (LC×SFC-HRMS/MS) was developed for structural characterisation of lignin.

The technique for automated comparative analysis of chromatograms across different samples as well as across different detectors using the same sample is demonstrated.

2D-LC/MS in a regulated biopharma environment: Challenges & applications

LC-GC×GC-TOF MS/FID is a powerful multidimensional analytical method for automated and reliable characterization of complex samples. Overview of the technique and application to mineral oil analysis in food.

In this study, the enantioselective separation of a wide range of medicinal substances (log p: 0.9-4.1) is evaluated using a combination of TRLC and Chiral-RPLC.

This study investigates possible configurations for the modulation of HILIC and RPLC using ASM in a selective comprehensive 2D-LC set-up (sHILIC x RPLC).