James Little - Mass Spec Interpretation Services
James Little - Mass Spec Interpretation Services

My name is James Little and my private consulting company is Mass Spec Interpretation Services. I contract for NIST, Wiley, and Sapec. Previously, I was a Research Fellow specializing in mass spectrometry at Eastman Chemical Company in Kingsport, TN and retired in early 2016 after >37 years of service. For 2017-2019, I did NMR as a limited service employee specializing in end group determinations for Eastman.

My main interest is the identification of organic compounds by mass spectrometry in organic mixtures. All the technical information on my web page was approved as technical session handouts, conference presentations, workshops, journal publications, courses, etc. for distribution outside Eastman. Other postings on this site are my own and do not necessarily represent Eastman’s positions, strategies or opinions. I also include a “little” information about my sailing experiences.

In 2017, I purchased a used Model S85 Tesla and starting to participate in electric vehicle events. In addition, I am a member of the choir at St. Paul’s Episcopal Church, play competitive duplicate bridge, and race sailboats on Watauga Lake.

 

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In-Source Fragmentation Searches in NIST26 Chromatogram Window
Article | Academy

In-Source Fragmentation Searches in NIST26 Chromatogram Window

Learn how to recognize and search in-source fragmentation spectra in NIST26 using chromatogram results, Score (Unfiltered), and MS/MS Library Search for compound identification.
James Little/Mass Spec Interpretation Services
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Processing MS/MS Data in NIST26 Chromatogram Window
Article | Academy

Processing MS/MS Data in NIST26 Chromatogram Window

A practical guide to processing LC-MS/MS data in the NIST26 Chromatogram Window, from parameter setup and library searching to identification review and result export.
James Little/Mass Spec Interpretation Services
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Wrote about us

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News from LabRulezLCMS Library - Week 42, 2024
Article | Application

News from LabRulezLCMS Library - Week 42, 2024

We bring you posters, presentations, applications, and other documents by Thermo Fisher Scientific, Agilent Technologies, Shimadzu, Waters Corporation, and James Little Mass Spec Interpretation Services!
LabRulez
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News from LabRulezLCMS Library - Week 41, 2024
Article | Application

News from LabRulezLCMS Library - Week 41, 2024

This week we bring to you applications by Shimadzu, Thermo Fisher Scientific, Agilent Technologies, and presentation by James Little Mass Spec Interpretation Services!
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Library

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Conversion to mzML Format for NIST26 Chromatogram Processing

Presentations
| 2026 | James Little/Mass Spec Interpretation Services
Instrumentation
Software, LC/MS, LC/MS/MS
Manufacturer
Wiley
Industries
Other

NIST26 FREE Demonstration (Demo) Copy of MS/MS Integrated Processing

Presentations
| 2026 | James Little/Mass Spec Interpretation Services
Instrumentation
Software, LC/MS, LC/MS/MS
Manufacturer
Wiley
Industries
Other

Searching Normal NIST Search with Chromatogram Results

Presentations
| 2026 | James Little/Mass Spec Interpretation Services
Instrumentation
Software, LC/MS, LC/MS/MS
Manufacturer
Wiley
Industries
Other

In-Source Fragmentation Searches in NIST26 Chromatogram Window

Presentations
| 2026 | James Little/Mass Spec Interpretation Services
Instrumentation
Software, LC/MS, LC/MS/MS
Manufacturer
Wiley
Industries
Other
 

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