Fraction Analysis of Cysteine‑Linked Antibody-Drug Conjugates Using Hydrophobic Interaction Chromatography
Applications | 2017 | Agilent TechnologiesInstrumentation
HPLC
IndustriesClinical Research
ManufacturerAgilent Technologies
Key wordsfraction, hic, brentuximab, mau, vedotin, collection, fractionation, collector, fractions, hydrophobic, antibody, min, conjugates, cysteine, drug, wash, time, slope, using, peak, based, threshold, conjugation, linked, thresholds, interaction, small, conjugated, adc, reversed, collected, main, phase, diode, analysis, openlab, chemstation, chromatogram, adcetris, array, bio, peaks, stop, after, chain, heterogenous, cds, disabling, optimal, rises
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brentuximab, brentuximabvedotin, vedotindar, darhic, hicdrug, drugantibody, antibodyhydrophobic, hydrophobicmmae, mmaeadcs, adcsadc, adctige, tigeinteraction, interactionmab, mablinked, linkedtrastuzumab
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brentuximab, brentuximabvedotin, vedotinisopropanol, isopropanolhic, hicternary, ternarydar, darspecies, speciesantibody, antibodybio, bioorganic, organicdrug, drugbuffers, bufferssolvent, solventsalt, saltadcs
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dar, darhic, hicbrentuximab, brentuximabvedotin, vedotinantibody, antibodydrug, drugsubtraction, subtractionbiocompatible, biocompatiblearea, areaadc, adcsalt, saltmolecules, moleculesmau, mauprecision, precisionspecies
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dimension, dimensiondar, daradcs, adcsadc, adcsecond, secondnative, nativehic, hicadvancebio, advancebiocounts, countsmab, mabdrug, drugdeconvoluted, deconvolutedfirst, firstconjugated, conjugatedintact