Adeno-associated virus capsid protein characterization and host cell protein profiling using micro-flow UHPLC-Orbitrap MS
Applications | 2021 | Thermo Fisher ScientificInstrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
IndustriesProteomics
ManufacturerThermo Fisher Scientific
Key wordshcp, aav, peptide, protein, purified, viral, capsid, mapping, harvest, modification, setting, pepsin, abundant, host, protease, sequence, proteins, data, ptm, peak, mass, identification, micro, vanquish, relative, modifications, using, trypsin, aavx, yylnrtqnqsgsaqnkdll, high, offered, phosphorylation, peptides, flow, base, cell, poros, ptms, maximum, raav, characterization, max, chain, low, quantification, thermo, width, sensitivity, digested
Similar PDF
Adeno-Associated Virus Host Cell Protein Profiling Using Micro-flow Separation on a UHPLC-HRAM MS Platform
2021|Thermo Fisher Scientific|Posters
Adeno-Associated Virus Host Cell Protein Profiling Using Micro-flow Separation on a UHPLC-HRAM MS Platform Reiko Kiyonami1, Jennifer Sutton1, Kelly Murphy1, Katy Irvin2, Min Du3, 1Thermo Fisher Scientific, San Jose, CA; 2Thermo Fisher Scientific, Frederick, MD; 3Thermo Fisher Scientific, Cambridge, MA…
Key words
hcp, hcpmicro, microbiopharma, biopharmahyperbridge, hyperbridgefinder, finderdata, datareporting, reportingadeno, adenouhplc, uhplcgreat, greatflow, flowoffered, offeredmyristoylated, myristoylatedfilamin, filaminretention
Adeno-Associated Virus Characterization with Agilent 6545XT AdvanceBio LC/Q-TOF and Protein Metrics Byos Software
2022|Agilent Technologies|Applications
Application Note Biopharma/Pharma Adeno-Associated Virus Characterization with Agilent 6545XT AdvanceBio LC/Q-TOF and Protein Metrics Byos Software Authors Wendi A. Hale and Christopher M. Colangelo Agilent Technologies Inc. Lexington, MA, USA Michelle English Protein Metrics Cupertino, CA, USA Abstract This application…
Key words
byos, byosprotein, proteinvariant, variantpeptide, peptideiterative, iterativeaavs, aavsreconstruction, reconstructionaav, aavsva, svaxle, xlemetrics, metricsmapping, mappingintact, intactamino, aminosequence
Advanced Therapeutic Medicinal Products: Adeno-associated Virus (AAV)
2021|Waters|Others
Advanced Therapeutic Medicinal Products: Adeno-associated Virus (AAV) The Promise of Viral Vector Gene Therapy using AAV 7000 Monogenic Diseases 20 of 22 4 Years Children with spinal muscular atrophy (SMA) given the ability to thrive with Zolgensma® (AAV) at 91%…
Key words
aav, aavbioprocess, bioprocessglossary, glossarycapsid, capsidmapping, mappingdiscovery, discoverygene, generegulatory, regulatorydevelopment, developmentspecifications, specificationstherapy, therapyvirus, virusadeno, adenoviral, viraltransduction
Highly sensitive intact mass analysis of AAV capsid proteins using a UHPLC-FLD- HRAM MS platform
2021|Thermo Fisher Scientific|Applications
APPLICATION NOTE 000253 Highly sensitive intact mass analysis of AAV capsid proteins using a UHPLC-FLDHRAM MS platform Authors: Reiko Kiyonami¹, Kristina Srzentić², Rosa Viner¹, Weijing Liu¹, Min Du², Katy Irvin³, Kenneth Thompson³, Chao Yan Liu³, Jon Zmuda³ ¹ Thermo Fisher…
Key words
capsid, capsidaav, aavintact, intactviral, viraltop, topdown, downproteins, proteinsprotein, proteinmass, masssequence, sequenceintensity, intensityvanquish, vanquishrelative, relativethermo, thermofragment