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PHARMSCI: Rapid Analysis and Characterization of Lipid Nanoparticle Components for mRNA Delivery

 

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Application Note Rapid Analysis of Lipid Nanoparticle Components Using BioAccord LC-MS System Giorgis Isaac, Nilini Ranbaduge, Bonnie A. Alden, Colette Quinn, Weibin Chen, Robert S. Plumb Waters Corporation Abstract The recent success of mRNA vaccines for COVID-19 is in part…
Key words
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Rapid Analysis of Lipid Nanoparticle Components Using BioAccord™ LC-MS System Giorgis Isaac, Nilini Ranbaduge, Colette Quinn, Weibin Chen and Robert S. Plumb Waters Corporation, Milford, MA Introduction ▪ The recent success of mRNA vaccines in SARSCoV-2 clinical trials is in…
Key words
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LIPID NANOPARTICLES—GET TO KNOW THEM ANALYTICALLY Giorgis Isaac; Nilini Ranbaduge; Bonnie Alden; Colette Quinn; Weibin Chen Waters Corporation, Milford, MA 01757 INTRODUCTION Lipid Nanoparticles (LNPs) The recent success of mRNA vaccines is largely due to their ability to use human…
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Application Note Characterizing and Monitoring Impurities in Lipid Nanoparticle Components Using the BioAccord™ LC-MS System with waters_connect™ Software Kellen DeLaney, Duanduan Han, Robert E. Birdsall, Ying Qing Yu Waters Corporation Abstract Lipid nanoparticles (LNP) have been used with high efficacy…
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