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Greener, Lower Cost Organic Mobile Phase Solvents for the LC-MS Analysis of Intact Biotherapeutic Proteins

 

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CONSIDERATIONS FOR DEVELOPING A GREENER CHROMATOGRAPHIC METHOD Nicholas Santiago, Bonnie A. Alden, Kenneth D. Berthelette, Kimberly Haynes Waters Corporation, Milford, MA, USA 01757 INTRODUCTION RESULTS DISCUSSION Method development for reversed-phase high-performance liquid chromatography (HPLC) separations has traditionally been conducted using…
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[ APPLICATION NOTE ] Automated Protein Modification Characterization of the Intact and Subunit NIST Monoclonal Antibody Reference Standard with Waters UNIFI Scientific Information System Nilini Ranbaduge, Henry Shion, and Ying Qing Yu Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■…
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Agilent-NISTmAb Intact & Subunit Analysis Using Reversed Phase Agilent BioHPLC Columns Application Compendium Contents Agilent-NISTmAb Standard (P/N 5191-5744; 5191-5745) was aliquoted from NISTmAb RM 8671 batch. Quality control (QC) testing is performed using Agilent LC-MS system. QC batch release test…
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BIOPHARMACEUTICAL PLATFORM SOLUTION Key Applications TABLE OF CONTENTS Biopharmaceutical Platform Solution with UNIFI: Key Applications Intact Protein MS Analysis I Peptide Mapping I Released Glycan Analysis I Bioseparations Biotherapeutic proteins – such as monoclonal antibodies (mAbs), biosimilars, and antibody drug…
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unifi, unifibiopharmaceutical, biopharmaceuticaluplc, uplcglycan, glycanacquity, acquityglycoworks, glycoworksplatform, platformglycans, glycanspeptide, peptidebiosimilar, biosimilaranalysis, analysissolution, solutionintact, intactwaters, watersinnovator
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