Applications from the field of Clinical Research focused on LC/HRMS - page 28

Characterization of IgG1 monoclonal antibody (mAb) oxidation variants at intact, subunit and peptide levels

Applications

| 2020 | Thermo Fisher Scientific

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Clinical Research

Determination of Molecular Mass and Quantification of Oligonucleotide Therapeutics Using Quadrupole Time-of-Flight Mass Spectrometer LCMS™-9030

Applications

| 2020 | Shimadzu

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Shimadzu

Industries

Clinical Research

Confident peptide mapping and disulfide bond analysis of an IgG2 monoclonal antibody

Applications

| 2020 | Thermo Fisher Scientific

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Proteomics , Clinical Research

Incorporating CCS values to enable 4-dimensional annotation of metabolic features

Applications

| 2020 | Bruker

Ion Mobility, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

Ion Mobility, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Bruker

Industries

Clinical Research

Rapid Oligonucleotides QC with Automated High Resolution ESI-LCMS and BioPharma Compass

Applications

| 2020 | Bruker

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Bruker

Industries

Clinical Research

Increased Throughput for the Characterization of Bispecific Antibodies on Subunit Level using SelexION® Differential Mobility Separation (DMS) Technology

Applications

| 2020 | SCIEX

Ion Mobility, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

Ion Mobility, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

SCIEX

Industries

Clinical Research

Bruker timsTOF fleX - MALDI Guided SpatialOMx

Guides

| 2020 | Bruker

Ion Mobility, MALDI, MS Imaging, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

Ion Mobility, MALDI, MS Imaging, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Bruker

Industries

Clinical Research

Same Day HCP Workflow Has Become Reality!

Others

| 2020 | Bruker

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Bruker

Industries

Clinical Research

Routine analysis of drug to antibody ratio and drug distribution with maXis II

Applications

| 2020 | Bruker

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Bruker

Industries

Clinical Research

Real-Time Search enables a new gold standard for TMT quantitation accuracy on the Orbitrap Eclipse Tribrid mass spectrometer

Applications

| 2020 | Thermo Fisher Scientific

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Clinical Research