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Application Note Rapid Analysis of Lipid Nanoparticle Components Using BioAccord LC-MS System Giorgis Isaac, Nilini Ranbaduge, Bonnie A. Alden, Colette Quinn, Weibin Chen, Robert S. Plumb Waters Corporation Abstract The recent success of mRNA vaccines for COVID-19 is in part…
Key words
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Analysis of Lipid Nanoparticle Composition
2022|Agilent Technologies|Applications
Application Note Biopharma Analysis of Lipid Nanoparticle Composition Author Sonja Schneider Agilent Technologies, Inc. 0 DLin-MC3-DMA DMG-PEG 2000 DSPC ×102 4.75 4.50 4.25 4.00 3.75 3.50 3.25 3.00 2.75 2.50 2.25 2.00 1.75 1.50 1.25 1.00 0.75 0.50 Cholesterol Response…
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Application Note Lipid Nanoparticle Analysis: Leveraging MS to Reduce Risk Duanduan Han, Kellen DeLaney, Bonnie A. Alden, Robert E. Birdsall, Ying Qing Yu Waters Corporation Abstract Lipid nanoparticles (LNPs) represent an elegant solution in the delivery of gene-based therapeutics that…
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Application Note Characterizing and Monitoring Impurities in Lipid Nanoparticle Components Using the BioAccord™ LC-MS System with waters_connect™ Software Kellen DeLaney, Duanduan Han, Robert E. Birdsall, Ying Qing Yu Waters Corporation Abstract Lipid nanoparticles (LNP) have been used with high efficacy…
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