Adding Mass Selective Detection to Improve Analytical Sensitivity and Maximize Confidence in Results for Impurity Profiling by UHPLC
Applications | 2017 | Agilent TechnologiesInstrumentation
LC/MS, LC/SQ
IndustriesPharma & Biopharma
ManufacturerAgilent Technologies
Key wordsmsd, enalapril, maleate, api, impurity, impurities, detection, response, agilent, diverter, min, time, detected, tic, mass, purity, waste, chromophores, openlab, library, active, related, valve, diverted, were, profiling, retention, peak, ajs, cds, main, coelution, selective, counts, pharmacopeia, confidence, eic, unexpected, included, searched, elution, area, spectral, infinitylab, chromatogram, percentage, sheath, helps, used, siji
Similar PDF
Using Self-Aware Agilent InfinityLab LC/MSD iQ to Measure Trace-Level Impurities in a Brand Versus Generic Medication
2019|Agilent Technologies|Applications
Application Note Pharma & Biopharma Using Self-Aware Agilent InfinityLab LC/MSD iQ to Measure Trace-Level Impurities in a Brand Versus Generic Medication Author Kyle Covert, PhD Agilent Technologies, Inc. Abstract This study presents a method for comparison of related impurities in…
Key words
otc, otcimpurities, impuritiesapi, apigeneric, genericbrand, brandrelated, relatedmsd, msdamount, amountdrug, drugdetected, detectedarea, areadivert, divertacetaminophen, acetaminophenimpurity, impuritywere
High-Resolution Sampling 2D-LC for Pharmaceutical Impurity Analysis
2020|Agilent Technologies|Applications
High-Resolution Sampling 2D-LC for Pharmaceutical Impurity Analysis Detection of Impurities Hidden Under the API Peak at Relevant Levels Application Note Small Molecule Pharmaceuticals and Generics Authors Abstract Susanne Stephan and Sonja Krieger The analysis of impurities in low concentrations relative…
Key words
chlorodifluorobenzoic, chlorodifluorobenzoicdimension, dimensioninsulin, insulinwaste, wastehdr, hdrtime, timediverter, diverterdad, dadimpurities, impuritiesimpurity, impuritydiode, diodecuts, cutssampling, samplingarray, arrayfirst
Rapid Confirmation of the Purity of APIs Using the Agilent LC/MSD iQ Mass Selective Detector and WalkUp Software
2019|Agilent Technologies|Applications
Application Note Pharma & Biopharma Rapid Confirmation of the Purity of APIs Using the Agilent LC/MSD iQ Mass Selective Detector and WalkUp Software Authors Kyle Covert and Robert Ley Agilent Technologies, Inc. Abstract This application note demonstrates how the addition…
Key words
walkup, walkuppurity, puritymsd, msdmass, masssubmitters, submittersapi, apiopenlab, openlabsample, samplecds, cdscaptopril, captoprildecisions, decisionscomplexities, complexitiesstandards, standardsagilent, agilenttarget
Trace Level Quantification of Potential Mutagenic Impurities in Pharmaceuticals
2019|Agilent Technologies|Applications
Application Note Pharma & Biopharma Trace Level Quantification of Potential Mutagenic Impurities in Pharmaceuticals Using an Agilent Ultivo LC/TQ with mixed mode data acquisition Authors Theresa Sosienski and Kyle Covert Agilent Technologies, Inc. Abstract This Application Note highlights an analytical…
Key words
isonicotinamide, isonicotinamideultivo, ultivoacquisition, acquisitionmutagenic, mutagenicmixed, mixedimpurities, impuritiesquantitation, quantitationdalfampridine, dalfampridinemrm, mrmagilent, agilentapi, apipotential, potentialpmi, pmimode, modescan