In the week of April 6, the following webinars await you in the field of liquid phase and especially HPLC and LC/MS.<blockquote><h4><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinars">👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</a></h4>👉 Search and filter in the largest global database with over 5 500 GC, LC, MS and spectroscopy webinars.</blockquote><h5>1. Waters Corporation: Fit-for-purpose workflows for inositol stereoisomer profiling in dietary supplements and foods using single and tandem mass spectrometry</h5><ul><li>Tu, 7.4.2026 19:00 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/6030">Registration</a></li></ul>The aim of this webinar is to present analytical procedures capable of simultaneously separating and quantifying free inositol stereoisomers in both simple matrices and complex matrices.<h5>2. Thermo Fisher Scientific: Transforming Fuel Testing Performance with Combustion Ion Chromatography</h5><ul><li>We, 8.4.2026 07:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/6093">Registration</a></li></ul>Join us for an interactive session on how Combustion Ion Chromatography (C-IC) is transforming fuel testing performance in modern laboratories.<h5>3. SCIEX: Getting started with LC-MS/MS for PFAS</h5><ul><li>We, 8.4.2026 10:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/6102">Registration</a></li></ul>Learn how to build LC-MS/MS methods for PFAS analysis, achieve ultra-low detection limits, and gain practical skills for environmental and food testing in this expert-led webinar.<h5>4. Phenomenex: Extraction Face-Off: Choosing Between SLE and SPE</h5><ul><li>We, 8.4.2026 10:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/6092">Registration</a></li></ul>Understand how SLE and SPE work and how they are different from each other.<h5>5. Waters Corporation: RADIAN™ ASAP Mass Spectrometry for the Detection and Analysis of Explosive Traces</h5><ul><li>We, 8.4.2026 16:00 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/6031">Registration</a></li></ul>Explore how mass spectrometry enables rapid detection of trace explosives. Learn how RADIAN™ ASAP extends forensic and security workflows, supporting future screening technologies and ion-mobility innovation.<h5>6. Technology Networks: Label Free Quantitation: New Insights Into High-Throughput Proteomic Workflows</h5><ul><li>Th, 9.4.2026 16:00 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/5969">Registration</a></li></ul>Discover how next-generation LC–MS and the ZenoTOF 8600 enable robust, high-throughput LFQ proteomics, backed by insights from a large multi-laboratory benchmark study.

Webinars LabRulezLCMS Week 15/2026

<h4>Introduction&nbsp;</h4>Millions of tests, measurements and examinations are made every day in thousands of laboratories around the world. There are innumerable reasons underpinning them, for example: as a way of valuing goods for trade purposes; supporting healthcare and construction; checking the quality and safety of food and feed; and in forensic analysis and environmental monitoring. Virtually every aspect of society is supported in some way by analytical work.&nbsp;The cost of carrying out these measurements is high and additional costs may arise from decisions made on the basis of the results. For example, tests showing food to be unfit for consumption may result in compensation claims. In addition, tests confirming the presence of banned drugs could result in fines or imprisonment. Clearly it is important to make a correct measurement and be able to show that the result is correct.<h4>The validation/verification process</h4>Most analysts know that method validation/verification is important, but exactly why, how and when it should be done is not always clear.&nbsp;Method validation/verification is the process whereby the laboratory demonstrates whether or not a method is ‘fit for purpose’ (Fig. 1). This means that the tests carried out should be appropriate with respect to uncertainty, cost, time etc. The final report should present analytical data in such a way that the customer can, readily, interpret it and draw appropriate conclusions.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Eurachem_The_validation_verification_82742c1029.jpg" alt="Eurachem: Fig. 1. The method validation/verification process. The laboratory ‘translates’ the customer’s problem into an analytical requirement, i.e. the method performance required to solve the problem. Method validation/verification includes a stage where various performance characteristics are evaluated and then compared with analytical requirements." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Eurachem_The_validation_verification_82742c1029.jpg 124w," sizes="100vw" width="821" height="1029"><h4>The Eurachem Guide&nbsp;</h4>A <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/2242">Guide from Eurachem</a> (Fig. 2) gives practical advice on how method validation/verification can be accomplished. The Guide and its supplements [1-4]:&nbsp;<ul><li>Introduce the basic concepts related to method validation and method verification;&nbsp;</li><li>Indicate how to plan, record and report validation and verification studies to best support the statement of ‘fitness for purpose’;&nbsp;</li><li>Provide key definitions and the rationale behind the experiments for assessing the various performance characteristics and related topics (Fig. 3);&nbsp;</li><li>Include quick reference tables that suggest experiments together with the necessary statistical calculations for evaluation and reporting each performance characteristic;&nbsp;</li><li>Provide support to the analyst on how to make the best use of method validation data for setting up an internal quality control plan.</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Eurachem_The_Fitness_for_Purpose_of_Analytical_Methods_95fc1a74e3.jpg" alt="Eurachem: Fig. 2. The Eurachem Guide is available free of charge at www.eurachem.org." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Eurachem_The_Fitness_for_Purpose_of_Analytical_Methods_95fc1a74e3.jpg 135w," sizes="100vw" width="1062" height="1231"><h4>How should methods be validated/verified?</h4>The guide focuses on a single-laboratory approach to method validation/verification and gives guidance on planning, carrying out and reporting method validation and verification studies. Any method validation or verification study will require the laboratory to investigate several performance characteristics:<ul><li>Precision<ul><li>Repeatability&nbsp;</li><li>Intermediate precision</li></ul></li><li>Trueness</li><li>Selectivity</li><li>Working range</li><li>Analytical sensitivity</li><li>Limit of detection</li><li>Limit of quantification</li><li>Ruggedness</li></ul>Exactly which characteristics are studied will depend on the analytical application. Verification of the performance of a standard method requires substantially less work than validation of a method developed in-house. Legislative/sectoral requirements must also be considered.&nbsp;Sampling and subsampling can be part of the measurement or testing procedure and must, in those cases, be validated.

