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Rapid Analysis of Lipid Nanoparticle Components Using BioAccord LC-MS System

 

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LIPID NANOPARTICLES—GET TO KNOW THEM ANALYTICALLY Giorgis Isaac; Nilini Ranbaduge; Bonnie Alden; Colette Quinn; Weibin Chen Waters Corporation, Milford, MA 01757 INTRODUCTION Lipid Nanoparticles (LNPs) The recent success of mRNA vaccines is largely due to their ability to use human…
Key words
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Rapid Analysis and Characterization of Lipid Nanoparticle Components for mRNA Delivery W0930-09-49 Giorgis Isaac, Nilini Ranbaduge, Suraj Dhungana Waters Corporation, 34 Maple Street, Milford, Massachusetts, USA CONTACT INFORMATION: [email protected] PURPOSE Success of mRNA vaccines for SARS-CoV-2 highlight the potential of…
Key words
lipid, lipidnanoparticle, nanoparticlelnp, lnpmrna, mrnacomponents, componentscharacterization, characterizationfour, fourbinary, binarydspc, dspcplot, plotpegylated, pegylatedimpurities, impuritiesquick, quickanalysis, analysisassociated
Rapid Analysis of Lipid Nanoparticle Components Using BioAccord™ LC-MS System Giorgis Isaac, Nilini Ranbaduge, Colette Quinn, Weibin Chen and Robert S. Plumb Waters Corporation, Milford, MA Introduction ▪ The recent success of mRNA vaccines in SARSCoV-2 clinical trials is in…
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Application Note Characterizing and Monitoring Impurities in Lipid Nanoparticle Components Using the BioAccord™ LC-MS System with waters_connect™ Software Kellen DeLaney, Duanduan Han, Robert E. Birdsall, Ying Qing Yu Waters Corporation Abstract Lipid nanoparticles (LNP) have been used with high efficacy…
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