Gunacins, new compounds from Exobasidium, display strong anti-Leishmania and anti-Trypanosoma effects and also show antibacterial and antifungal activity.

Learn how to balance purity, yield, and throughput when scaling analytical HPLC methods to preparative chromatography.

Learn how to minimize peak tailing when analyzing basic compounds on type A silicas. Explore pH adjustment, mobile phase modifiers, and modern type B silica columns for sharper, more symmetrical peaks.

Learn how to develop robust HPLC methods for peptide analysis using systematic screening of column chemistry, pH, and gradients for optimal selectivity and reproducibility.

Discover practical tips to optimise LC systems for UHPLC performance on any HPLC. Learn how to reduce peak broadening, improve efficiency, and shorten runtimes.

Column contamination is a leading cause of shortened HPLC column lifetime, leading to high back pressure. Learn why it happens and how to prevent blocked frits with simple precautions.

Struggling with peak tailing of basic compounds in RP-LC using type A silica columns? Discover how low-pH buffers and silanol suppressors can improve peak shape—plus why type B silica is a better choice.

The study examines treated wastewater from Arctic cruise ships to identify pharmaceuticals and other contaminants, highlighting potential risks to sensitive polar marine environments.

How can capacity factors drive method robustness?

The effects of gradient on buffer capacity