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Improved molecular detection and acquisition speed using DESI mass spectrometry imaging quadrupole based mass spectrometer

 

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IMPROVED SELECTIVITY AND ACQUISITION SPEED USING DESI QUADRUPOLE BASED MASS SPECTROMETER 1 Emmanuelle Claude, 1Wei Rao, 2Zoltan Takats, 1Emrys Jones 1 Waters Corporation, Wilmslow, UK; 2Department of Metabolism, Digestion and Reproduction, Imperial College London, South Kensington Campus, London, UK INTRODUCTION…
Key words
desi, desiimaging, imagingxevo, xevoterfenadine, terfenadineenkephalin, enkephalinmrm, mrmsprayer, sprayerion, ionexperiment, experimentbeen, beencarboxyterfenadine, carboxyterfenadinedesmethylerlotinib, desmethylerlotinibdidesmethylerlotinib, didesmethylerlotinibhydroxyolanzapine, hydroxyolanzapineleucine
NOVEL TARGETED DESI MRM TQ SYSTEM PROVIDING INCREASED SENSITIVITY AND ACQUISITION SPEED FOR MASS SPECTROMETRY IMAGING Emmanuelle Claude1, Steven Pringle1, Joanne Ballantyne1 1 Waters Corporation, Wilmslow, UK INTRODUCTION Gefitinib was detected with a S/N ~ 2,500 and was at least…
Key words
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[ TECHNOLOGY BRIEF ] DESI-Mass Spectrometry Imaging Investigation of Discrete and Cassette Drug Dosed Tissues Philippa J Hart,¹ Andreas Danhorn,² Mark Towers,¹ and Emmanuelle Claude¹ ¹Waters Corporation, Wilmslow, UK, ²Imperial College, London, UK Mass spectrometry imaging for the distribution of…
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MULTI-STEP WORKFLOW FOR VISUALIZATION OF DRUG/METABOLITES AND METABOLISM WITH DESI TQ AND DESI Q-TOF MASS SPECTROMETERS Emmanuelle Claude1; Naysha Munjoma1; Alex Birsan3, Ian Wilson2, Joanne Ballantyne1 1 Waters Corporation, Wilmslow; 2Division of Systems Medicine, Department of Metabolism Department of Metabolism,…
Key words
desi, desiimaging, imagingmsi, msigefitinib, gefitinibwere, weredmpk, dmpkmrm, mrmspectrometers, spectrometersputative, putativemetabolites, metabolitesstudies, studiestissues, tissuestargeted, targetedperformed, performedusing
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