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Improved molecular detection and acquisition speed using DESI mass spectrometry imaging quadrupole based mass spectrometer Emmanuelle Claude1, Wei Rao1, Zoltan Takats2, Emrys Jones1 1 Waters Corporation, Stamford Rd, Wilmslow, SK9 4AX, UK; 2 Department of Metabolism, Digestion and Reproduction, Imperial…
Key words
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NOVEL TARGETED DESI MRM TQ SYSTEM PROVIDING INCREASED SENSITIVITY AND ACQUISITION SPEED FOR MASS SPECTROMETRY IMAGING Emmanuelle Claude1, Steven Pringle1, Joanne Ballantyne1 1 Waters Corporation, Wilmslow, UK INTRODUCTION Gefitinib was detected with a S/N ~ 2,500 and was at least…
Key words
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[ TECHNOLOGY BRIEF ] DESI-Mass Spectrometry Imaging Investigation of Discrete and Cassette Drug Dosed Tissues Philippa J Hart,¹ Andreas Danhorn,² Mark Towers,¹ and Emmanuelle Claude¹ ¹Waters Corporation, Wilmslow, UK, ²Imperial College, London, UK Mass spectrometry imaging for the distribution of…
Key words
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MULTI-STEP WORKFLOW FOR VISUALIZATION OF DRUG/METABOLITES AND METABOLISM WITH DESI TQ AND DESI Q-TOF MASS SPECTROMETERS Emmanuelle Claude1; Naysha Munjoma1; Alex Birsan3, Ian Wilson2, Joanne Ballantyne1 1 Waters Corporation, Wilmslow; 2Division of Systems Medicine, Department of Metabolism Department of Metabolism,…
Key words
desi, desiimaging, imagingmsi, msigefitinib, gefitinibwere, weredmpk, dmpkmrm, mrmspectrometers, spectrometersputative, putativemetabolites, metabolitesstudies, studiestissues, tissuestargeted, targetedperformed, performedusing
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