ASMS 2021: Rapid Analysis of Lipid Nanoparticle Components Using BioAccord™ LC-MS System | LabRulez LCMS
 

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Application NoteRapid Analysis of Lipid NanoparticleComponents Using BioAccord LC-MS SystemGiorgis Isaac, Nilini Ranbaduge, Bonnie A. Alden, Colette Quinn, Weibin Chen, Robert S. PlumbWaters CorporationAbstractThe recent success of mRNA vaccines for COVID-19 is in part due to the development of lipid...
Key words
lipid, lipidbioaccord, bioaccordlnp, lnpnanoparticle, nanoparticleunifi, unifilnps, lnpsclasses, classescompare, comparedeliver, deliverunknown, unknownimpurities, impuritiesfactorial, factorialthereof, thereoffractional, fractionalfunction
Application NoteLipid Nanoparticle Compositional AnalysisUsing Charged Surface Hybrid Phenyl-HexylSeparation With Evaporative Light ScatteringDetectionBonnie A. Alden, Giorgis Isaac, Weibin Chen, Matthew A. LauberWaters CorporationNeed Help? To learn more about how Waters can help you in your efforts againstCOVID-19, please contact theCOVID-19...
Key words
lipid, lipidhexyl, hexylphenyl, phenylevaporative, evaporativehydrophobicity, hydrophobicityscattering, scatteringstationary, stationaryacquity, acquityhelp, helpnanoparticle, nanoparticlenanoparticles, nanoparticlescsh, cshlight, lightuplc, uplcgarnering
LIPID NANOPARTICLES—GET TO KNOW THEM ANALYTICALLYGiorgis Isaac; Nilini Ranbaduge; Bonnie Alden; Colette Quinn; Weibin ChenWaters Corporation, Milford, MA 01757INTRODUCTIONLipid Nanoparticles (LNPs)The recent success of mRNA vaccines is largely due to their abilityto use human ribosomes to produce the correct protein....
Key words
lipid, lipidlipids, lipidscomplex, complexnanoparticles, nanoparticlesbonnie, bonniecolette, colettegiorgis, giorgisisaac, isaacpivot, pivotspectroscopically, spectroscopicallyalden, aldendspc, dspcnilini, niliniranbaduge, ranbadugebinary
Analysis of Lipid Nanoparticle Composition
2022|Agilent Technologies|Applications
Application NoteBiopharmaAnalysis of LipidNanoparticle CompositionAuthorSonja SchneiderAgilent Technologies, Inc.0DLin-MC3-DMADMG-PEG 2000DSPC×1024.754.504.254.003.753.503.253.002.752.502.252.001.751.501.251.000.750.50CholesterolResponse (LSU)Quaternary method development for highestresolution with evaporative light scattering detection0.5 1.0 1.5 2.0 2.5 3.0 3.5 4.0 4.5 5.0 5.5 6.0 6.5 7.0 7.5 8.0 8.5 9.0 9.5Retention time (min)AbstractLipid nanoparticles...
Key words
dspc, dspclipid, lipidcholesterol, cholesterollsu, lsulnp, lnpchannel, channelmeoh, meohcomponents, componentsfour, fouracn, acnquaternary, quaternaryresponse, responserna, rnaretention, retentionlnps
 

Similar PDF

Toggle
Application NoteRapid Analysis of Lipid NanoparticleComponents Using BioAccord LC-MS SystemGiorgis Isaac, Nilini Ranbaduge, Bonnie A. Alden, Colette Quinn, Weibin Chen, Robert S. PlumbWaters CorporationAbstractThe recent success of mRNA vaccines for COVID-19 is in part due to the development of lipid...
Key words
lipid, lipidbioaccord, bioaccordlnp, lnpnanoparticle, nanoparticleunifi, unifilnps, lnpsclasses, classescompare, comparedeliver, deliverunknown, unknownimpurities, impuritiesfactorial, factorialthereof, thereoffractional, fractionalfunction
Application NoteLipid Nanoparticle Compositional AnalysisUsing Charged Surface Hybrid Phenyl-HexylSeparation With Evaporative Light ScatteringDetectionBonnie A. Alden, Giorgis Isaac, Weibin Chen, Matthew A. LauberWaters CorporationNeed Help? To learn more about how Waters can help you in your efforts againstCOVID-19, please contact theCOVID-19...
Key words
lipid, lipidhexyl, hexylphenyl, phenylevaporative, evaporativehydrophobicity, hydrophobicityscattering, scatteringstationary, stationaryacquity, acquityhelp, helpnanoparticle, nanoparticlenanoparticles, nanoparticlescsh, cshlight, lightuplc, uplcgarnering
LIPID NANOPARTICLES—GET TO KNOW THEM ANALYTICALLYGiorgis Isaac; Nilini Ranbaduge; Bonnie Alden; Colette Quinn; Weibin ChenWaters Corporation, Milford, MA 01757INTRODUCTIONLipid Nanoparticles (LNPs)The recent success of mRNA vaccines is largely due to their abilityto use human ribosomes to produce the correct protein....
Key words
lipid, lipidlipids, lipidscomplex, complexnanoparticles, nanoparticlesbonnie, bonniecolette, colettegiorgis, giorgisisaac, isaacpivot, pivotspectroscopically, spectroscopicallyalden, aldendspc, dspcnilini, niliniranbaduge, ranbadugebinary
Analysis of Lipid Nanoparticle Composition
2022|Agilent Technologies|Applications
Application NoteBiopharmaAnalysis of LipidNanoparticle CompositionAuthorSonja SchneiderAgilent Technologies, Inc.0DLin-MC3-DMADMG-PEG 2000DSPC×1024.754.504.254.003.753.503.253.002.752.502.252.001.751.501.251.000.750.50CholesterolResponse (LSU)Quaternary method development for highestresolution with evaporative light scattering detection0.5 1.0 1.5 2.0 2.5 3.0 3.5 4.0 4.5 5.0 5.5 6.0 6.5 7.0 7.5 8.0 8.5 9.0 9.5Retention time (min)AbstractLipid nanoparticles...
Key words
dspc, dspclipid, lipidcholesterol, cholesterollsu, lsulnp, lnpchannel, channelmeoh, meohcomponents, componentsfour, fouracn, acnquaternary, quaternaryresponse, responserna, rnaretention, retentionlnps
 

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