Sensitive LC-MS/MS Bioanalytical Quantitation of Antisense Oligonucleotides
Applications | 2022 | WatersInstrumentation
LC/MS, LC/MS/MS, LC/QQQ
IndustriesClinical Research
ManufacturerWaters
Key wordsantisense, oligonucleotides, bioanalytical, sensitive, quantitation, premier, tandem, acquity, absolute, waters, hps, maxpeak, oligonucleotide, human, surfaces, requiring, thio, performance, xevo, state, phased, suffering, plasma, routine, bsm, often, sitemap, careers, privacy, clusters, cookie, non, cookies, preferences, quadrupole, incorporate, mass, bioanalysis, spectrometer, technology, careful, application, pairing, high, dna, generating, binding, from, featured, issues
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Improving LC-MS/MS Bioanalytical Quantitation of Oligonucleotides using New High Performance Tandem Quadrupole Mass Spectrometer Suma Veeramachineni1; Suraj Dhungana1; Ying-Qing Yu1; Mark Wrona1; 1Waters Corporation, Milford, MA Introduction Results Improving LC-MS/MS bioanalytical performance especially for ESI negative analytes has been of…
Key words
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Improved Oligonucleotide SPE-LC-MS Analysis Using MaxPeak High Performance Technology
2020|Waters|Applications
Application Note Improved Oligonucleotide SPE-LC-MS Analysis Using MaxPeak High Performance Technology Kathryn Brennan, Mary Trudeau Lame, Michael Donegan, Paul D. Rainville Waters Corporation Abstract The demand for highly selective and sensitive LC-MS bioanalytical assays in support of research and development…
Key words
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Sensitive Bioanalysis of Antisense Oligonucleotides through Mitigation of Non‐specific Binding and Improved LC‐MS/MS Performance
2022|Waters|Posters
T1530 ‐09‐54 Sensitive Bioanalysis of Antisense Oligonucleotides through Mitigation of Non‐specific Binding and Improved LC‐MS/MS Performance Suma Veeramachineni, Mark D Wrona Waters Corporation, Milford, MA CONTACT INFORMATION: [email protected]; [email protected] PURPOSE RESULT(S) Improving LC-MS/MS bioanalytical performance especially for ESI negative analytes…
Key words
eluforsen, eluforsenmipomersen, mipomersenrsd, rsdfomivirsen, fomivirsenaccuracy, accuracynusinersen, nusinersengalnac, galnacoligonucleotide, oligonucleotidepolythymidine, polythymidinestd, stdpremier, premieronts, ontsconc, concmers, mersname
Sensitive Bioanalysis of Antisense Oligonucleotides of Various Lengths and Modifications
2022|Waters|Applications
English Denmark | Application Note Sensitive Bioanalysis of Antisense Oligonucleotides of Various Lengths and Modifications Suma Veeramachineni, Mark D. Wrona Waters Corporation This is an Application Brief and does not contain a detailed Experimental section. Abstract This application brief demonstrates…
Key words
antisense, antisenseoligonucleotides, oligonucleotidesbioanalysis, bioanalysislengths, lengthsmodifications, modificationssensitive, sensitivevarious, variousabsolute, absolutedemonstrates, demonstratessitemap, sitemapenglish, englishcareers, careersprivacy, privacycookie, cookiecookies