Characterization and Monitoring of mAb Charge Variants via Online IEX-MS

 

Similar PDF

Toggle
Welcome to Waters Luncheon Seminar ©2019 Waters Corporation COMPANY CONFIDENTIAL 1 Your Feedback will be very much appreciated! Please provide your feedback and you will get a gift set at reception! Column-shaped pens ©2019 Waters Corporation COMPANY CONFIDENTIAL 2 Improving…
Key words
confidential, confidentialcompany, companyiex, iexvariant, variantmab, mabcharge, chargebatch, batchionhance, ionhancebuffer, buffervanguard, vanguardbioresolve, bioresolveides, idesscx, scxacidic, acidictrastuzumab
ONLINE IEX-MS CHARACTERIZATION AND MONITORING OF MAB CHARGE HETEROGENEITY USING AN OPTIMIZED CATION EXCHANGE RESIN AND COMPACT TOF MASS SPECTROMETER Samantha Ippoliti1, Qi Wang1, Ying Qing Yu1, Matthew A. Lauber1, Henry Shion1 1 Waters Corporation, Milford, MA, USA IdeS-Digested Trastuzumab…
Key words
iex, iexvariants, variantsdeamidation, deamidationcharge, chargeacidic, acidictrastuzumab, trastuzumabmab, mabmain, mainconformational, conformationalassignmentb, assignmentbbasic, basicnative, nativetof, tofpossible, possiblemass
Online IEX-MS Characterization and Monitoring of mAb Charge Heterogeneity Using an Optimized Cation Exchange Resin and Compact TOF Mass Spectrometer Samantha Ippoliti1, Qi Wang1, Ying Qing Yu1, Matthew A. Lauber1, Henry Shion1 1 Waters Corporation, Milford, MA, USA INTRODUCTION RESULTS…
Key words
variants, variantsiex, iexcharge, chargedeamidation, deamidationacidic, acidictrastuzumab, trastuzumabmab, mabmain, mainconformational, conformationalassignmentb, assignmentbbasic, basicnative, nativeexchange, exchangepossible, possiblemass
[ APPLICATION NOTE ] Online IEX-MS of mAb Charge Variants Using a BioResolve SCX mAb Column, IonHance CX-MS pH Concentrates, and BioAccord System Samantha Ippoliti, Andrew Schmudlach, Matthew A. Lauber, and Ying Qing Yu Waters Corporation, Milford, MA, USA APPLICATION…
Key words
iex, iexcharge, chargemab, mabmass, massacquity, acquitybioresolve, bioresolveides, idesrda, rdabioaccord, bioaccordmain, mainacidic, acidicscx, scxelectrophoresis, electrophoresisvariant, variantvariants
Other projects
Follow us
More information
WebinarsAbout usContact usTerms of use
LabRulez s.r.o., all rights reserved.