DATA INDEPENDENT TOP-DOWN MASS SPECTROMETRY FACILITATED BY A NEW MSE PROCESSING TOOL
Posters | 2019 | WatersInstrumentation
LC/TOF, LC/HRMS, LC/MS, LC/MS/MS
IndustriesManufacturerWaters
Key wordstop, down, mse, proteins, demonstrated, processing, sum, sliding, coverage, scores, sequence, characterization, gaussianexponential, grppr, imtbx, scanbyscan, data, approach, strategy, translationally, low, using, fragments, triwave, independent, avenue, deconvolved, chromatographic, modified, prosight, window, approached, traditional, uvpd, confidence, second, contacting, truncation, abundance, hdmse, envelope, pcs, ides, best, often, synapt, tool, myoglobin, methods, multiply
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Bf Complete biotherapeutic characterization BioPharma Finder Software Transform MS data into actionable results with comprehensive, workflow-driven software Thermo Scientific™ BioPharma Finder™ software provides comprehensive, automated data-processing workflows for the characterization of biologics including peptide mapping, HCP analysis, multi-attribute method (MAM)…
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sequence, sequencemrna, mrnaoligonucleotide, oligonucleotidefinder, finderbiopharma, biopharmadata, datamodifications, modificationssoftware, softwarevisualize, visualizefragment, fragmentcoverage, coverageproteoforms, proteoformsabundance, abundanceprocessing, processingtop
Complete characterization of monoclonal antibodies under native and denaturing conditions
2021|Thermo Fisher Scientific|Applications
APPLICATION NOTE 73885 Complete characterization of monoclonal antibodies under native and denaturing conditions Kristina Srzentić1, Eugen Damoc2, Kai Scheffler3, Tom Buchanan4, Krisztina Radi4, Jennifer Sutton1 Thermo Fisher Scientific, 1 Cambridge, Massachusetts, US 2 Bremen, Germany 3 Germering, Germany 4 Hemel…
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intact, intacttrastuzumab, trastuzumabnative, nativemass, masshcd, hcdmab, mabthermo, thermosubunit, subunitdown, downdeconvolution, deconvolutionscientific, scientificsubunits, subunitspeptide, peptidemiddle, middleheavy
ASMS: Optimization of LC/MS Intact /Top-Down Protein Analysis on an Orbitrap Fusion Mass Spectrometer
2015|Thermo Fisher Scientific|Posters
proteins on a proteomics scale is challenging and requires significant method optimization of front–end separation, instrument parameters and data analysis. In this study, we developed a general RP-LC-MS method for intact/ top-down analysis on an Orbitrap Fusion mass spectrometer using…
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protein, proteinfusion, fusionintact, intacttop, toporbitrap, orbitrapfigure, figuredown, downenolase, enolasefragmentation, fragmentationmixture, mixtureproteins, proteinsyeast, yeasthorse, horsewere, wereethcd
ASMS: Improvements to ProSightPD nodes in the Thermo Scientific Proteome Discoverer Software Framework
2018|Thermo Fisher Scientific|Posters
Improvements to ProSightPD nodes in the Thermo Scientific Proteome Discoverer Software Framework David M. Horn,1 Tara L. Schroeder,1 Ioanna Ntai,1 Richard D. Leduc,2 Ryan T. Fellers,2 Joseph B. Greer,2 and Neil L. Kelleher2, 1Thermo Fisher Scientific, San Jose, CA, 2Northwestern…
Key words
sliding, slidingdeconvolution, deconvolutionhuman, humanprosightpd, prosightpdhigh, highsearch, searchnodes, nodesproteoforms, proteoformsuniprot, uniprotwindow, windowprotein, proteinproteome, proteomeproteoform, proteoformmouse, mousewere