Analysis of Peptide/Protein*-Related Impurities Using the Integrated Solution of Bio 2D-LC/Q-TOF in Agilent MassHunter Software
Technical notes | 2022 | Agilent TechnologiesInstrumentation
LC/TOF, LC/HRMS, LC/MS, LC/MS/MS, 2D-LC
IndustriesPharma & Biopharma
ManufacturerAgilent Technologies
Key wordsmhc, time, acquisition, cuts, units, masshunter, deck, hires, shifted, min, peptide, gradient, peak, response, based, dimensional, impurities, obtained, analysis, related, heart, agilent, chromatograms, two, separation, were, loops, can, software, panel, clever, from, protein, asm, parking, cutting, tof, counts, workstation, approximately, sampling, multi, setpoints, inject, indicate, bio, where, section, degraded, liquid
Similar PDF
High-Resolution Sampling 2D-LC for Pharmaceutical Impurity Analysis
2020|Agilent Technologies|Applications
High-Resolution Sampling 2D-LC for Pharmaceutical Impurity Analysis Detection of Impurities Hidden Under the API Peak at Relevant Levels Application Note Small Molecule Pharmaceuticals and Generics Authors Abstract Susanne Stephan and Sonja Krieger The analysis of impurities in low concentrations relative…
Key words
chlorodifluorobenzoic, chlorodifluorobenzoicdimension, dimensionwaste, wasteinsulin, insulinhdr, hdrtime, timediverter, diverterdad, dadimpurities, impuritiesimpurity, impuritydiode, diodecuts, cutssampling, samplingarray, arrayfirst
The Agilent InfinityLab 2D-LC Solution with Active Solvent Modulation
2018|Agilent Technologies|Technical notes
Technical Overview The Agilent InfinityLab 2D-LC Solution with Active Solvent Modulation Achieving Improved Resolution and Sensitivity for Challenging Combinations of Separation Conditions Author Sonja Krieger Agilent Technologies, Inc. Abstract A major challenge during method development in two-dimensional liquid chromatography (2D-LC)…
Key words
asm, asmdeck, deckrplc, rplcbreakthrough, breakthroughfocusing, focusinggradient, gradientsolvent, solventeclipse, eclipsecolumn, columndimensional, dimensionalcapillaries, capillarieszorbax, zorbaxmodulation, modulationpeptides, peptidespartial
Simultaneous Impurity Analysis and Enantioseparation of Atenolol Using Achiral-Chiral 2D-LC
2022|Agilent Technologies|Applications
Application Note Pharma & Biopharma Simultaneous Impurity Analysis and Enantioseparation of Atenolol Using Achiral-Chiral 2D-LC Author Lucas Willmann Agilent Technologies, Inc. Abstract To ensure the quality of drug products, chromatographic separation of synthetic byproducts from active pharmaceutical ingredients (APIs), as…
Key words
atenolol, atenololimpurity, impuritychiral, chiralseparation, separationchromatographic, chromatographicenantioseparation, enantioseparationcut, cutmhc, mhcimpurities, impuritiesphase, phasehypotensive, hypotensiveenantiomeric, enantiomericreversed, reversedopenlab, openlabcds
Analysis of Peptone Samples Using the Agilent InfinityLab 2D‑LC Solutions with Active Solvent Modulation
2019|Agilent Technologies|Applications
Application Note Pharma and Biopharma Analysis of Peptone Samples Using the Agilent InfinityLab 2D‑LC Solutions with Active Solvent Modulation Authors Gerd Vanhoenacker, Pat Sandra, and Koen Sandra Research Institute for Chromatography (RIC) President Kennedypark 26 B-8500 Kortrijk Belgium Sonja Krieger,…
Key words
asm, asmpeptone, peptonemau, maumhc, mhcpeptones, peptonesmin, minresearch, researchdimension, dimensionbreakthrough, breakthroughheart, heartsec, seccutting, cuttingcommercial, commercialrplc, rplchrs