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STRATEGIES TO EVALUATE AND MONITOR FORCED DEGRADATION STUDIES USING A DUAL DETECTION (UV-MS) SYSTEM

 

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THE USE OF A TRIPLE DETECTION SYSTEM (UV, ELSD, MS) FOR PHARMACEUTICAL DEGRADATION STUDIES Paula Hong, Aaron Phoebe, and Patricia R. McConville Waters Corporation, 34 Maple Street, Milford, MA, USA, 01757 METHODS 0.60 3.50 0.0 0.0 6 6.50 5.0 95.0…
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A Stress Testing Study of Glimepiride Drug Substance Utilizing UPLC/MS Methodology Michael D. Jones, Jessalynn Wheaton, Mary Jo Wojtusik, and Robert S. Plumb Waters Corporation, Milford, MA, USA INT RODUC T ION Forced degradation or stress testing studies are done…
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[ APPLICATION NOTE ] Probing for Packaging Migrants in a Pharmaceutical Impurities Assay Using UHPLC with UV and Mass Detection Michael Jones Waters Corporation, Wilmslow, UK APPLICATION BENEFITS ■■ ■■ ■■ INTRODUCTION The ACQUITY™ Arc™ System is a The synthesis…
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[ APPLICATION NOTEBOOK ] IMPURITIES Developing Safe and Effective Drugs INT RODUCTION NAVIGATION T he pharmaceutical industry is integral in maintaining public health by providing therapeutic and preventative medicines. T he cornerstones of bringing new medicines to market are quality,…
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