The importance of being fit for purpose

Is your current mass spectrometer limiting your lab’s capabilities? Whether you’re facing performance bottlenecks, rising maintenance costs, or simply ready to scale up, Thermo Fisher Scientific’s Trade-In / Trade-Up Program offers a seamless, cost-effective path to advanced LC-MS technology.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Upgrade_Smarter_Trade_In_Your_Current_LC_MS_System_and_Boost_Lab_Performance_Without_Breaking_Budget_a54b9c7019.jpg" alt="Thermo Fisher Scientific: Upgrade Smarter: Trade In Your Current LC-MS System and Boost Lab Performance Without Breaking Budget" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Upgrade_Smarter_Trade_In_Your_Current_LC_MS_System_and_Boost_Lab_Performance_Without_Breaking_Budget_a54b9c7019.jpg 245w," sizes="100vw" width="1024" height="512"><h3>Elevate lab productivity at a lower cost</h3>With the Trade-In program, you can turn your existing LC-MS, HPLC system, or Orbitrap mass analyzer—regardless of brand—into savings toward a newer, more powerful instrument. We’ll evaluate your current system’s residual value and apply it directly to your upgrade, helping you offset the cost while avoiding the hassle of selling, shipping, or decommissioning the old instrument yourself.Why Trade-In?Upgrading through the Trade-In program means more than saving money—it’s about gaining lab efficiency, performance, and peace of mind.Benefits of Trading In:<ul><li>Access high-performing Thermo Scientific mass spectrometers</li><li>Increase throughput, sensitivity, and data quality</li><li>Reduce total cost of ownership through improved reliability</li><li>Streamline the upgrade with free instrument removal</li><li>Simplify the process—no third-party brokers or middlemen</li></ul><h3>Explore our full range of MS instrumentation</h3>When you’re ready to upgrade, Thermo Scientific offers an extensive portfolio of cutting-edge LC-MS systems built to support high-throughput labs, complex workflows, and evolving analytical challenges.<ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=5&amp;manufacturerItems=3&amp;search=astral">Orbitrap Astral MS</a> Ultra-sensitive, high-throughput mass spectrometry for Omics and BioPharma applications</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=134&amp;manufacturerItems=3&amp;search=tribrid">Orbitrap Tribrid MS</a> Measure low-abundance molecules and characterize structural isomers and native complexes</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=5&amp;manufacturerItems=3&amp;search=Exploris+">Orbitrap Exploris MS</a> High-performance mass spectrometry with streamlined workflows and broad dynamic range</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=22&amp;manufacturerItems=3&amp;search=Stellar">Stellar MS</a> Robust quantitation and rapid full-scan MSn for improved productivity</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=20&amp;manufacturerItems=3&amp;search=plus">TSQ Plus Triple Quadrupole MS</a> Fast, reliable, and precise targeted quantitation for all molecule types</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=5&amp;manufacturerItems=3&amp;search=Exactive">Q Exactive Plus MS</a> Versatile solution for discovery and quantitation workflows, all in one instrument</li></ul>Take the next step toward modernizing your labWhether you’re working in pharma, biotech, academic research, or clinical research, modern LC-MS platforms deliver the sensitivity, resolution, and throughput required for today’s most demanding applications.And with the Trade-In program, you don’t have to delay progress due to cost.<h3>Looking for other affordable options?</h3>If a trade-in isn’t the right fit for your current needs, explore these additional affordability programs:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/content/lifetech/global/en/home/industrial/mass-spectrometry/mass-spectrometer-price-affordability-programs/certified-pre-owned-lc-ms.html">Explore refurbished systems</a></li></ul>Access factory-certified, reconditioned LC-MS systems at a fraction of the cost—fully tested and ready to deliver high-quality data.