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Rapid online buffer exchange - Solutions for high-throughput analysis of large biomolecules by native mass spectrometry

 

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TECHNICAL NOTE Authors: Martin Samonig, Sabrina Patzelt, Martin Rühl, and Remco Swart Thermo Fisher Scientific, Germering, Germany Key words Pre-concentration, trap and elute, desalt, MSPac, MAbPac, monoclonal antibody, mAb, Vanquish, reversed phase, mass spectrometry, Q Exactive, biopharmaceutical, biomolecules, intact protein…
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TECHNICAL NOTE 72203 Tandem UHPLC operation for high-throughput LC-MS peptide mapping analyses Authors Martin Samonig, Sabrina Patzelt, Carsten Paul, Martin Rühl, and Remco Swart Thermo Fisher Scientific, Germering, Germany Keywords Dual column, dual gradient, offline reconditioning, alternating column regeneration, Vanquish…
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TECHNICAL NOTE 72899 Tandem nanoLC-MS: maximum MS utilization for deep-dive proteomic analysis Table of Contents Authors Christopher Pynn , Alexander Boychenko1, Wim Decrop1, Mike Baynham2, Peter Jehle1, Martin Ruehl1 1 Thermo Fisher Scientific, Germering, Germany 1 Thermo Fisher Scientific, Runcorn,…
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TECHNICAL NOTE 73298 Flexible HPLC instrument setups for double usage as one heart-cut-2D-LC system or two independent 1D-LC systems Authors: Maria Grübner and Giorgia Greco Thermo Fisher Scientific, Germering, Germany Keywords: Two-dimensional liquid chromatography, 2D-LC, 2D-HPLC, heart-cut-2D-LC, Vanquish Duo UHPLC…
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