Agilent AdvanceBio SEC for Peptides, Proteins & ADC Analysis

Others | 2021 | Agilent TechnologiesInstrumentation
Consumables, LC columns
Industries
Proteomics
Manufacturer
Agilent Technologies
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Fast Separations forAggregates and FragmentsAgilent AdvanceBio SEC 200 Å 1.9 μm columns Boost Your Productivity with FastAggregate and Fragment AnalysisSize exclusion chromatography (SEC) is a reference method for the qualitative andquantitative analysis of protein aggregates, such as monoclonal antibodies (mAbs)and antibody...
Key words
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High-Resolution Analysisof Peptides and ProteinsNew AdvanceBio SEC 120 Å 1.9 μm columns Optimize Your SEC Analysiswith High Resolution and ReducedSecondary InteractionsSize exclusion chromatography (SEC) is a reference method for the analysis of proteinaggregates. These aggregates are critical quality attributes (CQAs) because...
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Consumables Workflow Ordering GuideAnalyzing Monoclonal Antibody(mAb) Fragments and Dimers UsingSize Exclusion Chromatography (SEC)Low molecular weight (LMW) fragments and high molecular weight (HMW)dimers and aggregates can be formed from biotherapeutic proteins during drugdevelopment, storage, shipment, or delivery. These size variants are...
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Consumables Workflow Ordering GuideAnalyzing Monoclonal Antibody(mAbs) and mAb-DerivedTherapeutics Using Native SEC-MSThe quantitation of aggregates is of particular concern for protein-based-therapiesgiven their potential effect on efficacy and immunogenicity. Size exclusionchromatography (SEC) combined with UV detection is the gold standard approachfor measuring...
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