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ApplicationNote: 408Developing a Method to Protect the Integrityof Racing Using Targeted SRM: Detection andQuantitation of rhEPO/DPO in Horse PlasmaScott M. Peterman1, Cornelius Uboh2, Fuyu Guan2,3, Lawrence Soma3, Eric Birks3, and Jinwen Chen3Thermo Fisher Scientific, Somerset, NJ, USA; 2Pennsylvania Equine Toxicology...
Key words
rhepo, rhepodpo, dpolabeled, labeledhorse, horseabundance, abundancepeptides, peptidesrelative, relativeplasma, plasmaalgaqkeais, algaqkeaisgklklytgea, gklklytgeappdaasaapl, ppdaasaaplwkrmevgqqa, wkrmevgqqaunlabeled, unlabeledtargeted, targetedracing
Agilent-NISTmAbPeptide MappingAgilent BioHPLC ColumnsApplication Compendium ContentsAgilent-NISTmAb Standard (P/N 5191-5744; 5191-5745) was aliquoted fromNISTmAb RM 8671 batch. Quality control (QC) testing is performed usingAgilent LC-MS system. QC batch release test includes aggregate profile, chargevariants and intact mass information. A certificate of analysis...
Key words
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Enhancing The Quality Of PeptideMapping Separation For TheAnalysis Of PTMApplication NoteBiotherapeutics and BiosimilarsAuthorIntroductionSuresh Babu C.V.Post-translational modifications (PTMs) on proteins such as monoclonal antibodies(mAbs) are critical quality attributes (CQAs) that define the drug efficacy andsafety. Characterization of PTMs is a difficult...
Key words
peptide, peptidecounts, countsntaylqmnslr, ntaylqmnslradvancebio, advancebiodltmisr, dltmisrmab, mabeeeqynstr, eeeqynstrptms, ptmsdeamidated, deamidatedplus, plusdigest, digestmapping, mappingseparation, separationnonoxidized, nonoxidizedtryptic
Comprehensive Characterization of the N and O-Linked Glycosylationof a Recombinant Human EPOMatthew A. Lauber, Stephan M. Koza, and Erin E. ChambersWaters Corporation, Milford, MA, USAA P P L I C AT I O N B E N E F I...
Key words
linked, linkedrhepo, rheporapifluor, rapifluorglycan, glycanepo, epoglycans, glycansglycosylation, glycosylationrecombinant, recombinanthilic, hilichuman, humanglycoworks, glycoworkserythropoietin, erythropoietincharacterization, characterizationcomprehensive, comprehensivedeglycosylated