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High-sensitivity low-nano flow LC-MS methods for high-throughput sample-limited proteomics

Applications | 2023 | Thermo Fisher ScientificInstrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Industries
Proteomics
Manufacturer
Thermo Fisher Scientific
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A high-sensitivity high-throughput LCMS platform for single-cell proteomics and low sample amount analysis Runsheng Zheng1, Christopher Pynn1, Manuel Matzinger2, Karl Mechtler2, Alexander Makarov3, Wim Decrop1, Alec Valenta1, Martin Samonig1 1Thermo Fisher Scientific, Germering, Germany; 2Institute of Molecular Pathology, Vienna, Austria;…
Key words
throughput, throughputlcms, lcmsdda, ddanano, nanosensitivity, sensitivitylsa, lsathermo, thermohigh, highgradient, gradientscp, scplow, lowlfq, lfqlength, lengthproteomics, proteomicsscientific
Technical note | 002780 Omics Deeper proteome coverage and faster throughput for single-cell samples on the Orbitrap Astral mass spectrometer Goal Authors To assess proteome coverage and sample throughput performance for single-cell Tabiwang N. Arrey1, Santosh Renuse2, Jenny Ho ,…
Key words
astral, astralorbitrap, orbitrapdia, diamass, massfaims, faimswindow, windowspectrometer, spectrometerlibrary, librarydata, datamaximum, maximumdilution, dilutionneo, neohela, helathermo, thermoprotein
Technical note | 002255 Mass spectrometry Deeper proteome coverage and faster throughput for low input samples on the Thermo Scientific Orbitrap Astral mass spectrometer Authors Goal Santosh Renuse1, Eugen Damoc2, To assess proteome coverage and sample throughput performance for low…
Key words
astral, astralorbitrap, orbitrapprotein, proteindia, diascientific, scientificthermo, thermomass, massspectrometer, spectrometerneo, neodigest, digestcoverage, coveragefaims, faimslow, lowhela, helaproteome
TECHNICAL NOTE LC-MS Vanquish Neo UHPLC system-to-system reproducibility ensures consistent and reliable results in nanoLC-MS proteomics Authors We investigated the intra- and inter-system variability for typical nanoLC-MS applications using the new Vanquish Neo UHPLC Christopher Pynn , Gisela Noack ,…
Key words
neo, neopeptide, peptidevanquish, vanquishwash, washprtc, prtcsystem, systemuhplc, uhplcnanolc, nanolcdigest, digestreproducibility, reproducibilitycytochrome, cytochromeprotein, proteinouter, outerretention, retentionscan
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