Installation Instruction for ProfIC Vario 2 Cat

Significance of the topic

The ProfIC Vario 2 Cation system provides a comprehensive automated solution for non-suppressed ion chromatography, enabling high throughput and robust routine analysis of cations in diverse matrices. Its integration with inline ultrafiltration and MagIC Net software fosters reliable sample handling and data processing, critical in environmental, food, and quality control laboratories.

Objectives and overview

This bulletin details the step-by-step installation and configuration of the ProfIC Vario 2 Cat system, including hardware assembly, software setup, and method initiation for fully automated cation determination.

Methodology and used instrumentations

The installation begins with MagIC Net software deployment, followed by assembling the 940 Professional IC Vario module, conductivity detector, and Vario/Flex accessory kits. The 858 Professional Sample Processor interfaces via USB and supports inline ultrafiltration cells for sample clarification. Key connections include eluent delivery (e.g., 1.7 mM HNO3/0.7 mM DPA for Metrosep C 4 columns), sample and filtrate capillaries, and waste management. Configuration in MagIC Net defines each device, rack positions, and method parameters, with system purging and column equilibration steps to ensure baseline stability.

• 940 Professional IC Vario
• IC Conductivity Detector
• 858 Professional Sample Processor
• Inline Ultrafiltration Cell
• Accessory Kits: Vario/Flex Basic and ONE
• Metrosep C 4 - 150/4.0 column and guard
• Eluent Production Module
• Liquid Handling Station (optional)

Main results and discussion

Using a standard mixture of Li, Na, NH4, K, Mn, Ca, and Mg (5 mg/L), the system achieved baseline separation on Metrosep C 4 with DPA complexation. Precision tests at 2 mg/L showed relative standard deviations from 0.26% (Li) to 3.18% (Ca). Calibration over 1–20 mg/L yielded correlation coefficients above 0.9998 and calibration RSDs below 2%, demonstrating excellent linearity and repeatability.

Benefits and practical applications

The ProfIC Vario 2 Cat offers turnkey automation for cation analysis, combining sample prep, inline filtration, and reliable detection. Its seamless software integration and modular accessories reduce carry-over and labor, enhancing productivity in environmental monitoring, industrial QC, and research labs.

Future trends and potential use

Emerging developments include fully integrated eluent synthesis, advanced sample preparation modules, coupling with mass spectrometry detectors, and AI-driven data analysis for enhanced throughput and real-time decision support. Remote monitoring and cloud-based reporting are poised to further streamline IC workflows.

Conclusion

This application bulletin presents a robust framework for installing and commissioning the ProfIC Vario 2 Cat system, underscoring its performance in automated cation analysis. Its precision, flexibility, and automation capabilities make it a valuable asset across analytical laboratories.

References

Application Bulletin AB-365: Suppressed IC Systems Manual
940 Professional IC Vario Manual
858 Professional Sample Processor Manual
Ultrafiltration Cell Manual
941 Eluent Production Module Manual