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STRATEGIES TO EVALUATE AND MONITOR FORCED DEGRADATION STUDIES USING A DUAL DETECTION (UV-MS) SYSTEM Paula Hong, and Patricia R. McConville Waters Corporation, Milford, MA 01757 INTRODUCTION Forced degradation studies are typically performed to understand the degradation pathway of pharmaceuticals. Given…
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[ APPLICATION NOTEBOOK ] ACQUITY QDa Detector QC APPLICATIONS COMPENDIUM EDITION 2 Dear Colleague The 2013 introduction of the ACQUITY™ QDa™ Detector was a breakthrough in Chromatography and Mass Spectrometry integration. It was the fulfilment of a vision 20 years…
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[ APPLICATION NOTEBOOK ] IMPURITIES Developing Safe and Effective Drugs INT RODUCTION NAVIGATION T he pharmaceutical industry is integral in maintaining public health by providing therapeutic and preventative medicines. T he cornerstones of bringing new medicines to market are quality,…
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[ APPLICATION NOTE ] Effective Determination of Pharmaceutical Impurities by Two Dimensional Liquid Chromatography Zhimin Li, Paula Hong, and Patricia McConville Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ INTRODUCTION Increase productivity through targeted Analysis of many pharmaceutical compounds…
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