<ul><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/content/lifetech/global/en/home/industrial/mass-spectrometry/mass-spectrometer-price-affordability-programs/thermo-scientific-financial-solutions.html">Explore leasing &amp; financing solutions</a></li></ul>Flexible payment plans, leasing options, and deferred payments designed to meet your financial and operational needs.<h3>Upgrade now, pay less, get more</h3>It’s never been easier to transition your lab to next-gen mass spectrometry. Trade in your current system—Thermo Fisher Scientific or otherwise—and gain access to our latest technology, expert support, and proven reliability, all while staying within budget.<a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/content/lifetech/global/en/home/industrial/mass-spectrometry/mass-spectrometer-price-affordability-programs/mass-spectrometer-trade-upgrade.html">Start your trade-in today</a> Let us help you turn today’s tools into tomorrow’s capabilities.Visit us on&nbsp;<a target="_blank" rel="noopener noreferrer" href="https://www.linkedin.com/showcase/72003132/admin/dashboard/">LinkedIn:</a>&nbsp;#LCMS #promotions #affordability #TradeIn<blockquote><h5>Ema Ruzic</h5>Ema Ružić is a molecular biologist with a background in forensic biology who has transitioned into strategic marketing within the clinical research and toxicology space. Over the past five years at Thermo Fisher Scientific, she has progressed into her current role as Vertical Marketing Manager for Clinical Research &amp; Toxicology, where she leads strategic marketing initiatives that support solution positioning, market development, and customer engagement across regulated laboratory environments. Drawing on her foundation knowledge of the sciences, Ema brings a deep understanding of laboratory workflows and scientific challenges, enabling her to translate complex technologies into impactful marketing content. Her work bridges science and strategy, helping accelerate adoption of innovative solutions that advance clinical and forensic research. You may also see her at industry conferences and scientific events, where she engages with customers and partners to stay closely connected to the evolving needs of the community.</blockquote>

Upgrade Smarter: Trade In Your Current LC-MS System and Boost Lab Performance Without Breaking Budget

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Waters 2410 Refractive Index Detector (Refurbished)

The Waters 2410 Differential Refractometer is refractive index detector designed for use in liquid chromatography applications. This instrument offers reliable detection of analytes based on changes in the refractive index of the eluent. With a measurement range spanning from 5 × 10⁻⁸ to 5 × 10⁻³ refractive index units full scale (RIUFS), the 2410 excels in sensitivity and versatility, making it suitable for a wide variety of analytical applications.

Waters 474 Scanning Fluorescence Detector (Refurbished)

The Waters 474 Scanning Fluorescence Detector is analytical instrument designed to provide precise and sensitive spectrofluorometric analysis. The detector’s versatility and reliability make it suitable for applications ranging from trace metal detection to the analysis of organic and biological compounds. The detector’s versatility and reliability make it suitable for applications ranging from trace metal detection to the analysis of organic and biological compounds. 

Waters 2487 UV-Vis HPLC Detector (refurbished)

The Waters 2487 UV-Vis Detector is an HPLC detector designed to provide precise and reliable ultraviolet-visible spectroscopic detection. Renowned for its accuracy, sensitivity, and versatility, this detector offers exceptional performance for a wide range of applications in analytical laboratories.

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The importance of being fit for purpose

Webinars LabRulezLCMS Week 15/2026