An Efficient Workflow for Identification and Monitoring of Host Cell Proteins During Monoclonal Antibody Bioprocessing

 

Similar PDF

Toggle
AN EFFICIENT LC-MS WORKFLOW FOR IDENTIFICATION AND MONITORING OF HOST CELL PROTEINS FOR ASSISTING MONOCLONAL ANTIBODY PURIFICATION Catalin Doneanu1, Malcolm Anderson2, Alex Xenopoulos3, Romas Skudas4, Ying Qing Yu1, Asish Chakraborty1 and Weibin Chen1 1 Waters Corporation, Milford, MA, USA;2Waters Corporation,…
Key words
hcp, hcpscx, scxprotocol, protocolassays, assaysdiscovery, discoveryprotein, proteinhcps, hcpsmab, mabpeptide, peptideidentification, identificationsqvqasyftk, sqvqasyftkidentified, identifiedtlhqskpvtitvqgpk, tlhqskpvtitvqgpkprotocols, protocolsworkflow
[ APPLICATION NOTE ] A Comprehensive Approach for HCP Identification, Quantification, and Monitoring Based on a Single Dimension (1D) LC Separation Catalin Doneanu, 1 Sarah Lennon, 2 Malcolm Anderson, 2 Ian Reah, 3 Mal Ross, 3 Steven Anderson, 3 Ian…
Key words
biphosphate, biphosphatealdolase, aldolasefructose, fructosehcp, hcpsonar, sonarhcps, hcpstpqiqvysr, tpqiqvysrtvywdrdm, tvywdrdmmse, msehost, hostnote, noteaddgrpfpqvik, addgrpfpqvikphpypaltpeqk, phpypaltpeqksqvqasytfk, sqvqasytfktlhqskpvtitvqgpk
Application Note Identification of Host Cell Proteins (HPCs) in Monoclonal Antibodies At Sub-ppm Levels Using the SYNAPT XS Mass Spectrometer Catalin E. Doneanu, Alexandre Gomes, Brad J. Williams, Ying Qing Yu, Weibin Chen Waters Corporation Abstract In this application note…
Key words
hcp, hcphdmse, hdmsehcps, hcpssynapt, synaptdiscovery, discoveryassay, assayhighly, highlyhost, hostacquisition, acquisitionhpcs, hpcsudmse, udmsesensitive, sensitivemonoclonal, monoclonallut, lutsub
IDENTIFICATION AND QUANTIFICATION OF HOST CELL PROTEIN IMPURITIES IN HIGH PURITY MONOCLONAL ANTIBODIES DOWN TO 1 PPM: AN INTER-LABORATORY STUDY Catalin Doneanu1, Scott J. Berger1, Malcolm Anderson2, Brad Williams3, Matt Lauber1, Asish Chakraborty1 and Weibin Chen1 1 Waters Corporation, Milford,…
Key words
hcps, hcpshcp, hcpmab, mabmse, mseims, imsiaifgatgr, iaifgatgrlchdmse, lchdmsemaeerqdalr, maeerqdalrmobility, mobilitylcmse, lcmsenist, nistreference, referencepeptide, peptideremicade, remicadehdmse
Other projects
Follow us
More information
WebinarsAbout usContact usTerms of use
LabRulez s.r.o., all rights reserved.