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James Little - Mass Spec Interpretation Services
James Little - Mass Spec Interpretation Services

My name is James Little and my private consulting company is Mass Spec Interpretation Services. I contract for NIST, Wiley, and Sapec. Previously, I was a Research Fellow specializing in mass spectrometry at Eastman Chemical Company in Kingsport, TN and retired in early 2016 after >37 years of service. For 2017-2019, I did NMR as a limited service employee specializing in end group determinations for Eastman.

My main interest is the identification of organic compounds by mass spectrometry in organic mixtures. All the technical information on my web page was approved as technical session handouts, conference presentations, workshops, journal publications, courses, etc. for distribution outside Eastman. Other postings on this site are my own and do not necessarily represent Eastman’s positions, strategies or opinions. I also include a “little” information about my sailing experiences.

In 2017, I purchased a used Model S85 Tesla and starting to participate in electric vehicle events. In addition, I am a member of the choir at St. Paul’s Episcopal Church, play competitive duplicate bridge, and race sailboats on Watauga Lake.

 

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Article | Academy

Changes in Tandem (MS/MS) NIST23 Search Program (V3.0)

NIST2023 Library and Software Available in Early June. Many very significant improvements in the new version compared to 2020 version..
James Little/Mass Spec Interpretation Services
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Video | Academy

LC/MS Unknown Identifications Using MSMS Libraries Part VIII: Identification of Unknowns with “Spectraless” Libraries

This is a complimentary approach to the NIST search of MS/MS (Tandem) libraries. Seven other sessions in the series explore the use of NIST Search Software for the identification of unknowns.
James Little/Mass Spec Interpretation Services
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Library

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NIST/EPA/NIH EI-MS LIBRARY (2023 Release)

Others
| 2023 | NIST (James Little/Mass Spec Interpretation Services)
Instrumentation
Software
Manufacturer
Wiley
Industries

NIST Tandem Mass Spectral Library (2023 Release)

Others
| 2023 | NIST (James Little/Mass Spec Interpretation Services)
Instrumentation
Software
Manufacturer
Wiley
Industries

LCMS Unknown Identifications Using MSMS Libraries Part III: More Detailed Discussion of MSMS Hybrid Search

Presentations
| 2020 | James Little/Mass Spec Interpretation Services
Instrumentation
Software
Manufacturer
Wiley
Industries

LC/MS Unknown Identifications Using MSMS Libraries Part IV: Importing MSMS Spectra

Presentations
| 2020 | James Little/Mass Spec Interpretation Services
Instrumentation
Software
Manufacturer
Wiley
Industries
 

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