Rapid Analysis of Synthetic mRNA Cap Structure Using Ion-Pairing RPLC with the BioAccord LC-MS SystemApplications | 2021 | WatersInstrumentation
LC/TOF, LC/HRMS, LC/MS
Industries
Clinical Research
Manufacturer
Waters
Key words

 

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Application NoteImproved Chromatographic Analysis ofOligonucleotides with ACQUITY PREMIEROligonucleotide BEH C18 ColumnsMartin Gilar, Zhimin Li, Jason MacLeanWaters Corporation AbstractThis application note illustrates sources of oligonucleotide loss due to adsorption on metalliccolumn hardware (frits). Solutions, columns, and best practices for improved oligonucleotideanalysis are...
Key words
oligonucleotide, oligonucleotideoligonucleotides, oligonucleotidesmiser, misersurfaces, surfacesmetallic, metallicfrit, fritadsorption, adsorptionuplc, uplcacquity, acquitypremier, premierstainless, stainlesssteel, steelhps, hpsmaxpeak, maxpeakoligodeoxythymidine
[ BIOACCORD SYSTEM WITH ACQUITY PREMIER ]Routine BiopharmaceuticalAnalysis – AcceleratedACCESS | COMPLIANCE | QUALITY | EFFICIENCY [ BIOACCORD SYSTEM WITH ACQUITY PREMIER ]Improving lab efficiency without sacrificing results quality iscritical, but that isn’t easy. Now you can achieve high qualitydata while...
Key words
bioaccord, bioaccordpremier, premieracquity, acquitysystem, systemdata, datapennyk, pennykachieve, achievequality, qualitycompliant, compliantconventional, conventionalminimizing, minimizingmam, mamhps, hpsproductive, productivemetal
Application NoteAnalysis of Oligonucleotide Impurities on theBioAccord System with ACQUITY PremierCatalin E. Doneanu, Chris Knowles, Jonathan Fox, Emma Harry, Ying Qing Yu, Joseph Fredette, Weibin ChenWaters CorporationAbstractThis application note demonstrates an automated, compliance-ready LC-MS workflow for purity analysis andintact mass...
Key words
oligonucleotide, oligonucleotidepremier, premierbioaccord, bioaccordacquity, acquityimpurities, impuritiessystem, systemanalysis, analysisost, ostoligonucleotides, oligonucleotidesconfirmation, confirmationintact, intactpreceding, precedingimpurity, impurityhps, hpsfluidic
307379: Rapid Analysis of Synthetic mRNA Cap Structure using Ion Pairing Reversed Phase LiquidChromatography coupled to Mass SpectrometryJennifer M. Nguyen1, Siu-Hong Chan2, Bijoyita Roy2, Martin Gilar1, Brett Robb2, Weibin Chen1, Matthew A. Lauber11 Waters Corporation, Milford, MA, USA; 2 New...
Key words
synthetic, syntheticoligonucleotides, oligonucleotidesprobe, probernase, rnasemrna, mrnauhplc, uhplcfifth, fifthsurface, surfacecapping, cappingcoupled, coupledheavily, heavilyrna, rnamarked, markedpairing, pairingdispersion

Rapid Analysis of Synthetic mRNA Cap Structure Using Ion-Pairing RPLC with the BioAccord LC-MS SystemApplications | 2021 | WatersInstrumentation
LC/TOF, LC/HRMS, LC/MS
Industries
Clinical Research
Manufacturer
Waters
Key words

 

Similar PDF

Toggle
Application NoteImproved Chromatographic Analysis ofOligonucleotides with ACQUITY PREMIEROligonucleotide BEH C18 ColumnsMartin Gilar, Zhimin Li, Jason MacLeanWaters Corporation AbstractThis application note illustrates sources of oligonucleotide loss due to adsorption on metalliccolumn hardware (frits). Solutions, columns, and best practices for improved oligonucleotideanalysis are...
Key words
oligonucleotide, oligonucleotideoligonucleotides, oligonucleotidesmiser, misersurfaces, surfacesmetallic, metallicfrit, fritadsorption, adsorptionuplc, uplcacquity, acquitypremier, premierstainless, stainlesssteel, steelhps, hpsmaxpeak, maxpeakoligodeoxythymidine
[ BIOACCORD SYSTEM WITH ACQUITY PREMIER ]Routine BiopharmaceuticalAnalysis – AcceleratedACCESS | COMPLIANCE | QUALITY | EFFICIENCY [ BIOACCORD SYSTEM WITH ACQUITY PREMIER ]Improving lab efficiency without sacrificing results quality iscritical, but that isn’t easy. Now you can achieve high qualitydata while...
Key words
bioaccord, bioaccordpremier, premieracquity, acquitysystem, systemdata, datapennyk, pennykachieve, achievequality, qualitycompliant, compliantconventional, conventionalminimizing, minimizingmam, mamhps, hpsproductive, productivemetal
Application NoteAnalysis of Oligonucleotide Impurities on theBioAccord System with ACQUITY PremierCatalin E. Doneanu, Chris Knowles, Jonathan Fox, Emma Harry, Ying Qing Yu, Joseph Fredette, Weibin ChenWaters CorporationAbstractThis application note demonstrates an automated, compliance-ready LC-MS workflow for purity analysis andintact mass...
Key words
oligonucleotide, oligonucleotidepremier, premierbioaccord, bioaccordacquity, acquityimpurities, impuritiessystem, systemanalysis, analysisost, ostoligonucleotides, oligonucleotidesconfirmation, confirmationintact, intactpreceding, precedingimpurity, impurityhps, hpsfluidic
307379: Rapid Analysis of Synthetic mRNA Cap Structure using Ion Pairing Reversed Phase LiquidChromatography coupled to Mass SpectrometryJennifer M. Nguyen1, Siu-Hong Chan2, Bijoyita Roy2, Martin Gilar1, Brett Robb2, Weibin Chen1, Matthew A. Lauber11 Waters Corporation, Milford, MA, USA; 2 New...
Key words
synthetic, syntheticoligonucleotides, oligonucleotidesprobe, probernase, rnasemrna, mrnauhplc, uhplcfifth, fifthsurface, surfacecapping, cappingcoupled, coupledheavily, heavilyrna, rnamarked, markedpairing, pairingdispersion
 

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