LCMS
More information
WebinarsAbout usContact usTerms of use
LabRulez s.r.o. All rights reserved. Content available under a CC BY-SA 4.0 Attribution-ShareAlike
James Little - Mass Spec Interpretation Services
James Little - Mass Spec Interpretation Services

My name is James Little and my private consulting company is Mass Spec Interpretation Services. I contract for NIST, Wiley, and Sapec. Previously, I was a Research Fellow specializing in mass spectrometry at Eastman Chemical Company in Kingsport, TN and retired in early 2016 after >37 years of service. For 2017-2019, I did NMR as a limited service employee specializing in end group determinations for Eastman.

My main interest is the identification of organic compounds by mass spectrometry in organic mixtures. All the technical information on my web page was approved as technical session handouts, conference presentations, workshops, journal publications, courses, etc. for distribution outside Eastman. Other postings on this site are my own and do not necessarily represent Eastman’s positions, strategies or opinions. I also include a “little” information about my sailing experiences.

In 2017, I purchased a used Model S85 Tesla and starting to participate in electric vehicle events. In addition, I am a member of the choir at St. Paul’s Episcopal Church, play competitive duplicate bridge, and race sailboats on Watauga Lake.

 

News

Toggle
Data Processing Using Thermo Freestyle Software with NIST MSMS Search for Compound Identifications (Elemental Composition with Freestyle)
Article | Video

Data Processing Using Thermo Freestyle Software with NIST MSMS Search for Compound Identifications (Elemental Composition with Freestyle)

This course shows how to identify unknowns in LCMS analysis employing the NIST MSMS search software. Part 5 discusses the the determination of molecular formulae with Thermo Freestyle software.
James Little/Mass Spec Interpretation Services
tag
share
more
Data Processing Using Thermo Freestyle Software with NIST MSMS Search for Compound Identifications (Setting Up NIST Search and Freestyle Parameters)
Article | Video

Data Processing Using Thermo Freestyle Software with NIST MSMS Search for Compound Identifications (Setting Up NIST Search and Freestyle Parameters)

This course shows how to identify unknowns in LCMS analysis employing the NIST MSMS search software. Part 3 discusses basic settings for Thermo Freestyle software and the NIST 2023 Search.
James Little/Mass Spec Interpretation Services
tag
share
more
 

Wrote about us

Toggle
News from LabRulezLCMS Library - Week 42, 2024
Article | Application

News from LabRulezLCMS Library - Week 42, 2024

We bring you posters, presentations, applications, and other documents by Thermo Fisher Scientific, Agilent Technologies, Shimadzu, Waters Corporation, and James Little Mass Spec Interpretation Services!
LabRulez
tag
share
more
News from LabRulezLCMS Library - Week 41, 2024
Article | Application

News from LabRulezLCMS Library - Week 41, 2024

This week we bring to you applications by Shimadzu, Thermo Fisher Scientific, Agilent Technologies, and presentation by James Little Mass Spec Interpretation Services!
LabRulez
tag
share
more
 

Library

Toggle

NIST/EPA/NIH EI-MS LIBRARY (2023 Release)

Others
| 2023 | NIST (James Little/Mass Spec Interpretation Services)
Instrumentation
Software
Manufacturer
Wiley
Industries

NIST Tandem Mass Spectral Library (2023 Release)

Others
| 2023 | NIST (James Little/Mass Spec Interpretation Services)
Instrumentation
Software
Manufacturer
Wiley
Industries

LCMS Unknown Identification with NIST Search Using MSMS Libraries

Presentations
| 2024 | James Little/Mass Spec Interpretation Services
Instrumentation
Software, LC/MS, LC/MS/MS, LC/QQQ
Manufacturer
Agilent Technologies, Wiley
Industries

Thermo Freestyle Easily Sends MSMS Spectra to NIST Search

Presentations
| 2024 | James Little/Mass Spec Interpretation Services
Instrumentation
Software, LC/MS, LC/HRMS, LC/MS/MS, LC/Orbitrap
Manufacturer
Thermo Fisher Scientific
Industries
 

Related content

Determination of Authenticity of Manuka Honey Using the MALDI-8030 Benchtop Linear MALDI-TOF Mass Spectrometer

Applications
| 2026 | Shimadzu
Instrumentation
MALDI, LC/MS, LC/TOF
Manufacturer
Shimadzu
Industries
Food & Agriculture

Analysis of Inorganic Anions in Drinking Water According to EPA Method 300.1 Using Nexera IC -Part A

Applications
| 2026 | Shimadzu
Instrumentation
Ion chromatography
Manufacturer
Shimadzu
Industries
Food & Agriculture

Quality Evaluation of mRNA by Electrophoresis

Applications
| 2026 | Shimadzu
Instrumentation
Capillary electrophoresis
Manufacturer
Shimadzu
Industries
Pharma & Biopharma

LC/MS dMRM Method Refinement Expands Targeted Lipidomics Studies from Plasma to Cells and Tissues

Applications
| 2026 | Agilent Technologies
Instrumentation
LC/MS, LC/MS/MS, LC/QQQ
Manufacturer
Agilent Technologies
Industries
Lipidomics, Clinical Research

Sensitive Detection of Aflatoxins by the Agilent 1290 Infinity III Fluorescence Detector

Applications
| 2026 | Agilent Technologies
Instrumentation
HPLC
Manufacturer
Agilent Technologies
Industries
Food & Agriculture
Other projects
GCMS
ICPMS
Follow us
FacebookX (Twitter)LinkedInYouTube
More information
WebinarsAbout usContact usTerms of use
LabRulez s.r.o. All rights reserved. Content available under a CC BY-SA 4.0 Attribution-ShareAlike