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Middle-Down Analyses of Unmodified and Stressed Monoclonal Antibodies Using an Orbitrap Fusion Lumos Tribrid Mass Spectrometer

 

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Poster Note 64778 Top-down Characterization of Monoclonal Antibody on an Orbitrap Fusion Lumos™ Tribrid Mass Spectrometer Seema Sharma, Stephane Houel, Christopher Mullen, Chad Weisbrod, Romain Huguet, John Syka, Dave Horn, Jonathan Josephs, Jae Schwartz, Vlad Zabrouskov Thermo Fisher Scientific, San…
Key words
abundance, abundanceantibody, antibodyfragmentation, fragmentationintact, intactetd, etdrelative, relativemab, mabtop, topdown, downheavy, heavymonoclonal, monoclonaldeglycosylated, deglycosylateduvpd, uvpdpulses, pulsessequence
APPLICATION NOTE 73885 Complete characterization of monoclonal antibodies under native and denaturing conditions Kristina Srzentić1, Eugen Damoc2, Kai Scheffler3, Tom Buchanan4, Krisztina Radi4, Jennifer Sutton1 Thermo Fisher Scientific, 1 Cambridge, Massachusetts, US 2 Bremen, Germany 3 Germering, Germany 4 Hemel…
Key words
intact, intacttrastuzumab, trastuzumabnative, nativehcd, hcdmass, massmab, mabthermo, thermosubunit, subunitdown, downdeconvolution, deconvolutionscientific, scientificsubunits, subunitspeptide, peptidemiddle, middleheavy
Comprehensive Characterization of Monoclonal Antibody and Antibody Drug Conjugate on a Hybrid QuadrupoleOrbitrap Mass Spectrometer Kristina Srzentić1, Eugen Damoc2, Krisztina Radi3, Tom Buchanan3 , Angela Criscuolo2, Jennifer Sutton1 1Thermo Fisher Scientific, Massachusetts, US, 2Thermo Fisher Scientific, Germany, and 3Thermo Fisher…
Key words
herceptin, herceptinchain, chainnative, nativeadc, adcantibody, antibodyintact, intactabundance, abundancemass, masspeptide, peptideiyptngytr, iyptngytrrelative, relativecharacterization, characterizationsigma, sigmamonoclonal, monoclonalmab
MSUM: NEW on Thermo Scientific Orbitrap Fusion Lumos Tribrid MS
2016|Thermo Fisher Scientific|Presentations
NEW on Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ MS Stephane Houel, Ph.D. BioPharma Vertical Marketing The world leader in serving science NEW On Thermo Scientific Orbitrap Fusion Lumos MS in 2017 ADVANCED PEAK DETERMINATION ALGORITHM RESULTS IN SIGNIFICANT IMPROVEMENT IN…
Key words
uvpd, uvpdapd, apdcoverage, coverageunique, uniqueetd, etdnew, newexisting, existinglumos, lumossystems, systemsoptional, optionalpeptide, peptidetrap, trapproteomics, proteomicsdeamidated, deamidatedfragmentation
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