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Enhancing The Quality Of Peptide Mapping Separation For The Analysis Of PTM

 

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Application Note Biotherapeutics and Biosimilars In-depth Peptide Mapping with Iterative MS/MS Acquisition on the Agilent 6545XT AdvanceBio LC/Q‑TOF Authors Introduction Linfeng Wu and David L. Wong Agilent Technologies, Inc. Santa Clara, CA, USA Therapeutic monoclonal antibodies (mAbs) represent one of…
Key words
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Application Note Biotherapeutics and Biosimilars LC/MS/MS Peptide Mapping Comparison of Innovator and Biosimilars of Rituximab Author Suresh Babu C.V. Agilent Technologies, Inc. Abstract The development and manufacturing of biosimilars require comparability studies with innovator biotherapeutic products. This Application Note presents…
Key words
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Fast and Efficient Peptide Mapping of a Monoclonal Antibody (mAb): UHPLC Performance with Superficially Porous Particles Application Note Biotherapeutics and Biosimilars Authors Introduction James Martosella, Alex Zhu Peptide mapping by reversed-phase (RP) chromatography is the mainstay technique in biotherapeutic analysis,…
Key words
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Peptide Mapping of Innovator and Biosimilar Monoclonal Antibody Using an Agilent 1290 Infinity UHPLC Coupled to an Agilent 6550 iFunnel Q-TOF LC/MS System Application Note Author Introduction Ravindra Gudihal Monoclonal antibodies (mAbs) are becoming one of the important classes of…
Key words
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