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A high-sensitivity high-throughput LCMS platform for single-cell proteomics and low sample amount analysis

Posters |  | Thermo Fisher ScientificInstrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
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Proteomics
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Thermo Fisher Scientific
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Technical note | 001939 Proteomics High-sensitivity low-nano flow LC-MS methods for high-throughput sample-limited proteomics Authors Goal Runsheng Zheng, Alec Valenta, Demonstrate high-throughput and high-sensitivity nano-flow LC-MS methods using a Christopher Pynn, Ece Aydin, 50 μm i.d. column operated at 100…
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Balancing sensitivity and throughput for the analysis of limited sample amounts in proteomics with ultra-low nano-flow LC-MS Runsheng Zheng1; Sun Xuefei2; Karel Stejskal3; Manuel Matzinger4; Christopher Pynn5; Karl Mechtler3, 4, 6; Oleksandr Boychenko1 1Thermo Fisher Scientific, Germering, Germany; 2Thermo Fisher…
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Optimized DDA+ and HR-DIA workflows for standardized, reproducible, precise and robust label-free quantitation of proteomes Aaron S. Gajadhar1, Oleksandr Boychenko2, Xin Zhang3, Yue Xuan4, and Andreas Huhmer1, Thermo Fisher Scientific, San Jose1, CA, USA; Germering, Germany2; Sunnyvale, CA3, USA; Bremen,…
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Optimized one-pot single-cell proteomics workflow
2023|Thermo Fisher Scientific|Applications
Application note | 001933 Proteomics Optimized one-pot single-cell proteomics workflow Maximize a combination of high-confidence coverage and throughput Authors Karl Mechtler Introduction 1,2,3,4 , Manuel Matzinger 1,2,3,4 , David Hartlmayr5, Maciej Bromirski6 Research Institute of Molecular Pathology 1 (IMP), Vienna…
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