High-Throughput Analysis of Cytochrome P450 Inhibition in Intact Human Hepatocytes
Applications | 2014 | Agilent TechnologiesInstrumentation
LC/MS, LC/MS/MS, LC/QQQ
IndustriesClinical Research
ManufacturerAgilent Technologies
Key wordshepatocytes, inhibition, sip, cyp, rapidfire, activity, sensor, vitro, log, desethylamodiaquine, hlms, hydralazine, naphthoflavone, cryopreserved, throughput, positive, were, dose, relative, orphenadrine, ultrafast, dextrorphan, hepatocyte, sulfaphenazole, itraconazole, quinidine, hydroxybupropion, him, ketoconazole, isoform, agilent, adme, omeprazole, gemfibrozil, analysis, quercetin, human, midazolam, inhibitor, verapamil, masshunter, substrate, luoxeteine, steamline, ticoplidine, incubation, admet, cryopreservation, diethyldithiocarbamate, ddc
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rapidfire, rapidfirenadph, nadphinhibitor, inhibitornaph, naphmidazolam, midazolamremaining, remainingactivity, activityinhibition, inhibitioncyp, cypazamulin, azamulindrug, drugcytochrome, cytochromeritonavir, ritonavirwithout, withoutthroughput
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dextrorphan, dextrorphanmetaboquan, metaboquandmpk, dmpkacetaminophen, acetaminophencassetting, cassettingmephenytoin, mephenytoindiscovery, discoverymetabolites, metabolitesplatform, platformpaclitaxel, paclitaxelphenacetin, phenacetinseparate, separateinitial, initialbiomedical, biomedicalmetoprolol